BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0545.0006.p (195 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value L106374 [H] COG1057 Nicotinic acid mononucleotide adenylyltransf... 147 1e-35 CAC1262 [H] COG1057 Nicotinic acid mononucleotide adenylyltransf... 127 9e-30 all5063 [H] COG1057 Nicotinic acid mononucleotide adenylyltransf... 118 4e-27 PA4006 [H] COG1057 Nicotinic acid mononucleotide adenylyltransfe... 111 6e-25 L26400 [H] COG1057 Nicotinic acid mononucleotide adenylyltransfe... 95 6e-20 >L106374 [H] COG1057 Nicotinic acid mononucleotide adenylyltransferase Length = 195 Score = 147 bits (371), Expect = 1e-35, Method: Compositional matrix adjust. Identities = 73/191 (38%), Positives = 116/191 (60%), Gaps = 8/191 (4%) Query: 1 MGGTFDPLHIGHMMAAETARESYALEEVWFMPSHIPPHKHEAGA-SGEERLAMVEGAVRN 59 +GG F+P+H H+M A+ + L++V MP +IPPH E S + R+ M+E A++ Sbjct: 12 LGGNFNPIHHAHLMMADQVAQQMNLDKVLLMPENIPPHVDEKETISAKHRVKMLELAIKE 71 Query: 60 HAAFGILDLEIARGGVSYTFETITMLQEEYPEHEFFFIVGADMVQYLPKWHGIEELVRRL 119 + G+ +EI RGG SY+++T+ +L E P+ +++FI+G+DMV+YLPKW+ I+EL++ + Sbjct: 72 NPRLGLELIEIERGGKSYSYDTLKLLTEANPDTDYYFIIGSDMVEYLPKWYKIDELLKLV 131 Query: 120 TFIGVGRPGTPLDLAALPGFIAEKVLLADMPLVDISSTMLRARAAEGKSIRYMVPDAVYD 179 TFI + R T + + P V D PL+ ISSTMLR A+ Y +P V D Sbjct: 132 TFIALRRKDT-ISKSPYP------VTWLDAPLLPISSTMLREMFAKNIEPTYFLPQNVID 184 Query: 180 YVQRSGLYGTQ 190 Y++ LY + Sbjct: 185 YIKTEKLYKKR 195 >CAC1262 [H] COG1057 Nicotinic acid mononucleotide adenylyltransferase Length = 200 Score = 127 bits (320), Expect = 9e-30, Method: Compositional matrix adjust. Identities = 65/193 (33%), Positives = 107/193 (55%), Gaps = 6/193 (3%) Query: 1 MGGTFDPLHIGHMMAAETARESYALEEVWFMPSHIPPHKHEAG-ASGEERLAMVEGAVRN 59 GGTF+P+H H+ A + E L+E+ F+PS PPHK E G A E R MV+ A+++ Sbjct: 7 FGGTFNPIHNAHLNIAAKSIEKLQLDELIFVPSGNPPHKSEKGIAPAELRYEMVKEAIKD 66 Query: 60 HAAFGILDLEIARGGVSYTFETITMLQEEYPEHEFFFIVGADMVQYLPKWHGIEELVRRL 119 + F I D EI + G+SYT+ET+ + ++FFI G D + L KW + ++ Sbjct: 67 NCKFRIDDYEIKKKGISYTYETLEHFSRSQKDVDWFFIAGLDSLMDLDKWRNVNTILSLC 126 Query: 120 TFIGVGRPG-TPLDLAALPGFIAEK----VLLADMPLVDISSTMLRARAAEGKSIRYMVP 174 FI R G + ++ +K ++ D+ +DISST++R + E + I +VP Sbjct: 127 KFIVFNRSGYNKSQVLEQKEYLEKKYINNIVFLDIKPIDISSTIIRQKIRENEYIGDLVP 186 Query: 175 DAVYDYVQRSGLY 187 + +YD ++++ LY Sbjct: 187 EKIYDIIKKNKLY 199 >all5063 [H] COG1057 Nicotinic acid mononucleotide adenylyltransferase Length = 208 Score = 118 bits (296), Expect = 4e-27, Method: Compositional matrix adjust. Identities = 70/200 (35%), Positives = 109/200 (54%), Gaps = 16/200 (8%) Query: 2 GGTFDPLHIGHMMAAETARESYALEEVWFMPSHIPPHKHEAGASGEERLAMVEGAVRNHA 61 GGTFDP+H GH++ AE A + +E+V ++PS PPHK ++ RLAM++ A +++ Sbjct: 8 GGTFDPIHWGHLLIAEAALQQIPIEKVIWVPSLNPPHK--KASAFRHRLAMLQLATQDNP 65 Query: 62 AFGILDLEIARGGVSYTFETITMLQEEYPEHEFFFIVGADMVQYLPKWHGIEELVRRLTF 121 AF + +E R GVSY T+T L +P +++IVG D Q LP+W+ +EL + Sbjct: 66 AFTVSSVEKNRSGVSYAINTLTDLSVCFPNTHWYWIVGLDTFQTLPRWYRGQELAPMCDW 125 Query: 122 IGVGRPGTPLDLAALPGFIAEKVL-------------LADMPLVDISSTMLRARAAEGKS 168 + R ++A I ++V L +PLV +SS+++R GKS Sbjct: 126 LIAPRLVGGENIAQ-SELICKQVKQQLRKQSDTIHWHLLHIPLVGVSSSLIRKLYRIGKS 184 Query: 169 IRYMVPDAVYDYVQRSGLYG 188 IRY+VP+ V Y+ LY Sbjct: 185 IRYLVPEDVRSYIAAHKLYS 204 >PA4006 [H] COG1057 Nicotinic acid mononucleotide adenylyltransferase Length = 214 Score = 111 bits (278), Expect = 6e-25, Method: Compositional matrix adjust. Identities = 68/203 (33%), Positives = 103/203 (50%), Gaps = 18/203 (8%) Query: 2 GGTFDPLHIGHMMAAETARESYALEEVWFMPSHIPPHKHEAGASGEERLAMVEGAVRNHA 61 GGTFDP+HIGHM +A E +AL+E+ +P+ PPH+ S +RLAMVE AV Sbjct: 9 GGTFDPVHIGHMRSAVEMAEQFALDELRLLPNARPPHRETPQVSAAQRLAMVERAVAGVE 68 Query: 62 AFGILDLEIARGGVSYTFETITMLQEEY-PEHEFFFIVGADMVQYLPKWHGIEELVRRLT 120 + E+ R SYT +T+ ++ E + + F ++G D LP WH E L+ Sbjct: 69 RLTVDPRELQRDKPSYTIDTLESVRAELAADDQLFMLIGWDAFCGLPTWHRWEALLDHCH 128 Query: 121 FIGVGRPG----------------TPLDLAALPGFIAEKVLLADMPLVDISSTMLRARAA 164 + + RP + D AL G + + PL +S+T +RA Sbjct: 129 IVVLQRPDADSEPPESLRDLLAARSVADPQALKGPGGQITFVWQTPLA-VSATQIRALLG 187 Query: 165 EGKSIRYMVPDAVYDYVQRSGLY 187 G+S+R++VPDAV +Y++ LY Sbjct: 188 AGRSVRFLVPDAVLNYIEAHHLY 210 >L26400 [H] COG1057 Nicotinic acid mononucleotide adenylyltransferase Length = 311 Score = 95.1 bits (235), Expect = 6e-20, Method: Compositional matrix adjust. Identities = 6/189 (3%), Positives = 39/189 (20%), Gaps = 24/189 (12%) Query: 3 GTFDPLHIGHMMAAETARESYALEEVWFMPSHIPPHKHEAGASGEERLAMVEGAVRNHAA 62 T + +G ++ + + A + + E +++ Sbjct: 30 VTITLVLVGLFLSVILNTSKISNGIENNVRIV---------AYMKLDVHDQETKIQDPKD 80 Query: 63 FGILDLEIARGGVSYTFETITMLQEEYPEHEFFFIVGADMVQYLPKWHGIEELVRRLTFI 122 + + + + ++ + + + Sbjct: 81 NKKTINNPDHLKIYDSIKKVPNVKTVEFSSKEAQLKELTKALGNNWNLFKGDANPLYDAY 140 Query: 123 GVGRP----GTPLDLAALPGFIAEKVLLADMPLVDISSTMLRARAAEGKSIRYMVPDAVY 178 V + ++ + ++ ++ A + + + Sbjct: 141 IVEADKPANVK-----------SVTSKISKLSGIEKATYGGANTAKLFQIAQGIRTWGTA 189 Query: 179 DYVQRSGLY 187 + + Sbjct: 190 AAILLIFVA 198 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.321 0.138 0.415 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 15,578,714 Number of extensions: 664681 Number of successful extensions: 1113 Number of sequences better than 1.0e-05: 7 Number of HSP's gapped: 1103 Number of HSP's successfully gapped: 7 Length of query: 195 Length of database: 38,378,431 Length adjustment: 101 Effective length of query: 94 Effective length of database: 26,729,697 Effective search space: 2512591518 Effective search space used: 2512591518 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.9 bits) S2: 113 (48.1 bits)