BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0544.0044.p (290 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value cynR [K] COG0583 Transcriptional regulator 147 2e-35 BH2102 [K] COG0583 Transcriptional regulator 114 2e-25 BS_gltC [K] COG0583 Transcriptional regulator 107 2e-23 lin1846 [K] COG0583 Transcriptional regulator 103 4e-22 XF1532 [K] COG0583 Transcriptional regulator 99 8e-21 >cynR [K] COG0583 Transcriptional regulator Length = 299 Score = 147 bits (370), Expect = 2e-35, Method: Compositional matrix adjust. Identities = 84/241 (34%), Positives = 128/241 (53%), Gaps = 2/241 (0%) Query: 2 YFMAVFEHLHFTKAAEVLGISQPTLSQQIRLLEADFGIPLFDRIGKKVIVTEAGKLLHQY 61 YF+AV EH FT+AA L +SQP LSQQIR LE G+PLFDR G+ + +T+AG++ QY Sbjct: 8 YFLAVAEHGSFTRAASALHVSQPALSQQIRQLEESLGVPLFDRSGRTIRLTDAGEVWRQY 67 Query: 62 GMKMLQAEMDAKNAIRELRSEKRGTVRLAVLPSDLDFRLVPLFIEFKTQYPET--QLQVF 119 + LQ K AI ++ RG++R+AV P+ + + PL +F +YP QLQ Sbjct: 68 ASRALQELGAGKRAIHDVADLTRGSLRIAVTPTFTSYFIGPLMADFYARYPSITLQLQEM 127 Query: 120 STIFVRDEVLAHKVDIGIGLCSPLDKRLVQVPLGSEPYYLFVHTASELAKRDEITLEEIK 179 S + D + ++D+GI L +PL +E L V LA +++ L + Sbjct: 128 SQEKIEDMLCRDELDVGIAFAPVHSPELEAIPLLTESLALVVAQHHPLAVHEQVALSRLH 187 Query: 180 QHSLVMYPKGYLGRDLVDEVCRKQGFELPTVMEVDSASSLLQLVSAGVGVTIQPRDLLKQ 239 LV+ + R+ +D C K G V+E +S S++L+L+ T+ P + Q Sbjct: 188 DEKLVLLSAEFATREQIDHYCEKAGLHPQVVIEANSISAVLELIRRTSLSTLLPAAIATQ 247 Query: 240 H 240 H Sbjct: 248 H 248 >BH2102 [K] COG0583 Transcriptional regulator Length = 301 Score = 114 bits (284), Expect = 2e-25, Method: Compositional matrix adjust. Identities = 84/287 (29%), Positives = 139/287 (48%), Gaps = 4/287 (1%) Query: 2 YFMAVFEHLHFTKAAEVLGISQPTLSQQIRLLEADFGIPLFDRIGKKVIVTEAGKLLHQY 61 YFM V + H T+AA L ++Q +S+QI LE + G+ LF R G++V +T GK+ + Sbjct: 8 YFMEVAKREHVTEAAAALHVAQSAVSRQIFNLENELGVDLFIRDGRRVKLTPIGKMFLER 67 Query: 62 GMKMLQAEMDAKNAIRELRSEKRGTVRLAVLPSDLDFRLVPLFIEFKTQYPETQLQVFST 121 + DAK ++E ++GT+R+A S + L + F+ +YPE + Q+ Sbjct: 68 ITHAMNVIDDAKREVQEYLDPEKGTIRVAFPISLAAYTLPTVIYAFRKRYPEAKFQLKQA 127 Query: 122 IFVRDEVLAHKVDIGIGLCSPL---DKRLVQVPLGSEPYYLFVHTASELAKRDEITLEEI 178 ++ K D + L P+ +K++ + L +E + LA+ + I L ++ Sbjct: 128 LYHELINGVIKGDYNMALIGPVPMDEKKIARKILFTEQVVALLPLHHPLAENNAIHLRDL 187 Query: 179 KQHSLVMYPKGYLGRDLVDEVCRKQGFELPTVMEVDSASSLLQLVSAGVGVTIQPRDLLK 238 K V+ P+G++ RD+V C GF E D +L LVSAG+GVT+ P L Sbjct: 188 KDDPFVLLPEGFVFRDIVINACSDLGFYPNIAFEGDDIDALKGLVSAGLGVTLMPEVTLV 247 Query: 239 QHLEWSNIVSIPISEPAPIRHLELTYYADRFISKAQQKLSERLINFF 285 S V IP+ EP R + + +R + ++ L FF Sbjct: 248 DSTPRST-VKIPLIEPNVTRTVGVITPTERGLLPTEELFYAFLEEFF 293 >BS_gltC [K] COG0583 Transcriptional regulator Length = 300 Score = 107 bits (267), Expect = 2e-23, Method: Compositional matrix adjust. Identities = 87/293 (29%), Positives = 145/293 (49%), Gaps = 16/293 (5%) Query: 2 YFMAVFEHLHFTKAAEVLGISQPTLSQQIRLLEADFGIPLFDRIGKKVIVTEAGK--LLH 59 YFM V E H ++AA+ L ++Q +S+QI LE + + LF+R G+ + +T GK L+H Sbjct: 8 YFMEVAEREHVSEAADHLHVAQSAISRQIANLEEELNVTLFEREGRNIKLTPIGKEFLIH 67 Query: 60 -QYGMKMLQAEMDAKNAIRELRSEKRGTVRLAVLPSDLDFRLVPLFIE-FKTQYPETQ-- 115 + MK + AK I E RGTV++ P+ L +L+P I FK +YP + Sbjct: 68 VKTAMKAIDY---AKEQIDEYLDPHRGTVKIG-FPTSLASQLLPTVISAFKEEYPHVEFL 123 Query: 116 LQVFSTIFVRDEVLAHKVDIGIGLCSPLDKRLVQVP---LGSEPYYLFVHTASELAKRDE 172 L+ S F+ + V DI + L P+ + L +E Y V LAK+ Sbjct: 124 LRQGSYKFLIEAV--RNRDIDLALLGPVPTNFSDITGKILFTEKIYALVPLNHPLAKQKT 181 Query: 173 ITLEEIKQHSLVMYPKGYLGRDLVDEVCRKQGFELPTVMEVDSASSLLQLVSAGVGVTIQ 232 + L +++ V++P+G++ R++ + C++ GF E + ++ LVSAG+GVT+ Sbjct: 182 VHLIDLRNDQFVLFPEGFVLREMAIDTCKQAGFAPLVSTEGEDLDAIKGLVSAGMGVTLL 241 Query: 233 PRDLLKQHLEWSNIVSIPISEPAPIRHLELTYYADRFISKAQQKLSERLINFF 285 P + V IPI P R + + +R ++ + E +I FF Sbjct: 242 PESTFAETTPRFT-VKIPIEFPQVKRTVGIIKPKNRELAPSANDFYEFVIQFF 293 >lin1846 [K] COG0583 Transcriptional regulator Length = 295 Score = 103 bits (256), Expect = 4e-22, Method: Compositional matrix adjust. Identities = 81/291 (27%), Positives = 141/291 (48%), Gaps = 8/291 (2%) Query: 2 YFMAVFEHLHFTKAAEVLGISQPTLSQQIRLLEADFGIPLFDRIGKKVIVTEAGKLLHQY 61 YFM V H TKA+E L ++Q +S+QI LE + G+PLFDR+G+ + +T G+ Sbjct: 8 YFMEVARVEHMTKASENLHVAQSAVSRQITKLEEELGVPLFDRVGRNMQLTSVGQDFLSQ 67 Query: 62 GMKMLQAEMDAKNAIRELRSEKRGTVRLAVLPSDLDFRLVPLFIE-FKTQYPETQLQVF- 119 L A+ + E +GTVR+ LP+ L +++P I F+ +YPE Q Sbjct: 68 ATIALNELQKAEALVTEYTDPTKGTVRVG-LPNSLSTKVLPSVISTFREKYPEITYQFME 126 Query: 120 STIFVRDEVLAHKVDIGIGLCSPLDKRLVQVP---LGSEPYYLFVHTASELAKRDEITLE 176 T E+L + V + + SP+ + Q+ E L V T+ LA+ ++L+ Sbjct: 127 GTNEELTEMLVNGV-LDMTFLSPVPESSEQIEALRFFDEKLKLIVPTSHHLAENFTVSLK 185 Query: 177 EIKQHSLVMYPKGYLGRDLVDEVCRKQGFELPTVMEVDSASSLLQLVSAGVGVTIQPRDL 236 E+ V+YP+ + +V + K+GFE + ++ LV AG+G++I P + Sbjct: 186 ELSSEKFVLYPEDFDLYKIVTKAANKKGFEPQIAFQSRDFYTIQGLVGAGLGISILPEMI 245 Query: 237 LKQHLEWSNIVSIPISEPAPIRHLELTYYADRFISKAQQKLSERLINFFQS 287 L + + SI + + R + + R +S ++ +I+FF + Sbjct: 246 LDGAI-FKETKSIALRDKELRRSVGIITTKKRNLSPSENLFRSFIISFFSN 295 >XF1532 [K] COG0583 Transcriptional regulator Length = 325 Score = 99.0 bits (245), Expect = 8e-21, Method: Compositional matrix adjust. Identities = 72/236 (30%), Positives = 119/236 (50%), Gaps = 6/236 (2%) Query: 2 YFMAVFEHLHFTKAAEVLGISQPTLSQQIRLLEADFGIPLFDRIGKKVIVTEAGKLLHQY 61 Y +A+ ++ HF +AA +SQPTLS QI+ LE + G+ L +R +KV++T AG+ Sbjct: 22 YLIALADYKHFGRAATACFVSQPTLSTQIKKLEGELGVSLVERAPRKVMMTPAGREAAIR 81 Query: 62 GMKMLQAEMDAKNAIRELRSEKRGTVRLAVLPSDLDFRLVPLFIEFKTQYPETQLQVFST 121 ++ + K A R R + G VRL + P+ + L + + ++P QL++ Sbjct: 82 ARSIVAEVEEMKEAARRSRDPEAGAVRLGIFPTLGPYLLPHVVPSIRYRFP--QLELLLV 139 Query: 122 IFVRDEVLAH----KVDIGIGLCSPLDKRLVQVPLGSEPYYLFVHTASELAKRDEITLEE 177 DE+LA K+D + D++L L EP+ L V LA R E+T+EE Sbjct: 140 EEKSDELLAQLREGKLDAALLALPLHDEQLHTEFLFEEPFVLAVPEGHPLATRREMTMEE 199 Query: 178 IKQHSLVMYPKGYLGRDLVDEVCRKQGFELPTVMEVDSASSLLQLVSAGVGVTIQP 233 + L++ G+ R+ +VC G + + S +L Q+V A VG+T+ P Sbjct: 200 LADERLLLLQDGHCLREQALDVCHMTGASEKSEFQATSLETLRQMVVANVGITLLP 255 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.323 0.139 0.393 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 20,489,699 Number of extensions: 767972 Number of successful extensions: 7157 Number of sequences better than 1.0e-05: 1513 Number of HSP's gapped: 5685 Number of HSP's successfully gapped: 1513 Length of query: 290 Length of database: 38,378,431 Length adjustment: 105 Effective length of query: 185 Effective length of database: 26,268,361 Effective search space: 4859646785 Effective search space used: 4859646785 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.9 bits) S2: 115 (48.9 bits)