BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0534.0012.p (914 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value PA3921 [K] COG2909 ATP-dependent transcriptional regulator 236 2e-61 PA1760 [K] COG2909 ATP-dependent transcriptional regulator 199 2e-50 PA1759 [K] COG2909 ATP-dependent transcriptional regulator 140 7e-33 PA3420 [K] COG2909 ATP-dependent transcriptional regulator 72 4e-12 Cgl1963 [TK] COG2197 Response regulator containing a CheY-like r... 70 1e-11 >PA3921 [K] COG2909 ATP-dependent transcriptional regulator Length = 906 Score = 236 bits (601), Expect = 2e-61, Method: Compositional matrix adjust. Identities = 176/593 (29%), Positives = 272/593 (45%), Gaps = 31/593 (5%) Query: 13 SYYNLAMTITIVSAKLFIPPARSKSVVRPRLLERLNGSLQGKLTVLSAAAGYGKTTLASE 72 ++ + + + F PP S V RPRL RL L G+L +++A AG+GK++LA E Sbjct: 7 TFSGTPSAVLPTANRFFRPPLPSAHVARPRLCRRLRDGLDGRLLLIAAPAGFGKSSLAIE 66 Query: 73 WLAVCGRR--ATWLSLDAGDNDPARFLTYLFAACRSIGVNIGE---GVFAVLQSPQPPPA 127 + R + WL L + ++DP RFL L R +GE G+ + Q QP Sbjct: 67 FCESLDPRWQSLWLGLSSRESDPGRFLERLLDGLRQYHPTLGEEALGLLKMRQRHQPFAF 126 Query: 128 ESLLTALLNEISSDSEPS---ILVLDDYHVITAEPVNQAVAFLLEHLPPQMHLVIATRED 184 E+ L LL+E++ +P +LVLDDYH+ +++ + FLL HLP + L++ +R+ Sbjct: 127 ETWLDDLLDELAPCLDPQRPLLLVLDDYHLAQGAVLDRCLQFLLNHLPEGLVLLVTSRQR 186 Query: 185 XXXXXXXXXXXHQLTELRAADLRFNAAEAAEFLGGVMGLTLSAKDVMLLESRTEGWIAGL 244 QL EL DLR A E+ + GL L + L R+EGW+AGL Sbjct: 187 PDWHLARLRLSRQLLELSEQDLRLTAEESGALMAAS-GLELDEDALDALLERSEGWVAGL 245 Query: 245 QLAALSMQGRNDTTGFIQ-SFTGSHKFVLDYLIEEVLQQQPASIQAFLQFTSVLDKMCGP 303 +L L+ R D + G+ + + DYL+EEV+++QP +QAFL T+ ++ C Sbjct: 246 RLWLLA---RGDPEEQVSPGVHGADELIRDYLLEEVIERQPPEVQAFLAQTARFERFCAE 302 Query: 304 LCDAVLGKDSEGASRSTGQRTLEYLEHANLFLIPLDNERRWYRYHHLFADLLRERLNQGF 363 LCD V A L++L+ +FL+PLD +W+RYHHLF+DLL R F Sbjct: 303 LCDTVREAGDSAA-------ILDHLQQHQVFLVPLDENGQWFRYHHLFSDLLLARPLPDF 355 Query: 364 FPSEGGKEKTVSELHLRASQWYEDNXXXXXXXXXXXXXXXXXXXXXLTEG-EGMPLLFRG 422 PS G LHLRA W+ + L + LL Sbjct: 356 GPSAGS-------LHLRACGWFSRHGLLDQAVEQALRAGQPDVAASLVQNLSEEQLLAEQ 408 Query: 423 AVTPVLNWLQSLPEEELDAIPSLRVMYASALLMTGRLSSVEQKLQAAEQALHGAVLDEKT 482 + +L W LP+ L + P L ++Y AL + +L + E+ A + A DE Sbjct: 409 NIATLLRWKMDLPDSLLASTPRLILLYGWALALACQLDAAEEL--AGQLARFLPAPDESA 466 Query: 483 -RDLIGHIASIRAMLAVSKHQADPIAAESRRALEYLHPDNLAVRAAAAWTLGYAYQLQGE 541 RDL+ ++ ++A + D A R AL+ L + R TL +G+ Sbjct: 467 QRDLLAQWQALSGVIARGRGDIDKAEAHCREALQDLAGERYGTRLQCLSTLSNLAVTRGD 526 Query: 542 QGLAGAAYNEALSVSKRIGHVMISIMATLGRGNIQEAENRLPAAAGSYLQVLE 594 A +AL ++R G+ + + R + +A + A Q LE Sbjct: 527 FWQARNYNRDALEFAQRYGNPLFEALVHYDRARVLQARGEVARAEEEVRQGLE 579 Score = 78.2 bits (191), Expect = 6e-14, Method: Compositional matrix adjust. Identities = 39/63 (61%), Positives = 52/63 (82%) Query: 852 EKLSRRELEILQLIAQGLSNREIGDRMFLALSTVKGYNRNIFDKLQVSRRTEAIARARML 911 E LS REL +L+LIAQGLSN+EI +R+F++L TVK + R+I DKL V RRT+A+ARA+ + Sbjct: 843 EVLSGRELAVLELIAQGLSNQEISERLFISLHTVKSHARHINDKLGVERRTQAVARAKHM 902 Query: 912 GLL 914 GLL Sbjct: 903 GLL 905 >PA1760 [K] COG2909 ATP-dependent transcriptional regulator Length = 907 Score = 199 bits (505), Expect = 2e-50, Method: Compositional matrix adjust. Identities = 170/592 (28%), Positives = 266/592 (44%), Gaps = 39/592 (6%) Query: 18 AMTITIVSAKLFIPPARSKSVVRPR--LLERLNGSLQGKLTVLSAAAGYGKTTLASEW-- 73 A TI ++ KLF PP + PR L++RL + + VLSA AG+GK+T+ + Sbjct: 9 ASTIPLLQTKLF-PPGAGGLPLLPRQALIDRLYEARGRRAMVLSAPAGFGKSTILCQLRL 67 Query: 74 -LAVCGRRATWLSLDAGDNDPARFLTYLFAACRSIGVNIGEGVFAVLQSPQPPPAESLLT 132 L G WLS D D++P R + YL A+ + + G +L + P E +L Sbjct: 68 RLLEQGAAVAWLSCDETDSEPQRLIQYLLASIQRVVPAFGGNTANLLGTDVAVPLEGILD 127 Query: 133 ALLNEISSDSEPSILVLDDYHVITAEPVNQAVAFLLEHLPPQMHLVIATREDXXXXXXXX 192 A L ++ P L LDD+H I + V +L+E+LP + +V +TR Sbjct: 128 AFLADLRRLEGPLYLFLDDFHRIRHAALPHGVRYLIENLPDHVRVVASTRFRPRFLVDEP 187 Query: 193 XXXHQLTELRAADLRFNAAEAAEFLGGVMGLTLSAKDVMLLESRTEGWIAGLQLAALSMQ 252 L A DLR + E+ FL + GL L +++ LL RTEGWI L LAAL++ Sbjct: 188 TLKPWTFCLSAEDLRLSREESDAFLLDLKGLELGERELKLLFKRTEGWITALHLAALALS 247 Query: 253 GRNDTTGFIQSFTGSHKFVLDYLIEEVLQQQPASIQAFLQFTSVLDKMCGPLCDAVLGKD 312 D GF+ +G+ + + DYL E+VL PA +Q FL TSVLD+ LC+A+ G Sbjct: 248 RNTDREGFLLGLSGTERNIADYLAEDVLASLPADLQLFLDQTSVLDEFNAELCNALTG-- 305 Query: 313 SEGASRSTGQRTLEYLEHANLFLIPLDNERRWYRYHHLFADLLRERLNQGFFPSEGGKEK 372 R G L L++ LF+I LD++R W+RYHHLFA+ L+ RL++ P+ Sbjct: 306 -----RRDGLDMLMRLQNEQLFVIALDDQREWFRYHHLFAEFLQGRLSRHADPT------ 354 Query: 373 TVSELHLRASQWYEDNXXXXXXXXXXXXXXXXXXXXXLTEGEGMPLLFRGAVTPVLNWLQ 432 LH A++W E L E +G L+ V +L L Sbjct: 355 --PLLHA-AARWCEGRDLADRAIKYALRARDYLFAAELLERQGARLIAGNRVYGILGMLN 411 Query: 433 SLPEEELDAIPSLRVMYASALLMTGRLSSVEQKLQAAEQAL---HGAVLDEKTRDLIGHI 489 +P E + P ++ YA L R + E ++ L G V+ +L+ Sbjct: 412 GIPAEVIREHPVFQIFYAWQLAFEQRFAEAEALIEEVSHRLLQGRGKVMHFGLGELLAAA 471 Query: 490 ASIRAMLAVSKHQADPIAAESRRALEYLHPDNLAVRAAAAWTLGYAYQLQGE----QGLA 545 ++A++ + + + + +R L + + RA+ A+ L G+ G Sbjct: 472 QVLKALVLLYQDKLEACLKVARHWLSMVPSNQPVFRASLLCVQASAHALLGDYAEAAGAI 531 Query: 546 GAAYNEALSVSKRIGHVMISIMATL----------GRGNIQEAENRLPAAAG 587 G+A + V+ S++ +L GR + A NR+ G Sbjct: 532 GSAREDLKVADSEYLQVVTSLIESLICKESGDLERGRAIAESARNRVEQVFG 583 Score = 57.4 bits (137), Expect = 1e-07, Method: Compositional matrix adjust. Identities = 29/63 (46%), Positives = 44/63 (69%) Query: 852 EKLSRRELEILQLIAQGLSNREIGDRMFLALSTVKGYNRNIFDKLQVSRRTEAIARARML 911 + +S RE EIL+L+A GLSNR+I + L+ +T+K + N+F KL V RT+A+ + + L Sbjct: 842 QDVSHREREILRLVAAGLSNRDIAQAVHLSEATIKWHLHNLFAKLGVKSRTQAVLKGKSL 901 Query: 912 GLL 914 GLL Sbjct: 902 GLL 904 >PA1759 [K] COG2909 ATP-dependent transcriptional regulator Length = 901 Score = 140 bits (354), Expect = 7e-33, Method: Compositional matrix adjust. Identities = 120/428 (28%), Positives = 196/428 (45%), Gaps = 21/428 (4%) Query: 22 TIVSAKLFIPPARSKSVVRPRLLERLNGSLQGKLTVLSAAAGYGKTT----LASEWLAVC 77 ++ +++ P ++ +RP + L+ + ++ + SA AG+GKT LA E V Sbjct: 11 SLSRSRIVPPQVPAEYSLRPAIRNLLDRNPHSRVLMFSAPAGFGKTCALAALARE-RTVA 69 Query: 78 GRRATWLSLDAGDNDPARFLTYLFAACRSIGVNIGEGVFAVLQSPQPPPAESLLTALLNE 137 + WLSL D+DPARF L A +G+ LQ+ P +++ +LL + Sbjct: 70 DQAVAWLSLAEEDDDPARFCRQLIEALGEAVPQLGDDAQTYLQNTMRVPVVAVIESLLGD 129 Query: 138 ISSDSEPSILVLDDYHVITAEPVNQAVAFLLEHLPPQMHLVIATREDXXXXXXXXXXXHQ 197 + + P +LVLDD H+++ + + L+++ PP + L + TR Sbjct: 130 LDRYARPLLLVLDDLHLVSNPDIFTGLNRLVQYAPPGLVLALGTRSQPALSLATWRAKGL 189 Query: 198 LTELRAADLRFNAAEAAEFLGGVMGLTLSAKDVMLLESRTEGWIAGLQLAALSMQGRNDT 257 L E+ +LR E E+L GL L + L +TEGW+ G+ L +L ++ + Sbjct: 190 LLEIGLEELRLGFEETREYLER-SGLYLDEPCLKALYGQTEGWVVGVHLVSLWLR-QQPQ 247 Query: 258 TGFIQSFTGSHKFVLDYLIEEVLQQQPASIQAFLQFTSVLDKMCGPLCDAVLGKDSEGAS 317 + G + V YL+ V ++ P +Q L V ++ G L +A+ G Sbjct: 248 VQEMALLDGDKQAVSAYLLAAVFERLPGDLQEALLALGVASQLSGDLANALTG------- 300 Query: 318 RSTGQRTLEYLEHANLFLIPLDNERRWYRYHHLFADLLRERLNQGFFPSEGGKEKTVSEL 377 R GQ LE LE LFL+PLD ER+WYR+H LFAD LR RL +L Sbjct: 301 RQDGQALLERLESMQLFLLPLDRERQWYRFHLLFADFLRNRLRD-------SDPDRFKQL 353 Query: 378 HLRASQWYEDNXXXXXXXXXXXXXXXXXXXXXLTEGEGMPLLFRGAVTPVLNWLQSLPEE 437 H AS W+ ++ L +G G+ L+ RG ++ + W + +P+E Sbjct: 354 HFNASLWFTNHHMPTFAIEHACAAEDPEMIAALVDGCGLELINRGQLSLIYRWRKHVPDE 413 Query: 438 ELDAIPSL 445 + P L Sbjct: 414 IAERYPIL 421 Score = 75.9 bits (185), Expect = 3e-13, Method: Compositional matrix adjust. Identities = 60/169 (35%), Positives = 84/169 (49%), Gaps = 20/169 (11%) Query: 749 ERLKGMILYAAALYKCGDNSGAAHTLAEAMRIAEPGGCIRSFVDEGPEAERLLR---GSE 805 +RL+ IL A + + G A L E + AE G F++EG +LL+ +E Sbjct: 750 QRLRLDILAALSYQRLGYQERANSLLGECLINAEREGVRSLFIEEGDGIRQLLQQLESTE 809 Query: 806 IPGEMLDYRRKLLAAFAAETPETLEILTSSQTGASRHHIRPDQPLFEKLSRRELEILQLI 865 + + R LL + + +P L E L+ RE E++ L Sbjct: 810 RQPALQTFIRGLLGIWPGQGVR-----------------KPQDALEEGLTEREREVVCLA 852 Query: 866 AQGLSNREIGDRMFLALSTVKGYNRNIFDKLQVSRRTEAIARARMLGLL 914 AQGLSN EIG R+ LAL TVK + NI++KL+V RT+AI RAR L LL Sbjct: 853 AQGLSNEEIGQRLSLALGTVKWHLHNIYEKLKVRNRTQAIRRARELSLL 901 >PA3420 [K] COG2909 ATP-dependent transcriptional regulator Length = 827 Score = 72.0 bits (175), Expect = 4e-12, Method: Compositional matrix adjust. Identities = 37/61 (60%), Positives = 49/61 (80%) Query: 854 LSRRELEILQLIAQGLSNREIGDRMFLALSTVKGYNRNIFDKLQVSRRTEAIARARMLGL 913 LS REL +L LIAQG SN+EIG+++F++L TVK + R I KL V+RRT+A+ARA+ LGL Sbjct: 766 LSCRELAVLGLIAQGCSNQEIGEQLFISLHTVKTHARRINGKLGVARRTQAVARAKALGL 825 Query: 914 L 914 L Sbjct: 826 L 826 >Cgl1963 [TK] COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Length = 210 Score = 70.5 bits (171), Expect = 1e-11, Method: Compositional matrix adjust. Identities = 37/80 (46%), Positives = 55/80 (68%), Gaps = 1/80 (1%) Query: 835 SQTGASRHHIRPDQPLFEKLSRRELEILQLIAQGLSNREIGDRMFLALSTVKGYNRNIFD 894 S+ AS+ R + P+ LS RE+E+L L+AQG SNREIG ++FL +TVK + ++F+ Sbjct: 132 SKQVASKIMGRMNNPM-TALSAREIEVLSLVAQGQSNREIGKKLFLTEATVKSHMGHVFN 190 Query: 895 KLQVSRRTEAIARARMLGLL 914 KL V+ RT A+A AR G++ Sbjct: 191 KLDVTSRTAAVAEARQRGII 210 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.319 0.133 0.384 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 58,973,293 Number of extensions: 2316314 Number of successful extensions: 11593 Number of sequences better than 1.0e-05: 35 Number of HSP's gapped: 11580 Number of HSP's successfully gapped: 38 Length of query: 914 Length of database: 38,378,431 Length adjustment: 116 Effective length of query: 798 Effective length of database: 24,999,687 Effective search space: 19949750226 Effective search space used: 19949750226 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 120 (50.8 bits)