BLASTP 2.2.18 [Mar-02-2008]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment: Altschul, Stephen F., 
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= 0547.0051.p
         (428 letters)

Database: COG 
           115,334 sequences; 38,378,431 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

DR1223 [GEPR] COG0477 Permeases of the major facilitator superfa...    58   3e-08
PAB0874 [GEPR] COG0477 Permeases of the major facilitator superf...    52   3e-06
BH0237 [GEPR] COG0477 Permeases of the major facilitator superfa...    50   9e-06

>DR1223 [GEPR] COG0477 Permeases of the major facilitator superfamily
          Length = 428

 Score = 57.8 bits (138), Expect = 3e-08,   Method: Compositional matrix adjust.
 Identities = 39/115 (33%), Positives = 62/115 (53%), Gaps = 8/115 (6%)

Query: 299 GKLVDRIGTTVFLNIGFL---LAAGSLAFFSQVRWL-PLAFCAVALVGISYALILPAWNA 354
           GKL D+    + + +GF    LA G +A    V  L PLA     L G+ YA I P W A
Sbjct: 283 GKLADQGRARLTVTLGFASLALALGGIALRPAVWALYPLAM----LAGLGYAFIAPGWAA 338

Query: 355 FLAKQVPKGERGTVWGLFLTLQGSGMVAGPVISGKLWDTVGHSTPFLASAFVMVL 409
            +A+++P+ +R   WG  +T++  G   GP++ G  + T+G   PF+A + + +L
Sbjct: 339 LVAQRLPEAQRPAAWGTLMTVENLGTSLGPLLGGFAYRTLGVPGPFIAGSGLALL 393


>PAB0874 [GEPR] COG0477 Permeases of the major facilitator superfamily
          Length = 392

 Score = 51.6 bits (122), Expect = 3e-06,   Method: Compositional matrix adjust.
 Identities = 37/132 (28%), Positives = 62/132 (46%)

Query: 290 ITVLALIPAGKLVDRIGTTVFLNIGFLLAAGSLAFFSQVRWLPLAFCAVALVGISYALIL 349
           I  L+  P G   D++G  + + IGF +A  +   F+    LP    A  L G+  A+  
Sbjct: 261 IYALSAYPIGYYSDKVGKKIIITIGFGIAGLASLIFAYANNLPTLLLAFVLYGLYMAIED 320

Query: 350 PAWNAFLAKQVPKGERGTVWGLFLTLQGSGMVAGPVISGKLWDTVGHSTPFLASAFVMVL 409
               A++A    + E+GTV G + T+ G  +    +I G LW T   +  FL SA + V+
Sbjct: 321 TIPRAYMADLAKEFEKGTVIGAYHTVFGVFVFPASIIVGYLWQTYSLTVGFLYSAVMNVI 380

Query: 410 LFGLHMLIVHRT 421
              +  L++  +
Sbjct: 381 AMIMMALLIKES 392


>BH0237 [GEPR] COG0477 Permeases of the major facilitator superfamily
          Length = 387

 Score = 49.7 bits (117), Expect = 9e-06,   Method: Compositional matrix adjust.
 Identities = 39/139 (28%), Positives = 69/139 (49%), Gaps = 7/139 (5%)

Query: 289 GITVLALI--PAGKLVDRIGTTVFLNIGFLLAAGSLAFFSQVRWLPLAFCAVALVGISYA 346
           GIT L +   P  K+ +R+     + +G  L   SL   S +  L LA   +   GI +A
Sbjct: 244 GITALFIFITPLNKVYERLYPGRLVVLGLGLIGVSLMLLSFIHTLSLAVVLMVTYGIGFA 303

Query: 347 LILPAWNAFLAKQVPKGERGTVWGLFLTLQGSGMVAGPVISGKLWDTVGHSTPFLASAFV 406
            + P+ N  ++      +RG  +G+F  +   G+VAG  ISG + + +G   PF+ S   
Sbjct: 304 FVFPSMNQMVSTASQDEDRGKAYGIFYAVFSLGVVAGSFISGVVTELLG--VPFIVSG-- 359

Query: 407 MVLLFGLHMLIVHRTKRKL 425
             L+ G  +L+V  +++++
Sbjct: 360 -CLMLGCSVLLVWLSQKRI 377


  Database: COG
    Posted date:  Aug 3, 2010  9:58 AM
  Number of letters in database: 38,378,431
  Number of sequences in database:  115,334
  
Lambda     K      H
   0.328    0.143    0.443 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 115334
Number of Hits to DB: 28,022,576
Number of extensions: 1081474
Number of successful extensions: 3712
Number of sequences better than 1.0e-05: 20
Number of HSP's gapped: 3717
Number of HSP's successfully gapped: 21
Length of query: 428
Length of database: 38,378,431
Length adjustment: 109
Effective length of query: 319
Effective length of database: 25,807,025
Effective search space: 8232440975
Effective search space used: 8232440975
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.7 bits)
S2: 117 (49.7 bits)