BLASTP 2.2.18 [Mar-02-2008]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment: Altschul, Stephen F., 
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= 0545.0037.p
         (130 letters)

Database: COG 
           115,334 sequences; 38,378,431 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

BH0686 [P] COG2076 Membrane transporters of cations and cationic...    91   3e-19
BS_ykkC [P] COG2076 Membrane transporters of cations and cationi...    81   5e-16
Cj0310c [P] COG2076 Membrane transporters of cations and cationi...    68   4e-12
BS_yvdS [P] COG2076 Membrane transporters of cations and cationi...    59   2e-09
PA3265 [P] COG2076 Membrane transporters of cations and cationic...    53   1e-07

>BH0686 [P] COG2076 Membrane transporters of cations and cationic drugs
          Length = 114

 Score = 91.3 bits (225), Expect = 3e-19,   Method: Compositional matrix adjust.
 Identities = 45/80 (56%), Positives = 56/80 (70%)

Query: 20 NSAWFKIAGAACLEVVWVIGLKHASVPWEWLITGLALLVSFYTIIAASRKLPVGTVYSVF 79
          N  W  +  AA  EV WVIGLKHA  P EW  T LA+++S   +I A+++LPVGTVY+VF
Sbjct: 2  NKQWLMVVTAAVFEVGWVIGLKHADHPLEWGGTALAIVISLSLMILAAKQLPVGTVYAVF 61

Query: 80 VGLGTAGTVLADMLWFGEPF 99
          VGLGTAGTV A+ + F EP 
Sbjct: 62 VGLGTAGTVCAEAVLFAEPL 81


>BS_ykkC [P] COG2076 Membrane transporters of cations and cationic drugs
          Length = 112

 Score = 80.9 bits (198), Expect = 5e-16,   Method: Compositional matrix adjust.
 Identities = 41/76 (53%), Positives = 53/76 (69%)

Query: 23 WFKIAGAACLEVVWVIGLKHASVPWEWLITGLALLVSFYTIIAASRKLPVGTVYSVFVGL 82
          W  +  AA  EVVWVIGLKHA     W  T + ++ SFY ++ A+  LPVGTVY+VF GL
Sbjct: 3  WGLVVLAAVFEVVWVIGLKHADSALTWSGTAIGIIFSFYLLMKATHSLPVGTVYAVFTGL 62

Query: 83 GTAGTVLADMLWFGEP 98
          GTAGTVL++++ F EP
Sbjct: 63 GTAGTVLSEIVLFHEP 78


>Cj0310c [P] COG2076 Membrane transporters of cations and cationic drugs
          Length = 112

 Score = 67.8 bits (164), Expect = 4e-12,   Method: Compositional matrix adjust.
 Identities = 32/85 (37%), Positives = 48/85 (56%)

Query: 14 DSSMKNNSAWFKIAGAACLEVVWVIGLKHASVPWEWLITGLALLVSFYTIIAASRKLPVG 73
          +     N AWF I     +E  WV GLK+++  W++++T + + +SF   + A  +L V 
Sbjct: 2  NEKFNINIAWFLIILGGIIECFWVSGLKYSTEIWQYILTAIGVCISFTCFLKACERLEVS 61

Query: 74 TVYSVFVGLGTAGTVLADMLWFGEP 98
            YSVFVG+GT G VL +M  F E 
Sbjct: 62 ITYSVFVGIGTIGVVLNEMFIFNEA 86


>BS_yvdS [P] COG2076 Membrane transporters of cations and cationic drugs
          Length = 111

 Score = 59.3 bits (142), Expect = 2e-09,   Method: Compositional matrix adjust.
 Identities = 32/77 (41%), Positives = 46/77 (59%), Gaps = 1/77 (1%)

Query: 23 WFKIAGAACLEVVWVIGLKHASVPWEWLITGLALLVSFYTIIAASRKLPVGTVYSVFVGL 82
          W  +  A  LEVVW   LKHA    +W+I  + + VSF  +I + +K+P+   Y+VFVG+
Sbjct: 3  WVLVFIAGLLEVVWASSLKHADSLLDWIIIFILIAVSFILLIRSYQKIPMAAAYTVFVGI 62

Query: 83 GTAGTVLADMLWFGEPF 99
          GT GT L  ++  GE F
Sbjct: 63 GTVGTYLTGIV-LGESF 78


>PA3265 [P] COG2076 Membrane transporters of cations and cationic drugs
          Length = 104

 Score = 52.8 bits (125), Expect = 1e-07,   Method: Compositional matrix adjust.
 Identities = 32/79 (40%), Positives = 48/79 (60%), Gaps = 3/79 (3%)

Query: 22 AWFKIAGAACLEVVWVIGLKHA---SVPWEWLITGLALLVSFYTIIAASRKLPVGTVYSV 78
          +W  +  A   EV W +GLK+    S P   ++T LA+LVS   +  A + LP+GT Y+V
Sbjct: 2  SWIILFFAGLFEVGWAVGLKYTEGFSKPLPTVLTALAMLVSLGLLGLAMKHLPLGTAYAV 61

Query: 79 FVGLGTAGTVLADMLWFGE 97
          + G+G  GTV+A ++ FGE
Sbjct: 62 WTGVGAVGTVIAGIVLFGE 80


  Database: COG
    Posted date:  Aug 3, 2010  9:58 AM
  Number of letters in database: 38,378,431
  Number of sequences in database:  115,334
  
Lambda     K      H
   0.324    0.137    0.444 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 115334
Number of Hits to DB: 8,191,997
Number of extensions: 248270
Number of successful extensions: 827
Number of sequences better than 1.0e-05: 19
Number of HSP's gapped: 818
Number of HSP's successfully gapped: 19
Length of query: 130
Length of database: 38,378,431
Length adjustment: 94
Effective length of query: 36
Effective length of database: 27,537,035
Effective search space: 991333260
Effective search space used: 991333260
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 109 (46.6 bits)