BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0535.0007.p (438 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value BH1154_2 [T] COG0642 Signal transduction histidine kinase 99 2e-20 lin2515 [T] COG0642 Signal transduction histidine kinase 84 5e-16 CAC0317 [T] COG0642 Signal transduction histidine kinase 74 3e-13 BH0819 [T] COG0642 Signal transduction histidine kinase 68 3e-11 AGc1799_2 [T] COG0642 Signal transduction histidine kinase 58 4e-08 >BH1154_2 [T] COG0642 Signal transduction histidine kinase Length = 274 Score = 98.6 bits (244), Expect = 2e-20, Method: Compositional matrix adjust. Identities = 72/266 (27%), Positives = 126/266 (47%), Gaps = 21/266 (7%) Query: 188 LEGGYLDYPITVSGDDELSSLAQSINEMRKSFMERLNSEERARLANSELVTAMSHDLRTP 247 ++ G+ + V G L+ LAQ+IN M+K + + ++ +EL+T +SHDLRTP Sbjct: 11 IKSGHTPQDLPVRGRSALALLAQNINTMKKGMKQSEREQAKSERLKTELITNVSHDLRTP 70 Query: 248 LTALVGYLDIIAYQKYGTEDNLNKYIHNSREKAYQIKTLSDQLFEYFTVFNTDEGDLALD 307 LT+++ Y +++ K E YI KA ++K L D LFE + ++ +L L+ Sbjct: 71 LTSIITYTELL---KDADEQERADYIEIIDRKARRLKILIDDLFEA-SKMSSGNIELTLE 126 Query: 308 TFDGMPLIDQLIDEQLLGLQNHRIQFEYLPCGTPFQIDINLTAMRRVFDNLFSNITKYAG 367 T D + L+ Q + E L+ +Q P I + + RVFDNL NI KY+ Sbjct: 127 TVDVLQLLQQALAEYGEALEQSSLQLRISVPEEPLYIKADGQKIWRVFDNLIQNILKYSL 186 Query: 368 TSKPVIIKCCIANQKLRLDIQN----HIGPNPETI-------------DSTGIGMKTCEK 410 V + + + + I+N +G N + + + +G+G+ + Sbjct: 187 EHTRVYLSVKEKKETVEIIIKNVAKYELGDNVDELLERFKRGDQSRNTEGSGLGLAIAKS 246 Query: 411 IIRQHKGSLAVTRTEDIYSACIHLPV 436 I+ H+G L + D++ I LP+ Sbjct: 247 IVDLHEGYLDIDVDGDLFKVIIQLPM 272 >lin2515 [T] COG0642 Signal transduction histidine kinase Length = 182 Score = 83.6 bits (205), Expect = 5e-16, Method: Compositional matrix adjust. Identities = 0/251 (0%), Positives = 0/251 (0%), Gaps = 20/251 (7%) Query: 204 ELSSLAQSINEMRKSFMERLNSEERARLANSELVTAMSHDLRTPLTALVGYLDIIAYQKY 263 Sbjct: 131 190 Query: 264 GTEDNLNKYIHNSREKAYQIKTLSDQLFEYFTVFNTDEGDLALDTFDGMPLIDQLIDEQL 323 Sbjct: 191 - 249 Query: 324 LGLQNHRIQFEYLPCGTPFQIDINLTAMRRVFDNLFSNITKYAGTSKPVIIKCCIANQKL 383 Sbjct: 250 309 Query: 384 RLDIQNHIGPNPETID------------------STGIGMKTCEKIIRQHKGSLAVTRTE 425 Sbjct: 310 - 368 Query: 426 DIYSACIHLPV 436 Sbjct: 369 379 >CAC0317 [T] COG0642 Signal transduction histidine kinase Length = 498 Score = 74.3 bits (181), Expect = 3e-13, Method: Compositional matrix adjust. Identities = 60/262 (22%), Positives = 122/262 (46%), Gaps = 26/262 (9%) Query: 183 NEIKI----LEGGYLDYPITVSGDDELSSLAQSINEMRKSFMERLNSEERARLANSELVT 238 N++KI ++ G LD+ + DE+ L + + MRK E + + + EL++ Sbjct: 215 NQLKIGTEKIKHGNLDFKVRAESSDEIGELCDAFDSMRKKLKESVELQAQYENNRKELIS 274 Query: 239 AMSHDLRTPLTALVGYLDIIAYQKYGTEDNLNKYIHNSREKAYQIKTLSDQLFEYFTVFN 298 +SHDL+TP+T++ GY++ I T + + KY++ K + L ++L Y + + Sbjct: 275 NISHDLKTPITSIKGYIEGIRDGVADTPEKMEKYVNTIYNKTQSMNYLIEELLTY-SKLD 333 Query: 299 TDEGDLALDTFDGMPLIDQLIDEQLLGLQNHRIQFEY-LPCGTPFQIDINLTAMRRVFDN 357 + D + ++ L++E ++ + ++F Y + I++ + RV N Sbjct: 334 LKKLPFYFIDMDFVSYMNDLMEEFKFDVEKNNMEFSYDNHIKGKANVRIDVQNINRVISN 393 Query: 358 LFSNITKYAGTSKPVI-IKCCIANQKLRLDIQ-NHIGPNPETI----------------- 398 + SN KY I ++ N+++ + I+ N +G + E + Sbjct: 394 IISNSIKYMDKEHGKISVEVDSNNEEVLVGIKDNGMGISEEALPYVFDRFYREDFSRNTS 453 Query: 399 -DSTGIGMKTCEKIIRQHKGSL 419 +G+G+ C+KII +H GS+ Sbjct: 454 KGGSGLGLAICKKIIEEHGGSI 475 >BH0819 [T] COG0642 Signal transduction histidine kinase Length = 309 Score = 68.2 bits (165), Expect = 3e-11, Method: Compositional matrix adjust. Identities = 52/209 (24%), Positives = 105/209 (50%), Gaps = 21/209 (10%) Query: 172 NRKTSYIGVLENEIKILEGGYLDYPITVSGDDELSSLAQSINEMRKSFMERLNSEERARL 231 N++ +Y+ +EI+ + + + +GD++L L ++IN++ + + + +R L Sbjct: 27 NKQLAYVTHKLDEIRTSQSA--ETVMVFTGDEQLRELLRAINDLIEEHNQVTATYQRTEL 84 Query: 232 ANSELVTAMSHDLRTPLTALVGYLDIIAYQKYGTEDNLNKYIHNSREKAYQIKTLSDQLF 291 + +++ +SHDL+TPLT + GY++ I K N RE+ +++T + ++ Sbjct: 85 SMRKMLANISHDLKTPLTVIHGYVETILAGKGSA---------NDRERLEKVQTKTIEII 135 Query: 292 E----YFTVFNTDEGDLALDTFDGMPLIDQLIDEQLLG----LQNHRIQFEYLPCGTPFQ 343 E +F + + GD L T + +++L ++L +QN ++Q E PF Sbjct: 136 ELINKFFDLAKLEAGDQNL-TLKKVA-VNELCKNRILSYFDLIQNEKLQVEIEIPSQPFY 193 Query: 344 IDINLTAMRRVFDNLFSNITKYAGTSKPV 372 + + A+ R+ DNL SN +Y K V Sbjct: 194 VLADEKALDRILDNLISNAIRYGKDGKMV 222 >AGc1799_2 [T] COG0642 Signal transduction histidine kinase Length = 323 Score = 57.8 bits (138), Expect = 4e-08, Method: Compositional matrix adjust. Identities = 54/228 (23%), Positives = 103/228 (45%), Gaps = 28/228 (12%) Query: 223 LNSEERARLAN---SELVTAMSHDLRTPLTALVGYLDIIAYQKYGTEDNLNKYIHNSREK 279 L +ERA+ AN SE + MSH+LRTPL A++G+ +I+ + +G + KY +R+ Sbjct: 78 LAEKERAQAANRAKSEFLANMSHELRTPLNAILGFSEILQNEMFGPVGS-PKYSEYARDI 136 Query: 280 AYQIKTLSDQLFEYFTVFNTDEGDLAL--DTFDGMPLIDQLIDEQLLGLQNHRIQFEYLP 337 K L + + + + + G + + +T D PLI++ + + + I + Sbjct: 137 HDSGKHLLNVINDILDMSKIEAGHMRINRETIDLAPLIEETLRLTAIQAEQKNITVQQKV 196 Query: 338 C-GTPFQIDINLTAMRRVFDNLFSNITKYAGTSKPVIIKCCIANQKLRLDIQN------- 389 C G Q D AM+++ N+ SN K+ G + ++ + + L I + Sbjct: 197 CAGLTMQGD--RRAMKQIMLNILSNAVKFTGDGGRIALRTHVHEAAMILTIADTGIGIPA 254 Query: 390 ----HIGPNPETIDS--------TGIGMKTCEKIIRQHKGSLAVTRTE 425 IG E + S +G+G+ +++ H G++ + E Sbjct: 255 QALQKIGQPFEQVQSQYAKSQGGSGLGLAISRSLVKLHGGTMKIRSCE 302 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.321 0.138 0.393 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 30,495,160 Number of extensions: 1278645 Number of successful extensions: 7689 Number of sequences better than 1.0e-05: 17 Number of HSP's gapped: 7718 Number of HSP's successfully gapped: 17 Length of query: 438 Length of database: 38,378,431 Length adjustment: 109 Effective length of query: 329 Effective length of database: 25,807,025 Effective search space: 8490511225 Effective search space used: 8490511225 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 117 (49.7 bits)