BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0538.0018.p (330 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value BH0305 [MG] COG0702 Predicted nucleoside-diphosphate-sugar epime... 129 8e-30 Cgl1338 [MG] COG0702 Predicted nucleoside-diphosphate-sugar epim... 108 1e-23 DR0011 [MG] COG0702 Predicted nucleoside-diphosphate-sugar epime... 100 3e-21 all2598 [MG] COG0702 Predicted nucleoside-diphosphate-sugar epim... 99 1e-20 XF0241 [MG] COG0702 Predicted nucleoside-diphosphate-sugar epime... 93 6e-19 >BH0305 [MG] COG0702 Predicted nucleoside-diphosphate-sugar epimerases Length = 284 Score = 129 bits (323), Expect = 8e-30, Method: Compositional matrix adjust. Identities = 91/301 (30%), Positives = 143/301 (47%), Gaps = 24/301 (7%) Query: 12 MRYIVTGVDGQLASRVAETVLAEVDGRNLTFTCMKKDRIPKDTVQRWENAGVTIFEINYD 71 M+ +VTG GQL S V E +L V N+ + R PK + + GV + + ++ Sbjct: 1 MKLLVTGATGQLGSLVVEALLKTVPAENVAVSV----RDPKKA-EHLKAQGVDVRQGDFT 55 Query: 72 DIPSMERAFKDGDRIYIVSGLEVGRRVQQHKNAIDTAIKAGISHITYSSFIGATDPNYAH 131 S+ AF D+I I+S G RV QHK AI A + + I Y+S A D + Sbjct: 56 QPESLVSAFAGVDKILIISSAP-GDRVAQHKAAIQAAKENNVRFIAYTSIANAQDNPF-- 112 Query: 132 VFVTPDHTATENYLKSTGVTYNAMRNNLYLENYLTMYTMLALMSNNKWLTTAGEGRATLV 191 F+ DH TE + +G+ Y+ +RNN YLEN + T+ A+ S WLT+AG G+ Sbjct: 113 -FIAEDHRETEKAIVESGIPYSFLRNNWYLENEVG--TIQAVASGAPWLTSAGSGKVGWA 169 Query: 192 HKDDCXXXXXXXLLGKGKDNEAYNIVGSESVSVRDLCNLIKEVSGRDLEYTPVNAEQYYE 251 + D L G+G ++ Y + G ++ +L ++ + GRD+E V+ Y + Sbjct: 170 PRRDYADAAAAVLTGEGHEHTTYELSG-HPLTQEELAQVVSDALGRDVEVQQVDDATYEQ 228 Query: 252 HLEKMHIPREITGDFSCSPVPFCGDDLVTTDASIKEGLLNVQSDAIEALTGQKPKTARDI 311 + IP E+ +PF +V I+EG LNV S E + G+ +D Sbjct: 229 AMSGAGIPEEV--------LPF----IVGIQQGIREGYLNVVSGDFEKVLGRPLTPLKDA 276 Query: 312 I 312 + Sbjct: 277 V 277 >Cgl1338 [MG] COG0702 Predicted nucleoside-diphosphate-sugar epimerases Length = 286 Score = 108 bits (270), Expect = 1e-23, Method: Compositional matrix adjust. Identities = 76/291 (26%), Positives = 136/291 (46%), Gaps = 11/291 (3%) Query: 12 MRYIVTGVDGQLASRVAETVLAEVDGRNLTFTCMKKDRIPKDTVQRWENAGVTIFEINYD 71 MR VTG G L V +++L + + ++ + D R GV FE Sbjct: 5 MRIAVTGATGSLGGHVVDSLLNKGVAASDIVAIVRNEEKAADLKARGIALGVATFE---- 60 Query: 72 DIPSMERAFKDGDRIYIVSGLEVGRRVQQHKNAIDTAIKAGISHITYSSFIGATDPNYAH 131 D ++ A + DR+ +SG EVG+RV QH N I+ A AG++ I Y+S + + + Sbjct: 61 DEAALTAALEGVDRLVFISGSEVGQRVAQHTNVINAAKAAGVTFIAYTSLL---NLGTSK 117 Query: 132 VFVTPDHTATENYLKSTGVTYNAMRNNLYLENYLTMYTMLALMSNNKWLTTAGEGRATLV 191 + + P+H ATE L +G+ + +RN Y ENY + ++ A + K A R + Sbjct: 118 LALAPEHIATEKLLAESGIDHALLRNGWYWENYES--SIGAAKATGKVFGAAEGARVSAA 175 Query: 192 HKDDCXXXXXXXLLGKGKDNEAYNIVGSESVSVRDLCNLIKEVSGRDLEYTPVNAEQYYE 251 + D + + + Y + G+ +++ ++ I EV G + EY ++ E+Y Sbjct: 176 ARKDYAEAAAVVITSDNQAGKVYELAGAPALTYPEIAAGIGEVIGSEAEYVNLSVEEYQN 235 Query: 252 HLEKMHIPREITGDFSCSPVPFCGDDLVTTDASIKEGLLNVQSDAI-EALT 301 LE+ +P E + P + + +D++ + L+ S +I EAL+ Sbjct: 236 ALEQAGVPAEFAALLAGMD-PIIAEGALYSDSTDLQDLIGRPSTSIVEALS 285 >DR0011 [MG] COG0702 Predicted nucleoside-diphosphate-sugar epimerases Length = 293 Score = 100 bits (250), Expect = 3e-21, Method: Compositional matrix adjust. Identities = 67/247 (27%), Positives = 113/247 (45%), Gaps = 20/247 (8%) Query: 62 GVTIFEINYDDIPSMERAFKDGDRIYIVSGLEVGRRVQQHKNAIDTAIKAGISHITYSSF 121 GV I + +Y+ +RA R+ ++S ++ R QH+ I+ A AG+ + Y+S Sbjct: 53 GVQIRQADYNSPEGWDRALAGVQRLLLISSSDLNDRADQHRTVIEAASAAGVELLAYTSL 112 Query: 122 IGATDPNYAHVFVTPDHTATENYLKSTGVTYNAMRNNLYLENYLTMYTMLALMSNNKWLT 181 + A + A + + DH ATE L +GV + +RN YLENY + + L Sbjct: 113 LKA---DTARMSLAADHQATEKLLTESGVPFVLLRNGWYLENY----DLAQALQTGSVLG 165 Query: 182 TAGEGRATLVHKDDCXXXXXXXLLGKGKDNEAYNIVGSESVSVRDLCNLIKEVSGRDLEY 241 AG GR + + D L G+ + Y + G E+ S+ +L + + SG+D++Y Sbjct: 166 AAGTGRISAASRKDLAEAAAAALTRDGQAGKVYELAGDEAFSLSELAAELSKQSGKDVQY 225 Query: 242 TPVNAEQYYEHLEKMHIPREITGDFSCSPVPFCGDDLVTTDASIKEGLLNVQSDAIEALT 301 E Y LE +P +PV LV++D + G L + + + L Sbjct: 226 RNFAPEDYQRTLEGFGLP---------APVAQM---LVSSDEGVARGELELPNSDLRELI 273 Query: 302 GQKPKTA 308 G +P T+ Sbjct: 274 G-RPSTS 279 >all2598 [MG] COG0702 Predicted nucleoside-diphosphate-sugar epimerases Length = 284 Score = 98.6 bits (244), Expect = 1e-20, Method: Compositional matrix adjust. Identities = 62/248 (25%), Positives = 119/248 (47%), Gaps = 10/248 (4%) Query: 15 IVTGVDGQLASRVAETVLAEVDGRNLTFTCMKKDRIPKDTVQRWENAGVTIFEINYDDIP 74 ++T GQL V + +L V L ++ V + + GV + +I+Y Sbjct: 3 VITAASGQLGRLVLQELLKSVPANKLVAAVRNPEK-----VSDFASLGVQVRQIDYTQPH 57 Query: 75 SMERAFKDGDRIYIVSGLEVGRRVQQHKNAIDTAIKAGISHITYSSFIGATDPNYAHVFV 134 +++ AF +++ ++S E+G RV QHKN I+ +AG+ + Y+S + A + + + + Sbjct: 58 TLDIAFAGAEKVLLISSSEIGSRVPQHKNVINACKQAGVKLLAYTSLLHA---DSSPLPL 114 Query: 135 TPDHTATENYLKSTGVTYNAMRNNLYLENYLTMYTMLALMSNNKWLTTAGEGRATLVHKD 194 +H TE LK +GV Y +RN+ Y ENY+T + + + AGEG+ + Sbjct: 115 AAEHQQTETVLKESGVPYVILRNSWYNENYMTGIPV--ALEYGAVMGCAGEGKIASAARA 172 Query: 195 DCXXXXXXXLLGKGKDNEAYNIVGSESVSVRDLCNLIKEVSGRDLEYTPVNAEQYYEHLE 254 D LL + + Y + G + ++ + I ++SG+ + Y ++ ++Y L+ Sbjct: 173 DYAAAAATVLLAHDQAGKVYELAGDVAYTLSEFATEISKLSGKQVIYQNLSEDEYIHVLK 232 Query: 255 KMHIPREI 262 +P I Sbjct: 233 NAGLPESI 240 >XF0241 [MG] COG0702 Predicted nucleoside-diphosphate-sugar epimerases Length = 293 Score = 93.2 bits (230), Expect = 6e-19, Method: Compositional matrix adjust. Identities = 75/303 (24%), Positives = 136/303 (44%), Gaps = 23/303 (7%) Query: 13 RYIVTGVDGQLASRVAETVLAEVDGRNLTFTCMKKDRIPKDTVQRWENAGVTIFEINYDD 72 R +VTG GQL + V E +L ++ +L + R PK V + GV ++Y D Sbjct: 7 RILVTGASGQLGALVIEELLKKIPASHL----IAAARDPKALVA-FSRCGVETRLLDYTD 61 Query: 73 IPSMERAFKDGDRIYIVSGLEVGRRVQQHKNAIDTAIKAGISHITYSSFIGATDPNYAHV 132 S++ A + +R+ +VS + +R+ QH+N I+ A +AG+ Y+S + A + + + Sbjct: 62 QTSIDAALQGVERLLLVSSNAIDQRLAQHRNVIEAAARAGVGLFAYTSLLHADNSS---L 118 Query: 133 FVTPDHTATENYLKSTGVTYNAMRNNLYLENYLTMYTMLALMSNNKWLTTAGEGRATLVH 192 + DH TE LK++ + Y +RN Y ENY ++ A + + L +AG GR Sbjct: 119 LLAKDHVQTEALLKASEIPYVLLRNGWYTENYTD--SIGAALVHGAVLGSAGTGRIAAAT 176 Query: 193 KDDCXXXXXXXLLGK-GKDNEAYNIVGSESVSVRDLCNLIKEVSGRDLEYTPVNAEQYYE 251 + D L+ + Y + G E+ ++ + I + SG+ + Y + +Y Sbjct: 177 RADYAAAAAAILVSDVDQAGRTYELAGDEAFTMPEYAAEITQQSGKPVIYRDLPEAEYAA 236 Query: 252 HLEKMHIPREITGDFSCSPVPFCGDDLVTTDASIKEGLLNVQSDAIEALTGQKPKTARDI 311 L ++ +P + S D +G L S + L G+ R++ Sbjct: 237 ILMQVGLPESFAAILAQS------------DIGASQGTLFDDSHQLSTLIGRPTTPLREV 284 Query: 312 IGK 314 + K Sbjct: 285 VAK 287 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.317 0.134 0.394 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 24,323,837 Number of extensions: 968479 Number of successful extensions: 7910 Number of sequences better than 1.0e-05: 18 Number of HSP's gapped: 7881 Number of HSP's successfully gapped: 18 Length of query: 330 Length of database: 38,378,431 Length adjustment: 107 Effective length of query: 223 Effective length of database: 26,037,693 Effective search space: 5806405539 Effective search space used: 5806405539 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.6 bits) S2: 116 (49.3 bits)