BLASTP 2.2.18 [Mar-02-2008]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment: Altschul, Stephen F., 
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= 0520.0032.p
         (554 letters)

Database: COG 
           115,334 sequences; 38,378,431 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

FN1401 [E] COG2987 Urocanate hydratase                                456   e-128
FN0792 [E] COG2987 Urocanate hydratase                                227   3e-59

>FN1401 [E] COG2987 Urocanate hydratase
          Length = 346

 Score =  456 bits (1172), Expect = e-128,   Method: Compositional matrix adjust.
 Identities = 0/523 (0%), Positives = 0/523 (0%), Gaps = 7/523 (1%)

Query: 11  ALRCKGWRQEALLRMLENVLENGENQRELIVYASLGKAARNWPSYLAIVDTLKRLEEDET 70
               +     A    L +V E                   NW +     + L    +   
Sbjct: 31  DAHAQLDYAVAQGINLIDVAEMYPVPPRPETQGLTETYVGNWLAKHGSREKLIIASKVSG 90

Query: 71  LVIQSGKPIGVFKTHRQAPLVVMANCNLVGRWATSENFYELQDKGLIIWGGLTAAAWQYI 130
               + K I   +   +  +    + +L      ++     Q                  
Sbjct: 91  PSRNNDKGIRPDQALDRKNIREALHDSLKR--LQTDYLDLYQVHWPQRPTNCFGKLGYSW 148

Query: 131 GSQGVIQGTYEIFQSIARLHFGGNLRGRFILTAGLGGMGGAQPLAGTLAGAAILCVEVAE 190
                     +   ++A     G +R   +      G+     LA       I+ ++   
Sbjct: 149 TDSAPAVSLLDTLDALAEYQRAGKIRYIGVSNETAFGVMRYLHLADKHDLPRIVTIQNPY 208

Query: 191 ERIDKRIAAGYLQRKTDSLDEALAWIEIARRSGESVSVGLLGNAAEVYPELLRRGVQPDV 250
             +++    G  +       E LA+  +   +     +     A        R       
Sbjct: 209 SLLNRSFEVGLAEVSQYEGVELLAYSCLGFGTLTGKYLNGAKPAGARNTLFSRFTRYSGE 268

Query: 251 VTDQTSAHDLLYGYIPEGYTPASAAAARKEDPARLQAAAGASIALEVKAMLQFKERGAIV 310
            T +  A  +       G  PA  A A       + +    +  ++            + 
Sbjct: 269 QTQKAVAAYVD-IARRHGLDPAQMALAFVRRQPFVASTLLGATTMDQLKTNIESLHLELS 327

Query: 311 FDNGNNIRSQAVQHGVP--DAFEIDIFTEAFLRPLFAKAIGPFRWIALSGEPQDIRIIDE 368
            D    I +    +  P                                           
Sbjct: 328 EDVLAEIEAVHQVYTYPAP                                          387

Query: 369 LILQEFSDNEIVTNWIKLANDHIPFEGLPARIGWFGHKDRSRLAVAVNELVREGRLAGPV 428
                                                                       
Sbjct: 388                                                              447

Query: 429 AFSRDHLDAAAMAHPNIMTERMKDGSDAVSDWPLLNAMLNCSSMADLVAIHSGGGGYAGY 488
                                                                       
Sbjct: 448 --                                                           505

Query: 489 MTSAGVTIVADGTADSGLRLRTALDNDTGLGVLRYADAGYETS 531
                                                      
Sbjct: 506                                             548


>FN0792 [E] COG2987 Urocanate hydratase
          Length = 346

 Score =  227 bits (579), Expect = 3e-59,   Method: Compositional matrix adjust.
 Identities = 0/529 (0%), Positives = 0/529 (0%), Gaps = 22/529 (4%)

Query: 38  ELIVYASLGKAARNWPSYLAIVDTLKRLEEDETLVIQSGKPIGVFKTHRQAPLVVMANCN 97
             +      +   N    L    T           + +          R   +       
Sbjct: 126 LDLYQVHWPQRPTNCFGKLGYSWTDSAPAVSLLDTLDALAEYQRAGKIRYIGVSNETAFG 185

Query: 98  LVGRWATSENFYELQDKGLIIWGGLTAAAWQYIGSQGVIQGTYEIFQSIARLHFG----G 153
           ++     ++     +   +     L   +++   ++       E+               
Sbjct: 186 VMRYLHLADKHDLPRIVTIQNPYSLLNRSFEVGLAEVSQYEGVELLAYSCLGFGTLTGKY 245

Query: 154 NLRGRFILTAGLGGMGGAQPLAGTLAGAAILCVEVAEERIDKRIAAGYLQRKTDSLDEAL 213
               +             +        A    V++A               +      + 
Sbjct: 246 LNGAKPAGARNTLFSRFTRYSGEQTQKAVAAYVDIARRHGLDPAQMALAFVRRQPFVAST 305

Query: 214 AWIEIARRSGESVSVGLLGNAAEVYPELLRRGVQPDVVTDQTSAHDLLY-GYIPEGYTPA 272
                                                                       
Sbjct: 306                                                              365

Query: 273 SAAAARKEDPARLQAAAGASIALEVKAMLQFKERGAIVFDNGNNIRSQAVQHGV------ 326
                                                                       
Sbjct: 366                                                              425

Query: 327 ----PDAFEIDIFTEAFLRP-LFAKAIGPFRWIALSGEPQDIRIIDELILQEFSDNEIVT 381
                                                                       
Sbjct: 426                                                              485

Query: 382 N-----WIKLANDHIPFEGLPARIGWFGHKDRSRLAVAVNELVREGRLAGPVAFSRDHLD 436
                                                                       
Sbjct: 486 -                                                            544

Query: 437 AAAMAHPNIMTERMKDGSDAVSDWPLLNAMLNCSSMADLVAIHSGGGGYAGYMTSAGVTI 496
                                                                       
Sbjct: 545                                                              604

Query: 497 VADGTADSGLRLRTALDNDTGLGVLRYADAGYETSLAEAANKEIDRVDT 545
                                                            
Sbjct: 605                                                   653


  Database: COG
    Posted date:  Aug 3, 2010  9:58 AM
  Number of letters in database: 38,378,431
  Number of sequences in database:  115,334
  
Lambda     K      H
   0.319    0.136    0.403 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 115334
Number of Hits to DB: 42,089,077
Number of extensions: 1805380
Number of successful extensions: 3936
Number of sequences better than 1.0e-05: 2
Number of HSP's gapped: 3927
Number of HSP's successfully gapped: 2
Length of query: 554
Length of database: 38,378,431
Length adjustment: 111
Effective length of query: 443
Effective length of database: 25,576,357
Effective search space: 11330326151
Effective search space used: 11330326151
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 118 (50.1 bits)