BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0541.0023.p (229 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value Rv0981 [TK] COG0745 Response regulators consisting of a CheY-lik... 187 1e-47 MT1009 [TK] COG0745 Response regulators consisting of a CheY-lik... 187 1e-47 ML0174 [TK] COG0745 Response regulators consisting of a CheY-lik... 186 4e-47 sll0396 [TK] COG0745 Response regulators consisting of a CheY-li... 183 2e-46 Cgl0850 [TK] COG0745 Response regulators consisting of a CheY-li... 172 3e-43 >Rv0981 [TK] COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Length = 230 Score = 187 bits (475), Expect = 1e-47, Method: Compositional matrix adjust. Identities = 94/227 (41%), Positives = 130/227 (57%), Gaps = 1/227 (0%) Query: 1 MRPNILIIDDDEKIISMLRRGLAFEGYDVKTATNGADGLRAVLNSXXXXXXXXXXXXXXX 60 M IL++DDD + LRR L+F GY V+ A +G + L + + Sbjct: 1 MSVRILVVDDDRAVRESLRRSLSFNGYSVELAHDGVEALDMIASDRPDALVLDVMMPRLD 60 Query: 61 GFEVCRRLREGGSTVPVLMLTAKDEIEHRVKGLDLGADDYLVKPFXXXXXXXXXXXXXXX 120 G EVCR+LR G +P+L+LTA+D + RV GLD GADDYL KPF Sbjct: 61 GLEVCRQLRGTGDDLPILVLTARDSVSERVAGLDAGADDYLPKPFALEELLARMRALLRR 120 Query: 121 KSEQGGGSSDQAVSYEDITLDVDSREVTRGGKRLELTAKEFELLHLFMQNPKRVLSRDLI 180 + S A+ + D+TLD +REV RG +R+ LT EF LL + + NP+RVL+R I Sbjct: 121 TKPEDAAES-MAMRFSDLTLDPVTREVNRGQRRISLTRTEFALLEMLIANPRRVLTRSRI 179 Query: 181 MDKIWGYDYSGESNVLEVYIAMLRQKTEEHGGKRLIQTIRGAGYILR 227 ++++WG+D+ N LEVY+ LR+KTE G RLI T+RG GY+LR Sbjct: 180 LEEVWGFDFPTSGNALEVYVGYLRRKTEADGEPRLIHTVRGVGYVLR 226 >MT1009 [TK] COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Length = 230 Score = 187 bits (475), Expect = 1e-47, Method: Compositional matrix adjust. Identities = 94/227 (41%), Positives = 130/227 (57%), Gaps = 1/227 (0%) Query: 1 MRPNILIIDDDEKIISMLRRGLAFEGYDVKTATNGADGLRAVLNSXXXXXXXXXXXXXXX 60 M IL++DDD + LRR L+F GY V+ A +G + L + + Sbjct: 1 MSVRILVVDDDRAVRESLRRSLSFNGYSVELAHDGVEALDMIASDRPDALVLDVMMPRLD 60 Query: 61 GFEVCRRLREGGSTVPVLMLTAKDEIEHRVKGLDLGADDYLVKPFXXXXXXXXXXXXXXX 120 G EVCR+LR G +P+L+LTA+D + RV GLD GADDYL KPF Sbjct: 61 GLEVCRQLRGTGDDLPILVLTARDSVSERVAGLDAGADDYLPKPFALEELLARMRALLRR 120 Query: 121 KSEQGGGSSDQAVSYEDITLDVDSREVTRGGKRLELTAKEFELLHLFMQNPKRVLSRDLI 180 + S A+ + D+TLD +REV RG +R+ LT EF LL + + NP+RVL+R I Sbjct: 121 TKPEDAAES-MAMRFSDLTLDPVTREVNRGQRRISLTRTEFALLEMLIANPRRVLTRSRI 179 Query: 181 MDKIWGYDYSGESNVLEVYIAMLRQKTEEHGGKRLIQTIRGAGYILR 227 ++++WG+D+ N LEVY+ LR+KTE G RLI T+RG GY+LR Sbjct: 180 LEEVWGFDFPTSGNALEVYVGYLRRKTEADGEPRLIHTVRGVGYVLR 226 >ML0174 [TK] COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Length = 228 Score = 186 bits (471), Expect = 4e-47, Method: Compositional matrix adjust. Identities = 93/223 (41%), Positives = 129/223 (57%), Gaps = 1/223 (0%) Query: 5 ILIIDDDEKIISMLRRGLAFEGYDVKTATNGADGLRAVLNSXXXXXXXXXXXXXXXGFEV 64 IL +DDD + LRR L+F GY V+ A +G + L V G EV Sbjct: 3 ILAVDDDRAVRESLRRSLSFNGYSVELANDGVEALEMVARDRPDALVLDVMMPRLDGLEV 62 Query: 65 CRRLREGGSTVPVLMLTAKDEIEHRVKGLDLGADDYLVKPFXXXXXXXXXXXXXXXKSEQ 124 CR+LR G +P+L+LTA+D + RV GLD GADDYL KPF +++ Sbjct: 63 CRQLRSTGDDLPILVLTARDSVSERVAGLDAGADDYLPKPFALEELLARIRALLR-RTKP 121 Query: 125 GGGSSDQAVSYEDITLDVDSREVTRGGKRLELTAKEFELLHLFMQNPKRVLSRDLIMDKI 184 + A+S+ D+TLD +REV RG + + LT EF LL + + NP+RVL+R I++++ Sbjct: 122 DDAAESVAMSFSDLTLDPVTREVARGQRWISLTRTEFALLEMLIANPRRVLTRSRILEEV 181 Query: 185 WGYDYSGESNVLEVYIAMLRQKTEEHGGKRLIQTIRGAGYILR 227 WG+D+ N LEVY+ LR+KTE G RLI T+RG GY+LR Sbjct: 182 WGFDFPTSGNALEVYVGYLRRKTEADGESRLIHTVRGVGYVLR 224 >sll0396 [TK] COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Length = 224 Score = 183 bits (464), Expect = 2e-46, Method: Compositional matrix adjust. Identities = 90/227 (39%), Positives = 138/227 (60%), Gaps = 4/227 (1%) Query: 1 MRPNILIIDDDEKIISMLRRGLAFEGYDVKTATNGADGLRAVLNSXXXXXXXXXXXXXXX 60 M +L+++++EK+ + L +EGYDV A +G G Sbjct: 1 MSHRVLVVEEEEKLARFMELELKYEGYDVSVARDGLKGFTQAQEFPPDLIIVNGALPGMS 60 Query: 61 GFEVCRRLREGGSTVPVLMLTAKDEIEHRVKGLDLGADDYLVKPFXXXXXXXXXXXXXXX 120 G E+CRRLRE GS +P++++TAKD++E RV GLD GADDY+VKPF Sbjct: 61 GLELCRRLREMGSRIPIILITAKDDVEERVMGLDAGADDYIVKPFNSDEFFARIRV---- 116 Query: 121 KSEQGGGSSDQAVSYEDITLDVDSREVTRGGKRLELTAKEFELLHLFMQNPKRVLSRDLI 180 + + +SD+ + + D+ + +RE+ RG + ++LTAKEFELL + + ++VL+R+ I Sbjct: 117 QLRRTHTTSDEVLQFADLRFNRSTREIQRGDRLIDLTAKEFELLDYLLSHARQVLTREQI 176 Query: 181 MDKIWGYDYSGESNVLEVYIAMLRQKTEEHGGKRLIQTIRGAGYILR 227 ++++WGYD+ G+SN++EVYI LR K E G RLIQT+RG GY+LR Sbjct: 177 LERVWGYDFMGDSNIIEVYIRYLRLKLEAAGEPRLIQTVRGVGYVLR 223 >Cgl0850 [TK] COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Length = 232 Score = 172 bits (437), Expect = 3e-43, Method: Compositional matrix adjust. Identities = 94/226 (41%), Positives = 129/226 (57%), Gaps = 3/226 (1%) Query: 5 ILIIDDDEKIISMLRRGLAFEGYDVKTATNGADGLRAVLNSXXXXXXXXXXXXXXXGFEV 64 IL++DD++ + LRR L+F GY+V A +G L + G EV Sbjct: 3 ILVVDDEQAVRDSLRRSLSFNGYNVVLAEDGIQALEMIDKEQPALVILDVMMPGMDGLEV 62 Query: 65 CRRLREGGSTVPVLMLTAKDEIEHRVKGLDLGADDYLVKPFXXXXXXXXXXXXXXXKSEQ 124 CR LR G P+L+LTA+D + RV GLD GADDYL KPF + + Sbjct: 63 CRHLRSEGDDRPILILTARDNVSDRVGGLDAGADDYLAKPFALEELLARVRSLVRRSAVE 122 Query: 125 GGGSS--DQAV-SYEDITLDVDSREVTRGGKRLELTAKEFELLHLFMQNPKRVLSRDLIM 181 SS +QA+ S D+TLD +SR+V R G+ + LT EF LL L ++N ++VL+R I+ Sbjct: 123 SNQSSSIEQALLSCGDLTLDPESRDVYRNGRAISLTRTEFALLQLLLKNQRKVLTRAQIL 182 Query: 182 DKIWGYDYSGESNVLEVYIAMLRQKTEEHGGKRLIQTIRGAGYILR 227 +++WG D+ N LEVYI LR+KTE G RLI T+RG GY+LR Sbjct: 183 EEVWGCDFPTSGNALEVYIGYLRRKTELEGEDRLIHTVRGVGYVLR 228 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.318 0.139 0.395 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 14,966,410 Number of extensions: 530121 Number of successful extensions: 2872 Number of sequences better than 1.0e-05: 296 Number of HSP's gapped: 2492 Number of HSP's successfully gapped: 302 Length of query: 229 Length of database: 38,378,431 Length adjustment: 103 Effective length of query: 126 Effective length of database: 26,499,029 Effective search space: 3338877654 Effective search space used: 3338877654 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 114 (48.5 bits)