BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0547.0052.p (491 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value BS_cad [E] COG1982 Arginine/lysine/ornithine decarboxylases 627 e-180 BH2640 [E] COG1982 Arginine/lysine/ornithine decarboxylases 614 e-175 CAC2338 [E] COG1982 Arginine/lysine/ornithine decarboxylases 449 e-126 CAC0297 [E] COG1982 Arginine/lysine/ornithine decarboxylases 242 1e-63 BS_yaaO [E] COG1982 Arginine/lysine/ornithine decarboxylases 238 1e-62 >BS_cad [E] COG1982 Arginine/lysine/ornithine decarboxylases Length = 204 Score = 627 bits (1618), Expect = e-180, Method: Compositional matrix adjust. Identities = 0/492 (0%), Positives = 0/492 (0%), Gaps = 5/492 (1%) Query: 1 MDQHVTPLFTALKKHAAGNPVQFHIPGHKKGLGTDAEFREFIGDNALSIDLINIAPLDDL 60 M + + + D E + I++ + +L Sbjct: 1 MGKTSMIHAIVDQYSHCEWVENSMSANENNLIWIDLEMTGLDPERDRIIEIATLVTDANL 60 Query: 61 HQPTGVILEAQKLAAEAFGADYTYFSVQGTSNAIMTMILSVCSEGDKIIVPRNIHKSVMS 120 + A + E + T++ ++ + + + + Sbjct: 61 NILAEGPTIAVHQSDEQLALMDDWNVRTHTASGLVERVKASTMGDREAELATLEFLKQWV 120 Query: 121 AIIFSGAKPVFVSPVQDENLGIDHGITTSALEKALRRHPDAKGVLVINPTYFGVCADLRS 180 S + + + + L + P + Sbjct: 121 PAGKSPICGNSIGQDRRFLFKYMPELEAYFHYRYLDVSTLKELARRWKPEILDGFTKQGT 180 Query: 181 IVDLAHSYGVPVLVDEAHGVLIHFHEDLPVSAMQAGADLAATSVHKLGGSMTQSSVLNLN 240 Sbjct: 181 - 239 Query: 241 AKTGLVNPQRVQXXXXXXXXXXXXXXXXXXXDTSRRNLALNGHEMAARTIALSNYARDAI 300 Sbjct: 240 - 298 Query: 301 NNIDGLYSFGKEILGTEATFNIDPTKLNIHVRHLGITGYETENWLREKYKIEVELSDMYN 360 Sbjct: 299 358 Query: 361 ILCLITPGDTQESVDKLISALRVLSAVHYSKGEIYELKVQV--PEIPQLALIPRDAFYAD 418 Sbjct: 359 - 417 Query: 419 TQVVPFRESAGYIIAEFIYVYPPGIPILLPGEVITQDNIDYIIDHVEIGLPVKGPEDRSI 478 Sbjct: 418 477 Query: 479 NYVKVIVEAEPI 490 Sbjct: 478 489 >BH2640 [E] COG1982 Arginine/lysine/ornithine decarboxylases Length = 204 Score = 614 bits (1583), Expect = e-175, Method: Compositional matrix adjust. Identities = 0/489 (0%), Positives = 0/489 (0%), Gaps = 3/489 (0%) Query: 3 QHVTPLFTALKKHAAGNPVQFHIPGHKKGLGTDAEFREFIGDNALSIDLINIAPLDDLHQ 62 + H + + + + + Sbjct: 4 TSMIHAIVDQYSHCEWVENSMSANENNLIWIDLEMTGLDPERDRIIEIATLVTDANLNIL 63 Query: 63 PTGVILEAQKLAAEAFGADYTYFSVQGTSNAIMTMILSVCSEGDKIIVPRNIHKSVMSAI 122 G + + + D S + + S + + + K + A Sbjct: 64 AEGPTIAVHQSDEQLALMDDWNVRTHTASGLVERVKASTMGDREAELATLEFLKQWVPAG 123 Query: 123 IFSGAKPVFVSPVQDENLGIDHGITTSALEKALRRHPDAKGVLVINPTYFGVCADLRSIV 182 + + G Sbjct: 124 KSPICGNSIGQDRRFLFKYMPELEAYFHYRYLDVSTLKELARRWKPEILDGFTKQGTHQA 183 Query: 183 DLAHSYGVPVLVDEAHGVLIHFHEDLPVSAMQAGADLAATSVHKLGGSMTQSSVLNLNAK 242 Sbjct: 184 -- 241 Query: 243 TGLVNPQRVQXXXXXXXXXXXXXXXXXXXDTSRRNLALNGHEMAARTIALSNYARDAINN 302 Sbjct: 242 301 Query: 303 IDGLYSFGKEILGTEATFNIDPTKLNIHVRHLGITGYETENWLREKYKIEVELSDMYNIL 362 Sbjct: 302 361 Query: 363 CLITPGDTQESVDKLISALRVLSAVH-YSKGEIYELKVQVPEIPQLALIPRDAFYADTQV 421 Sbjct: 362 421 Query: 422 VPFRESAGYIIAEFIYVYPPGIPILLPGEVITQDNIDYIIDHVEIGLPVKGPEDRSINYV 481 Sbjct: 422 481 Query: 482 KVIVEAEPI 490 Sbjct: 482 490 >CAC2338 [E] COG1982 Arginine/lysine/ornithine decarboxylases Length = 204 Score = 449 bits (1155), Expect = e-126, Method: Compositional matrix adjust. Identities = 0/485 (0%), Positives = 0/485 (0%), Gaps = 3/485 (0%) Query: 1 MDQHVTPLFTALKKHAAGNPVQFHIPGHKKGLGTDAEFREFIGDNALSIDLINIAPLDDL 60 + N + + L+ A L+ L Sbjct: 4 TSMIHAIVDQYSHCEWVENSMSANENNLIWIDLEMTGLDPERDRIIEIATLVTDANLNIL 63 Query: 61 HQPTGVILEAQKLAAEAFGADYTYFSVQGTSNAIMTMILSVCSEGDKIIVPRNIHKSVMS 120 + + + + E + + Sbjct: 64 AEGPTIAVHQSDEQLALMDDWNVRTHTASGLVERVKASTMGDREAELATLEFLKQWVPAG 123 Query: 121 AIIFSGAKPVFVSPVQDENLGIDHGITTSALEKALRRHPDAKGVLVINPTYFGVCADLRS 180 G + + A+ F ++ Sbjct: 124 KSPICGNSIGQDRRFLFKYMPELEAYFHYRYLDVSTLKELARRWKPEILDGFTKQGTHQA 183 Query: 181 IVDLAHSYGVPVLVDEAHGVLIHFHEDLPVSAMQAGADLAATSVHKLGGSMTQSSVLNLN 240 Sbjct: 184 243 Query: 241 AKTGLVNPQRVQXXXXXXXXXXXXXXXXXXXDTSRRNLALNGHEMAARTIALSNYARDAI 300 Sbjct: 244 -- 301 Query: 301 NNIDGLYSFGKEILGTEATFNIDPTKLNIHVRHLGITGYETENWLREKYKIEVELSDMYN 360 Sbjct: 302 361 Query: 361 ILCLITPGDTQESVDKLISALRVLS-AVHYSKGEIYELKVQVPEIPQLALIPRDAFYADT 419 Sbjct: 362 421 Query: 420 QVVPFRESAGYIIAEFIYVYPPGIPILLPGEVITQDNIDYIIDHVEIGLPVKGPEDRSIN 479 Sbjct: 422 481 Query: 480 YVKVI 484 Sbjct: 482 486 >CAC0297 [E] COG1982 Arginine/lysine/ornithine decarboxylases Length = 204 Score = 242 bits (618), Expect = 1e-63, Method: Compositional matrix adjust. Identities = 0/474 (0%), Positives = 0/474 (0%), Gaps = 9/474 (1%) Query: 6 TPLFTALKKHAAGNPVQFHIPGHKKGLG-TDAEFREFIGDNALSIDLINIAPLDDLHQPT 64 T + A+ + + + + I I D Sbjct: 4 TSMIHAIVDQYSHCEWVENSMSANENNLIWIDLEMTGLDPERDRIIEIATLVTDANLNIL 63 Query: 65 GVILEAQKLAAEAFGADYTYFSVQGTSNAIMTMILSVCSEGDKIIVPRNIHKSVMSAIIF 124 ++ A ++V+ + + + + + GD+ + Sbjct: 64 AEGPTIAVHQSDEQLALMDDWNVRTHTASGLVERVKASTMGDREAELATLEFLKQWVPAG 123 Query: 125 SGAKPVFVSPVQDENLGIDHGITTSALEKALRRHPDAKGVLVINPTYFGVCADLRSIVDL 184 L + K + + Sbjct: 124 KSPICGNSIGQDRRFLFKYMPELEAYFHYRYLDVSTLKELARRWKPEILDGFTKQGTHQA 183 Query: 185 AHSYGVPVLVDEAHGVLIHFHEDLPVSAMQAGADLAATSVHKLGGSMTQSSVLNLNAKTG 244 Sbjct: 184 --- 240 Query: 245 LVNPQRVQXXXXXXXXXXXXXXXXXXXDTSRRNLALNGHEMAARTIALSNYARDAINNID 304 Sbjct: 241 300 Query: 305 GLYSFGKEILGTEA-TFNIDPTKLNIHVRHLGITGYETENWLREKYKIEVELSDMYNILC 363 Sbjct: 301 -- 358 Query: 364 LITPGDTQESVDKLISALRVLSAVHYSKGEIYELKVQVPEIPQLALIPRDAFYADTQVVP 423 Sbjct: 359 -- 416 Query: 424 FRESAGYIIAEFIYVYPPGIPILLPGEVITQDNIDYIIDHVEIGLPVKGPEDRS 477 Sbjct: 417 470 >BS_yaaO [E] COG1982 Arginine/lysine/ornithine decarboxylases Length = 204 Score = 238 bits (608), Expect = 1e-62, Method: Compositional matrix adjust. Identities = 0/488 (0%), Positives = 0/488 (0%), Gaps = 49/488 (10%) Query: 6 TPLFTALKKHAAGNPVQFHIPGHKKGLGTDAEFREF--IGDNALSIDLINIAPLDDLHQP 63 + + + D I Sbjct: 3 KTSMIHAIVDQYSHCEWVENSMSANE---NNLIWIDLEMTGLDPERDRIIEIATLVTDAN 59 Query: 64 TGVILEAQKLAAEAFGADYTYFSVQGTSNAIMTMILSVCSEGDKIIVPRNIHKSVMSAII 123 ++ E +A + ++ + Sbjct: 60 LNILAEGPTIAVHQSDEQLALMDDWNVRTHTASGLVERVKASTMGDREAELATLEFLKQW 119 Query: 124 FSGAKPVFVSPVQDENLGIDHGITTSALEKALRRHPDAKGVLVINPTYFGVCADLRSIVD 183 K ++ R+ D + + + D + Sbjct: 120 VPAGKSPICGNSIGQDRRFLFKYMPELEAYFHYRYLDVSTLKELARRWKPEILDGFTKQG 179 Query: 184 LAHSYGVPVLVDEAHGVLIHFHEDLPVSAMQAGADLAATSVHKLGGSMTQSSVLNLNAKT 243 Sbjct: 180 - 238 Query: 244 GLVNPQRVQXXXXXXXXXXXXXXXXXXXDTSRRNLALNGHEMAARTIALSNYARDAINNI 303 Sbjct: 239 --------- 289 Query: 304 DGLYSFGKEILGTEAT------FNIDPTKLNIHVRHLGITGYETENWLREKYKIEVELSD 357 Sbjct: 290 -- 347 Query: 358 MYNILCLITPGDTQ-----------ESVDKLISALRVLSAVHYSKGEIYELKVQ-VPEIP 405 Sbjct: 348 --------- 398 Query: 406 QLALIPRDAFYA-DTQVVPFRESAGYIIAEFIYVYPPGIPILLPGEVITQDNIDYIIDHV 464 Sbjct: 399 ---- 454 Query: 465 EIGLPVKG 472 Sbjct: 455 462 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.319 0.137 0.396 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 35,350,143 Number of extensions: 1444829 Number of successful extensions: 3403 Number of sequences better than 1.0e-05: 42 Number of HSP's gapped: 3405 Number of HSP's successfully gapped: 42 Length of query: 491 Length of database: 38,378,431 Length adjustment: 110 Effective length of query: 381 Effective length of database: 25,691,691 Effective search space: 9788534271 Effective search space used: 9788534271 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 118 (50.1 bits)