BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0535.0016.p (238 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value Cgl0399 [TK] COG0745 Response regulators consisting of a CheY-li... 155 5e-38 CC1293 [TK] COG0745 Response regulators consisting of a CheY-lik... 153 2e-37 Rv0981 [TK] COG0745 Response regulators consisting of a CheY-lik... 149 3e-36 MT1009 [TK] COG0745 Response regulators consisting of a CheY-lik... 149 3e-36 MT0510 [TK] COG0745 Response regulators consisting of a CheY-lik... 146 2e-35 >Cgl0399 [TK] COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Length = 232 Score = 155 bits (392), Expect = 5e-38, Method: Compositional matrix adjust. Identities = 94/230 (40%), Positives = 129/230 (56%), Gaps = 12/230 (5%) Query: 12 MIHILVVEDDRHARRLLEAVLKREGYLVSTAEDGARAMDVLDQQHIDLIVLDIMMPNMDG 71 M IL+VED+ L +L++EG+ A DG A+ + ID+++LD+M+P M G Sbjct: 1 MTRILIVEDEESLADPLAFLLRKEGFDTIIAGDGPTALVEFSRNEIDIVLLDLMLPGMSG 60 Query: 72 YEFAKELRDAGSLIPVLMATAKHLPEDKKKGFRLGIDDYMTKPVDTEEMLLRIGALLRRS 131 + KELR S +PV+M TA+ DK G LG DDY+TKP + E++ RI A+LRR Sbjct: 61 TDVCKELRSV-STVPVIMVTARDSEIDKVVGLELGADDYVTKPYSSRELIARIRAVLRRR 119 Query: 132 QIASARK---------LVVGNVVLDYDALTVTRGEEKQTLPQKEFYLLYKLLSYPDRIFT 182 + L G V +D D+ TVT G E ++P KEF LL LL R+ T Sbjct: 120 GVTETEAEELPLDDQILEGGRVRMDVDSHTVTVGGEPVSMPLKEFDLLEYLLRNAGRVLT 179 Query: 183 RIQLMDEIWGMESESSDTTVNVHINRLRKRFEGYPEFE--LVSVRGLGYK 230 R QL+D IWG + T++VH+ RLR + E P LV+VRGLGYK Sbjct: 180 RGQLIDRIWGADYVGDTKTLDVHVKRLRSKIEEEPSRPRYLVTVRGLGYK 229 >CC1293 [TK] COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Length = 242 Score = 153 bits (387), Expect = 2e-37, Method: Compositional matrix adjust. Identities = 99/234 (42%), Positives = 133/234 (56%), Gaps = 20/234 (8%) Query: 13 IHILVVEDDRHARRLLEAVLKREGYLVSTAEDG------ARAMDV----LDQQHIDLIVL 62 +HILVVEDD LE LK EGY V A DG AR +D LDQ+ + I+L Sbjct: 1 MHILVVEDDTRVADFLERGLKAEGYKVRVARDGVSGLEAARDLDAMLRELDQRGV--ILL 58 Query: 63 DIMMPNMDGYEFAKELRDAGSLIPVLMATAKHLPEDKKKGFRLGIDDYMTKPVDTEEMLL 122 D+M+P M G E + LR +G L PVLM TA +D+ G R G DDY+ KP EE+L Sbjct: 59 DLMLPKMTGMEVCQTLRASGVLTPVLMLTALGAVDDRVTGLRTGADDYLVKPFSFEELLA 118 Query: 123 RIGALLRRS--QIASA-RKLVVGNVVLDYDALTVTRGEEKQTLPQKEFYLLYKLLSYPDR 179 RI ALLRRS Q A A R L GNV LD + V+R E+ L +E LL LS P R Sbjct: 119 RIEALLRRSRDQRAPANRTLKAGNVELDRTTMRVSRDGEEVVLTARELALLELFLSSPGR 178 Query: 180 IFTRIQLMDEIWGMESESSDTTVNVHINRLRKRFEGYPEFE---LVSVRGLGYK 230 + +R +++ +WG++ + V+V++ RLR + + P + +VRGLGY+ Sbjct: 179 VLSRERILSNVWGVDEDPLTNVVDVYVRRLRAKID--PPLASSFITTVRGLGYR 230 >Rv0981 [TK] COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Length = 230 Score = 149 bits (377), Expect = 3e-36, Method: Compositional matrix adjust. Identities = 82/221 (37%), Positives = 129/221 (58%), Gaps = 4/221 (1%) Query: 13 IHILVVEDDRHARRLLEAVLKREGYLVSTAEDGARAMDVLDQQHIDLIVLDIMMPNMDGY 72 + ILVV+DDR R L L GY V A DG A+D++ D +VLD+MMP +DG Sbjct: 3 VRILVVDDDRAVRESLRRSLSFNGYSVELAHDGVEALDMIASDRPDALVLDVMMPRLDGL 62 Query: 73 EFAKELRDAGSLIPVLMATAKHLPEDKKKGFRLGIDDYMTKPVDTEEMLLRIGALLRRSQ 132 E ++LR G +P+L+ TA+ ++ G G DDY+ KP EE+L R+ ALLRR++ Sbjct: 63 EVCRQLRGTGDDLPILVLTARDSVSERVAGLDAGADDYLPKPFALEELLARMRALLRRTK 122 Query: 133 ---IASARKLVVGNVVLDYDALTVTRGEEKQTLPQKEFYLLYKLLSYPDRIFTRIQLMDE 189 A + + ++ LD V RG+ + +L + EF LL L++ P R+ TR ++++E Sbjct: 123 PEDAAESMAMRFSDLTLDPVTREVNRGQRRISLTRTEFALLEMLIANPRRVLTRSRILEE 182 Query: 190 IWGMESESSDTTVNVHINRLRKRFEGYPEFELV-SVRGLGY 229 +WG + +S + V++ LR++ E E L+ +VRG+GY Sbjct: 183 VWGFDFPTSGNALEVYVGYLRRKTEADGEPRLIHTVRGVGY 223 >MT1009 [TK] COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Length = 230 Score = 149 bits (377), Expect = 3e-36, Method: Compositional matrix adjust. Identities = 82/221 (37%), Positives = 129/221 (58%), Gaps = 4/221 (1%) Query: 13 IHILVVEDDRHARRLLEAVLKREGYLVSTAEDGARAMDVLDQQHIDLIVLDIMMPNMDGY 72 + ILVV+DDR R L L GY V A DG A+D++ D +VLD+MMP +DG Sbjct: 3 VRILVVDDDRAVRESLRRSLSFNGYSVELAHDGVEALDMIASDRPDALVLDVMMPRLDGL 62 Query: 73 EFAKELRDAGSLIPVLMATAKHLPEDKKKGFRLGIDDYMTKPVDTEEMLLRIGALLRRSQ 132 E ++LR G +P+L+ TA+ ++ G G DDY+ KP EE+L R+ ALLRR++ Sbjct: 63 EVCRQLRGTGDDLPILVLTARDSVSERVAGLDAGADDYLPKPFALEELLARMRALLRRTK 122 Query: 133 ---IASARKLVVGNVVLDYDALTVTRGEEKQTLPQKEFYLLYKLLSYPDRIFTRIQLMDE 189 A + + ++ LD V RG+ + +L + EF LL L++ P R+ TR ++++E Sbjct: 123 PEDAAESMAMRFSDLTLDPVTREVNRGQRRISLTRTEFALLEMLIANPRRVLTRSRILEE 182 Query: 190 IWGMESESSDTTVNVHINRLRKRFEGYPEFELV-SVRGLGY 229 +WG + +S + V++ LR++ E E L+ +VRG+GY Sbjct: 183 VWGFDFPTSGNALEVYVGYLRRKTEADGEPRLIHTVRGVGY 223 >MT0510 [TK] COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Length = 230 Score = 146 bits (369), Expect = 2e-35, Method: Compositional matrix adjust. Identities = 88/226 (38%), Positives = 129/226 (57%), Gaps = 9/226 (3%) Query: 12 MIHILVVEDDRHARRLLEAVLKREGYLVSTAEDGARAMDVLDQQHIDLIVLDIMMPNMDG 71 M +L+VED+ L +L++EG+ + DG A+ D+ D+++LD+M+P M G Sbjct: 4 MTSVLIVEDEESLADPLAFLLRKEGFEATVVTDGPAALAEFDRAGADIVLLDLMLPGMSG 63 Query: 72 YEFAKELRDAGSLIPVLMATAKHLPEDKKKGFRLGIDDYMTKPVDTEEMLLRIGALLRR- 130 + K+LR A S +PV+M TA+ DK G LG DDY+TKP E++ RI A+LRR Sbjct: 64 TDVCKQLR-ARSSVPVIMVTARDSEIDKVVGLELGADDYVTKPYSARELIARIRAVLRRG 122 Query: 131 ----SQIASARKLVVGNVVLDYDALTVTRGEEKQTLPQKEFYLLYKLLSYPDRIFTRIQL 186 S+++ L G V +D + V+ + TLP KEF LL L+ R+ TR QL Sbjct: 123 GDDDSEMSDG-VLESGPVRMDVERHVVSVNGDTITLPLKEFDLLEYLMRNSGRVLTRGQL 181 Query: 187 MDEIWGMESESSDTTVNVHINRLRKRFEGYPE--FELVSVRGLGYK 230 +D +WG + T++VH+ RLR + E P LV+VRGLGYK Sbjct: 182 IDRVWGADYVGDTKTLDVHVKRLRSKIEADPANPVHLVTVRGLGYK 227 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.321 0.138 0.390 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 17,235,459 Number of extensions: 704244 Number of successful extensions: 2469 Number of sequences better than 1.0e-05: 514 Number of HSP's gapped: 2036 Number of HSP's successfully gapped: 514 Length of query: 238 Length of database: 38,378,431 Length adjustment: 103 Effective length of query: 135 Effective length of database: 26,499,029 Effective search space: 3577368915 Effective search space used: 3577368915 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 114 (48.5 bits)