BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0538.0022.p (313 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value CAC0451 [T] COG0642 Signal transduction histidine kinase 183 4e-46 sll0337 [T] COG0642 Signal transduction histidine kinase 100 2e-21 baeS [T] COG0642 Signal transduction histidine kinase 94 2e-19 ZbaeS [T] COG0642 Signal transduction histidine kinase 94 2e-19 >CAC0451 [T] COG0642 Signal transduction histidine kinase Length = 416 Score = 183 bits (464), Expect = 4e-46, Method: Compositional matrix adjust. Identities = 99/250 (39%), Positives = 154/250 (61%), Gaps = 5/250 (2%) Query: 66 EGELSILHSEITKMTLRIRDQNNALKKEKEHLADSLADIAHQLRTPLTSVNLILSLLANN 125 EGEL L + +M+ I + N LK+EK L + + DI+HQL+TPL+S+ + LL N Sbjct: 162 EGELGKLSASFNRMSSIIENTLNNLKEEKIFLKNMMQDISHQLKTPLSSLKIFNELLLNQ 221 Query: 126 --PDENERKAFVRETEELLVRMDWLITSLLKLSRLDAGIVVFQSVQIDVNHLINAALRPF 183 DE+ F+ E+++ L +M+WLI +LLK++RLDAG + F++ + + + ++ Sbjct: 222 NIKDEDTMDEFLHESKKQLDKMEWLIINLLKMARLDAGAIDFKNEKRSIEETVCESI-SL 280 Query: 184 LIPM-ELHDIDLQIDAPEGMIIQGDSGWLSEAIQNILKNCMESTGENGKIEIVCTDNPLF 242 L PM L + + +++ + + D WL EA NI+KNC+E TG+NG+I+I +P+ Sbjct: 281 LKPMYTLKNQKVSVESTDKAYFKHDKKWLLEAFSNIIKNCIEHTGDNGEIKIHVYRSPIM 340 Query: 243 TEITIHDSGAGFEKEDLPSLFDRFYRGTN-PNATGYGIGLSLCKMIITRQGGTITAKNHP 301 ++TI D+G+G K+DLP +F+RFY+G N + GIGLS+ K II QGG IT K+ Sbjct: 341 VKVTIEDNGSGISKDDLPHIFERFYKGKGVYNKSSTGIGLSMAKSIIENQGGFITVKSAV 400 Query: 302 QGGAIFAIRF 311 G IF I F Sbjct: 401 SAGTIFNIVF 410 >sll0337 [T] COG0642 Signal transduction histidine kinase Length = 430 Score = 100 bits (250), Expect = 2e-21, Method: Compositional matrix adjust. Identities = 70/227 (30%), Positives = 112/227 (49%), Gaps = 20/227 (8%) Query: 100 SLADIAHQLRTPLTSVNLILSLL-----ANNPDENERKAFVRETEELLVRMDWLITSLLK 154 + +D+AH+LRTPLT+V LI L A + D ER ++E + R+ L+ S L Sbjct: 201 AFSDLAHELRTPLTAVALIAERLQARLPAEDGDWAER--LLKE----ISRLQNLVESWLH 254 Query: 155 LSRLDAGIVVF-QSVQIDVNHLINAALRPFLIPMELHDIDLQIDAPEGMIIQGDSGWLSE 213 L+++ A ++ + I++ HL+ + +I L P + ++GD L + Sbjct: 255 LTQITANPNLYLEPEPINLRHLLAITWERLTPIAVVKNITLDYQGPTKLNLEGDGDRLMQ 314 Query: 214 AIQNILKNCMESTGENGKIEIVCTDNPLFTEITIHDSGAGFEKEDLPSLFDRFYRGTNPN 273 + NIL N ++ + G I + + I D G GF+ DLP +F+R YRG + Sbjct: 315 VLMNILDNTLKYSPPEGTIFVQGHQGTEGITMIIRDQGLGFQPRDLPYIFERLYRGDSSR 374 Query: 274 AT--------GYGIGLSLCKMIITRQGGTITAKNHPQGGAIFAIRFP 312 A G G+GL++ K I+ G +TA NH GGA+F I P Sbjct: 375 ARLHPDSQRHGSGLGLAIAKEIVLAHRGNLTAANHETGGAMFTIELP 421 >baeS [T] COG0642 Signal transduction histidine kinase Length = 467 Score = 94.4 bits (233), Expect = 2e-19, Method: Compositional matrix adjust. Identities = 66/245 (26%), Positives = 110/245 (44%), Gaps = 12/245 (4%) Query: 75 EITKMTLRIRDQNNALKKEKEHLADSLADIAHQLRTPLTSVNLILSLLANNPDENERKAF 134 E+ K+ + L+K ++ D +ADI+H+LRTPL + L + ++ + F Sbjct: 219 ELGKLAQDFNQLASTLEKNQQMRRDFMADISHELRTPLAVLRGELEAI-----QDGVRKF 273 Query: 135 VRET----EELLVRMDWLITSLLKLSRLDAGIVVFQSVQIDVNHLINAALRPFLIPMELH 190 ET + + + L+ L +LS D G + +Q +D+ L+ A F Sbjct: 274 TPETVASLQAEVGTLTKLVDDLHQLSMSDEGALAYQKAPVDLIPLLEVAGGAFRERFASR 333 Query: 191 DIDLQIDAPEGMIIQGDSGWLSEAIQNILKNCMESTGENGKIEIVCTDNPLFTEITIHDS 250 + LQ P+ + + GD L + N+L+N + T G ++I +T DS Sbjct: 334 GLKLQFSLPDSITVFGDRDRLMQLFNNLLENSLRYTDSGGSLQISAGQRDKTVRLTFADS 393 Query: 251 GAGFEKEDLPSLFDRFYR---GTNPNATGYGIGLSLCKMIITRQGGTITAKNHPQGGAIF 307 G + L LF+RFYR N + G G+GL++C I+ G I A + P GG Sbjct: 394 APGVSDDQLQKLFERFYRTEGSRNRASGGSGLGLAICLNIVEAHNGRIIAAHSPFGGVSI 453 Query: 308 AIRFP 312 + P Sbjct: 454 TVELP 458 >ZbaeS [T] COG0642 Signal transduction histidine kinase Length = 467 Score = 94.4 bits (233), Expect = 2e-19, Method: Compositional matrix adjust. Identities = 66/245 (26%), Positives = 111/245 (45%), Gaps = 12/245 (4%) Query: 75 EITKMTLRIRDQNNALKKEKEHLADSLADIAHQLRTPLTSVNLILSLLANNPDENERKAF 134 E+ K+ + L+K ++ D +ADI+H+LRTPL + L + ++ + F Sbjct: 219 ELGKLAQDFNQLASTLEKNQQMRRDFMADISHELRTPLAVLRGELEAI-----QDGVRKF 273 Query: 135 VRET----EELLVRMDWLITSLLKLSRLDAGIVVFQSVQIDVNHLINAALRPFLIPMELH 190 ET + + + L+ L +LS D G + +Q +D+ L+ A F Sbjct: 274 TPETVASLQAEVGTLTKLVDDLHQLSMSDEGALAYQKAPVDLIPLLEVAGGAFRERFASR 333 Query: 191 DIDLQIDAPEGMIIQGDSGWLSEAIQNILKNCMESTGENGKIEIVCTDNPLFTEITIHDS 250 + LQ P+ + + GD L + N+L+N + T G ++I + +T DS Sbjct: 334 GLKLQFSLPDSITVFGDRDRLMQLFNNLLENSLRYTDSGGSLKISAEQHDKTVRLTFADS 393 Query: 251 GAGFEKEDLPSLFDRFYR---GTNPNATGYGIGLSLCKMIITRQGGTITAKNHPQGGAIF 307 G + L LF+RFYR N + G G+GL++C I+ G I A + P GG Sbjct: 394 APGVSDDQLQKLFERFYRTEGSRNRASGGSGLGLAICLNIVEAHNGRIIAAHSPFGGVSI 453 Query: 308 AIRFP 312 + P Sbjct: 454 TVELP 458 Score = 94.4 bits (233), Expect = 2e-19, Method: Compositional matrix adjust. Identities = 66/245 (26%), Positives = 111/245 (45%), Gaps = 12/245 (4%) Query: 75 EITKMTLRIRDQNNALKKEKEHLADSLADIAHQLRTPLTSVNLILSLLANNPDENERKAF 134 E+ K+ + L+K ++ D +ADI+H+LRTPL + L + ++ + F Sbjct: 219 ELGKLAQDFNQLASTLEKNQQMRRDFMADISHELRTPLAVLRGELEAI-----QDGVRKF 273 Query: 135 VRET----EELLVRMDWLITSLLKLSRLDAGIVVFQSVQIDVNHLINAALRPFLIPMELH 190 ET + + + L+ L +LS D G + +Q +D+ L+ A F Sbjct: 274 TPETVASLQAEVGTLTKLVDDLHQLSMSDEGALAYQKAPVDLIPLLEVAGGAFRERFASR 333 Query: 191 DIDLQIDAPEGMIIQGDSGWLSEAIQNILKNCMESTGENGKIEIVCTDNPLFTEITIHDS 250 + LQ P+ + + GD L + N+L+N + T G ++I + +T DS Sbjct: 334 GLKLQFSLPDSITVFGDRDRLMQLFNNLLENSLRYTDSGGSLKISAEQHDKTVRLTFADS 393 Query: 251 GAGFEKEDLPSLFDRFYR---GTNPNATGYGIGLSLCKMIITRQGGTITAKNHPQGGAIF 307 G + L LF+RFYR N + G G+GL++C I+ G I A + P GG Sbjct: 394 APGVSDDQLQKLFERFYRTEGSRNRASGGSGLGLAICLNIVEAHNGRIIAAHSPFGGVSI 453 Query: 308 AIRFP 312 + P Sbjct: 454 TVELP 458 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.320 0.137 0.392 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 21,009,698 Number of extensions: 826777 Number of successful extensions: 4521 Number of sequences better than 1.0e-05: 235 Number of HSP's gapped: 4199 Number of HSP's successfully gapped: 235 Length of query: 313 Length of database: 38,378,431 Length adjustment: 106 Effective length of query: 207 Effective length of database: 26,153,027 Effective search space: 5413676589 Effective search space used: 5413676589 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 116 (49.3 bits)