BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0547.0025.p (321 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value BS_ccpA [K] COG1609 Transcriptional regulators 409 e-114 lin1640 [K] COG1609 Transcriptional regulators 354 1e-97 SP1999 [K] COG1609 Transcriptional regulators 308 5e-84 L0143 [K] COG1609 Transcriptional regulators 300 3e-81 SA1557 [K] COG1609 Transcriptional regulators 290 2e-78 >BS_ccpA [K] COG1609 Transcriptional regulators Length = 334 Score = 409 bits (1050), Expect = e-114, Method: Compositional matrix adjust. Identities = 195/315 (61%), Positives = 242/315 (76%) Query: 1 MATVSRVVNNNPNVKPQTRKKVFEAIERLGYRPNAVARGLASKKTTTVGVVIPDISNSIF 60 MATVSRVVN NPNVKP TRKKV EAIERLGYRPNAVARGLASKKTTTVGV+IPDIS+ + Sbjct: 17 MATVSRVVNGNPNVKPTTRKKVLEAIERLGYRPNAVARGLASKKTTTVGVIIPDISSIFY 76 Query: 61 AEIARGIEDIANMYHYNIILCNADKRKEKEIRVINTLLEKQVDGLLFMGGTVTDEHIQAF 120 +E+ARGIEDIA MY YNIIL N+D+ EKE+ ++NT+L KQVDG++FMGG +TDEH+ F Sbjct: 77 SELARGIEDIATMYKYNIILSNSDQNMEKELHLLNTMLGKQVDGIVFMGGNITDEHVAEF 136 Query: 121 QTSAVPIVLCATRDEQGTYPSVDIDHETAAFDAVNTLIRHGHREIAMISGTLQDPANGYA 180 + S VPIVL A+ +EQ PSV ID+E A +DAV L+ GH +IA +SG + +P N Sbjct: 137 KRSPVPIVLAASVEEQEETPSVAIDYEQAIYDAVKLLVDKGHTDIAFVSGPMAEPINRSK 196 Query: 181 RFQGYKKALEAAGIEYQEDLVRIGNYRYESGVEAMKYFLGLKKKPTAVFAATDEMAIGAI 240 + QGYK+ALE A + + E V G+Y Y+SG+EA+++ + L KKPTA+ +ATDEMA+G I Sbjct: 197 KLQGYKRALEEANLPFNEQFVAEGDYTYDSGLEALQHLMSLDKKPTAILSATDEMALGII 256 Query: 241 HSIQDEGLKVPDDFSIISVDNIRMASMVRPLLTTVAQPMYDLGAVAMRLLTKLMKKETVE 300 H+ QD+GL +P+D II DN R++ MVRP L+TV QP YD+GAVAMRLLTKLM KE VE Sbjct: 257 HAAQDQGLSIPEDLDIIGFDNTRLSLMVRPQLSTVVQPTYDIGAVAMRLLTKLMNKEPVE 316 Query: 301 NPRVILPHETILRLS 315 V LPH LR S Sbjct: 317 EHIVELPHRIELRKS 331 >lin1640 [K] COG1609 Transcriptional regulators Length = 335 Score = 354 bits (909), Expect = 1e-97, Method: Compositional matrix adjust. Identities = 168/313 (53%), Positives = 226/313 (72%) Query: 1 MATVSRVVNNNPNVKPQTRKKVFEAIERLGYRPNAVARGLASKKTTTVGVVIPDISNSIF 60 MATVSRVVN NPNVKP TRKKV + I +LGYRPNAVARGLASK+TTTVGV+IPDISN + Sbjct: 16 MATVSRVVNGNPNVKPVTRKKVLDVINQLGYRPNAVARGLASKRTTTVGVIIPDISNVFY 75 Query: 61 AEIARGIEDIANMYHYNIILCNADKRKEKEIRVINTLLEKQVDGLLFMGGTVTDEHIQAF 120 AE+ARGIEDIA MY YNIIL N+D+ ++KE++V+NTLL KQVDG+++MG ++++ + F Sbjct: 76 AELARGIEDIATMYKYNIILSNSDENEDKELQVLNTLLGKQVDGIIYMGERISEQLQEEF 135 Query: 121 QTSAVPIVLCATRDEQGTYPSVDIDHETAAFDAVNTLIRHGHREIAMISGTLQDPANGYA 180 S P+VL D + SV+ID++ A +AV + +GH++IA +SG+L +P N Sbjct: 136 DRSPAPVVLAGAVDMENKLASVNIDYKEATKEAVKRFVDNGHKQIAFVSGSLNEPVNREM 195 Query: 181 RFQGYKKALEAAGIEYQEDLVRIGNYRYESGVEAMKYFLGLKKKPTAVFAATDEMAIGAI 240 + GYK+ALE AGI YQED + Y Y +GV+ + L KKP AV A DE+AIG + Sbjct: 196 KLAGYKEALEEAGITYQEDYIIEAKYNYNAGVKVWEELSALSKKPNAVVVADDELAIGIL 255 Query: 241 HSIQDEGLKVPDDFSIISVDNIRMASMVRPLLTTVAQPMYDLGAVAMRLLTKLMKKETVE 300 ++ D G+KVP++ +++ +N ++ M RP L+T+ QP+YD+GAVAMRLLTKLM E V+ Sbjct: 256 NAALDAGIKVPEELEVMTSNNTKLTLMSRPQLSTIVQPLYDIGAVAMRLLTKLMTNEEVD 315 Query: 301 NPRVILPHETILR 313 VILPH LR Sbjct: 316 EKTVILPHSEKLR 328 >SP1999 [K] COG1609 Transcriptional regulators Length = 336 Score = 308 bits (790), Expect = 5e-84, Method: Compositional matrix adjust. Identities = 161/308 (52%), Positives = 210/308 (68%), Gaps = 3/308 (0%) Query: 1 MATVSRVVNNNPNVKPQTRKKVFEAIERLGYRPNAVARGLASKKTTTVGVVIPDISNSIF 60 MATVSRVVN N NVK TRKKV E I+RL YRPNAVARGLASKKTTTVGVVIP+I+N F Sbjct: 20 MATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNITNGYF 79 Query: 61 AEIARGIEDIANMYHYNIILCNADKRKEKEIRVINTLLEKQVDGLLFMGGTVTDEHIQAF 120 + +A+GI+DIA MY YNI+L N+D+ EKE+ V+NTL KQVDG+++MG +TD+ F Sbjct: 80 SSLAKGIDDIAEMYKYNIVLANSDEDNEKEVSVVNTLFSKQVDGIIYMGYHLTDKIRSEF 139 Query: 121 QTSAVPIVLCATRDEQGTYPSVDIDHETAAFDAVNTLIRHGHREIAMISGTLQDPANGYA 180 S PIVL T D + PSV+ID++ A DAV+ L + R IA +SG L D NG Sbjct: 140 SRSRTPIVLAGTVDVEHQLPSVNIDYKQATIDAVSYLAKENER-IAFVSGPLVDDINGKV 198 Query: 181 RFQGYKKALEAAGIEYQEDLVRIGNYRYESGVEAMKYFLGLKKKPTAVFAATDEMAIGAI 240 R GYK+ L+ AGI Y E LV Y Y+ G + + TA DE+A G + Sbjct: 199 RLVGYKETLKKAGITYSEGLVFESKYSYDDGYALAERLIS--SNATAAVVTGDELAAGVL 256 Query: 241 HSIQDEGLKVPDDFSIISVDNIRMASMVRPLLTTVAQPMYDLGAVAMRLLTKLMKKETVE 300 + + D+G+ VP+DF II+ D+ +++ RP LTT+AQP+YDLGA++MR+LTK+M KE +E Sbjct: 257 NGLADKGVSVPEDFEIITSDDSQISRFTRPNLTTIAQPLYDLGAISMRMLTKIMHKEELE 316 Query: 301 NPRVILPH 308 V+LPH Sbjct: 317 EREVLLPH 324 >L0143 [K] COG1609 Transcriptional regulators Length = 332 Score = 300 bits (767), Expect = 3e-81, Method: Compositional matrix adjust. Identities = 158/315 (50%), Positives = 216/315 (68%), Gaps = 3/315 (0%) Query: 1 MATVSRVVNNNPNVKPQTRKKVFEAIERLGYRPNAVARGLASKKTTTVGVVIPDISNSIF 60 MATVSRVVN N NVK +TR+KV EAI L YRPNAVARGLASK+TTTVGV++P I+++ F Sbjct: 19 MATVSRVVNGNANVKEKTRQKVLEAIAELDYRPNAVARGLASKRTTTVGVILPTITSTYF 78 Query: 61 AEIARGIEDIANMYHYNIILCNADKRKEKEIRVINTLLEKQVDGLLFMGGTVTDEHIQAF 120 A I RG++DI +MY YN+IL N+D EKE +V+ T L KQVDG+++MG ++ ++ + Sbjct: 79 AAITRGVDDIDSMYKYNMILANSDNDVEKEEKVLETFLSKQVDGIVYMGSSLDEKIRTSL 138 Query: 121 QTSAVPIVLCATRDEQGTYPSVDIDHETAAFDAVNTLIRHGHREIAMISGTLQDPANGYA 180 + S P+VL T D PSV+ID+ AA+ + LI G+++IA I G+L+D N Sbjct: 139 KNSRTPVVLVGTIDGDKEIPSVNIDYHLAAYQSTKKLIDSGNKKIAYIMGSLKDVENT-E 197 Query: 181 RFQGYKKALEAAGIEYQEDLVRIGNYRYESGVEAMKYFLGLKKKPTAVFAATDEMAIGAI 240 R GY++AL A IE+ E+LV GNY YE G +A+ L L++ T+ + D +A+G + Sbjct: 198 RMVGYQEALLEANIEFDENLVFEGNYSYEQG-KALAERL-LERGATSAVVSHDTVAVGLL 255 Query: 241 HSIQDEGLKVPDDFSIISVDNIRMASMVRPLLTTVAQPMYDLGAVAMRLLTKLMKKETVE 300 ++ D+G+KVP+DF IIS N + P LT+V QP+YDLGAVAMRLLTKLM KE VE Sbjct: 256 SAMMDKGVKVPEDFEIISGANSPITQYTYPTLTSVNQPLYDLGAVAMRLLTKLMLKEDVE 315 Query: 301 NPRVILPHETILRLS 315 +++L HE R S Sbjct: 316 QNQLVLDHEIFSRRS 330 >SA1557 [K] COG1609 Transcriptional regulators Length = 314 Score = 290 bits (741), Expect = 2e-78, Method: Compositional matrix adjust. Identities = 149/308 (48%), Positives = 198/308 (64%), Gaps = 3/308 (0%) Query: 1 MATVSRVVNNNPNVKPQTRKKVFEAIERLGYRPNAVARGLASKKTTTVGVVIPDISNSIF 60 MATVSRVVN N NVK +T+ KV E I+RL YRPNAVARGLASKKTTTVGV+IPDISN + Sbjct: 1 MATVSRVVNGNQNVKAETKNKVNEVIKRLNYRPNAVARGLASKKTTTVGVIIPDISNIYY 60 Query: 61 AEIARGIEDIANMYHYNIILCNADKRKEKEIRVINTLLEKQVDGLLFMGGTVTDEHIQAF 120 +++ARG+EDIA MY Y+ I+ N+D EKE + N LL KQVDG++F+GGT+T+E + Sbjct: 61 SQLARGLEDIATMYKYHSIISNSDNDPEKEKEIFNNLLSKQVDGIIFLGGTITEEMKELI 120 Query: 121 QTSAVPIVLCATRDEQGTYPSVDIDHETAAFDAVNTLIRHGHREIAMISGTLQDPANGYA 180 S+VP+V+ T + SV+ID AA + LI G + A++ G A Sbjct: 121 NQSSVPVVVSGTNGKDAHIASVNIDFTEAAKEITGELIEKGAKSFALVGGEHSKKAQEDV 180 Query: 181 RFQGYKKALEAAGIEYQEDLVRIGNYRYESGVEAMKYFLGLKKKPTAVFAATDEMAIGAI 240 +G + L G++ + L G Y+ GV+A G P A+ +DE AIG + Sbjct: 181 -LEGLTEVLNKNGLQLGDTLNCSGAESYKEGVKAFAKMKG--NLPDAILCISDEEAIGIM 237 Query: 241 HSIQDEGLKVPDDFSIISVDNIRMASMVRPLLTTVAQPMYDLGAVAMRLLTKLMKKETVE 300 HS D G+KVP++ IIS +N R+ MVRP L++V QP+YD+GAV MRLLTK M E +E Sbjct: 238 HSAMDAGIKVPEELQIISFNNTRLVEMVRPQLSSVIQPLYDIGAVGMRLLTKYMNDEKIE 297 Query: 301 NPRVILPH 308 P V+LPH Sbjct: 298 EPNVVLPH 305 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.319 0.134 0.376 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 22,422,602 Number of extensions: 880642 Number of successful extensions: 3213 Number of sequences better than 1.0e-05: 180 Number of HSP's gapped: 2973 Number of HSP's successfully gapped: 181 Length of query: 321 Length of database: 38,378,431 Length adjustment: 106 Effective length of query: 215 Effective length of database: 26,153,027 Effective search space: 5622900805 Effective search space used: 5622900805 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 116 (49.3 bits)