BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0538.0003.p (287 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value BS_yefB [L] COG1961 Site-specific recombinases, DNA invertase Pi... 126 5e-29 CAC1228 [L] COG1961 Site-specific recombinases, DNA invertase Pi... 62 1e-09 SMc02300 [L] COG1961 Site-specific recombinases, DNA invertase P... 58 2e-08 SMa0785 [L] COG1961 Site-specific recombinases, DNA invertase Pi... 58 2e-08 CAC2247 [L] COG1961 Site-specific recombinases, DNA invertase Pi... 54 2e-07 >BS_yefB [L] COG1961 Site-specific recombinases, DNA invertase Pin homologs Length = 346 Score = 126 bits (316), Expect = 5e-29, Method: Compositional matrix adjust. Identities = 12/216 (5%), Positives = 36/216 (16%), Gaps = 21/216 (9%) Query: 37 GGSTPSMVAGKKKQSIYWNGSSVQQILENPDYSGDMVKGRETTISVTNKARRERTEADFI 96 S+ G + + + +G R E + Sbjct: 5 RIPHSSLEVSTLGLGTMTFGEQNSEADAHAQLDYAVAQGINLIDVAEMYPVPPRPETQGL 64 Query: 97 VVKETHEAIISRDVFDTVQQLIESNRRRSPENPDVSSRPHQNVNLFTGVIFCEDCGRGLH 156 + + + + + R + + ++ LH Sbjct: 65 TETYVGNWLAKHGSREKLIIASKVSGPS---------RNNDKGIRPDQALDRKNIREALH 115 Query: 157 YQRNCKGYICGRSHKHGNKACKKHRVREKALS----RYLEDVITKSDYDDYVVNRDAELV 212 ++ + + S ++ D Sbjct: 116 DSLKRLQTDYLDLYQVHWPQRPTNCFGKLGYSWTDSAPAVSLLDTLDALAEY----QRAG 171 Query: 213 -KLLQDKGQIEA---SMSAALDSRKLDEVKAVVTSA 244 A L + + + Sbjct: 172 KIRYIGVSNETAFGVMRYLHLADKHDLPRIVTIQNP 207 >CAC1228 [L] COG1961 Site-specific recombinases, DNA invertase Pin homologs Length = 346 Score = 61.6 bits (148), Expect = 1e-09, Method: Compositional matrix adjust. Identities = 0/155 (0%), Positives = 0/155 (0%), Gaps = 15/155 (9%) Query: 45 AGKK--KQSIYWNGSSVQQILENPDYSGDMVKGRETTISVTNKARRERTEADFIVVKETH 102 + P + + T + ++ I + Sbjct: 229 ELLAYSCLGF-GTLTGKYLNGAKPAGARNT-LFSRFTRYSGEQTQKAVAAYVDIARRHGL 286 Query: 103 EAIISRDVFDTVQQLIESNRRRSPENPDVSSRPHQNVNLFTGVIFCEDCGRGL-HYQRNC 161 + F Q ++ D + + ED + + Sbjct: 287 DPAQMALAFVRRQP-FVASTLLGATTMDQLKTNIE----SLHLELSEDVLAEIEAVHQVY 341 Query: 162 KG-----YICGRSHKHGNKACKKHRVREKALSRYL 191 Sbjct: 342 TY 376 >SMc02300 [L] COG1961 Site-specific recombinases, DNA invertase Pin homologs Length = 346 Score = 57.8 bits (138), Expect = 2e-08, Method: Compositional matrix adjust. Identities = 0/153 (0%), Positives = 0/153 (0%), Gaps = 22/153 (14%) Query: 46 GKKKQSIYW---NGSSVQQILENPDYSGDMVKGRETTI------SVTNKARRERTEADFI 96 + + + + + ARR + Sbjct: 232 AYSCLGFGTLTGKYLNGAKPAGARNTLFSRFTRYSGEQTQKAVAAYVDIARRHGLD---P 288 Query: 97 VVKETHEAIISRDVFDTVQQLIESNRRRSPENPDVSSR-PHQNVNLFTGVIFCEDCGRGL 155 V T+ + + N + ++V + Sbjct: 289 AQMALAFVRRQPFVASTLLGATTMD--QLKTNIESLHLELSEDVLAEIEAVHQVYTYPAP 346 Query: 156 --HYQR---NCKG-YICGRS-HKHGNKACKKHR 181 Sbjct: 347 379 >SMa0785 [L] COG1961 Site-specific recombinases, DNA invertase Pin homologs Length = 346 Score = 57.8 bits (138), Expect = 2e-08, Method: Compositional matrix adjust. Identities = 0/153 (0%), Positives = 0/153 (0%), Gaps = 22/153 (14%) Query: 46 GKKKQSIYW---NGSSVQQILENPDYSGDMVKGRETTI------SVTNKARRERTEADFI 96 + + + + + ARR + Sbjct: 232 AYSCLGFGTLTGKYLNGAKPAGARNTLFSRFTRYSGEQTQKAVAAYVDIARRHGLD---P 288 Query: 97 VVKETHEAIISRDVFDTVQQLIESNRRRSPENPDVSSR-PHQNVNLFTGVIFCEDCGRGL 155 V T+ + + N + ++V + Sbjct: 289 AQMALAFVRRQPFVASTLLGATTMD--QLKTNIESLHLELSEDVLAEIEAVHQVYTYPAP 346 Query: 156 --HYQR---NCKG-YICGRS-HKHGNKACKKHR 181 Sbjct: 347 379 >CAC2247 [L] COG1961 Site-specific recombinases, DNA invertase Pin homologs Length = 346 Score = 54.3 bits (129), Expect = 2e-07, Method: Compositional matrix adjust. Identities = 0/186 (0%), Positives = 0/186 (0%), Gaps = 16/186 (8%) Query: 28 PSPASCLKRGGSTPSMVAGKKKQSIYWNGSSVQQILENPDYSGDMVKGRETTISVTNKAR 87 S + G + + + ++ + R T S + Sbjct: 208 YSLLNRSFEVGLAEVSQY-EGVELLAYSCLGFGTLTGKYLNGAKPAGARNTLFSRFTRYS 266 Query: 88 RERTEADFIVVKETHEAIISRDVFDTVQQLIESNRRRSPENPDVSSRPHQNVNLFTGVIF 147 E+T+ D RR+ + + Sbjct: 267 GEQTQKAV-AAYVDIARRHGLDPAQMALAF---VRRQPF--VASTLLGATTM-DQLKTNI 319 Query: 148 CEDCGRGL------HYQRNCKGYICGRSHKHGNKACKKHRVREKALSRYLEDVI--TKSD 199 Sbjct: 320 ESLHLELSEDVLAE 379 Query: 200 YDDYVV 205 Sbjct: 380 385 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.317 0.132 0.374 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 19,561,117 Number of extensions: 749562 Number of successful extensions: 1872 Number of sequences better than 1.0e-05: 7 Number of HSP's gapped: 1870 Number of HSP's successfully gapped: 7 Length of query: 287 Length of database: 38,378,431 Length adjustment: 105 Effective length of query: 182 Effective length of database: 26,268,361 Effective search space: 4780841702 Effective search space used: 4780841702 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 115 (48.9 bits)