BLASTP 2.2.18 [Mar-02-2008]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment: Altschul, Stephen F., 
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= 0545.0046.p
         (406 letters)

Database: COG 
           115,334 sequences; 38,378,431 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

SA0628 [GEPR] COG0477 Permeases of the major facilitator superfa...   254   2e-67
VC1261 [GEPR] COG0477 Permeases of the major facilitator superfa...   119   9e-27

>SA0628 [GEPR] COG0477 Permeases of the major facilitator superfamily
          Length = 404

 Score =  254 bits (649), Expect = 2e-67,   Method: Compositional matrix adjust.
 Identities = 147/371 (39%), Positives = 225/371 (60%), Gaps = 5/371 (1%)

Query: 11  IPGYPVFLSCMMLQGMAISISSPFLAVYFTTKLGVSXXXXXXXXXXXXXSGVWLSMWIAQ 70
           I  Y +F++ M L GM I+++ P+L ++ T  LG++             S   ++  IA+
Sbjct: 8   IKNYKLFVANMFLLGMGIAVTVPYLVLFATKDLGMTTNQYGLLLASAAISQFTVNSIIAR 67

Query: 71  RSDSG-LNRKKLMVTAMFFNALAFAGYLLIHEFYGLLLYMAVFTALGAPAMPQLFASARE 129
            SD+   NRK +++ A+   AL F+ Y  +   +  +L  A+F  L APAMPQL+ASARE
Sbjct: 68  FSDTHHFNRKIIIILALLMGALGFSIYFFVDTIWLFILLYAIFQGLFAPAMPQLYASARE 127

Query: 130 AVNASKSADHA-FANSTLRSMFSLGFIAGPLAGSALIHYFGFPGIFMSTVLIFLMNALLI 188
           ++N S S D A FAN+ LRSMFSLGF+ GP  G+ LI   G+ G+F  T+ I L   +L 
Sbjct: 128 SINVSSSKDRAQFANTVLRSMFSLGFLFGPFIGAQLIGLKGYAGLFGGTISIILFTLVLQ 187

Query: 189 MIFVKA--PAAPPQTAGSKQQQQPVRLLQNSRVLIPFLVLTLLYSGHWINNLNISLFITD 246
           + F K      P  T    ++  P  + ++  +L+PF+   LL+ G W+  +N+ LF+TD
Sbjct: 188 VFFYKDLNIKHPISTQQHVEKIAP-NMFKDKTLLLPFIAFILLHIGQWMYTMNMPLFVTD 246

Query: 247 TLGGDTQNVASVSSICALLEIPLMLVLGLLSAKYSARLLMVWGITLGAAYYIVVLFSTSL 306
            L  + Q+V  ++S+CA LE+P M++LG+LS++   R L+++G   G  +Y  +    + 
Sbjct: 247 YLKENEQHVGYLASLCAGLEVPFMIILGVLSSRLHTRTLLIYGAIFGGLFYFSIGVFKNF 306

Query: 307 WQILAGQVLLAFFVAVISAIGISYIQDLLPDLPGYASTLYTNSTTIGRLFGSLAGGAAAQ 366
           + +LAGQV LA F+AV+  IGISY QD+LPD PGYASTL++N+  IG+L G+L GGA + 
Sbjct: 307 YMMLAGQVFLAIFLAVLLGIGISYFQDILPDFPGYASTLFSNAMVIGQLGGNLLGGAMSH 366

Query: 367 WFGYRNAYWVC 377
           W G  N ++V 
Sbjct: 367 WVGLENVFFVS 377


>VC1261 [GEPR] COG0477 Permeases of the major facilitator superfamily
          Length = 404

 Score =  119 bits (298), Expect = 9e-27,   Method: Compositional matrix adjust.
 Identities = 98/367 (26%), Positives = 177/367 (48%), Gaps = 12/367 (3%)

Query: 16  VFLSCMMLQGMAISISSPFLAVYFTTKLGVSXXXXXXXXXXXXXSGVWLSMWIAQRSDSG 75
           +F+   ++ G+  +   P  +++    L  S             S V +S W+A++SD  
Sbjct: 9   LFIMSTLVTGLCGAFFYPLSSLFIVEALDASPMQLSLYMVLAVVSSVIVSQWLARQSDRH 68

Query: 76  LNRKKLMVTAMFFNALAFAGYLLIHEFYGLLLYMAVFTALGAPAMPQLFASAREAVNASK 135
             RK +++ ++    +    ++ I  +   ++ + +F  +   +  QLFA  RE  +   
Sbjct: 69  WQRKTILLVSLICYLITVVSFMFIRSYSLAIMVVVLFANVSGASFGQLFALGREYADQHL 128

Query: 136 SADHAFANSTLRSMFSLGFIAGPLAGSALIHYFGFPGIFMSTVLIFLMNALLIMIFVKAP 195
           +    F  ST+R+  ++ ++ GP A   L   FGF   F  + LI  +  +LI  F+ A 
Sbjct: 129 TDKTTFL-STMRAGIAIAWVFGPPAAFMLKASFGFNAAFAVSALIVFLGIVLIARFLPAG 187

Query: 196 AAPPQTAGSKQQQQPVRLLQNS---RVLIPFLVLTLLYSGHWINNLNIS---LFITDTLG 249
                  G+     PV L Q S   R LI    +TL+ +    NNL I+   L+++  L 
Sbjct: 188 VKTASAVGTT----PVELGQYSPRKRALIVLYCVTLVCT-FGSNNLYITSMPLYLSRELM 242

Query: 250 GDTQNVASVSSICALLEIPLMLVLGLLSAKYSARLLMVWGITLGAAYYIVVLFSTSLWQI 309
                +  +    AL EIP+ML+ G L+ ++    L+++GIT G  +Y V+L  T    +
Sbjct: 243 VPEHWLGLLFGTAALCEIPVMLMAGKLAERWGTNKLLMFGITSGILFYGVMLTHTGFVAM 302

Query: 310 LAGQVLLAFFVAVISAIGISYIQDLLPDLPGYASTLYTNSTTIGRLFGSLAGGAAAQWFG 369
           +A QVL  FF+ V + +G+  +QD++ D  G ASTL+++  +I  L  SL+ G   +++ 
Sbjct: 303 MAAQVLNGFFIGVCATLGMVVLQDMMQDRLGTASTLFSSMLSISTLVASLSVGVVGEFYN 362

Query: 370 YRNAYWV 376
           Y +  +V
Sbjct: 363 YFSTLYV 369


  Database: COG
    Posted date:  Aug 3, 2010  9:58 AM
  Number of letters in database: 38,378,431
  Number of sequences in database:  115,334
  
Lambda     K      H
   0.328    0.139    0.420 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 115334
Number of Hits to DB: 24,798,909
Number of extensions: 869742
Number of successful extensions: 3433
Number of sequences better than 1.0e-05: 7
Number of HSP's gapped: 3453
Number of HSP's successfully gapped: 7
Length of query: 406
Length of database: 38,378,431
Length adjustment: 109
Effective length of query: 297
Effective length of database: 25,807,025
Effective search space: 7664686425
Effective search space used: 7664686425
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.8 bits)
S2: 117 (49.7 bits)