BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0515.0009.p (272 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value PA5323 [E] COG0548 Acetylglutamate kinase 154 1e-37 NMA1275 [E] COG0548 Acetylglutamate kinase 152 4e-37 NMB1074 [E] COG0548 Acetylglutamate kinase 152 5e-37 MTH1836 [R] COG2018 Uncharacterized distant relative of homeotic... 151 1e-36 MTH1835_2 [R] COG1827 Predicted small molecule binding protein (... 151 1e-36 >PA5323 [E] COG0548 Acetylglutamate kinase Length = 252 Score = 154 bits (389), Expect = 1e-37, Method: Compositional matrix adjust. Identities = 0/272 (0%), Positives = 0/272 (0%), Gaps = 17/272 (6%) Query: 12 GGLFVMKCGGSTLAA--LPDSFFDDLRELQLSGAQPVIVHGGGPAISGNLEKLGIESSFV 69 L ++ + A S + +E+ Sbjct: 27 VPLENVEYVADLGCGPGNSTALLQQRWPAARITGIDSSPAMIAEARSALPDCQFVEADIR 86 Query: 70 NGLRVTTEEVLDVVEMTLAGSINKAIVRRIXXXXXXXXXXXXVDGRLITARLVANSXXXX 129 N V +++ + + + Sbjct: 87 NWQPVQALDLIFANASLQWLPDHYELFPHLVSLLNPQGVLAVQMPDNWLEPTHVLMREVA 146 Query: 130 XXXXXXXXNAEIVA-------GVLAM----GYIPVIAPIGVDAGGQRYNINADTAAGAVA 178 E +A + + + + T Sbjct: 147 WEQNYPDRGREPLAGVHAYYDILSEAGCEVDIWRTTYYHQMPSHQAIIDWVTATGLRPWL 206 Query: 179 SFIGSPQMIVVTDVPGIMRTLDGRKTVLPSVTVGQIEDLIKNGEIYGGMIPKVRAAIDCI 238 + + + M Sbjct: 207 QDLTESEQQLFLKRYHQM--- 263 Query: 239 QGSVSEVVIVDGKEPR-VLSRVLQGEKLGTRI 269 Sbjct: 264 295 >NMA1275 [E] COG0548 Acetylglutamate kinase Length = 252 Score = 152 bits (385), Expect = 4e-37, Method: Compositional matrix adjust. Identities = 0/254 (0%), Positives = 0/254 (0%), Gaps = 11/254 (4%) Query: 11 AGGLFVMKCGGSTLA--ALPDSFFDDLRELQLSGAQPVIVHGGGPAISGNLEKLGIESSF 68 V +++G + + Sbjct: 27 VPLENVEYVADLGCGPGNSTALLQQRWPAARITGIDSSPAMIAEARSALPDCQFVEADIR 86 Query: 69 VNGLRVTTEEVLDVVEMTLAGSINKAIVRRIXXXXXXXXXXXXVDGRLITARLV------ 122 + + + + + + + V Sbjct: 87 NWQPVQALDLIFANASLQWLPDHYELFPHLVSLLNPQGVLAVQMPDNWLEPTHVLMREVA 146 Query: 123 ANSXXXXXXXXXXXXNAEIVAGVLAMGYIPVIAPIGVDAGGQRYNINADTAAGAVASFIG 182 + G I + D Sbjct: 147 WEQNYPDRGREPLAGVHAYYDILSEAGCEVDIWRTTYYHQMPSHQAIIDWVTATGLRPWL 206 Query: 183 SPQMIVVTDVPGIMRTLDGRKTVLPSVTVGQIEDLIKNGEIYGGMIPKVRAAIDCIQGSV 242 + Sbjct: 207 QDLTESEQQLFLKR--- 263 Query: 243 SEVVIVDGKEPRVL 256 Sbjct: 264 277 >NMB1074 [E] COG0548 Acetylglutamate kinase Length = 252 Score = 152 bits (384), Expect = 5e-37, Method: Compositional matrix adjust. Identities = 0/254 (0%), Positives = 0/254 (0%), Gaps = 11/254 (4%) Query: 11 AGGLFVMKCGGSTLA--ALPDSFFDDLRELQLSGAQPVIVHGGGPAISGNLEKLGIESSF 68 V +++G + + Sbjct: 27 VPLENVEYVADLGCGPGNSTALLQQRWPAARITGIDSSPAMIAEARSALPDCQFVEADIR 86 Query: 69 VNGLRVTTEEVLDVVEMTLAGSINKAIVRRIXXXXXXXXXXXXVDGRLITARLV------ 122 + + + + + + + V Sbjct: 87 NWQPVQALDLIFANASLQWLPDHYELFPHLVSLLNPQGVLAVQMPDNWLEPTHVLMREVA 146 Query: 123 ANSXXXXXXXXXXXXNAEIVAGVLAMGYIPVIAPIGVDAGGQRYNINADTAAGAVASFIG 182 + G I + D Sbjct: 147 WEQNYPDRGREPLAGVHAYYDILSEAGCEVDIWRTTYYHQMPSHQAIIDWVTATGLRPWL 206 Query: 183 SPQMIVVTDVPGIMRTLDGRKTVLPSVTVGQIEDLIKNGEIYGGMIPKVRAAIDCIQGSV 242 + Sbjct: 207 QDLTESEQQLFLKR--- 263 Query: 243 SEVVIVDGKEPRVL 256 Sbjct: 264 277 >MTH1836 [R] COG2018 Uncharacterized distant relative of homeotic protein bithoraxoid Length = 268 Score = 151 bits (381), Expect = 1e-36, Method: Compositional matrix adjust. Identities = 0/270 (0%), Positives = 0/270 (0%), Gaps = 15/270 (5%) Query: 15 FVMKCGGSTL--AALPDSFFDDLRELQLSGAQPVIVHGGGPAISGNLEKLGIESSFVNGL 72 + + AA + + + + + + L Sbjct: 22 KIKTYKVVLIARAASIFGVKRIVIYHDDADGEARFIRDILTYMDTPQYLRRKVFPIMREL 81 Query: 73 RVTTEEVLDVVEMTLAGSINKAIVRRIXXXXXXXXXXXXVDGRLITAR-----LVANSXX 127 + G R+ G A V Sbjct: 82 KHVGILPPLRTPHHPTGKPVTGEYRQGLTVKRVKKGTLVDIGADKLALCREKLTVNRIMS 141 Query: 128 XXXXXXXXXXNAEIVA---GVLAM----GYIPVIAPIGVDAGGQRYNINADTAAGAVASF 180 E + + + + + Sbjct: 142 FRVVRLGKEILIEPDEPEDRYWGYEVLDTRRNLAESLKTVGADVVVATSRNASPITSILD 201 Query: 181 IGSPQMIVVTDVPGIMRTLDGRKTVLPSVTVGQIEDLIKNGEIYGGMIPKVRAAIDCIQG 240 +M + + + + + ++ + Sbjct: 202 EVKTRMRGAREAAILFGGPYKGLPEIDADIWVNTLPGQCTETVRTEEAVLATLSVFNMLT 261 Query: 241 SVSEVVIVDGK-EPRVLSRVLQGEKLGTRI 269 Sbjct: 262 291 >MTH1835_2 [R] COG1827 Predicted small molecule binding protein (contains 3H domain) Length = 268 Score = 151 bits (381), Expect = 1e-36, Method: Compositional matrix adjust. Identities = 0/270 (0%), Positives = 0/270 (0%), Gaps = 15/270 (5%) Query: 15 FVMKCGGSTL--AALPDSFFDDLRELQLSGAQPVIVHGGGPAISGNLEKLGIESSFVNGL 72 + + AA + + + + + + L Sbjct: 22 KIKTYKVVLIARAASIFGVKRIVIYHDDADGEARFIRDILTYMDTPQYLRRKVFPIMREL 81 Query: 73 RVTTEEVLDVVEMTLAGSINKAIVRRIXXXXXXXXXXXXVDGRLITAR-----LVANSXX 127 + G R+ G A V Sbjct: 82 KHVGILPPLRTPHHPTGKPVTGEYRQGLTVKRVKKGTLVDIGADKLALCREKLTVNRIMS 141 Query: 128 XXXXXXXXXXNAEIVA---GVLAM----GYIPVIAPIGVDAGGQRYNINADTAAGAVASF 180 E + + + + + Sbjct: 142 FRVVRLGKEILIEPDEPEDRYWGYEVLDTRRNLAESLKTVGADVVVATSRNASPITSILD 201 Query: 181 IGSPQMIVVTDVPGIMRTLDGRKTVLPSVTVGQIEDLIKNGEIYGGMIPKVRAAIDCIQG 240 +M + + + + + ++ + Sbjct: 202 EVKTRMRGAREAAILFGGPYKGLPEIDADIWVNTLPGQCTETVRTEEAVLATLSVFNMLT 261 Query: 241 SVSEVVIVDGK-EPRVLSRVLQGEKLGTRI 269 Sbjct: 262 291 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.319 0.139 0.387 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 18,090,198 Number of extensions: 755410 Number of successful extensions: 1765 Number of sequences better than 1.0e-05: 21 Number of HSP's gapped: 1734 Number of HSP's successfully gapped: 21 Length of query: 272 Length of database: 38,378,431 Length adjustment: 105 Effective length of query: 167 Effective length of database: 26,268,361 Effective search space: 4386816287 Effective search space used: 4386816287 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 115 (48.9 bits)