BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0520.0021.p (353 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value DR0205 [R] COG4586 ABC-type uncharacterized transport system, AT... 281 9e-76 DR1581 [R] COG4586 ABC-type uncharacterized transport system, AT... 242 5e-64 PH0913 [V] COG1131 ABC-type multidrug transport system, ATPase c... 168 1e-41 TVN0935 [V] COG1131 ABC-type multidrug transport system, ATPase ... 161 1e-39 STM1403 [R] COG0457 FOG: TPR repeat 155 1e-37 >DR0205 [R] COG4586 ABC-type uncharacterized transport system, ATPase component Length = 354 Score = 281 bits (720), Expect = 9e-76, Method: Compositional matrix adjust. Identities = 144/301 (47%), Positives = 190/301 (63%), Gaps = 14/301 (4%) Query: 32 RQYSEVTAVKDISFSIPQGEICGYIGENGAGKSTTIKMLTGILVPTSGTLSVGGYVPYEE 91 + ++ AV+DISFSIP GEI GY+G NGAGKSTTIK+LTG+LVP SG + VGG VP+++ Sbjct: 54 KSFARKPAVQDISFSIPAGEIVGYLGPNGAGKSTTIKVLTGLLVPDSGEVRVGGLVPWKQ 113 Query: 92 REKFVRNIGVVFGQRSQLWWDIGVIESFQLLRKVYRVPEQEFKKRLDELVERLELQDLLN 151 R + V +G VFGQR+ LWWD+ V ES +LLR VYRVP F + L E LEL LN Sbjct: 114 RRQHVARLGAVFGQRTTLWWDLPVRESLELLRHVYRVPAARFAENLAGFTELLELGPFLN 173 Query: 152 RPVRKLSLGQRMRCELVAALLHNPSILFLDEPTIGLDIVVKSEIRQFLKDMNREHGTTIL 211 P R LSLGQRMR +L AALLH+P +LFLDEPT+GLD+V K IR+F+K +N E G T+L Sbjct: 174 TPARALSLGQRMRADLAAALLHDPELLFLDEPTVGLDVVAKERIREFVKAVNAERGVTVL 233 Query: 212 LTTHDLQDIEALCSRVIMLDDGRIIYDGGLEDLKQRWGTGRE--VEFQFGTAXXXKLQQL 269 LTTHDL D+E L RV+M+D GR+++DG L +L+ R+G RE VEF+ A Sbjct: 234 LTTHDLGDVERLARRVMMIDTGRLLFDGPLAELQARYGGERELWVEFEKAPAQPALPGLT 293 Query: 270 MQWTEGMPVTWSSENDLGAKVWIPLELNVSDVLGLVVGQADITDIKIIETNTDDIVRSIY 329 + +G V + A + V A + D+ + E + +R IY Sbjct: 294 LLGQDGPRVRYGFSGAAAAPI------------AQVTALAPVRDLAVKEPEVEATIRRIY 341 Query: 330 Q 330 + Sbjct: 342 E 342 >DR1581 [R] COG4586 ABC-type uncharacterized transport system, ATPase component Length = 346 Score = 242 bits (618), Expect = 5e-64, Method: Compositional matrix adjust. Identities = 114/327 (34%), Positives = 203/327 (62%), Gaps = 8/327 (2%) Query: 3 AIQVQDLRKTFKVQKNREGLKGAFADLFKRQYSEVTAVKDISFSIPQGEICGYIGENGAG 62 A+ V+DL+K + V + GL G+ R+ V AVK +SF + GE+ G++G NGAG Sbjct: 9 AVHVRDLKKQYAVHEKDPGLAGSLRAFVSRKTRLVDAVKSVSFDLAPGEVVGFLGPNGAG 68 Query: 63 KSTTIKMLTGILVPTSGTLSVGGYVPYEEREKFVRNIGVVFGQRSQLWWDIGVIESFQLL 122 K+TT+KML+G+L P+ G++ V G+ P + +++R + +V GQ+ QL WD+ ++SF + Sbjct: 69 KTTTLKMLSGLLHPSGGSVEVLGFEPRRRQREYLRQMTLVMGQKQQLIWDLPALDSFLVN 128 Query: 123 RKVYRVPEQEFKKRLDELVERLELQDLLNRPVRKLSLGQRMRCELVAALLHNPSILFLDE 182 + +Y +P+ ++ + E E L L+ +L + VRKLSLG+RM+CEL AALLH P ILFLDE Sbjct: 129 QAIYEIPDAQYHATMREFTEVLGLEGILKKQVRKLSLGERMKCELAAALLHRPKILFLDE 188 Query: 183 PTIGLDIVVKSEIRQFLKDMNREHGTTILLTTHDLQDIEALCSRVIMLDDGRIIYDGGLE 242 PTIGLD+ ++ +R+F+++ NR+ T++LT+H + D+ AL R++++D G++++DG L Sbjct: 189 PTIGLDVNMQEAVREFVREYNRKEQATVMLTSHYMADVTALARRILVIDAGQLVFDGDLA 248 Query: 243 DLKQRWGTGREVEFQFGTAXXXKLQQLMQWTEGMPVTWSSENDLGAKVWIPLELNVSDVL 302 L ++ G+ + Q +QL + + S + L A++ +P VS Sbjct: 249 SLAEQGSGGKTIRLQLRRPVSA--EQLATYGD-----VSRSDGLSAELTVP-RREVSARA 300 Query: 303 GLVVGQADITDIKIIETNTDDIVRSIY 329 ++ + D+ D+ + + + + ++ ++ Sbjct: 301 ARLLNELDVADLTVEDPSIEAVMAELF 327 >PH0913 [V] COG1131 ABC-type multidrug transport system, ATPase component Length = 324 Score = 168 bits (426), Expect = 1e-41, Method: Compositional matrix adjust. Identities = 104/294 (35%), Positives = 165/294 (56%), Gaps = 23/294 (7%) Query: 32 RQYSEVTAVKDISFSIPQGEICGYIGENGAGKSTTIKMLTGILVPTSGTLSVGGYVPYEE 91 ++Y + AV+ ISF + +GEI ++G NGAGK+TT+ MLT +L PTSG V G+ +E Sbjct: 14 KKYGDFEAVRGISFKVRRGEIFAFLGPNGAGKTTTVHMLTTLLKPTSGRAIVAGHDVVKE 73 Query: 92 REKFVRNIGVVFGQRSQLWWDIGVIESFQLLRKVYRVPEQEFKKRLDELVERLELQDLLN 151 + + IGVVF Q + ++ E+ + ++Y + QE KK+++EL++ +EL + + Sbjct: 74 SREVRKKIGVVF-QDPSVDRELTAWENMYIHGRIYGLKGQELKKKIEELLKFVELWEFKD 132 Query: 152 RPVRKLSLGQRMRCELVAALLHNPSILFLDEPTIGLDIVVKSEIRQFLKDMNREHGTTIL 211 R V+ S G + R E+ AL+H P +LFLDEPTIGLD ++ I +++K M EH TI Sbjct: 133 RQVKYFSGGMQRRLEIARALIHEPEVLFLDEPTIGLDPQTRAHIWEYIKTMKEEHDMTIF 192 Query: 212 LTTHDLQDIEALCSRVIMLDDGRIIYDGGLEDLKQRWGTGREVEFQFGTAXXXKLQQLMQ 271 LTTH + + E L R+ ++D G+II +G E+LK+ G K ++ Sbjct: 193 LTTHYMDEAEQLADRIAIIDHGKIIAEGTAEELKKLVGND---------IIYVKFEK--- 240 Query: 272 WTEGMPVTWSSENDLGAKVW----IPLEL-NVSDVLGLVVGQADITDIKIIETN 320 P +E G KV + LE+ N ++ L LV +A ++KI+E Sbjct: 241 -----PTCIQAEFIRGCKVLNNGRVALEVKNAAEALPLVFEKAREMELKILEVT 289 >TVN0935 [V] COG1131 ABC-type multidrug transport system, ATPase component Length = 339 Score = 161 bits (408), Expect = 1e-39, Method: Compositional matrix adjust. Identities = 87/231 (37%), Positives = 145/231 (62%), Gaps = 2/231 (0%) Query: 28 DLFKRQYSEVTAVKDISFSIPQGEICGYIGENGAGKSTTIKMLTGILVPTSGTLSVGGYV 87 +L K + AV D++ I + EI G +G+NGAGK+TTIKMLT + PTSG V GY Sbjct: 18 NLTKIYSGNIKAVSDLNIEIEEAEIYGLLGKNGAGKTTTIKMLTTAIEPTSGNAKVAGYD 77 Query: 88 PYEEREKFVRNIGVVFGQRSQLWWDIGVIESFQLLRKVYRVPEQEFKKRLDELVERLELQ 147 ++REK +RNI V Q D+ IE+ +++ Y +P+ + R+++L+ ++L Sbjct: 78 LLKDREK-IRNIIGVVPQDLTTDADLKGIENLRMIAAFYDIPKSVAESRINDLLNIVDLT 136 Query: 148 DLLNRPVRKLSLGQRMRCELVAALLHNPSILFLDEPTIGLDIVVKSEIRQFLKDMNREHG 207 D N+ V + S G R R EL+ L++ P ILFLDEPT+GLD+ ++++ ++++D+ +E G Sbjct: 137 DWGNKYVSQYSGGMRKRLELICGLVNAPKILFLDEPTLGLDVNTRAKMWKYIRDIQKELG 196 Query: 208 TTILLTTHDLQDIEALCSRVIMLDDGRIIYDGGLEDLKQRWGTGREVEFQF 258 TI+LT+H L++++ L +R+ ++D G+I+ G ++LK G + QF Sbjct: 197 VTIILTSHYLEEVDELANRISIIDHGKILVTGTPDELKSSL-KGDIITMQF 246 >STM1403 [R] COG0457 FOG: TPR repeat Length = 673 Score = 155 bits (391), Expect = 1e-37, Method: Compositional matrix adjust. Identities = 15/218 (6%), Positives = 51/218 (23%), Gaps = 1/218 (0%) Query: 32 RQYSEVTAVKDISFSIPQGEICGYIGENGAGKSTTIKMLTGILVPTSGTLSVGGYVPYEE 91 + V + S I I G + + + + V Sbjct: 12 EFVTGPCLVLAGAGSGKTRVITNKIAHLIRGCGYQARHIAAVTFTNKAAREMKERVGQTL 71 Query: 92 REKFVRNIGVVFGQRSQLWWDIGVIESFQLLRKVYRVPEQEFKKRLDELVERLELQDLLN 151 K R + + + I + ++ + + + + L + + ++D Sbjct: 72 GRKEARGLMIST-FHTLGLDIIKREYAALGMKANFSLFDDTDQLALLKELTEGLIEDDKV 130 Query: 152 RPVRKLSLGQRMRCELVAALLHNPSILFLDEPTIGLDIVVKSEIRQFLKDMNREHGTTIL 211 + +S + +L S + + + + ++ + + Sbjct: 131 LLQQLISTISNWKNDLKTPSQAAASAIGERDRIFAHCYGLYDAHLKACNVLDFDDLILLP 190 Query: 212 LTTHDLQDIEALCSRVIMLDDGRIIYDGGLEDLKQRWG 249 + + + Y + Sbjct: 191 TLLLQANEEVRKRWQNKIRYLLVDEYQDTNTSQYELVK 228 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.319 0.138 0.400 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 26,407,371 Number of extensions: 1173216 Number of successful extensions: 8770 Number of sequences better than 1.0e-05: 2089 Number of HSP's gapped: 6253 Number of HSP's successfully gapped: 2338 Length of query: 353 Length of database: 38,378,431 Length adjustment: 107 Effective length of query: 246 Effective length of database: 26,037,693 Effective search space: 6405272478 Effective search space used: 6405272478 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 116 (49.3 bits)