BLASTP 2.2.18 [Mar-02-2008]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment: Altschul, Stephen F., 
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= 0545.0010.p
         (165 letters)

Database: COG 
           115,334 sequences; 38,378,431 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

alr3102 [R] COG2179 Predicted hydrolase of the HAD superfamily         81   7e-16
alr3507 [R] COG2179 Predicted hydrolase of the HAD superfamily         76   2e-14
STM0171 [P] COG0288 Carbonic anhydrase                                 70   1e-12
PH1655 [R] COG1011 Predicted hydrolase (HAD superfamily)               53   3e-07

>alr3102 [R] COG2179 Predicted hydrolase of the HAD superfamily
          Length = 359

 Score = 80.9 bits (198), Expect = 7e-16,   Method: Compositional matrix adjust.
 Identities = 7/128 (5%), Positives = 25/128 (19%)

Query: 18  RGIITDLDNTLVGAKAPLATPELLLWFAKVKELGFKLIIVSNNNMDRVSRFATPLNIEFV 77
             +  +     +   A           A+++E            +  +  F    ++  +
Sbjct: 31  AVVKANAYGHGLLETARTLPDADAFGVARLEEALRLRAGGITKPVLLLEGFFDARDLPTI 90

Query: 78  HQARKPSNTPFLKAMKQMGLTPEQTIVVGDQMLTDVYGGNRLGLYTVLVLPISVKDEGIG 137
                 +     + +  +        V     L        +           +      
Sbjct: 91  SAQHFHTAVHNEEQLAALEEASLDEPVTVWMKLDTGMHRLGVRPEQAEAFYHRLTQCKNV 150

Query: 138 TRINRRVE 145
            +    V 
Sbjct: 151 RQPVNIVS 158


>alr3507 [R] COG2179 Predicted hydrolase of the HAD superfamily
          Length = 359

 Score = 75.9 bits (185), Expect = 2e-14,   Method: Compositional matrix adjust.
 Identities = 13/125 (10%), Positives = 25/125 (20%), Gaps = 1/125 (0%)

Query: 3   TVFDIALEELYALGYRGIITDLDNTLVGAKAPLATPELLLWFAKVKELGFKLIIVSNNNM 62
            V  +              T  D    G         L         L  +    + +  
Sbjct: 29  MVAVVKANAYGHGLLETARTLPDADAFGVARLEEALRLRAGGITKPVLLLEGFFDARDLP 88

Query: 63  D-RVSRFATPLNIEFVHQARKPSNTPFLKAMKQMGLTPEQTIVVGDQMLTDVYGGNRLGL 121
                 F T ++ E    A + ++      +     T    + V  +     Y       
Sbjct: 89  TISAQHFHTAVHNEEQLAALEEASLDEPVTVWMKLDTGMHRLGVRPEQAEAFYHRLTQCK 148

Query: 122 YTVLV 126
                
Sbjct: 149 NVRQP 153


>STM0171 [P] COG0288 Carbonic anhydrase
          Length = 220

 Score = 70.1 bits (170), Expect = 1e-12,   Method: Compositional matrix adjust.
 Identities = 7/156 (4%), Positives = 30/156 (19%), Gaps = 13/156 (8%)

Query: 1   VNTVFDIALEELYALGYRGIITDLDNTLV---GAKAPLATPELLLWFAKVKELGFKLIIV 57
                +    ++      G    L               +         ++       + 
Sbjct: 6   TLISNNALWSKMLVEEDPGFFEKLAQAQKPRFLWIGCSDSRVPAERLTGLE----PGELF 61

Query: 58  SNNNMDRVSRFATPLNIEFVHQARKPSNTPFLKAMKQMGLTPEQTIVVGDQMLTDVYGGN 117
            + N+  +      ++ +    +        L+    +         +   +     G  
Sbjct: 62  VHRNVANLV-----IHTDLNCLSVVQYAVDVLEVEHIIICGHSGCGGIKAAVENPELGLI 116

Query: 118 RLGLYTVLVLPISVKDEGIGTRINRRVERIATTRLR 153
              L  +  + +      +G     +          
Sbjct: 117 NNWLLHIRDIWLKHS-SLLGKMPEEQRLDALYELNV 151


>PH1655 [R] COG1011 Predicted hydrolase (HAD superfamily)
          Length = 241

 Score = 52.8 bits (125), Expect = 3e-07,   Method: Compositional matrix adjust.
 Identities = 28/88 (31%), Positives = 51/88 (57%), Gaps = 9/88 (10%)

Query: 46  KVKELGFKLIIVSNNN----MDRVSR-----FATPLNIEFVHQARKPSNTPFLKAMKQMG 96
           ++KELG++L I+++ N     +++ R     F   + I      +KP    F KA+K   
Sbjct: 105 RLKELGYELGIITDGNPVKQWEKILRLELDDFFEHVIISDFEGVKKPHPKIFKKALKAFN 164

Query: 97  LTPEQTIVVGDQMLTDVYGGNRLGLYTV 124
           + PE+ ++VGD++ +D+YG  R+G+ TV
Sbjct: 165 VKPEEALMVGDRLYSDIYGAKRVGMKTV 192


  Database: COG
    Posted date:  Aug 3, 2010  9:58 AM
  Number of letters in database: 38,378,431
  Number of sequences in database:  115,334
  
Lambda     K      H
   0.320    0.139    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 115334
Number of Hits to DB: 12,231,243
Number of extensions: 472625
Number of successful extensions: 1181
Number of sequences better than 1.0e-05: 4
Number of HSP's gapped: 1180
Number of HSP's successfully gapped: 4
Length of query: 165
Length of database: 38,378,431
Length adjustment: 98
Effective length of query: 67
Effective length of database: 27,075,699
Effective search space: 1814071833
Effective search space used: 1814071833
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 112 (47.8 bits)