BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0544.0006.p (485 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value BH2398 [R] COG0595 Predicted hydrolase of the metallo-beta-lacta... 596 e-170 BS_ykqC [R] COG0595 Predicted hydrolase of the metallo-beta-lact... 553 e-157 BH2662 [R] COG0595 Predicted hydrolase of the metallo-beta-lacta... 548 e-156 lin1026 [R] COG0595 Predicted hydrolase of the metallo-beta-lact... 532 e-151 SA0940 [R] COG0595 Predicted hydrolase of the metallo-beta-lacta... 501 e-141 >BH2398 [R] COG0595 Predicted hydrolase of the metallo-beta-lactamase superfamily Length = 252 Score = 596 bits (1537), Expect = e-170, Method: Compositional matrix adjust. Identities = 0/485 (0%), Positives = 0/485 (0%), Gaps = 1/485 (0%) Query: 1 VTHGHEDHIGGIPYFLKQLNIPVYASRLTLGLIQTKLKEHGLLRQTQLNCIDTESTLNFG 60 + + Q + L L + Sbjct: 72 RSALPDCQFVEADIRNWQPVQALDLIFANASLQWLPDHYELFPHLVSLLNPQGVLAVQMP 131 Query: 61 SITITFFRTNHSIPDCLGIVFDTPEGTVVHTGDFKFDMTPVNKQYPDIHKMAAIGEKGVK 120 + D + + ++ + + Sbjct: 132 DNWLEPTHVLMREVAWEQNYPDRGREPLAGVHAYYDILSEAGCEVDIWRTTYYHQMPSHQ 191 Query: 121 FLLSESTNAERPGFTPSERLVGAHLEEAFHKAENRIFISTFASNVHRLQQIVDAAGHTGR 180 ++ T + L + + L Sbjct: 192 AIIDWVTATGLRPWLQDLTESEQQLFLKRYHQMLEEQYPLQENGQILLAFPRLFIVARRM 251 Query: 181 KLALLGRSMVNVVGVAQELGYLNIPEGMLVEPAEAGKMDRGRIAVLCTGSQGEPMAALSR 240 Sbjct: 252 311 Query: 241 LANSSHRQLEISEGDTVLLAANPIPGNERNVSRIVDNLYMLGARVIYGSRSELHVSGHGS 300 Sbjct: 312 - 370 Query: 301 QEELKLMLTLMKPEYFIPIHGEYRMLHHHSMLAEAVGVKNENIFILKNGDIVESNAGDVR 360 Sbjct: 371 430 Query: 361 QSGRITAGQIYVDGLGIGDIGNVVLRDRRQLSADGILITVITLSQNDGRILNDPDTISRG 420 Sbjct: 431 490 Query: 421 FVYVRNSDTLMEEINQLITSTLQKMSAADLGQWNIIKETIKETLGKFLYERTKRRPMILP 480 Sbjct: 491 550 Query: 481 IIIEV 485 Sbjct: 551 555 >BS_ykqC [R] COG0595 Predicted hydrolase of the metallo-beta-lactamase superfamily Length = 252 Score = 553 bits (1424), Expect = e-157, Method: Compositional matrix adjust. Identities = 0/485 (0%), Positives = 0/485 (0%), Gaps = 1/485 (0%) Query: 1 VTHGHEDHIGGIPYFLKQLNIPVYASRLTLGLIQTKLKEHGLLRQTQLNCIDTESTLNFG 60 + + Q + L L + Sbjct: 72 RSALPDCQFVEADIRNWQPVQALDLIFANASLQWLPDHYELFPHLVSLLNPQGVLAVQMP 131 Query: 61 SITITFFRTNHSIPDCLGIVFDTPEGTVVHTGDFKFDMTPVNKQYPDIHKMAAIGEKGVK 120 + D + + ++ + DI + + Sbjct: 132 DNWLEPTHVLMREVAWEQNYPDRGREPLAGVHAYYDILSEAGCE-VDIWRTTYYHQMPSH 190 Query: 121 FLLSESTNAERPGFTPSERLVGAHLEEAFHKAENRIFISTFASNVHRLQQIVDAAGHTGR 180 + + A + + N L R Sbjct: 191 QAIIDWVTATGLRPWLQDLTESEQQLFLKRYHQMLEEQYPLQENGQILLAFPRLFIVARR 250 Query: 181 KLALLGRSMVNVVGVAQELGYLNIPEGMLVEPAEAGKMDRGRIAVLCTGSQGEPMAALSR 240 Sbjct: 251 310 Query: 241 LANSSHRQLEISEGDTVLLAANPIPGNERNVSRIVDNLYMLGARVIYGSRSELHVSGHGS 300 Sbjct: 311 370 Query: 301 QEELKLMLTLMKPEYFIPIHGEYRMLHHHSMLAEAVGVKNENIFILKNGDIVESNAGDVR 360 Sbjct: 371 430 Query: 361 QSGRITAGQIYVDGLGIGDIGNVVLRDRRQLSADGILITVITLSQNDGRILNDPDTISRG 420 Sbjct: 431 490 Query: 421 FVYVRNSDTLMEEINQLITSTLQKMSAADLGQWNIIKETIKETLGKFLYERTKRRPMILP 480 Sbjct: 491 550 Query: 481 IIIEV 485 Sbjct: 551 555 >BH2662 [R] COG0595 Predicted hydrolase of the metallo-beta-lactamase superfamily Length = 252 Score = 548 bits (1412), Expect = e-156, Method: Compositional matrix adjust. Identities = 0/485 (0%), Positives = 0/485 (0%), Gaps = 1/485 (0%) Query: 1 VTHGHEDHIGGIPYFLKQLNIPVYASRLTLGLIQTKLKEHGLLRQTQLNCIDTESTLNFG 60 + + Q + L L + Sbjct: 72 RSALPDCQFVEADIRNWQPVQALDLIFANASLQWLPDHYELFPHLVSLLNPQGVLAVQMP 131 Query: 61 SITITFFRTNHSIPDCLGIVFDTPEGTVVHTGDFKFDMTPVNKQYPDIHKMAAIGEKGVK 120 + D + + ++ + DI + + Sbjct: 132 DNWLEPTHVLMREVAWEQNYPDRGREPLAGVHAYYDILSEAGCE-VDIWRTTYYHQMPSH 190 Query: 121 FLLSESTNAERPGFTPSERLVGAHLEEAFHKAENRIFISTFASNVHRLQQIVDAAGHTGR 180 + + A + + N L R Sbjct: 191 QAIIDWVTATGLRPWLQDLTESEQQLFLKRYHQMLEEQYPLQENGQILLAFPRLFIVARR 250 Query: 181 KLALLGRSMVNVVGVAQELGYLNIPEGMLVEPAEAGKMDRGRIAVLCTGSQGEPMAALSR 240 Sbjct: 251 310 Query: 241 LANSSHRQLEISEGDTVLLAANPIPGNERNVSRIVDNLYMLGARVIYGSRSELHVSGHGS 300 Sbjct: 311 370 Query: 301 QEELKLMLTLMKPEYFIPIHGEYRMLHHHSMLAEAVGVKNENIFILKNGDIVESNAGDVR 360 Sbjct: 371 430 Query: 361 QSGRITAGQIYVDGLGIGDIGNVVLRDRRQLSADGILITVITLSQNDGRILNDPDTISRG 420 Sbjct: 431 490 Query: 421 FVYVRNSDTLMEEINQLITSTLQKMSAADLGQWNIIKETIKETLGKFLYERTKRRPMILP 480 Sbjct: 491 550 Query: 481 IIIEV 485 Sbjct: 551 555 >lin1026 [R] COG0595 Predicted hydrolase of the metallo-beta-lactamase superfamily Length = 252 Score = 532 bits (1371), Expect = e-151, Method: Compositional matrix adjust. Identities = 0/485 (0%), Positives = 0/485 (0%), Gaps = 1/485 (0%) Query: 1 VTHGHEDHIGGIPYFLKQLNIPVYASRLTLGLIQTKLKEHGLLRQTQLNCIDTESTLNFG 60 + + Q + L L + Sbjct: 72 RSALPDCQFVEADIRNWQPVQALDLIFANASLQWLPDHYELFPHLVSLLNPQGVLAVQMP 131 Query: 61 SITITFFRTNHSIPDCLGIVFDTPEGTVVHTGDFKFDMTPVNKQYPDIHKMAAIGEKGVK 120 + D + + ++ + DI + + Sbjct: 132 DNWLEPTHVLMREVAWEQNYPDRGREPLAGVHAYYDILSEAGCE-VDIWRTTYYHQMPSH 190 Query: 121 FLLSESTNAERPGFTPSERLVGAHLEEAFHKAENRIFISTFASNVHRLQQIVDAAGHTGR 180 + + A + + N L R Sbjct: 191 QAIIDWVTATGLRPWLQDLTESEQQLFLKRYHQMLEEQYPLQENGQILLAFPRLFIVARR 250 Query: 181 KLALLGRSMVNVVGVAQELGYLNIPEGMLVEPAEAGKMDRGRIAVLCTGSQGEPMAALSR 240 Sbjct: 251 310 Query: 241 LANSSHRQLEISEGDTVLLAANPIPGNERNVSRIVDNLYMLGARVIYGSRSELHVSGHGS 300 Sbjct: 311 370 Query: 301 QEELKLMLTLMKPEYFIPIHGEYRMLHHHSMLAEAVGVKNENIFILKNGDIVESNAGDVR 360 Sbjct: 371 430 Query: 361 QSGRITAGQIYVDGLGIGDIGNVVLRDRRQLSADGILITVITLSQNDGRILNDPDTISRG 420 Sbjct: 431 490 Query: 421 FVYVRNSDTLMEEINQLITSTLQKMSAADLGQWNIIKETIKETLGKFLYERTKRRPMILP 480 Sbjct: 491 550 Query: 481 IIIEV 485 Sbjct: 551 555 >SA0940 [R] COG0595 Predicted hydrolase of the metallo-beta-lactamase superfamily Length = 252 Score = 501 bits (1289), Expect = e-141, Method: Compositional matrix adjust. Identities = 0/486 (0%), Positives = 0/486 (0%), Gaps = 2/486 (0%) Query: 1 VTHGHEDHIGGIPYFLKQLNIPVYASRLTLGLIQTKLKEHGLLRQTQLNCIDTESTLNFG 60 + + Q + L L + Sbjct: 72 RSALPDCQFVEADIRNWQPVQALDLIFANASLQWLPDHYELFPHLVSLLNPQGVLAVQMP 131 Query: 61 SITITFFRTNHSIPDCLGIVFDTPEGTVVHTGDFKFDMTPVNKQYPDIHKMAAIGEKGVK 120 + D + + ++ + DI + + Sbjct: 132 DNWLEPTHVLMREVAWEQNYPDRGREPLAGVHAYYDILSEAGCE-VDIWRTTYYHQMPSH 190 Query: 121 FLLSESTNAERPGFTPSERLVGAHLEEAFHKAENRIFISTFASNVHRLQQIVDAAGHTGR 180 + + A + + N L R Sbjct: 191 QAIIDWVTATGLRPWLQDLTESEQQLFLKRYHQMLEEQYPLQENGQILLAFPRLFIVARR 250 Query: 181 KLALLGRSMVNVVGVAQELGYLNIPEGMLVEPAEAGKMDRGRIAVLCTGSQGEPMAALSR 240 Sbjct: 251 310 Query: 241 LANSSHRQLEISEGDTVLLAANPIPGNERNVSRIVDNLYMLGARVIYGSRSELHVSGHGS 300 Sbjct: 311 370 Query: 301 QEELKLMLTLMKPEYFIPIHGEYRMLHHHSMLAEAVGVKNENIFILKNGDIVESNAGDVR 360 Sbjct: 371 430 Query: 361 QSGRITAGQIYVDGLGIGDIGNVVLRDRRQLSADGILITVITLSQNDGRILNDPDTISRG 420 Sbjct: 431 490 Query: 421 FVYVRNSDTLMEEINQLI-TSTLQKMSAADLGQWNIIKETIKETLGKFLYERTKRRPMIL 479 Sbjct: 491 550 Query: 480 PIIIEV 485 Sbjct: 551 556 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.319 0.137 0.393 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 35,685,296 Number of extensions: 1542465 Number of successful extensions: 4130 Number of sequences better than 1.0e-05: 26 Number of HSP's gapped: 4059 Number of HSP's successfully gapped: 26 Length of query: 485 Length of database: 38,378,431 Length adjustment: 110 Effective length of query: 375 Effective length of database: 25,691,691 Effective search space: 9634384125 Effective search space used: 9634384125 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 118 (50.1 bits)