BLASTP 2.2.18 [Mar-02-2008]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment: Altschul, Stephen F., 
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= 0521.0004.p
         (368 letters)

Database: COG 
           115,334 sequences; 38,378,431 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

BH2921 [R] COG0628 Predicted permease                                 192   5e-49
BS_yueF [R] COG0628 Predicted permease                                184   3e-46
lin0908 [R] COG0628 Predicted permease                                164   2e-40
lin0593 [R] COG0628 Predicted permease                                152   8e-37
SP1505 [R] COG0628 Predicted permease                                 147   2e-35

>BH2921 [R] COG0628 Predicted permease
          Length = 361

 Score =  192 bits (489), Expect = 5e-49,   Method: Compositional matrix adjust.
 Identities = 116/357 (32%), Positives = 203/357 (56%), Gaps = 9/357 (2%)

Query: 9   RICIAVLLVLGIIYLGTQVKFIFTPVLSLFRVVIVPLMLAVFFFYLLRPLINWLESRKLN 68
           R    ++LVL IIYLG+ V +IF P++   + +  P+++A   +YL RP++  L S+K+N
Sbjct: 8   RFGYGIVLVLLIIYLGSLVDWIFRPIVVFVQTLFAPVIIAGILYYLFRPIVGLL-SKKMN 66

Query: 69  RTXXXXXXXXXXXXXXXXFSVGVWPSLKSQLVNLGNNMPNVFNALGEQLTKLEDSKLLS- 127
           R                 FS+ V P L+ Q  +L NN+P + N + +    L+ ++L + 
Sbjct: 67  RGLSILILFLMIIGAFTAFSLIVGPELQRQFQSLYNNLPTLINQVRDTFIALQSNELFNR 126

Query: 128 -----SLIPADMNPAGQLMNYLNKGFSLLSNSMSELFSFVSNFAVVLFTFPILLFYMLKE 182
                +  P +M    + +N LN     +  +++     ++NF ++L   P +LFY+LKE
Sbjct: 127 FQESETFQPEEM--ISRFVNSLNDIIGTIGANITGFIGALANFFIILVLVPFILFYLLKE 184

Query: 183 GGKFGVKVVSFFPKRFHKEGEGVVADIDEAMSNFIVGRVLVNLALGVLMYLGFLLIGLPY 242
           G K  V+++  F K+   EG  ++AD+D+ +S++I G+++V+  +G+L Y+ +L+IGL Y
Sbjct: 185 GEKLPVQLLKLFNKKQQHEGRLILADMDKMLSSYIQGQIIVSFCVGILCYIAYLIIGLDY 244

Query: 243 ALLLTVVAVLMNFIPFIGAILSTVPIFIIGLMESPSTAIWSIVVVLVAQQIQDNLVAPYI 302
           AL+L +VA+  N IPF+G  + T P  I+  ++SP TA+  ++VV+V QQI+ NL++P +
Sbjct: 245 ALILALVAMFTNVIPFVGPWIGTFPAVIVAFIDSPLTALIVVIVVVVIQQIESNLISPQV 304

Query: 303 FGKSLDIHPLTTIILVLAXXXXXXXXXXXXXXPVYMMLKIITVKLHQLYMRQRWPEE 359
            GK L IHP+T I ++L               P Y + K+I    ++L+  ++ P E
Sbjct: 305 MGKKLAIHPITIIFILLVAGRFAGVVGMLLAVPTYAVGKVIVTHSYRLWKLRKQPVE 361


>BS_yueF [R] COG0628 Predicted permease
          Length = 369

 Score =  184 bits (466), Expect = 3e-46,   Method: Compositional matrix adjust.
 Identities = 105/358 (29%), Positives = 189/358 (52%), Gaps = 8/358 (2%)

Query: 11  CIAVLLVLGIIYLGTQVKFIFTPVLSLFRVVIVPLMLAVFFFYLLRPLINWLESRKLNRT 70
            + +L VL II++ T+V F+F P +     +  P+++A   +++  P++  LE +K+ RT
Sbjct: 10  TLQILFVLLIIFVATKVSFVFQPFIVFISTLFFPMLIAGILYFIFNPVVRLLE-KKIPRT 68

Query: 71  XXXXXXXXXXXXXXXXFSVGVWPSLKSQLVNLGNNMPNVFNALGEQLTKLEDSKLLSSLI 130
                            S  V P + +Q+  L NN+P+    +      L  S+  + ++
Sbjct: 69  LSILLIYLLFIGLLAFISASVGPIITAQVTGLFNNLPDYIKQIQALTKDLSHSQWFTWMM 128

Query: 131 PADMNPAGQ----LMNYLNKGFSLLSNSMSELFSFVSNFAVVLFTFPILLFYMLKEGGKF 186
             D     +    L ++L      +++S+S +F  V+N  +V+ T P +LFYMLK+G +F
Sbjct: 129 NQDYVSISKIEQSLTSFLQNLPQNITSSLSAVFGVVTNITLVIITVPFILFYMLKDGHRF 188

Query: 187 GVKVVSFFPKRFHKEGEGVVADIDEAMSNFIVGRVLVNLALGVLMYLGFLLIGLPYALLL 246
               V   P  +  EG  +  D+ + ++ +  G++L+ L +G   ++G+L+ GLPYAL+L
Sbjct: 189 PHLAVKILPASYRTEGLKIFKDLSDTLAAYFQGQLLICLFVGTACFIGYLIAGLPYALIL 248

Query: 247 TVVAVLMNFIPFIGAILSTVPIFIIGLMESPSTAIWSIVVVLVAQQIQDNLVAPYIFGKS 306
            +V  + N IP++G  L   P  I+G M+SP+ A+++I+VV++ QQ+  NL++P + GK 
Sbjct: 249 GIVMAITNIIPYVGPFLGAAPAVIVGFMDSPAKALFAIIVVVIVQQLDGNLLSPLVIGKR 308

Query: 307 LDIHPLTTIILVLAXXXXXXXXXXXXXXPVYMMLKII---TVKLHQLYMRQRWPEEPQ 361
           L+ HPLT I+L++               PVY ++K      V+L +L  R R  E  +
Sbjct: 309 LNTHPLTIILLLIGAGSFGGILGMILAVPVYAVVKAFFLNIVRLIKLRQRSRLEENAK 366


>lin0908 [R] COG0628 Predicted permease
          Length = 378

 Score =  164 bits (415), Expect = 2e-40,   Method: Compositional matrix adjust.
 Identities = 112/360 (31%), Positives = 189/360 (52%), Gaps = 12/360 (3%)

Query: 11  CIAVLLVLGIIYLGTQVKFIFTPVLSLFRVVIVPLMLAVFFFYLLRPLINWLESRKLNRT 70
            I +L V+ ++++  Q+K+IF+P+  +   + +P+++A F FYL  PL+ +LE RK+ R 
Sbjct: 15  TIEILAVVAVLFILLQMKYIFSPIGIIVSTLFMPILVAGFLFYLFNPLVLFLEKRKVPRL 74

Query: 71  XXXXXXXXXXXXXXXXFSVGVWPSLKSQLVNLGNNMPNVFNALGEQLTKLEDSKLLSSLI 130
                             + + P+L  Q+  L   +P  +    + L  L ++  L  + 
Sbjct: 75  LSVILIFIAFIALVVLAVMQLGPTLADQVAELAKAIPGYWQDFEKWLQSLSNNSALKDI- 133

Query: 131 PADMNPAGQLMN-YLNKGFSLL----SNSMSELFSFVSNFAVVLFTFPILLFYMLKEGGK 185
             DM      +N  L K  S++    ++S   + SFVS F ++L T P ++FYM K+G K
Sbjct: 134 --DMKQELSKLNISLPKIMSVVVDGVASSFGAIISFVSGFVMILVTVPFIVFYMFKDGHK 191

Query: 186 FGVKVVSFFPKRFHKEGEGVVADIDEAMSNFIVGRVLVNLALGVLMYLGFLLIGLPYALL 245
           F      FFP     E + ++ ++++ +S +I  + +  + +G+  ++G+L+IG PYALL
Sbjct: 192 FVESSGKFFPAGIRTEAKQIIKEMNKTISTYISSQAIDCMFVGLFTFIGYLIIGQPYALL 251

Query: 246 LTVVAVLMNFIPFIGAILSTVPIFIIGLMESPSTAIWSIVVVLVAQQIQDNLVAPYIFGK 305
              +A   N IP++G  L   P  I+ L  SP  A+  IVVV + QQI  NL++PYI GK
Sbjct: 252 FGFIAGATNIIPYLGPFLGAAPAVIVALFTSPVQALLVIVVVTIVQQIDSNLLSPYIMGK 311

Query: 306 SLDIHPLTTIILVLAXXXXXXXXXXXXXXPVYMMLKIITVKLHQLYMRQRWPEEPQLSAD 365
           SL IHPLT II+++               P+Y ++K I V +++L   +R     QL+ D
Sbjct: 312 SLSIHPLTIIIILIVAGNLAGIFGMILGVPLYAVVKTIIVNVNRLIKLRRG----QLAID 367


>lin0593 [R] COG0628 Predicted permease
          Length = 389

 Score =  152 bits (384), Expect = 8e-37,   Method: Compositional matrix adjust.
 Identities = 98/363 (26%), Positives = 189/363 (52%), Gaps = 6/363 (1%)

Query: 5   NLFIRICIAVLLVLGIIYLGTQVKFIFTPVLSLFRVVIVPLMLAVFFFYLLRPLINWLES 64
           N F+   +  LLV   IY+ T++ FIF P++ + + V  P++LA   +YL  P+I+WLE 
Sbjct: 15  NKFVLGLLIFLLVALDIYVLTKIAFIFDPLMVILKTVAAPIILAGISYYLFNPIIDWLEK 74

Query: 65  RKLNRTXXXXXXXXXXXXXXXXFSVGVWPSLKSQLVNLGNNMPNVFNALGEQLTKLEDSK 124
           +K  R                     V P++K Q+V+L  + P  ++ + ++  +   S 
Sbjct: 75  KKWKRGWAIALLYLVIIGLIILLFSFVIPAVKDQIVSLFKSFPGYWDQITQKFDEFSRSS 134

Query: 125 LLSSLIPADMNPAGQLMNYLN-KGFSLLSNSMSELFSFVSNFAVVLF---TFPILLFYML 180
           L   +          +M  L+ KG S+++++++ + S V     V+    T P++LFY+L
Sbjct: 135 LFDQIKDKLSTNMSDIMKTLSTKGTSVINSAITSIGSIVGTVTEVVLAIVTTPLVLFYLL 194

Query: 181 KEGGKFGVKVVSFFPKRFHKEGEGVVADIDEAMSNFIVGRVLVNLALGVLMYLGFLLIGL 240
           K+G K    ++   P         V+ + +  +S++I G+++V+L +G+L+++G+L+IGL
Sbjct: 195 KDGKKLPDFLLKMLPVNGRAHTRQVLGEANHQISSYIRGQIIVSLCIGILLFIGYLIIGL 254

Query: 241 PYALLLTVVAVLMNFIPFIGAILSTVPIFIIGLMESPSTAIWSIVVVLVAQQIQDNLVAP 300
           PYAL L ++A   + +P++G  ++  P  II ++ SP   I  I+V  V Q ++   ++P
Sbjct: 255 PYALTLAIIAACTSIVPYLGPAIAITPAIIIAIVTSPWLLIKLIIVWCVVQLLEGKFISP 314

Query: 301 YIFGKSLDIHPLTTIILVLAXXXXXXXXXXXXXXPVYMMLKIITVKLHQLYMRQR--WPE 358
            + GK+L +HP+T + ++L               P Y +LK++   +   + R    + E
Sbjct: 315 QVMGKTLKVHPITILFVILVAGNLFGILGVIFAVPGYAVLKVVVTHVFIWFKRVSGLYGE 374

Query: 359 EPQ 361
           +P+
Sbjct: 375 QPE 377


>SP1505 [R] COG0628 Predicted permease
          Length = 388

 Score =  147 bits (372), Expect = 2e-35,   Method: Compositional matrix adjust.
 Identities = 89/336 (26%), Positives = 173/336 (51%), Gaps = 14/336 (4%)

Query: 25  TQVKFIFTPVLSLFRVVIVPLMLAVFFFYLLRPLINWLESRKLNRTXXXXXXXXXXXXXX 84
           +++ F+F+PVL    VV++P++L+   +YLL P+++W+E  K+NR               
Sbjct: 40  SKISFLFSPVLDFLAVVMLPVILSGLLYYLLNPIVDWMEKHKVNRVIAITIVFVIIALFI 99

Query: 85  XXFSVGVWPSLKSQLVNLGNNMPNVFNALGEQLTKLEDSKLLSSLIPADMNPAGQ--LMN 142
                   P+L+ Q++    N+P       E + ++ +  L++  +P D  P  +  L N
Sbjct: 100 IWGLAVAIPNLQRQVLTFARNVPVYL----EDIDRIVNG-LVAQHLPDDFRPQLEQVLTN 154

Query: 143 YLNKGFSLLSNSMSELFSFVSNFA-------VVLFTFPILLFYMLKEGGKFGVKVVSFFP 195
           + ++   L S   S+  ++VS F        V L   P +LFY+L++G      +  F P
Sbjct: 155 FSSQATVLASKVSSQAVNWVSAFISGASQVIVALIIVPFMLFYLLRDGKGLRNYLTQFIP 214

Query: 196 KRFHKEGEGVVADIDEAMSNFIVGRVLVNLALGVLMYLGFLLIGLPYALLLTVVAVLMNF 255
           ++  +    V++D+++ +SN++ G+V V + + V+  + F +IGL YA+ L V A ++N 
Sbjct: 215 RKLKEPVGQVLSDVNQQLSNYVRGQVTVAIIVAVMFIIFFKIIGLRYAVTLGVTAGILNL 274

Query: 256 IPFIGAILSTVPIFIIGLMESPSTAIWSIVVVLVAQQIQDNLVAPYIFGKSLDIHPLTTI 315
           +P++G+ L+ +P  ++GL+  P   +  ++V +V Q I+   V+P I G  L+IHP+  +
Sbjct: 275 VPYLGSFLAMLPALVLGLIAGPVMLLKVVIVFIVEQTIEGRFVSPLILGSQLNIHPINVL 334

Query: 316 ILVLAXXXXXXXXXXXXXXPVYMMLKIITVKLHQLY 351
            ++L               PVY   K++   + + Y
Sbjct: 335 FVLLTSGSMFGIWGVLLGIPVYASAKVVISAIFEWY 370


  Database: COG
    Posted date:  Aug 3, 2010  9:58 AM
  Number of letters in database: 38,378,431
  Number of sequences in database:  115,334
  
Lambda     K      H
   0.330    0.145    0.425 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 115334
Number of Hits to DB: 23,144,960
Number of extensions: 866690
Number of successful extensions: 3212
Number of sequences better than 1.0e-05: 86
Number of HSP's gapped: 3115
Number of HSP's successfully gapped: 86
Length of query: 368
Length of database: 38,378,431
Length adjustment: 108
Effective length of query: 260
Effective length of database: 25,922,359
Effective search space: 6739813340
Effective search space used: 6739813340
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.8 bits)
S2: 116 (49.3 bits)