BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0520.0046.p (261 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value CAC0023 [K] COG0583 Transcriptional regulator 114 1e-25 cynR [K] COG0583 Transcriptional regulator 100 3e-21 BH2102 [K] COG0583 Transcriptional regulator 96 4e-20 lin1846 [K] COG0583 Transcriptional regulator 92 8e-19 XF1532 [K] COG0583 Transcriptional regulator 90 3e-18 >CAC0023 [K] COG0583 Transcriptional regulator Length = 299 Score = 114 bits (286), Expect = 1e-25, Method: Compositional matrix adjust. Identities = 75/243 (30%), Positives = 124/243 (51%), Gaps = 4/243 (1%) Query: 1 MEIRLIKTFQTIVKLGNFQRAAAALQYSQPTITSQIKKLEEELGVKLFER-GKTITLTTA 59 M+ + + TF + K +F AA +L Y+Q T+T+QIK LEEEL +KLFER GK +TLT Sbjct: 1 MDFKQLNTFIAVSKYQSFTEAAHSLNYAQSTVTTQIKILEEELQIKLFERIGKKVTLTYE 60 Query: 60 GRLLHERADSLLREYDDLNVALYDFIQGDAGLVRIGASEPSASNRVPDILASFTRKKPKA 119 G+ L A +++ +++ + D + +G + IGA+E R+P+IL + R P Sbjct: 61 GKKLLPYAKQMIKLSNEIKKVVLD-DEKPSGTLTIGAAESLCVIRLPEILKEYRRLYPDV 119 Query: 120 QTKVTIGTTRELVNMLLEDQIDLALC-NQXXXXXXXXXXXXXXXTFKLIVPADHPLAARE 178 + + G+ + + L ++ ID+A L+ DHPL +E Sbjct: 120 EVSLKFGSCADFRHFLKDNIIDVAFSLGTKIDSNEFISEVEFDEPMILLAYPDHPLVKKE 179 Query: 179 HIRLKDLQDEVFLFTPGSCAFRIRIEEMITKHIGKLRQSSIEVAGITAIKYYVQSRLGIA 238 I +D+ +E + T C++R E ++ + K + +E + AIK + SRLGI Sbjct: 180 KIYPEDIVEEPLVLTEMGCSYRAAFENILRSYNIKPKL-VLETGSVQAIKQFTMSRLGIT 238 Query: 239 LAP 241 L P Sbjct: 239 LLP 241 >cynR [K] COG0583 Transcriptional regulator Length = 299 Score = 100 bits (248), Expect = 3e-21, Method: Compositional matrix adjust. Identities = 69/228 (30%), Positives = 108/228 (47%), Gaps = 2/228 (0%) Query: 1 MEIRLIKTFQTIVKLGNFQRAAAALQYSQPTITSQIKKLEEELGVKLFER-GKTITLTTA 59 M R I F + + G+F RAA+AL SQP ++ QI++LEE LGV LF+R G+TI LT A Sbjct: 1 MLSRHINYFLAVAEHGSFTRAASALHVSQPALSQQIRQLEESLGVPLFDRSGRTIRLTDA 60 Query: 60 GRLLHERADSLLREYDDLNVALYDFIQGDAGLVRIGASEPSASNRVPDILASFTRKKPKA 119 G + + A L+E A++D G +RI + S + ++A F + P Sbjct: 61 GEVWRQYASRALQELGAGKRAIHDVADLTRGSLRIAVTPTFTSYFIGPLMADFYARYPSI 120 Query: 120 QTKVTIGTTRELVNMLLEDQIDLALCNQXXXXXXXXXXXXXXXTFKLIVPADHPLAAREH 179 ++ + ++ +ML D++D+ + + L+V HPLA E Sbjct: 121 TLQLQEMSQEKIEDMLCRDELDVGIAFAPVHSPELEAIPLLTESLALVVAQHHPLAVHEQ 180 Query: 180 IRLKDLQDEVFLFTPGSCAFRIRIEEMITKHIGKLRQSSIEVAGITAI 227 + L L DE + A R +I+ K G Q IE I+A+ Sbjct: 181 VALSRLHDEKLVLLSAEFATREQIDHYCEK-AGLHPQVVIEANSISAV 227 >BH2102 [K] COG0583 Transcriptional regulator Length = 301 Score = 96.3 bits (238), Expect = 4e-20, Method: Compositional matrix adjust. Identities = 66/243 (27%), Positives = 114/243 (46%), Gaps = 3/243 (1%) Query: 1 MEIRLIKTFQTIVKLGNFQRAAAALQYSQPTITSQIKKLEEELGVKLFER-GKTITLTTA 59 ME R + F + K + AAAAL +Q ++ QI LE ELGV LF R G+ + LT Sbjct: 1 MEFRQLTYFMEVAKREHVTEAAAALHVAQSAVSRQIFNLENELGVDLFIRDGRRVKLTPI 60 Query: 60 GRLLHERADSLLREYDDLNVALYDFIQGDAGLVRIGASEPSASNRVPDILASFTRKKPKA 119 G++ ER + DD + +++ + G +R+ A+ +P ++ +F ++ P+A Sbjct: 61 GKMFLERITHAMNVIDDAKREVQEYLDPEKGTIRVAFPISLAAYTLPTVIYAFRKRYPEA 120 Query: 120 QTKVTIGTTRELVNMLLEDQIDLALCNQXXXXXXXXX-XXXXXXTFKLIVPADHPLAARE 178 + ++ EL+N +++ ++AL ++P HPLA Sbjct: 121 KFQLKQALYHELINGVIKGDYNMALIGPVPMDEKKIARKILFTEQVVALLPLHHPLAENN 180 Query: 179 HIRLKDLQDEVFLFTPGSCAFRIRIEEMITKHIGKLRQSSIEVAGITAIKYYVQSRLGIA 238 I L+DL+D+ F+ P FR + + +G + E I A+K V + LG+ Sbjct: 181 AIHLRDLKDDPFVLLPEGFVFRDIVINACSD-LGFYPNIAFEGDDIDALKGLVSAGLGVT 239 Query: 239 LAP 241 L P Sbjct: 240 LMP 242 >lin1846 [K] COG0583 Transcriptional regulator Length = 295 Score = 92.0 bits (227), Expect = 8e-19, Method: Compositional matrix adjust. Identities = 67/246 (27%), Positives = 114/246 (46%), Gaps = 9/246 (3%) Query: 1 MEIRLIKTFQTIVKLGNFQRAAAALQYSQPTITSQIKKLEEELGVKLFER-GKTITLTTA 59 ME+R +K F + ++ + +A+ L +Q ++ QI KLEEELGV LF+R G+ + LT+ Sbjct: 1 MELRQLKYFMEVARVEHMTKASENLHVAQSAVSRQITKLEEELGVPLFDRVGRNMQLTSV 60 Query: 60 GRLLHERADSLLREYDDLNVALYDFIQGDAGLVRIGASEPSASNRVPDILASFTRKKPKA 119 G+ +A L E + ++ G VR+G ++ +P ++++F K P+ Sbjct: 61 GQDFLSQATIALNELQKAEALVTEYTDPTKGTVRVGLPNSLSTKVLPSVISTFREKYPEI 120 Query: 120 QTKVTIGTTRELVNMLLEDQIDLALCNQX-XXXXXXXXXXXXXXTFKLIVPADHPLAARE 178 + GT EL ML+ +D+ + KLIVP H LA Sbjct: 121 TYQFMEGTNEELTEMLVNGVLDMTFLSPVPESSEQIEALRFFDEKLKLIVPTSHHLAENF 180 Query: 179 HIRLKDLQDEVFLFTPGSCAFRIRIEEMITKHIGKLR---QSSIEVAGITAIKYYVQSRL 235 + LK+L E F+ P + +++TK K Q + + I+ V + L Sbjct: 181 TVSLKELSSEKFVLYPED----FDLYKIVTKAANKKGFEPQIAFQSRDFYTIQGLVGAGL 236 Query: 236 GIALAP 241 GI++ P Sbjct: 237 GISILP 242 >XF1532 [K] COG0583 Transcriptional regulator Length = 325 Score = 90.1 bits (222), Expect = 3e-18, Method: Compositional matrix adjust. Identities = 74/251 (29%), Positives = 118/251 (47%), Gaps = 6/251 (2%) Query: 1 MEIRLIKTFQTIVKLGNFQRAAAALQYSQPTITSQIKKLEEELGVKLFERG-KTITLTTA 59 M +R +K + +F RAA A SQPT+++QIKKLE ELGV L ER + + +T A Sbjct: 15 MNLRDLKYLIALADYKHFGRAATACFVSQPTLSTQIKKLEGELGVSLVERAPRKVMMTPA 74 Query: 60 GRLLHERADSLLREYDDLNVALYDFIQGDAGLVRIGASEPSASNRVPDILASFTRKKPKA 119 GR RA S++ E +++ A +AG VR+G +P ++ S + P+ Sbjct: 75 GREAAIRARSIVAEVEEMKEAARRSRDPEAGAVRLGIFPTLGPYLLPHVVPSIRYRFPQL 134 Query: 120 QTKVTIGTTRELVNMLLEDQIDLALCNQXXXXXXXXXXXXXXXTFKLIVPADHPLAAREH 179 + + + EL+ L E ++D AL F L VP HPLA R Sbjct: 135 ELLLVEEKSDELLAQLREGKLDAALLALPLHDEQLHTEFLFEEPFVLAVPEGHPLATRRE 194 Query: 180 IRLKDLQDE-VFLFTPGSCAFRIRIEEMITKHI-GKLRQSSIEVAGITAIKYYVQSRLGI 237 + +++L DE + L G C +R + + H+ G +S + + ++ V + +GI Sbjct: 195 MTMEELADERLLLLQDGHC---LREQALDVCHMTGASEKSEFQATSLETLRQMVVANVGI 251 Query: 238 ALAPXXXXPSP 248 L P P Sbjct: 252 TLLPLLSVKPP 262 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.322 0.137 0.378 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 15,237,614 Number of extensions: 480846 Number of successful extensions: 4012 Number of sequences better than 1.0e-05: 1486 Number of HSP's gapped: 3971 Number of HSP's successfully gapped: 1486 Length of query: 261 Length of database: 38,378,431 Length adjustment: 104 Effective length of query: 157 Effective length of database: 26,383,695 Effective search space: 4142240115 Effective search space used: 4142240115 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.9 bits) S2: 115 (48.9 bits)