BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0523.0005.p (299 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value CAC0023 [K] COG0583 Transcriptional regulator 217 2e-56 BS_gltR [K] COG0583 Transcriptional regulator 149 7e-36 RSc0214 [K] COG0583 Transcriptional regulator 132 6e-31 mll2048 [K] COG0583 Transcriptional regulator 123 3e-28 sll0030 [K] COG0583 Transcriptional regulator 114 2e-25 >CAC0023 [K] COG0583 Transcriptional regulator Length = 299 Score = 217 bits (552), Expect = 2e-56, Method: Compositional matrix adjust. Identities = 111/275 (40%), Positives = 166/275 (60%) Query: 5 SFTRAAQKLDYAQSSITAQIQALEAELGQPLFDRISKKIILTDAGRRLLPYAQEISRMHT 64 SFT AA L+YAQS++T QI+ LE EL LF+RI KK+ LT G++LLPYA+++ ++ Sbjct: 17 SFTEAAHSLNYAQSTVTTQIKILEEELQIKLFERIGKKVTLTYEGKKLLPYAKQMIKLSN 76 Query: 65 LAEVALRSDTELSGALRIGAPESLAAFRLPGIIKEFRGRYPQVQITLKPGACWELTEFVR 124 + + D + SG L IGA ESL RLP I+KE+R YP V+++LK G+C + F++ Sbjct: 77 EIKKVVLDDEKPSGTLTIGAAESLCVIRLPEILKEYRRLYPDVEVSLKFGSCADFRHFLK 136 Query: 125 SGELDLVFLLQPETEYKDLHTETLIQEAMALVAPLGHPLLELAEVLPHHLKDETILHTET 184 +D+ F L + + + +E E M L+A HPL++ ++ P + +E ++ TE Sbjct: 137 DNIIDVAFSLGTKIDSNEFISEVEFDEPMILLAYPDHPLVKKEKIYPEDIVEEPLVLTEM 196 Query: 185 GCTYRTLFERHLNSHGVFPDPKLEFWSVEAIKQCVTAGLGLSFLPMITVQSELAEGKLAR 244 GC+YR FE L S+ + P LE SV+AIKQ + LG++ LP + V+ E+ GKL Sbjct: 197 GCSYRAAFENILRSYNIKPKLVLETGSVQAIKQFTMSRLGITLLPKVAVEEEIKNGKLIP 256 Query: 245 LHWNDESQRVATQIAYHHKKWKSPALAEFLSTIQK 279 L+W + +Q+ YH KW SPAL FL +K Sbjct: 257 LNWCGPDFGIISQVLYHKDKWISPALNAFLKLSKK 291 >BS_gltR [K] COG0583 Transcriptional regulator Length = 296 Score = 149 bits (375), Expect = 7e-36, Method: Compositional matrix adjust. Identities = 95/279 (34%), Positives = 150/279 (53%), Gaps = 9/279 (3%) Query: 4 GSFTRAAQKLDYAQSSITAQIQALEAELGQPLFDRISKKIILTDAGRRLLPYAQEISRMH 63 GS ++AA L+YAQS++T +IQ LE +L LF R S+ I LT G+ L+ Y+++I +H Sbjct: 16 GSISKAALTLNYAQSNVTNKIQQLENDLQTKLFYRHSRGITLTPPGQILVSYSEKI--LH 73 Query: 64 TL--AEVALRSDTELSGALRIGAPESLAAFRLPGIIKEFRGRYPQVQITLKPGACWELTE 121 T+ A A+ + SG LRIG+ E+ AA LP ++ + YP V + L G + + Sbjct: 74 TIEEARAAMGESSAPSGPLRIGSMETTAAVWLPQLLAHYNNLYPNVDLNLVTGPTEQQIQ 133 Query: 122 FVRSGELDLVFLLQPETEYKDLHTETLIQEAMALVAPLGHPLLELAEVLPHHLKDETILH 181 V EL+ F+ P E+ DL E ++ E M LV HP++ + ++ +T++ Sbjct: 134 AVLHYELNGAFISGP-IEHPDLVQEKVLDEEMVLVTSASHPVISSIQ----DVQTQTMVV 188 Query: 182 TETGCTYRTLFERHLNSHGVFPDPKLEFWSVEAIKQCVTAGLGLSFLPMITVQSELAEGK 241 GC+YR L G+ P +EF +EAI CV+AGLG+S LP + S EG+ Sbjct: 189 FRKGCSYRAKLNHILQEEGLLPIKLMEFGILEAIIGCVSAGLGISLLPRSIIASHEKEGR 248 Query: 242 LARLHWNDESQRVATQIAYHHKKWKSPALAEFLSTIQKH 280 + +D+ V+T +PAL+ FL+ ++ H Sbjct: 249 IRSHTISDKYSFVSTMFIRRKDTLITPALSAFLTHMRDH 287 >RSc0214 [K] COG0583 Transcriptional regulator Length = 288 Score = 132 bits (332), Expect = 6e-31, Method: Compositional matrix adjust. Identities = 85/239 (35%), Positives = 129/239 (53%), Gaps = 8/239 (3%) Query: 2 ETGSFTRAAQKLDYAQSSITAQIQALEAELGQPLFDRISKKIILTDAGRRLLPYAQEISR 61 + GS T+AA++L+ QS++T +++ LE LG LF R ++ L+ G RL YA+ + R Sbjct: 17 DLGSITQAARQLNRVQSNVTTRVKNLEERLGVKLFLRHGNRLTLSADGERLRGYAERLLR 76 Query: 62 MHTLAEVALRSDTELSGALRIGAPESLAAFRLPGIIKEFRGRYPQVQITLKPGACWELTE 121 + AE A+ G L++G ES AA RLP ++ +F RYP V I L G+ +L + Sbjct: 77 LSAEAESAMLVRAP-QGTLKLGTLESTAAARLPPVLSQFHRRYPDVLIELVTGSSAKLLD 135 Query: 122 FVRSGELDLVFLLQPETEYKDLHTETLIQEAMALVAPLGHPLLELAEVLPH-HLKDETIL 180 V+ E+D + +P L T+ E + L+APL VL H HL+ T++ Sbjct: 136 MVQRYEVDAALISEP-FHAPGLATQEAFDEVLVLIAPL-----TATHVLSHDHLQRCTVI 189 Query: 181 HTETGCTYRTLFERHLNSHGVFPDPKLEFWSVEAIKQCVTAGLGLSFLPMITVQSELAE 239 GC+YR +FE L S+G+ P LE S AI CV AG G+ +P +++ AE Sbjct: 190 AFSAGCSYRRIFEEWLASNGIAPARILELASYHAIVACVAAGTGIGIMPRSVLKAVHAE 248 >mll2048 [K] COG0583 Transcriptional regulator Length = 329 Score = 123 bits (309), Expect = 3e-28, Method: Compositional matrix adjust. Identities = 91/291 (31%), Positives = 135/291 (46%), Gaps = 16/291 (5%) Query: 5 SFTRAAQKLDYAQSSITAQIQALEAELGQPLFDRISKKIILTDAGRRLLPYAQEISRMHT 64 + TRAA+ + AQSS++ QIQ LEAELG LF R + LT AG L+P A+E+ R+ Sbjct: 17 NITRAAEAVHLAQSSVSDQIQTLEAELGAALFTRSKSGLELTPAGLALMPIAEELLRLDG 76 Query: 65 -LAEVALRSDTELSGALRIGAPESLAAFRLPGIIKEFRGRYPQVQITLKPGACWELTEFV 123 L + SGAL IGA E++AA RL + F+ +P + + +K L + Sbjct: 77 EARAAVLAAAGRTSGALTIGALETIAAARLAPWLPGFQAGHPDITVRMKVADSGTLRRLL 136 Query: 124 RSGELDLVFLLQPETEYKD-----LHTETLIQEAMALVAPLGHPLLELAEVLPHHLKDET 178 G++D+ F + + L T+ E + LVA G L P L D Sbjct: 137 EDGDIDVAFCFERRDGARGAADGRLARRTIGAEPLVLVAAPGQAL------APGGLADLA 190 Query: 179 ILH---TETGCTYRTLFERHLNSHGVF-PDPKLEFWSVEAIKQCVTAGLGLSFLPMITVQ 234 L TE GC YR + + + P P E S+ AI + V G GL +P + V Sbjct: 191 ALRFVATEPGCIYRHMLDTAFAEADMAPPKPAAEVGSIGAIARLVATGAGLGLIPRLAVS 250 Query: 235 SELAEGKLARLHWNDESQRVATQIAYHHKKWKSPALAEFLSTIQKHAAEWR 285 LA G+L L W + + + ++ + PAL + L+ + A R Sbjct: 251 GALARGELVELPWPGRMRPAPLTMVWRRRRIQPPALRQLLAAARDTLAPER 301 >sll0030 [K] COG0583 Transcriptional regulator Length = 304 Score = 114 bits (285), Expect = 2e-25, Method: Compositional matrix adjust. Identities = 82/279 (29%), Positives = 144/279 (51%), Gaps = 3/279 (1%) Query: 3 TGSFTRAAQKLDYAQSSITAQIQALEAELGQPLFDRISKKIILTDAGRRLLPYAQEI-SR 61 TGSFT+AA++L Q +++ Q++ L +G PL+++I +KI LT+AG+ +L ++ I S Sbjct: 18 TGSFTKAAEELFLTQPTVSQQMKQLTKAIGVPLYEQIGRKIYLTEAGQAVLDASKNITSC 77 Query: 62 MHTLAEVALRSDTELSGALRIGAPESLAAFRLPGIIKEFRGRYPQVQITLKPGACWELTE 121 + L EV G LR+ A + + +P ++ EFR +YP + I+L+ G ++ E Sbjct: 78 LDQLQEVIADLQGLKKGNLRL-ATITTGKYFVPRLLGEFRQQYPGISISLQIGNRQQILE 136 Query: 122 FVRSGELDLVFLLQPETEYKDLHTETLIQEAMALVAPLGHPLLELAEVLPHHLKDETILH 181 + + DL FL +P + D++ ++ + ++A HPL++ ++ L +E ++ Sbjct: 137 RLANNLDDLYFLGKPPSNL-DINIRHFLENPLVVIASRQHPLVKEKKISLERLVNEPLIM 195 Query: 182 TETGCTYRTLFERHLNSHGVFPDPKLEFWSVEAIKQCVTAGLGLSFLPMITVQSELAEGK 241 E+G R E + + + + ++E S EAIKQ V GLG+S L + ++ E G Sbjct: 196 RESGSGTRMAVEEFFSENRLKMNVEMEISSNEAIKQAVYGGLGISILSLYSLALEGINGP 255 Query: 242 LARLHWNDESQRVATQIAYHHKKWKSPALAEFLSTIQKH 280 LA L + I Y K S FL + H Sbjct: 256 LAVLDVEGFPLQKHWYIIYQKSKQLSIVAQTFLDYLFAH 294 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.319 0.133 0.391 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 20,974,016 Number of extensions: 779332 Number of successful extensions: 3713 Number of sequences better than 1.0e-05: 1500 Number of HSP's gapped: 3611 Number of HSP's successfully gapped: 1500 Length of query: 299 Length of database: 38,378,431 Length adjustment: 106 Effective length of query: 193 Effective length of database: 26,153,027 Effective search space: 5047534211 Effective search space used: 5047534211 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 115 (48.9 bits)