BLASTP 2.2.18 [Mar-02-2008]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment: Altschul, Stephen F., 
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= 0530.0010.p
         (274 letters)

Database: COG 
           115,334 sequences; 38,378,431 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

BS_yqeM [QR] COG0500 SAM-dependent methyltransferases                  60   3e-09
SPy0312 [QR] COG0500 SAM-dependent methyltransferases                  56   5e-08
TM0938 [QR] COG0500 SAM-dependent methyltransferases                   56   7e-08
Cgl1261 [QR] COG0500 SAM-dependent methyltransferases                  55   1e-07
SP1743 [QR] COG0500 SAM-dependent methyltransferases                   52   7e-07

>BS_yqeM [QR] COG0500 SAM-dependent methyltransferases
          Length = 301

 Score = 60.5 bits (145), Expect = 3e-09,   Method: Compositional matrix adjust.
 Identities = 4/114 (3%), Positives = 17/114 (14%), Gaps = 5/114 (4%)

Query: 56  KWLSGVIPANGKILDLGCGPGLYAKRLSGMWYDVTGVDFSKRSIAYAKSQDAKTEYIYKN 115
                +                    +            +       K    +      +
Sbjct: 24  LLNKLLGQKISITSRKAQTTRHRIVGIHTEGAYQAIYVDTPGLHMEEKRAINRLMNKAAS 83

Query: 116 YLDIE----YTAMYNAVTLIYGDYAAL-TPDERKTLVEKVHKALKPGGLFILDV 164
               +       +         +       + +  ++  V+K         L  
Sbjct: 84  SSIGDVELVIFVVEGTRWTPDDEMVLNKLREGKAPVILAVNKVDNVQEKADLLP 137


>SPy0312 [QR] COG0500 SAM-dependent methyltransferases
          Length = 263

 Score = 56.2 bits (134), Expect = 5e-08,   Method: Compositional matrix adjust.
 Identities = 35/112 (31%), Positives = 56/112 (50%), Gaps = 7/112 (6%)

Query: 64  ANGKILDLGCGPGLYAKRLSGMWYDVTGVDFSKRSIAYAK----SQDAKTEYIYKNYLDI 119
              ++L+L CG G+ + R +   +DVTG+D S+  +A AK    S   K ++I  N LD+
Sbjct: 53  GRNRLLELACGTGIQSVRFAQAGFDVTGLDLSQDMLAIAKKRAQSAKKKIDFIQGNMLDL 112

Query: 120 EYTAMYNAVTLIYGDYAALTPDERKT--LVEKVHKALKPGGLFILDVFTEKQ 169
                ++ VT  Y D      DE     + ++V+  L   G+FI DV +  Q
Sbjct: 113 SQVGQFDFVT-CYSDSICYMQDEVDVGDVFKEVYDVLANDGIFIFDVHSTYQ 163


>TM0938 [QR] COG0500 SAM-dependent methyltransferases
          Length = 254

 Score = 55.8 bits (133), Expect = 7e-08,   Method: Compositional matrix adjust.
 Identities = 35/107 (32%), Positives = 60/107 (56%), Gaps = 9/107 (8%)

Query: 67  KILDLGCGPGLYAKRLSGMWYDVTGVDFSKRSIAYAKSQDAKTE-----YIYKNYLDIEY 121
           K+LD+ CG G +A  ++   + V GVD S   + +A+ + AK E     ++ K+  ++++
Sbjct: 41  KVLDVACGEGTFAVEIAKQGFKVVGVDLSSEMLKFARKR-AKEESISVVFLKKDMRELDF 99

Query: 122 TAMYNAVTLIYG--DYAALTPDERKTLVEKVHKALKPGGLFILDVFT 166
              ++ VT  +   +Y     D +KT  EKVH+ALK GG F+ D+ T
Sbjct: 100 HEEFDIVTCWFDSLNYLLDYKDLKKTF-EKVHEALKTGGAFLFDMNT 145


>Cgl1261 [QR] COG0500 SAM-dependent methyltransferases
          Length = 201

 Score = 55.1 bits (131), Expect = 1e-07,   Method: Compositional matrix adjust.
 Identities = 39/135 (28%), Positives = 62/135 (45%), Gaps = 10/135 (7%)

Query: 52  NRSVKWLSGVIPANGKILDLGCGPGLYAKRLSGMWYDVTGVDFSKRSIAYAKSQDAKTEY 111
           N+++    G  PA G  LD+GCG G     LS   Y  TG+DF+  ++  AK      E 
Sbjct: 38  NQALIAYLGEEPAEGTALDIGCGEGADLVWLSSKGYVTTGIDFAPTAVKRAKQNAPSAEV 97

Query: 112 IYKNYLD--IEYTAMYNAVTLIYGDYAALTPDERKTLVEKVHKALKPGGLFILDVFTEKQ 169
           +  ++ +  IE    ++ V+  YG   A       T V ++   + PGG  +   FT   
Sbjct: 98  LLVSFTEFAIESGRQFDLVSCSYGQIPA-----NDTSVAQLENLVAPGGTLL---FTHHD 149

Query: 170 FENKKSSTSWALCTN 184
           FE++ ++T   L  N
Sbjct: 150 FESESAATPKWLSEN 164


>SP1743 [QR] COG0500 SAM-dependent methyltransferases
          Length = 248

 Score = 52.4 bits (124), Expect = 7e-07,   Method: Compositional matrix adjust.
 Identities = 36/109 (33%), Positives = 54/109 (49%), Gaps = 7/109 (6%)

Query: 67  KILDLGCGPGLYAKRLSGMWYDVTGVDFSKRSIAYAK----SQDAKTEYIYKNYLDIEYT 122
           K+L+L CG G+ + R S   +DVTG+D S   +  A+    S   K  +I  N L++   
Sbjct: 41  KLLELACGTGIQSVRFSQAGFDVTGLDLSADMLKIAEKRATSAKQKIAFIEGNMLNLSKA 100

Query: 123 AMYNAVTLIYGDYAALTPDERKT--LVEKVHKALKPGGLFILDVFTEKQ 169
             Y+ VT  Y D      DE +   + + V+ AL   G+FI DV +  Q
Sbjct: 101 GKYDFVT-CYSDSICYMQDEVEVGDVFKDVYNALNEEGVFIFDVHSTYQ 148


  Database: COG
    Posted date:  Aug 3, 2010  9:58 AM
  Number of letters in database: 38,378,431
  Number of sequences in database:  115,334
  
Lambda     K      H
   0.318    0.136    0.429 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 115334
Number of Hits to DB: 22,342,142
Number of extensions: 975608
Number of successful extensions: 3181
Number of sequences better than 1.0e-05: 13
Number of HSP's gapped: 3201
Number of HSP's successfully gapped: 13
Length of query: 274
Length of database: 38,378,431
Length adjustment: 105
Effective length of query: 169
Effective length of database: 26,268,361
Effective search space: 4439353009
Effective search space used: 4439353009
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 115 (48.9 bits)