BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0523.0038.p (605 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value BS_ydaO [E] COG0531 Amino acid transporters 579 e-165 lin2235 [E] COG0531 Amino acid transporters 565 e-161 SA2229 [E] COG0531 Amino acid transporters 532 e-151 CAP0027 [E] COG0531 Amino acid transporters 412 e-115 CAC0272 [E] COG0531 Amino acid transporters 412 e-115 >BS_ydaO [E] COG0531 Amino acid transporters Length = 311 Score = 579 bits (1493), Expect = e-165, Method: Compositional matrix adjust. Identities = 0/608 (0%), Positives = 0/608 (0%), Gaps = 4/608 (0%) Query: 1 MVSKVKRLLIGRPMKSNELDHEKLSKXXXXXXXXXXXXXXXXYGTEQILIVLVAAGFTAI 60 M + + + + + Sbjct: 1 MQENQQITKKEQYNLNKLQKRLRRNVGEAIADFNMIEEGDRIMVCLSGGKDSYTMLEILR 60 Query: 61 WYSXXXXXXXXXXXXXXXXSYRQTIFAYPQGGGAYIVAKSNLGVPTGLLAGGSLLVDYIL 120 + + + + + Sbjct: 61 NLQQSAPINFSLVAVNLDQKQPGFPEHVLPEYLEKLGVEYKIVEENTYGIVKEKIPEGKT 120 Query: 121 TVAVSASAGTDAITSAFPSLHNHSXXXXXXXXXXXXXXNLRGVTESASFIAIPVYLFVAS 180 T ++ + + L L P + Sbjct: 121 TCSLCSRLRRGILYRTATELGATKIALGHHRDDILQTLFLNMFYGGKMKGMPPKLMSDDG 180 Query: 181 IFILIIAGVFKYATGGAH--ANVPEIGSAVSNVSLFLLLKAFSSGCSALTGVEAVSNAIP 238 I+I + + L+ + I Sbjct: 181 KHIVIRPLAYCREKDIQRFADAKAFPIIPCNLCGSQPNLQRQVIADMLRDWDKRYPGRIE 240 Query: 239 NFKAPAEKNAAKXXXXXXXXXXXXXXXXXXXAYWYGITPDEKATVVSQIAESTFGRGGLY 298 + + + D + + Sbjct: 241 TMFSAMQNVVPSHLCDTNLFDFKGITHGSEVVNGGDLAFDREEIPLQPACWQPEEDENQL 300 Query: 299 FFIQGITAVILFLAANTAYSAFPLLAFMFAKDKYLPHAFMVRGDRLGFSNGIIFLGVLSA 358 Sbjct: 301 360 Query: 359 LLVTAFHGNTESLIPLYAVGVFIPFTLSQLGMMVHWCKTKPKAWQNKFAVNTVGMXXXXX 418 Sbjct: 361 420 Query: 419 XXXXXXXXKFSSVWMAFIFLPVVMFVFHRIHHHYLNTADQLRICPATDKPCIKGSXXXXX 478 Sbjct: 421 - 479 Query: 479 XXXXXXXXLHSISYAKSLTDNVVAVYVGFDEEEISKMEQKWEEWNPGVRLIVLRSRYRSI 538 Sbjct: 480 539 Query: 539 LRPLVKFIDTVEWKTASTD-HITVLIPQFITKHWWQAVLHNQTSLFIRSYLMNQKDIVVA 597 Sbjct: 540 599 Query: 598 TVPYHLHK 605 Sbjct: 600 607 >lin2235 [E] COG0531 Amino acid transporters Length = 607 Score = 565 bits (1457), Expect = e-161, Method: Compositional matrix adjust. Identities = 290/607 (47%), Positives = 378/607 (62%), Gaps = 2/607 (0%) Query: 1 MVSKVKRLLIGRPMKSNELDHEKLSKXXXXXXXXXXXXXXXXYGTEQILIVLVAAGFTAI 60 M S +KRLLIGRP+K++E +KL K YGTEQIL+VLV A+ Sbjct: 1 MASPLKRLLIGRPLKTSEAGDQKLGKLKALAVLSSDALSSIAYGTEQILLVLVTVSAAAM 60 Query: 61 WYSXXXXXXXXXXXXXXXXSYRQTIFAYPQGGGAYIVAKSNLGVPTGLLAGGSLLVDYIL 120 WYS SY+Q I++YP GGGAYIV++ NLG GL+AGGSLLVDY+L Sbjct: 61 WYSLPIALCVLVLLFALNLSYKQIIYSYPHGGGAYIVSRENLGNNAGLIAGGSLLVDYML 120 Query: 121 TVAVSASAGTDAITSAFPSLHNHSXXXXXXXXXXXXXXNLRGVTESASFIAIPVYLFVAS 180 TVAVS S+GTDAI SA PSL+ + NLRG+TESAS +AIPVYLFV S Sbjct: 121 TVAVSVSSGTDAIVSAVPSLYPFAVPIAVLLVVGVTIINLRGITESASLLAIPVYLFVFS 180 Query: 181 IFILIIAGVFKYATG-GAHANVPEIGSAVSNVSLFLLLKAFSSGCSALTGVEAVSNAIPN 239 I LI G+FK TG A +G+ V V++FLLL+AF+SG ++LTG+EA+SNA+P Sbjct: 181 IIALIFTGLFKVLTGMDASHETAAVGTHVQGVTIFLLLRAFASGSASLTGIEAISNAVPL 240 Query: 240 FKAPAEKNAAKXXXXXXXXXXXXXXXXXXXAYWYGITPDEKATVVSQIAESTFGRGGLYF 299 FK P KNAAK A+ YG P+ K TV+SQIAE+ FGR +++ Sbjct: 241 FKEPRPKNAAKTLTLMAGLLGFFFVGITVLAFVYGTVPELKVTVLSQIAENVFGRNFMFY 300 Query: 300 FIQGITAVILFLAANTAYSAFPLLAFMFAKDKYLPHAFMVRGDRLGFSNGIIFLGVLSAL 359 FIQ TA+IL LAANT +SAFP+LAF AKDK++P ++ RGDRLG+SNGII L V S L Sbjct: 301 FIQATTALILVLAANTGFSAFPMLAFNLAKDKFMPRMYLARGDRLGYSNGIITLAVGSIL 360 Query: 360 LVTAFHGNTESLIPLYAVGVFIPFTLSQLGMMVHWCKTKPKAWQNKFAVNTVGMXXXXXX 419 L+ F G TE LIPLY+VGVFIPFTLSQ GM+V W K +PK W+ + N +G Sbjct: 361 LIILFKGKTELLIPLYSVGVFIPFTLSQTGMIVKWWKQRPKGWKKSLSANLLGASISFTV 420 Query: 420 XXXXXXXKFSSVWMAFIFLPVVMFVFHRIHHHYLNTADQLRICPATDKPCIKGSXXXXXX 479 + SVW F+F+P++++VFHR HHY QLRI D P KG+ Sbjct: 421 LLVLFLTRIESVWPVFVFMPIMIYVFHRTRHHYRKVGPQLRIDETMDLPDFKGNAVIICV 480 Query: 480 XXXXXXXLHSISYAKSLTDNVVAVYVGFDEEEISKMEQKWEEWNPGVRLIVLRSRYRSIL 539 ++ YAKS+ D V+AV++ D+++ + ++W +P VR+ L S YRSI Sbjct: 481 SDTTKVVEGALQYAKSIGDTVIAVHISIDKKQEKEFVERWNRVHPEVRMANLYSPYRSIS 540 Query: 540 RPLVKFIDTVEWKTASTDH-ITVLIPQFITKHWWQAVLHNQTSLFIRSYLMNQKDIVVAT 598 PL+KFIDT + K ++ +TVLIPQFI + WQ VLHNQTSL IR+ L+ ++D+VV+T Sbjct: 541 DPLMKFIDTAKQKADQDNYSLTVLIPQFIPRKGWQNVLHNQTSLLIRTRLLMKRDVVVST 600 Query: 599 VPYHLHK 605 PYHL + Sbjct: 601 YPYHLKE 607 >SA2229 [E] COG0531 Amino acid transporters Length = 609 Score = 532 bits (1371), Expect = e-151, Method: Compositional matrix adjust. Identities = 279/609 (45%), Positives = 369/609 (60%), Gaps = 4/609 (0%) Query: 1 MVSKVKRLLIGRPMKSNELDHEKLSKXXXXXXXXXXXXXXXXYGTEQILIVLVAAGFTAI 60 M ++ KRL+IG+P K+ EL EK+SK YG EQILI L G A Sbjct: 1 MFNQFKRLIIGQPKKNRELKDEKISKFKGLAILSSDALSSVAYGPEQILITLSVVGAVAT 60 Query: 61 WYSXXXXXXXXXXXXXXXXSYRQTIFAYPQGGGAYIVAKSNLGVPTGLLAGGSLLVDYIL 120 WY+ SYRQ I+AYP+GGGAY+V+K+NLG GLLAGGSLLVDYIL Sbjct: 61 WYTLPIAGAVLILLAALIMSYRQIIYAYPKGGGAYMVSKTNLGEKWGLLAGGSLLVDYIL 120 Query: 121 TVAVSASAGTDAITSAFPSLHNHSXXXXXXXXXXXXXXNLRGVTESASFIAIPVYLFVAS 180 TVAVS S+G DA +AFPSL+ H NLRG+TESA+ ++ PVYLF+ Sbjct: 121 TVAVSISSGADAFVAAFPSLYGHKVLIACLLVLFILILNLRGLTESATVLSYPVYLFIIG 180 Query: 181 IFILIIAGVFKYATGGAHANV-PEIGSAVSNVSLFLLLKAFSSGCSALTGVEAVSNAIPN 239 + ILI G F+ ATG ++ +G+AV V+LFLLLKAFSSG S+LTGVEA+SNA+ N Sbjct: 181 LVILIFIGTFRVATGDIQPHMHASVGTAVPGVTLFLLLKAFSSGASSLTGVEAISNAVTN 240 Query: 240 FKAPAEKNAAKXXXXXXXXXXXXXXXXXXXAYWYGITPDEKATVVSQIAESTFGRGGLYF 299 F+ P+ NA K AY YGI P + TV+SQ+A FG ++ Sbjct: 241 FREPSANNAVKTLIAMGSILAFLLVGIVGLAYVYGIMPQTETTVLSQLAMQIFGDNAAFY 300 Query: 300 FIQGITAVILFLAANTAYSAFPLLAFMFAKDKYLPHAFMVRGDRLGFSNGIIFLGVLSAL 359 F+Q T +IL LAANT ++AFP+LA +KDKY+P F VRGDRLG+SN II LGVL+ + Sbjct: 301 FVQATTVMILVLAANTGFTAFPMLAASMSKDKYMPRMFTVRGDRLGYSNSIIILGVLAII 360 Query: 360 LVTAFHGNTESLIPLYAVGVFIPFTLSQLGMMVHWCKTKPKAWQNKFAVNTVGMXXXXXX 419 L+ F G TE LIPLYAVGVFIPFTL+Q GM++ W +PK W +K +VN +G Sbjct: 361 LIIVFDGMTEDLIPLYAVGVFIPFTLAQFGMVIKWIHERPKNWLSKLSVNLLGGIVTFIV 420 Query: 420 XXXXXXXKFSSVWMAFIFLPVVMFVFHRIHHHYLNTADQLR-ICPATDKPCIKGSXXXXX 478 KFS VW IFLP V+ F +I+ HY + A+QLR + + + Sbjct: 421 FMILLITKFSQVWPILIFLPFVVIFFLKINKHYRDIAEQLRSDIDVLNVDVVDRNLAIVP 480 Query: 479 XXXXXXXXLHSISYAKSLTDN-VVAVYVGFDEEEISKMEQKWEEWNPGVRLIVLRSRYRS 537 SI YA+ L +N V+AV+V F +E+ ++KW+ P VRL++L S YRS Sbjct: 481 ITSITTAVDKSIYYAQMLANNDVIAVHVSFGDEDEKAFQEKWKRHFPDVRLVILHSEYRS 540 Query: 538 ILRPLVKFIDTVEWKTASTDH-ITVLIPQFITKHWWQAVLHNQTSLFIRSYLMNQKDIVV 596 I+RP+ +FID + K ++ ITV+IP+FITK W +LHNQTSL ++ YL+ QK++ V Sbjct: 541 IIRPISRFIDKINRKANDQNYMITVVIPEFITKKRWHNLLHNQTSLRMKLYLIYQKNVNV 600 Query: 597 ATVPYHLHK 605 T+P+ L K Sbjct: 601 CTIPFKLKK 609 >CAP0027 [E] COG0531 Amino acid transporters Length = 615 Score = 412 bits (1060), Expect = e-115, Method: Compositional matrix adjust. Identities = 237/613 (38%), Positives = 345/613 (56%), Gaps = 12/613 (1%) Query: 1 MVSKVKRLLIGRPMKSNELDHEKLSKXXXXXXXXXXXXXXXXYGTEQILIVL-VAAGFTA 59 M+ K +L+G+P+ + + HEK + Y E+ILIVL V G A Sbjct: 1 MMDKFLDILLGKPLANEQGSHEKFNIPFGLAVMASDAISSVAYAAEEILIVLIVVLGLQA 60 Query: 60 IWYSXXXXXXXXXXXXXXXXSYRQTIFAYPQGGGAYIVAKSNLGVPTGLLAGGSLLVDYI 119 + SY Q I AYPQGGGAYIVAK N+G GL+AG +LL+DYI Sbjct: 61 YTWLSIVALMIIGLLAILTVSYLQIIRAYPQGGGAYIVAKENIGTVPGLVAGAALLIDYI 120 Query: 120 LTVAVSASAGTDAITSAFPSLHNHSXXXXXXXXXXXXXXNLRGVTESASFIAIPVYLFVA 179 LTVAVSASAG AI SAFP L N+ NLRGV+ES+ ++P Y+FV Sbjct: 121 LTVAVSASAGGAAILSAFPGLLNYKVLIVIVFIVVLTILNLRGVSESSKIFSLPTYIFVF 180 Query: 180 SIFILIIAGVFKYATGGAHANVPEIGSAV----SNVSLFLLLKAFSSGCSALTGVEAVSN 235 + +I+ G+FKYA G AN ++ V ++VS+FL+L+AFS GCSALTG+EAVSN Sbjct: 181 GMMFMIVFGIFKYAFWGGAAN--QVNKVVLKQTADVSIFLILRAFSQGCSALTGLEAVSN 238 Query: 236 AIPNFKAPAEKNAAKXXXXXXXXXXXXXXXXXXXAYWYGITPDEKATVVSQIAESTFGRG 295 ++PNFK P+++NA A Y P E TV++QIAE FGR Sbjct: 239 SVPNFKEPSQRNAKIVMILLSSIILFIFGGSSILANLYRAVPGENVTVLAQIAEGVFGRN 298 Query: 296 GLYFFIQGITAVILFLAANTAYSAFPLLAFMFAKDKYLPHAFMVRGDRLGFSNGIIFLGV 355 +++ IQ TA+IL +A NTA++ FP+L ++ A+D ++P F RG RL FS GI+ L V Sbjct: 299 FMFYLIQVSTAIILLMACNTAFTGFPMLMYVVARDGFVPRQFTHRGKRLSFSIGIVSLSV 358 Query: 356 LSALLVTAFHGNTESLIPLYAVGVFIPFTLSQLGMMVHWCKTKPKAWQNKFAVNTVGMXX 415 ++ +LV F T +L+PLY+VGVF+ FTL+Q GM++HW + K + W+ + +N G Sbjct: 359 IAGILVIVFKAVTHNLLPLYSVGVFMSFTLAQTGMVIHWRQGKERNWRIRALINGFGAVV 418 Query: 416 XXXXXXXXXXXKFSS-VWMAFIFLPVVMFVFHRIHHHYLNTADQLRI----CPATDKPCI 470 KF + W+ I +P+++F+ I HY A+QLR A D Sbjct: 419 TTITTGIIAYEKFEAGAWIVIILIPILVFIMLAIKRHYNIVAEQLRAHLKDYKAADLQKK 478 Query: 471 KGSXXXXXXXXXXXXXLHSISYAKSLTDNVVAVYVGFDEEEISKMEQKWEEWNPGVRLIV 530 L ++ YAKS+TDNV+A+ + +E++ K++ W E + + L+ Sbjct: 479 FTHLAVVPIASLNKASLSALQYAKSVTDNVIALNISISKEQMEKLKASWSELDTDIVLVS 538 Query: 531 LRSRYRSILRPLVKFIDTVEWKTASTDHITVLIPQFITKHWWQAVLHNQTSLFIRSYLMN 590 S YR I+ PL++ ID + + + + ITV++PQFIT WW +LHN T +F+R ++ Sbjct: 539 KYSPYRHIVTPLLQSIDDIASRASDDEKITVVLPQFITHKWWGNLLHNNTGIFLRESILR 598 Query: 591 QKDIVVATVPYHL 603 K+++V+T PYHL Sbjct: 599 NKNVIVSTYPYHL 611 >CAC0272 [E] COG0531 Amino acid transporters Length = 620 Score = 412 bits (1059), Expect = e-115, Method: Compositional matrix adjust. Identities = 247/616 (40%), Positives = 342/616 (55%), Gaps = 17/616 (2%) Query: 1 MVSKVKRLLIGRPMKSNELDHEKLSKXXXXXXXXXXXXXXXXYGTEQILIVLVAA-GFTA 59 MV+K LLI RP+ + + EK + Y +++IL+VLV G + Sbjct: 1 MVNKFFDLLICRPLANEQSSSEKYNVPFGLAVMASDAISSVAYASQEILLVLVPIIGAAS 60 Query: 60 IWYSXXXXXXXXXXXXXXXXSYRQTIFAYPQGGGAYIVAKSNLGVPTGLLAGGSLLVDYI 119 + SY Q I AYPQGGGAYIVAK NLGV GL+AG SLL+DYI Sbjct: 61 YAWLGKASLMIIGLLLILTVSYVQIIKAYPQGGGAYIVAKENLGVKPGLVAGASLLLDYI 120 Query: 120 LTVAVSASAGTDAITSAFPSLHNHSXXXXXXXXXXXXXXNLRGVTESASFIAIPVYLFVA 179 LTVAVSAS+G AITSAFPSL HS NLRGV+ESA +IP YLF+ Sbjct: 121 LTVAVSASSGVAAITSAFPSLVPHSVLLAVVLIIILTILNLRGVSESAKMFSIPTYLFIF 180 Query: 180 SIFILIIAGVFKYATGGA------HANVPEIGSAVSNVSLFLLLKAFSSGCSALTGVEAV 233 S+ +II G+ KY GA H + +G +VS+FL+LKAFSSGCSALTG+EAV Sbjct: 181 SMIFMIIFGIAKYIIYGAPSMHMIHQTLKPMG----DVSIFLILKAFSSGCSALTGLEAV 236 Query: 234 SNAIPNFKAPAEKNAAKXXXXXXXXXXXXXXXXXXXAYWYGITPDEKATVVSQIAESTF- 292 SN++PNFK P +KNA A +YG P++ TV++QIA F Sbjct: 237 SNSVPNFKEPGQKNATIVMVLLTLCIFVIFGGSSLLARFYGAIPNDNVTVLAQIAYGVFS 296 Query: 293 GRGGLYFFIQGITAVILFLAANTAYSAFPLLAFMFAKDKYLPHAFMVRGDRLGFSNGIIF 352 G+ +++ +Q TA+IL +A NT+++ FP+L + A+D Y P +F RG RL FSNGI+F Sbjct: 297 GKTFMFYVVQFTTAIILIMACNTSFTGFPMLMSVIARDGYAPRSFATRGKRLSFSNGIVF 356 Query: 353 LGVLSALLVTAFHGNTESLIPLYAVGVFIPFTLSQLGMMVHWCKTKPKAWQNKFAVNTVG 412 L +++ +LV F +T LIPLY+VGVF+ FTL+Q GM++HW KT K + +N G Sbjct: 357 LSIIAGILVIIFKADTHLLIPLYSVGVFLSFTLAQTGMVIHWNKTNEKGKNTRKLINGFG 416 Query: 413 MXXXXXXXXXXXXXKF-SSVWMAFIFLPVVMFVFHRIHHHYLNTADQLRICPATDKPCIK 471 KF S W+ I +P+++ F I HY A LR K C Sbjct: 417 AAITLLTTGVIVYEKFLSGAWVIIILVPIIVLGFLHIKKHYNYVARGLRADEEYVKNCGI 476 Query: 472 GSX----XXXXXXXXXXXXLHSISYAKSLTDNVVAVYVGFDEEEISKMEQKWEEWNPGVR 527 G L ++ YA+SLT +V+A+ V ++E + K++ KWEE N + Sbjct: 477 GQTYNHLIIVPIASLNKATLGALKYARSLTSDVIALNVSPNKEYMDKLKHKWEELNTDIL 536 Query: 528 LIVLRSRYRSILRPLVKFIDTVEWKTASTDHITVLIPQFITKHWWQAVLHNQTSLFIRSY 587 L+ S YR+I+ PL+++I + + ITV++PQFIT+ +LHN TS +R Sbjct: 537 LVSKYSPYRAIVTPLIEYIGVISKAAVPDEKITVVLPQFITRDKSGQILHNHTSFLLREA 596 Query: 588 LMNQKDIVVATVPYHL 603 L+ +IVV+T P+HL Sbjct: 597 LLRYDNIVVSTYPFHL 612 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.324 0.137 0.415 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 35,234,661 Number of extensions: 1232513 Number of successful extensions: 4672 Number of sequences better than 1.0e-05: 7 Number of HSP's gapped: 4634 Number of HSP's successfully gapped: 7 Length of query: 605 Length of database: 38,378,431 Length adjustment: 112 Effective length of query: 493 Effective length of database: 25,461,023 Effective search space: 12552284339 Effective search space used: 12552284339 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 15 ( 7.0 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 40 (21.6 bits) S2: 119 (50.4 bits)