BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0520.0036.p (249 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value mll7342 [S] COG2343 Uncharacterized protein conserved in bacteria 213 2e-55 mll2277 [S] COG2343 Uncharacterized protein conserved in bacteria 201 1e-51 Rv1056 [S] COG2343 Uncharacterized protein conserved in bacteria 153 3e-37 MT1085 [S] COG2343 Uncharacterized protein conserved in bacteria 153 3e-37 alr4241 [S] COG2343 Uncharacterized protein conserved in bacteria 80 2e-15 >mll7342 [S] COG2343 Uncharacterized protein conserved in bacteria Length = 247 Score = 213 bits (543), Expect = 2e-55, Method: Compositional matrix adjust. Identities = 102/230 (44%), Positives = 140/230 (60%) Query: 2 LXXXXGGDYIADSKEVMVVTETGRLPVYYFPLKDVNAALFQPSEKLATHPQKGIQTFWDI 61 L G +AD+ + +V+ E+ LPVYYFP+ DV PS P KG+ T + + Sbjct: 7 LRVQVGSMIVADTTKALVLYESDHLPVYYFPMSDVREEFLLPSRTTTESPFKGVATHYSL 66 Query: 62 TSGGRTARNAVWTYSGPQPEAHFLHGYVSFSWSKMDGWFEEEEEVFVHARDPYTRVDAIP 121 +G +A W Y P + L GY+SF W KM W+EE+EE+FVHARDP+ RVD +P Sbjct: 67 NTGITLVEDAAWRYLDPVKGSPDLSGYMSFYWPKMTHWYEEDEEIFVHARDPFRRVDCLP 126 Query: 122 ASRHVQLEVNGIIVADSRRPVILYETGLTPRYYLPAEDVRLDLLQENPNSTRCPYKGIAT 181 +SR VQ+ ++G VADSRR V L+ETG R+YLP D RLD+ + +RCPYKGI+ Sbjct: 127 SSRRVQVILDGEQVADSRRGVFLFETGHPVRHYLPISDTRLDMFAPSRYISRCPYKGISN 186 Query: 182 YWTAAVNGREYEDLVWSYKEPLPEVHEIAGLLCFYHEAADALYVDGIKWS 231 Y+ + +E+LVW Y EP+ E I GL+CF+HE D + VDG+ S Sbjct: 187 YYHVTTPQKRHENLVWYYPEPVHEAERIKGLVCFHHELVDKILVDGVDIS 236 Score = 71.2 bits (173), Expect = 2e-12, Method: Compositional matrix adjust. Identities = 31/97 (31%), Positives = 57/97 (58%) Query: 120 IPASRHVQLEVNGIIVADSRRPVILYETGLTPRYYLPAEDVRLDLLQENPNSTRCPYKGI 179 +P + ++++V +IVAD+ + ++LYE+ P YY P DVR + L + +T P+KG+ Sbjct: 1 MPMQKRLRVQVGSMIVADTTKALVLYESDHLPVYYFPMSDVREEFLLPSRTTTESPFKGV 60 Query: 180 ATYWTAAVNGREYEDLVWSYKEPLPEVHEIAGLLCFY 216 AT+++ ED W Y +P+ +++G + FY Sbjct: 61 ATHYSLNTGITLVEDAAWRYLDPVKGSPDLSGYMSFY 97 >mll2277 [S] COG2343 Uncharacterized protein conserved in bacteria Length = 257 Score = 201 bits (510), Expect = 1e-51, Method: Compositional matrix adjust. Identities = 106/224 (47%), Positives = 153/224 (68%), Gaps = 4/224 (1%) Query: 7 GGDYIADSKEVMVVTETGRLPVYYFPLKDVNAALFQPSEKLATHPQKGIQTFWDITSGGR 66 GG IADS+ V+V+ LP+Y+FP V+A++ +PS H G +WDI SG R Sbjct: 32 GGRTIADSRNVLVLRSNHFLPIYFFPPSSVDASVLKPSLHREPHAVGGETAYWDIDSGDR 91 Query: 67 TARNAVWTYSGPQPEAHF--LHGYVSFSWSKMDGWFEEEEEVFVHARDPYTRVDAIPASR 124 A NA W+++ P P+ + L G ++F+W +D WFEEEEEVFVHARDPY R+D + +S Sbjct: 92 RAANAAWSFTAP-PDENLSPLAGRIAFTWKAVDQWFEEEEEVFVHARDPYARIDVLHSSS 150 Query: 125 HVQLEVNGIIVADSRRPVILYETGLTPRYYLPAEDVRLDLLQENPNSTRCPYKGIATYWT 184 HVQ+ +G I+ADS RPV+L+ET L R+YL EDVRL+ L + ++TRCPYKGIA+YW+ Sbjct: 151 HVQVWFDGDIIADSHRPVLLFETHLPTRFYLRPEDVRLERLTASSSTTRCPYKGIASYWS 210 Query: 185 AAV-NGREYEDLVWSYKEPLPEVHEIAGLLCFYHEAADALYVDG 227 + +G D+ WSY++P+ E+ +I GL+ FY +A D +++DG Sbjct: 211 GLLKDGSVRPDIAWSYRDPIDEMPKIKGLIAFYPQAVDRIHLDG 254 >Rv1056 [S] COG2343 Uncharacterized protein conserved in bacteria Length = 254 Score = 153 bits (386), Expect = 3e-37, Method: Compositional matrix adjust. Identities = 89/228 (39%), Positives = 126/228 (55%), Gaps = 16/228 (7%) Query: 7 GGDYIADSKEVMVVTETGRLPVYYFPLKDVNAALFQPSEKLATHPQK---GIQTFWDITS 63 G + D+ V E P YY PL DV + HPQ+ G + S Sbjct: 27 GHVLVFDTSAARYVWEVPYYPQYYIPLADVRMEFLRDE----NHPQRVQLGPSRLHSLVS 82 Query: 64 GGRTARNA--VWTYSGPQPEAHFLHGYVSFSWSKMDGWFEEEEEVFVHARDPYTRVDAIP 121 G+T R+A V+ G P A G V F+W + WFEE+E ++ H R+PY R DA+ Sbjct: 83 AGQTHRSAARVFDVDGDSPVA----GTVRFNWDPLR-WFEEDEPIYGHPRNPYQRADALR 137 Query: 122 ASRHVQLEVNGIIVADSRRPVILYETGLTPRYYLPAEDVRLDLLQENPNSTRCPYKGIAT 181 + RHV++E++GI++AD+R PV+L+ETG+ RYY+ D+ + L+ T CPYKG + Sbjct: 138 SHRHVRVELDGIVLADTRSPVLLFETGIPTRYYIDPADIAFEHLEPTSTQTLCPYKGTTS 197 Query: 182 -YWTAAVNGREYEDLVWSYKEPLPEVHEIAGLLCFYHEAADALYVDGI 228 YW+ V + DL W+Y PLP V IAGL+ FY+E D L VDG+ Sbjct: 198 GYWSVRVGDAVHRDLAWTYHYPLPAVAPIAGLVAFYNEKVD-LTVDGV 244 >MT1085 [S] COG2343 Uncharacterized protein conserved in bacteria Length = 254 Score = 153 bits (386), Expect = 3e-37, Method: Compositional matrix adjust. Identities = 89/228 (39%), Positives = 126/228 (55%), Gaps = 16/228 (7%) Query: 7 GGDYIADSKEVMVVTETGRLPVYYFPLKDVNAALFQPSEKLATHPQK---GIQTFWDITS 63 G + D+ V E P YY PL DV + HPQ+ G + S Sbjct: 27 GHVLVFDTSAARYVWEVPYYPQYYIPLADVRMEFLRDE----NHPQRVQLGPSRLHSLVS 82 Query: 64 GGRTARNA--VWTYSGPQPEAHFLHGYVSFSWSKMDGWFEEEEEVFVHARDPYTRVDAIP 121 G+T R+A V+ G P A G V F+W + WFEE+E ++ H R+PY R DA+ Sbjct: 83 AGQTHRSAARVFDVDGDSPVA----GTVRFNWDPLR-WFEEDEPIYGHPRNPYQRADALR 137 Query: 122 ASRHVQLEVNGIIVADSRRPVILYETGLTPRYYLPAEDVRLDLLQENPNSTRCPYKGIAT 181 + RHV++E++GI++AD+R PV+L+ETG+ RYY+ D+ + L+ T CPYKG + Sbjct: 138 SHRHVRVELDGIVLADTRSPVLLFETGIPTRYYIDPADIAFEHLEPTSTQTLCPYKGTTS 197 Query: 182 -YWTAAVNGREYEDLVWSYKEPLPEVHEIAGLLCFYHEAADALYVDGI 228 YW+ V + DL W+Y PLP V IAGL+ FY+E D L VDG+ Sbjct: 198 GYWSVRVGDAVHRDLAWTYHYPLPAVAPIAGLVAFYNEKVD-LTVDGV 244 >alr4241 [S] COG2343 Uncharacterized protein conserved in bacteria Length = 359 Score = 80.5 bits (197), Expect = 2e-15, Method: Compositional matrix adjust. Identities = 8/125 (6%), Positives = 18/125 (14%), Gaps = 4/125 (3%) Query: 103 EEEVFVHARDPYTRVDAIPASRHVQLEVNGIIVADSRRPVILYETGLTPRYYLPAEDVRL 162 + A + ++ N L + L Sbjct: 12 ALRHNLQRLRE--LAPA--SKMVAVVKANAYGHGLLETARTLPDADAFGVARLEEALRLR 67 Query: 163 DLLQENPNSTRCPYKGIATYWTAAVNGREYEDLVWSYKEPLPEVHEIAGLLCFYHEAADA 222 P + T + L E + + Sbjct: 68 AGGITKPVLLLEGFFDARDLPTISAQHFHTAVHNEEQLAALEEASLDEPVTVWMKLDTGM 127 Query: 223 LYVDG 227 + Sbjct: 128 HRLGV 132 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.318 0.136 0.428 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 19,959,562 Number of extensions: 820376 Number of successful extensions: 1217 Number of sequences better than 1.0e-05: 14 Number of HSP's gapped: 1201 Number of HSP's successfully gapped: 19 Length of query: 249 Length of database: 38,378,431 Length adjustment: 104 Effective length of query: 145 Effective length of database: 26,383,695 Effective search space: 3825635775 Effective search space used: 3825635775 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 114 (48.5 bits)