BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0541.0084.p (429 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value BMEII0521 [E] COG0665 Glycine/D-amino acid oxidases (deaminating) 94 6e-19 NMA0819 [E] COG0665 Glycine/D-amino acid oxidases (deaminating) 87 8e-17 ZordL [E] COG0665 Glycine/D-amino acid oxidases (deaminating) 77 7e-14 ordL [E] COG0665 Glycine/D-amino acid oxidases (deaminating) 77 7e-14 BMEII0391 [E] COG0665 Glycine/D-amino acid oxidases (deaminating) 74 4e-13 >BMEII0521 [E] COG0665 Glycine/D-amino acid oxidases (deaminating) Length = 539 Score = 93.6 bits (231), Expect = 6e-19, Method: Compositional matrix adjust. Identities = 88/394 (22%), Positives = 153/394 (38%), Gaps = 18/394 (4%) Query: 10 WERTLPHFPVYPVLDGDITCDCLIVGGGMGGAMASYRLSSSGASTVLIDKYAVGKGSTCA 69 +E P P YP LDG D +++GGG G A+Y L+ G VLI+ +G G++ Sbjct: 125 YEANTPDRPQYPELDGSQQADVVVIGGGYTGLSAAYHLAKQGTDVVLIEAARLGDGASGR 184 Query: 70 NTGLLQVTSDKSLTSCMNTFGADNGLLFYKLCRKAMEDILKLPGALDIDPHIIPRSSLLY 129 N G +G + + + +A +L ID + + + Sbjct: 185 NGGQFGTGQRTWAEDLETEYGYERAKALFNVAEEAKSYLLAFAEEHAIDMEYV-QGHISV 243 Query: 130 ASSPEDVTALKLEHEHLAAHGFD---TEFWEEDKIRAHYSFAK-PAAIYSRGDAETNPFR 185 P + + + E +A+ F+ F + + ++ +Y +P + Sbjct: 244 VHKPRYLKSYERHVEQMASR-FNYPHQRFLDRAETAELLGTSRYHGGVYDSATGHIHPMK 302 Query: 186 MLHSLIHKAHASGVRVYEHTKARHFDFGTDGVTCYTESGRIFANHVIFALGYETQEMKKD 245 +L AH +G +++E TKA + V T G I A H A+ ++ Sbjct: 303 LLIGTAKAAHTAGAKLFEDTKATKISTASGRVEVETTRGTIRARHAFIAVNAYGGRLEPV 362 Query: 246 RGAELNYTYAIM--TRPL-KNLPRWHEQSLIWETARPYLYFRTTNDGRIIAGGKDEQLPD 302 + + + + T PL + P + ++ YFR + DGR++ GG++ D Sbjct: 363 SASHVMPIRSFIGATAPLGDDSPVIPGGESVDDSRFVVRYFRRSKDGRLLFGGREAYTAD 422 Query: 303 PGQXXXXXXXXXXXXXXXXXXXFPEIKGAAAEFAWGGVFGTSHDGLPFIGPHPEYPHCYF 362 +P ++ AWGG G + PF+ P Sbjct: 423 ------NPRDISAHIRRQITEIYPALENVEITHAWGGSVGITMPRQPFV--REVMPGVIS 474 Query: 363 IEGYGGNGTVYSMLAAELLADTLAGISRPELELF 396 GY G+G + + +L ADTLAG R +L+LF Sbjct: 475 AGGYSGHGVMLANYVGKLYADTLAG-RREKLKLF 507 >NMA0819 [E] COG0665 Glycine/D-amino acid oxidases (deaminating) Length = 307 Score = 86.7 bits (213), Expect = 8e-17, Method: Compositional matrix adjust. Identities = 0/388 (0%), Positives = 0/388 (0%), Gaps = 31/388 (7%) Query: 15 PHFPVYPVLDGDITCDCLIVGGGMGGAMASYRLSSSGASTVLIDKYAVGKGSTCANTGLL 74 + P + G M + ++ + YA S Sbjct: 20 LA-ELEPGEIVMTDIVEGLPQGKALDLMQAGAINGYDTQVTGTNDYADITDSDLVIIT-- 76 Query: 75 QVTSDKS--LTSCMNTFGADNGLLFYKLCRKAME--DILKLPGALDIDPHIIPRSSLLYA 130 + K + + + + ++ + LD+ + + Sbjct: 77 AGIARKPGMTREDLMKTNSKIIGEVSRNIAEYAPNSIVINVTNPLDVITY---VAMKTTG 133 Query: 131 SSPEDVTALKLEHEHLAAHGFDT--EFWEEDKIRAHY-SFAKPAAIYSRGDAETNPFRML 187 + V + + F + I A + + + Sbjct: 134 FETKKVFGMSGVLDAGRFASFIAEELNCSKKDIEAMVIGGHGDLMVPLPQYTTVSGIPLP 193 Query: 188 HSLIHKAHASGVRVYEHTKARHFDFGTDGVTCYTESGRIFANHVIFAL----GYETQEMK 243 L + A V + A G Y S I + T Sbjct: 194 ELLPEETIARLVERTVNGGAEIVGLLKQGSAFYAPSAAIVSVAEAVLKDSKRILPTSAYL 253 Query: 244 KDRGAELNYTYAIMTRPL----KNLPRWHEQSLIWETARPYLYFRTTNDGRIIAGGKDEQ 299 + + + + ++ + + + Sbjct: 254 EGQYGQEGIYFGVLAKLGANGVEEVLE-- 311 Query: 300 LPDPGQXXXXXXXXXXXXXXXXXXXFPEIKGAAAEFAWGGVFGTSHDGLPFIGPHPEYPH 359 Sbjct: 312 -------- 363 Query: 360 CYFIEGYGGNGTVYSMLAAELLADTLAG 387 Sbjct: 364 391 >ZordL [E] COG0665 Glycine/D-amino acid oxidases (deaminating) Length = 426 Score = 76.6 bits (187), Expect = 7e-14, Method: Compositional matrix adjust. Identities = 85/379 (22%), Positives = 151/379 (39%), Gaps = 24/379 (6%) Query: 20 YPVLDGDITCDCLIVGGGMGGAMASYRLSSSGASTVLIDKYAVGKGSTCANTGLLQVTSD 79 + L+ ITCD +VGGG G ++ L+ +G V+++ +G G++ N G L + Sbjct: 19 FDTLNESITCDVCVVGGGYTGLSSALHLAEAGFDVVVLEASRIGFGASGRNGGQLVNSYS 78 Query: 80 KSLTSCMNTFGADNGLLFYKLCRKAMEDILKLPGALDIDPHIIPRSSLLYASSPEDVTAL 139 + + ++G D + + + E I + ID P L A + + + L Sbjct: 79 RDIDVIEKSYGMDTARMLGSMMFEGGEIIRERIKRYQIDCDYRP-GGLFVAMNDKQLATL 137 Query: 140 KLEHEHLAAHGFDT-EFWEEDKIRAHYSFAK-PAAIYSRGDAETNPFRMLHSLIHKAHAS 197 + + E+ +G E + + IR + + A+ +P + + Sbjct: 138 EEQKENWERYGNKQLELLDANAIRREVASDRYTGALLDHSGGHIHPLNLAIGEADAIRLN 197 Query: 198 GVRVYEHTKARHFDFGTDGVTCYTESGRIFANHVIFA----LGYETQEMKKDRGAELNYT 253 G RVYE + T V T G++ A +VI A LG + + R Sbjct: 198 GGRVYELSAVTQIQHTTPAVV-RTAKGQVTAKYVIVAGNAYLGDKVEPELAKRSMPCGTQ 256 Query: 254 YAIMTRPLKNLPR-WHEQSLIWETARPYL-YFRTTNDGRIIAGGK---DEQLPDPGQXXX 308 R ++L R ++ E L Y+R T D R++ GG + PD + Sbjct: 257 VITTERLSEDLARSLIPKNYCVEDCNYLLDYYRLTADNRLLYGGGVVYGARDPDDVERLV 316 Query: 309 XXXXXXXXXXXXXXXXFPEIKGAAAEFAWGGVFGTSHDGLPFIGPHPEYPHCYFIEGYGG 368 FP++KG ++ W G F + +P G + Y+++GY G Sbjct: 317 VPKLLKT---------FPQLKGVKIDYRWTGNFLLTLSRMPQFGRLD--TNIYYMQGYSG 365 Query: 369 NGTVYSMLAAELLADTLAG 387 +G + LA L+A+ L G Sbjct: 366 HGVTCTHLAGRLIAELLRG 384 >ordL [E] COG0665 Glycine/D-amino acid oxidases (deaminating) Length = 426 Score = 76.6 bits (187), Expect = 7e-14, Method: Compositional matrix adjust. Identities = 85/379 (22%), Positives = 151/379 (39%), Gaps = 24/379 (6%) Query: 20 YPVLDGDITCDCLIVGGGMGGAMASYRLSSSGASTVLIDKYAVGKGSTCANTGLLQVTSD 79 + L+ ITCD +VGGG G ++ L+ +G V+++ +G G++ N G L + Sbjct: 19 FDTLNESITCDVCVVGGGYTGLSSALHLAEAGFDVVVLEASRIGFGASGRNGGQLVNSYS 78 Query: 80 KSLTSCMNTFGADNGLLFYKLCRKAMEDILKLPGALDIDPHIIPRSSLLYASSPEDVTAL 139 + + ++G D + + + E I + ID P L A + + + L Sbjct: 79 RDIDVIEKSYGMDTARMLGSMMFEGGEIIRERIKRYQIDCDYRP-GGLFVAMNDKQLATL 137 Query: 140 KLEHEHLAAHGFDT-EFWEEDKIRAHYSFAK-PAAIYSRGDAETNPFRMLHSLIHKAHAS 197 + + E+ +G E + + IR + + A+ +P + + Sbjct: 138 EEQKENWERYGNKQLELLDANAIRREVASDRYTGALLDHSGGHIHPLNLAIGEADAIRLN 197 Query: 198 GVRVYEHTKARHFDFGTDGVTCYTESGRIFANHVIFA----LGYETQEMKKDRGAELNYT 253 G RVYE + T V T G++ A +VI A LG + + R Sbjct: 198 GGRVYELSAVTQIQHTTPAVV-RTAKGQVTAKYVIVAGNAYLGDKVEPELAKRSMPCGTQ 256 Query: 254 YAIMTRPLKNLPR-WHEQSLIWETARPYL-YFRTTNDGRIIAGGK---DEQLPDPGQXXX 308 R ++L R ++ E L Y+R T D R++ GG + PD + Sbjct: 257 VITTERLSEDLARSLIPKNYCVEDCNYLLDYYRLTADNRLLYGGGVVYGARDPDDVERLV 316 Query: 309 XXXXXXXXXXXXXXXXFPEIKGAAAEFAWGGVFGTSHDGLPFIGPHPEYPHCYFIEGYGG 368 FP++KG ++ W G F + +P G + Y+++GY G Sbjct: 317 VPKLLKT---------FPQLKGVKIDYRWTGNFLLTLSRMPQFGRLD--TNIYYMQGYSG 365 Query: 369 NGTVYSMLAAELLADTLAG 387 +G + LA L+A+ L G Sbjct: 366 HGVTCTHLAGRLIAELLRG 384 >BMEII0391 [E] COG0665 Glycine/D-amino acid oxidases (deaminating) Length = 430 Score = 73.9 bits (180), Expect = 4e-13, Method: Compositional matrix adjust. Identities = 89/393 (22%), Positives = 148/393 (37%), Gaps = 15/393 (3%) Query: 10 WERTLPHFPVYPVLDGDITCDCLIVGGGMGGAMASYRLSSSGASTVLIDKYAVGKGSTCA 69 WE+T P P L GD+ D +IVGGG G + L+ G ++++ +G G + Sbjct: 14 WEKTAPAAPKTTALQGDLAADVVIVGGGFTGLSTALHLAEKGVCAIVLEGIEIGYGGSGR 73 Query: 70 NTGLLQVTSDKSLTSCMNTFGADNGLLFYKLCRKAMEDILKLPGALDIDPHIIPRSSLLY 129 N GL+ G G + A + + ++ I + + +L Sbjct: 74 NVGLVNAGMWVMPDDLPGVLGQKYGDRLLDVLGNAPKLVFEIIEKHKIACEVEKQGTLHC 133 Query: 130 ASSPEDVTALKLEHEHLAAHGFDTEFWEEDKIRAHY-SFAKPAAIYSRGDAETNPFRMLH 188 A + + L+ HE A G + + + + A + A ++ P + Sbjct: 134 AVGQKGLKELEDRHEQWARRGANVKLLDARETEARVGTRAYTGSLLDLRAGTVQPLAYVR 193 Query: 189 SLIHKAHASGVRVYEHTKARHFDFGTDGVTCYTESGRIFANHVIFALGYETQEMKKDRGA 248 L H A A+G V+ + + T G + AN V+ A T + A Sbjct: 194 GLAHAAIAAGATVFTGSPVIGAEEKNGKWVVRTARGSVTANWVVVATNAYTNAPWAEVRA 253 Query: 249 ELNYT--YAIMTRPLK-NLPR--WHEQSLIWETARPYLYFRTTNDGRIIAGGKDEQLPDP 303 EL + + + T+PL NL + E+ +W+T FR GR++ G L + Sbjct: 254 ELVHLPYFNMATKPLSDNLKKSILPERQGVWDTKEVLSSFRFDQQGRLVFGSVG-ALRNT 312 Query: 304 GQXXXXXXXXXXXXXXXXXXXFPEIKGAAAEFAWGGVFGTSHDGLPFIGPHPEYPHCYFI 363 G FP+I E W G G ++D LP H + Sbjct: 313 G-----AAVHKAWAKKSLKRLFPQIGAVEFEAEWYGKIGMTNDSLPKF--HRLARNVVGF 365 Query: 364 EGYGGNGTVYSMLAAELLADTLAG-ISRPELEL 395 GY G G + +LL+ ++G IS +L L Sbjct: 366 SGYNGRGIAPGTVFGKLLSQLVSGEISEADLPL 398 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.321 0.138 0.429 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 31,311,314 Number of extensions: 1325513 Number of successful extensions: 2763 Number of sequences better than 1.0e-05: 26 Number of HSP's gapped: 2732 Number of HSP's successfully gapped: 26 Length of query: 429 Length of database: 38,378,431 Length adjustment: 109 Effective length of query: 320 Effective length of database: 25,807,025 Effective search space: 8258248000 Effective search space used: 8258248000 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 117 (49.7 bits)