BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0521.0006.p (234 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value CAC0564 [TK] COG0745 Response regulators consisting of a CheY-li... 214 1e-55 BH1153 [TK] COG0745 Response regulators consisting of a CheY-lik... 209 4e-54 lin2516 [TK] COG0745 Response regulators consisting of a CheY-li... 192 4e-49 BS_phoP [TK] COG0745 Response regulators consisting of a CheY-li... 187 9e-48 lin2644 [TK] COG0745 Response regulators consisting of a CheY-li... 185 5e-47 >CAC0564 [TK] COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Length = 233 Score = 214 bits (545), Expect = 1e-55, Method: Compositional matrix adjust. Identities = 106/231 (45%), Positives = 159/231 (68%), Gaps = 3/231 (1%) Query: 3 TILIADDELEIVELLQLYLEKE-YNILQAQNGNEALKLMQSHTVDLAILDIMMPGMDGLQ 61 T+L+ DDE EI +L+ +YL E +N+++A+NG EAL++++ V L +LDIMMP MDG+ Sbjct: 5 TVLVVDDEKEIRDLIGIYLNNEGFNVIKAENGVEALEILKDTEVQLVLLDIMMPKMDGIT 64 Query: 62 LLKRIRENDHFPVLFLSAKSQYHDKILGLELGADDYISKPFNPLEIVARVGSMLRRVHEF 121 +IRE+ + P++ LSAK + DKILGL GADDYISKPFNPLE++ARV S +RR + Sbjct: 65 TCMKIREDKNTPIIMLSAKGEDMDKILGLTTGADDYISKPFNPLELIARVKSQIRRYTKL 124 Query: 122 DAPAVQEKKKEQIVLGRLLLDRSSCQVEVDGEPVALTSTEYKILELLMEQPGRVFTRKKI 181 + + E I +G + ++ + +V++ V+LT E+ IL LL G VF+ +KI Sbjct: 125 N--STYESNSANIEVGEITINTDTHEVKIGDRTVSLTKREFDILVLLSRNKGVVFSTEKI 182 Query: 182 YEAVWEDFYVYEDNSIMVHISNIRDKIERDSKKPEYLKTIRGLGYKIEAPV 232 YE+VW + + N++MVHI IR+KIE++ +KPEY+KT+ G+GYKIE + Sbjct: 183 YESVWHEEFYDCHNTVMVHIRKIREKIEKNPRKPEYIKTVWGVGYKIEKNI 233 >BH1153 [TK] COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Length = 232 Score = 209 bits (531), Expect = 4e-54, Method: Compositional matrix adjust. Identities = 108/230 (46%), Positives = 155/230 (67%), Gaps = 5/230 (2%) Query: 2 YTILIADDELEIVELLQLYLEKE-YNILQAQNGNEALKLMQSHTVDLAILDIMMPGMDGL 60 Y +L+ DD+ EI E + +YL+ E N+ QA++G EAL+ + + L +LD+MMP +DG+ Sbjct: 5 YNVLVVDDDKEIREGITIYLKNEGMNVFQAKDGIEALERLNEEDIHLMLLDVMMPRLDGI 64 Query: 61 QLLKRIRENDHFPVLFLSAKSQYHDKILGLELGADDYISKPFNPLEIVARVGSMLRRVHE 120 Q +IRE + P++FLSAKS+ DK+LGL++G DDY++KPFNPLE++ARV S LRR Sbjct: 65 QTTLKIREARNIPIIFLSAKSEEADKVLGLQVGGDDYVTKPFNPLELIARVKSQLRRYVN 124 Query: 121 FDAPAVQEKKKEQIVLGRLLLDRSSCQVEVDGEPVALTSTEYKILELLMEQPGRVFTRKK 180 E+KK+ I L + LD + +V+ GEPV LT EY+I+ELLM GRVF+ + Sbjct: 125 L---GTYEQKKQLINLNGITLDLDAKEVKAYGEPVKLTPIEYRIIELLMTNAGRVFSIAE 181 Query: 181 IYEAVW-EDFYVYEDNSIMVHISNIRDKIERDSKKPEYLKTIRGLGYKIE 229 IYE VW E + +N++ VHI IR+KIE D P +LK + G+GYK+E Sbjct: 182 IYERVWNEPSFQSSENTVAVHIRKIREKIEIDPSNPRHLKVVWGIGYKME 231 >lin2516 [TK] COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Length = 231 Score = 192 bits (488), Expect = 4e-49, Method: Compositional matrix adjust. Identities = 104/231 (45%), Positives = 155/231 (67%), Gaps = 8/231 (3%) Query: 3 TILIADDELEIVELLQLYLEKE-YNILQAQNGNEALKLMQSHTVDLAILDIMMPGMDGLQ 61 +ILIADD+ EIV+L++LYL+ E Y I QA +G E +L+Q L ILDIMMP M+GL+ Sbjct: 4 SILIADDDKEIVDLVKLYLQNEGYTIYQAYDGAEVWRLVQEKQPTLVILDIMMPEMNGLE 63 Query: 62 LLKRIRENDHF-PVLFLSAKSQYHDKILGLELGADDYISKPFNPLEIVARVGSMLRRVHE 120 + + +R N P+L LSAK++ +DKI+GL GADDY+ KPFNPLE+ RV ++LRR+ + Sbjct: 64 VCRLMRNNGILTPILMLSAKAEDNDKIMGLLTGADDYMVKPFNPLELSVRVKAILRRMQQ 123 Query: 121 FDA--PAVQEKKKEQIVLGRLLLDRSSCQVEVDGEPVALTSTEYKILELLMEQPGRVFTR 178 P Q+K +++G +++DR V V + + LT++E+ IL LL +PGRVF+ Sbjct: 124 MSQAEPVSQDK----VIIGPIVVDRGLHVVTVGEKELHLTTSEFDILFLLASEPGRVFSS 179 Query: 179 KKIYEAVWEDFYVYEDNSIMVHISNIRDKIERDSKKPEYLKTIRGLGYKIE 229 + I+E +W++ + ++MVHISN+RDK+ +KTI G+GYKIE Sbjct: 180 EYIFEKIWQEKALGASKTVMVHISNLRDKLRDAMGGENVIKTIWGVGYKIE 230 >BS_phoP [TK] COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Length = 223 Score = 187 bits (476), Expect = 9e-48, Method: Compositional matrix adjust. Identities = 0/233 (0%), Positives = 0/233 (0%), Gaps = 6/233 (2%) Query: 4 ILIADDELEIVELLQLYLEKE-YNILQAQNGNEALKLMQSHTVDLAILDIMMPGMDGLQL 62 ++ + L +Q+ + + + + + L + L Sbjct: 5 VVEDNALLRHHLKVQIQDAGHQVDDAEDAKEADYYLNEHIPDIAIVDLGLPDEDGLSLIR 64 Query: 63 LKRIREND-HFPVLFLSAKSQYHDKILGLELGADDYISKPFNPLEIVARVGSMLRRVHEF 121 R + VL Q ++L + + Sbjct: 65 RWRSNDVSLPILVLTARESWQDKVEVLSAGADDYVTKPFHIEEVMARMQALMRRNS-GLA 123 Query: 122 DAPAVQEKKKE---QIVLGRLLLDRSSCQVEVDGEPVALTSTEYKILELLMEQPGRVFTR 178 + + L E + + + + + Sbjct: 124 SQVISLPPFQVDLSRRELSINDEVIKLTAFEYTIMETLIRNNGKVVSKDSLMLQLYPDAE 183 Query: 179 KKIYEAVWEDFYVYEDNSIMVHISNIRDKIERDSKKPEYLKTIRGLGYKIEAP 231 Sbjct: 184 236 >lin2644 [TK] COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Length = 236 Score = 185 bits (470), Expect = 5e-47, Method: Compositional matrix adjust. Identities = 100/234 (42%), Positives = 157/234 (67%), Gaps = 6/234 (2%) Query: 1 MYTILIADDELEIVELLQLYLEKE-YNILQAQNGNEALKLMQSHTVDLAILDIMMPGMDG 59 M IL+ DDE IV LLQ +EK ++++ A++G +L S DL +LD+M+P MDG Sbjct: 1 MVKILVVDDEASIVTLLQFNIEKAGFDVVTAEDGRTGYELALSEKPDLIVLDLMLPEMDG 60 Query: 60 LQLLKRIREND-HFPVLFLSAKSQYHDKILGLELGADDYISKPFNPLEIVARVGSMLRRV 118 +++ K++R++ P+L L+AK + DKI+GLELGADDY++KPF+P E+VAR+ ++LRR Sbjct: 61 IEVTKKLRQDKVGVPILMLTAKDEELDKIIGLELGADDYMTKPFSPREVVARIKAILRRT 120 Query: 119 HEFDAPAVQEKKKEQ---IVLGRLLLDRSSCQVEVDGEPVALTSTEYKILELLMEQPGRV 175 E A +EK ++ I++G L + S +V + + + LT E+++L L G+V Sbjct: 121 -EGKAEVTEEKTEDTEATILIGDLKILPDSYEVYLQDDLLDLTPKEFELLLFLANHRGKV 179 Query: 176 FTRKKIYEAVWEDFYVYEDNSIMVHISNIRDKIERDSKKPEYLKTIRGLGYKIE 229 F+R ++ + VW YV E + VH+S++RDKIE D+K+P+Y+KTIRG GYK+E Sbjct: 180 FSRDQLLDTVWNYDYVGETRIVDVHVSHLRDKIELDTKQPKYIKTIRGFGYKME 233 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.319 0.139 0.387 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 17,550,999 Number of extensions: 679313 Number of successful extensions: 7302 Number of sequences better than 1.0e-05: 521 Number of HSP's gapped: 6786 Number of HSP's successfully gapped: 522 Length of query: 234 Length of database: 38,378,431 Length adjustment: 103 Effective length of query: 131 Effective length of database: 26,499,029 Effective search space: 3471372799 Effective search space used: 3471372799 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 114 (48.5 bits)