BLASTP 2.2.18 [Mar-02-2008]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment: Altschul, Stephen F., 
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= 0547.0005.p
         (135 letters)

Database: COG 
           115,334 sequences; 38,378,431 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

BS_ylbB [R] COG0517 FOG: CBS domain                                   136   8e-33
BH2605 [R] COG0517 FOG: CBS domain                                    114   4e-26
BS_yhcV [R] COG0517 FOG: CBS domain                                   105   2e-23
CAC0678 [R] COG0517 FOG: CBS domain                                    90   9e-19
PA2192 [R] COG0517 FOG: CBS domain                                     74   4e-14

>BS_ylbB [R] COG0517 FOG: CBS domain
          Length = 411

 Score =  136 bits (343), Expect = 8e-33,   Method: Compositional matrix adjust.
 Identities = 4/131 (3%), Positives = 19/131 (14%)

Query: 1   MTAQPVCVTLQDNLYEVAVKMRDADTGVIPVVEADGETLIGIITDRDLVIRGYAEKHSGS 60
              + +               R   +      +   +  +                   +
Sbjct: 8   AIEETLPWLSSFGADPAGGMTRLLYSPEWLETQQQFKKRMAASGLETRFDEVGNLYGRLN 67

Query: 61  TAVETVMTKGITAVSESTSVDEAAELMASRQIRRIPVVNGKKLIGIVSLGDLAVKNIFAD 120
                       +  ++       +         + +   K   G        V     +
Sbjct: 68  GTEYPQEVVLSGSHIDTVVNGGNLDGQFGALAAWLAIDWLKTQYGAPLRTVEVVAMAEEE 127

Query: 121 EAAEALTDISQ 131
            +         
Sbjct: 128 GSRFPYVFWGS 138


>BH2605 [R] COG0517 FOG: CBS domain
          Length = 142

 Score =  114 bits (285), Expect = 4e-26,   Method: Compositional matrix adjust.
 Identities = 57/120 (47%), Positives = 85/120 (70%), Gaps = 2/120 (1%)

Query: 12  DNLYEVAVKMRDADTGVIPVVEADGETLIGIITDRDLVIRGYAEKHSGSTAVETVMTKGI 71
           DN++EVAVKM   + G +P+ E   E L+G++TDRD+VIR  A+K   ST V+ VM++ +
Sbjct: 19  DNIFEVAVKMERDNVGAVPICEE--EQLLGMVTDRDIVIRSVAKKKPNSTPVKEVMSEHL 76

Query: 72  TAVSESTSVDEAAELMASRQIRRIPVVNGKKLIGIVSLGDLAVKNIFADEAAEALTDISQ 131
              +   +V EAA+LMA++QIRR+PVV   +L+GI SLGDLAV++    +A  AL++IS+
Sbjct: 77  VTATPDMTVQEAAKLMATKQIRRLPVVENNRLVGICSLGDLAVRDSSDHQAGIALSEISE 136


>BS_yhcV [R] COG0517 FOG: CBS domain
          Length = 140

 Score =  105 bits (261), Expect = 2e-23,   Method: Compositional matrix adjust.
 Identities = 55/135 (40%), Positives = 84/135 (62%), Gaps = 2/135 (1%)

Query: 1   MTAQPVCVTLQDNLYEVAVKMRDADTGVIPVVEADGETLIGIITDRDLVIRGYAEKHSGS 60
           MT Q   V+    + E A  M+  + G IPVVE     L G++TDRD+ +R  A+   G 
Sbjct: 8   MTTQVATVSPNQTIQEAASLMKQHNVGAIPVVEQG--VLKGMLTDRDIALRTTAQGRDGQ 65

Query: 61  TAVETVMTKGITAVSESTSVDEAAELMASRQIRRIPVVNGKKLIGIVSLGDLAVKNIFAD 120
           T V  VM+  + + + + S+++A++LMA  QIRR+P+V+   L+GIV+LGDLAV  +  +
Sbjct: 66  TPVSEVMSTELVSGNPNMSLEDASQLMAQHQIRRLPIVDQNNLVGIVALGDLAVNQMSNE 125

Query: 121 EAAEALTDISQQHLH 135
            A  ALT+IS Q++H
Sbjct: 126 SAGSALTNISHQNIH 140


>CAC0678 [R] COG0517 FOG: CBS domain
          Length = 142

 Score = 90.1 bits (222), Expect = 9e-19,   Method: Compositional matrix adjust.
 Identities = 53/132 (40%), Positives = 78/132 (59%), Gaps = 3/132 (2%)

Query: 1   MTAQPVCVTLQDNLYEVAVKMRDADTGVIPVVEADGETLIGIITDRDLVIRGYAEKHSGS 60
           MT   V V+ ++N+   A  MRD D G IPV  +D   +IG++TDRD+V+R  AE    S
Sbjct: 7   MTKNVVSVSGEENIKRAAELMRDHDIGAIPVCNSD--KVIGVVTDRDIVLRTVAEGSDAS 64

Query: 61  TA-VETVMTKGITAVSESTSVDEAAELMASRQIRRIPVVNGKKLIGIVSLGDLAVKNIFA 119
           +  V ++MT      S      EA ++M+ +Q+RR+PV    KL+G+VSLGD AV+    
Sbjct: 65  SENVRSIMTSTPVVASPDMDAREATKIMSEKQVRRLPVARDGKLVGMVSLGDFAVEGSTD 124

Query: 120 DEAAEALTDISQ 131
           + A +AL+ IS 
Sbjct: 125 NCAEKALSGISS 136


>PA2192 [R] COG0517 FOG: CBS domain
          Length = 137

 Score = 74.3 bits (181), Expect = 4e-14,   Method: Compositional matrix adjust.
 Identities = 47/117 (40%), Positives = 66/117 (56%), Gaps = 3/117 (2%)

Query: 1   MTAQPVCVTLQDNLYEVAVKMRDADTGVIPVVEADGETLIGIITDRDLVIRGYAEKHSGS 60
           M+ +   VT Q  L E A+ MR AD G + V E  GE L G++TDRDL +RG A+     
Sbjct: 7   MSREVRTVTPQTTLGEAALLMRQADIGALLVNE--GERLTGVVTDRDLAVRGLADGLGAD 64

Query: 61  TAVETVMTKGITAVSESTSVDEAAELMASRQIRRIPVVN-GKKLIGIVSLGDLAVKN 116
             V  VM+  +    E   VD   + MA  + RR+PV++  K+L+GIVSL ++A  N
Sbjct: 65  RPVREVMSGELRYCFEDEEVDHVTKNMAQLEKRRLPVMDRNKRLVGIVSLANIATCN 121


  Database: COG
    Posted date:  Aug 3, 2010  9:58 AM
  Number of letters in database: 38,378,431
  Number of sequences in database:  115,334
  
Lambda     K      H
   0.315    0.131    0.348 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 115334
Number of Hits to DB: 9,062,591
Number of extensions: 326921
Number of successful extensions: 1963
Number of sequences better than 1.0e-05: 64
Number of HSP's gapped: 1996
Number of HSP's successfully gapped: 65
Length of query: 135
Length of database: 38,378,431
Length adjustment: 95
Effective length of query: 40
Effective length of database: 27,421,701
Effective search space: 1096868040
Effective search space used: 1096868040
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 110 (47.0 bits)