BLASTP 2.2.18 [Mar-02-2008]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment: Altschul, Stephen F., 
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= 0545.0036.p
         (104 letters)

Database: COG 
           115,334 sequences; 38,378,431 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

BH0685 [P] COG2076 Membrane transporters of cations and cationic...   110   4e-25
BS_ykkD [P] COG2076 Membrane transporters of cations and cationi...    89   2e-18
lin0847 [P] COG2076 Membrane transporters of cations and cationi...    74   8e-14
YPO0355 [P] COG2076 Membrane transporters of cations and cationi...    65   3e-11
Cj0309c [P] COG2076 Membrane transporters of cations and cationi...    63   1e-10

>BH0685 [P] COG2076 Membrane transporters of cations and cationic drugs
          Length = 104

 Score =  110 bits (276), Expect = 4e-25,   Method: Compositional matrix adjust.
 Identities = 56/104 (53%), Positives = 69/104 (66%)

Query: 1   MDWLMLIAAGCCEMLGVAMLGKLQRDRTWPTFCXXXXXXXXXXXXXXQAMNTLPMGTAYA 60
           M W++LIAAG CEM+GV M+ +L R R+W  +                AM +L MGTAYA
Sbjct: 1   MAWVILIAAGLCEMVGVLMINQLHRSRSWKAYAGMIIGFGLSFWLLAMAMQSLSMGTAYA 60

Query: 61  VWTGIGASGGAVLGMLLYGEGRELRRIICIVMILGAAVGLKLLG 104
           VWTGIGASGGA+LGML Y E R+  RIICI +IL A +GLK +G
Sbjct: 61  VWTGIGASGGALLGMLFYDEPRQTLRIICIALILAATIGLKFIG 104


>BS_ykkD [P] COG2076 Membrane transporters of cations and cationic drugs
          Length = 105

 Score = 89.0 bits (219), Expect = 2e-18,   Method: Compositional matrix adjust.
 Identities = 44/104 (42%), Positives = 64/104 (61%)

Query: 1   MDWLMLIAAGCCEMLGVAMLGKLQRDRTWPTFCXXXXXXXXXXXXXXQAMNTLPMGTAYA 60
           + W+ L+ AGC EM GVA++ +  ++++                    AM T PMGTAYA
Sbjct: 2   LHWISLLCAGCLEMAGVALMNQYAKEKSVKWVLLIIVGFAASFSLLSYAMETTPMGTAYA 61

Query: 61  VWTGIGASGGAVLGMLLYGEGRELRRIICIVMILGAAVGLKLLG 104
           VWTGIG +GGA++G+L Y E ++ +RI  I +IL +AVGLK+L 
Sbjct: 62  VWTGIGTAGGALIGILFYKEQKDAKRIFFIALILCSAVGLKILS 105


>lin0847 [P] COG2076 Membrane transporters of cations and cationic drugs
          Length = 106

 Score = 73.6 bits (179), Expect = 8e-14,   Method: Compositional matrix adjust.
 Identities = 41/103 (39%), Positives = 57/103 (55%), Gaps = 2/103 (1%)

Query: 1   MDWLMLIAAGCCEMLGVAMLGKLQRDRTWPTFCXXXXXXXXXXXXXXQ-AMNTLPMGTAY 59
           MDW+ L+ AG CEM+ V ML KL        F                 A+ T+P+GT Y
Sbjct: 1   MDWIFLLVAGLCEMVFVVML-KLSDGFKRLGFAILTVIFMSASFFLLSLALKTIPIGTGY 59

Query: 60  AVWTGIGASGGAVLGMLLYGEGRELRRIICIVMILGAAVGLKL 102
           A+WTGIGA G   LGM+++ E + + +++ I MI+   VGLKL
Sbjct: 60  AIWTGIGAVGSVTLGMIVFKERKSVGKLLFITMIIAGVVGLKL 102


>YPO0355 [P] COG2076 Membrane transporters of cations and cationic drugs
          Length = 104

 Score = 65.1 bits (157), Expect = 3e-11,   Method: Compositional matrix adjust.
 Identities = 40/103 (38%), Positives = 56/103 (54%), Gaps = 2/103 (1%)

Query: 1   MDWLMLIAAGCCEML-GVAMLGKLQRDRTWPTFCXXXXXXXXXXXXXXQAMNTLPMGTAY 59
           M W++L+ AG  E++  + +       R  P+                 AM +LP GTAY
Sbjct: 1   MAWIILVIAGLLEVIWAIGLKYSHGFSRLTPSIITLVAMAASVFLLA-YAMKSLPAGTAY 59

Query: 60  AVWTGIGASGGAVLGMLLYGEGRELRRIICIVMILGAAVGLKL 102
           AVWTGIGA G A+LG++L GE   L RI+ + +IL   +GLKL
Sbjct: 60  AVWTGIGAVGTAILGIVLLGESASLARILSLGLILAGIIGLKL 102


>Cj0309c [P] COG2076 Membrane transporters of cations and cationic drugs
          Length = 104

 Score = 62.8 bits (151), Expect = 1e-10,   Method: Compositional matrix adjust.
 Identities = 30/104 (28%), Positives = 48/104 (46%)

Query: 1   MDWLMLIAAGCCEMLGVAMLGKLQRDRTWPTFCXXXXXXXXXXXXXXQAMNTLPMGTAYA 60
           M+W  L  A  CE+ GV ++ +L   +                     +M  + M  AYA
Sbjct: 1   MEWFYLFLATACEIFGVVIMKELVSTKNKLYLLALIVCFGFSFTFLSLSMQNIAMSVAYA 60

Query: 61  VWTGIGASGGAVLGMLLYGEGRELRRIICIVMILGAAVGLKLLG 104
           +WTG G +GG ++G+L Y E +   ++  I +I+    GLK L 
Sbjct: 61  IWTGAGTAGGVMIGVLFYKESKSFLKLFLIAVIITCTAGLKFLS 104


  Database: COG
    Posted date:  Aug 3, 2010  9:58 AM
  Number of letters in database: 38,378,431
  Number of sequences in database:  115,334
  
Lambda     K      H
   0.329    0.144    0.472 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 115334
Number of Hits to DB: 6,464,896
Number of extensions: 182810
Number of successful extensions: 663
Number of sequences better than 1.0e-05: 19
Number of HSP's gapped: 661
Number of HSP's successfully gapped: 19
Length of query: 104
Length of database: 38,378,431
Length adjustment: 72
Effective length of query: 32
Effective length of database: 30,074,383
Effective search space: 962380256
Effective search space used: 962380256
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.8 bits)
S2: 109 (46.6 bits)