BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0515.0006.p (322 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value PA3537 [E] COG0078 Ornithine carbamoyltransferase 342 6e-94 SMc02137 [E] COG0078 Ornithine carbamoyltransferase 305 6e-83 SA2427 [E] COG0078 Ornithine carbamoyltransferase 291 1e-78 Cgl1365 [E] COG0078 Ornithine carbamoyltransferase 279 4e-75 STM4465 [E] COG0078 Ornithine carbamoyltransferase 277 2e-74 >PA3537 [E] COG0078 Ornithine carbamoyltransferase Length = 305 Score = 342 bits (876), Expect = 6e-94, Method: Compositional matrix adjust. Identities = 168/303 (55%), Positives = 210/303 (69%), Gaps = 7/303 (2%) Query: 19 RDLLELNDYSPEEITYLIDLAIELKRKQKSGEVYQPLKGKTIGLIFEKSSTRTRVSFEVG 78 R L DYSPEE+ LI ELK + G +Y+PLK + +G++FEK+STRTR+SFE G Sbjct: 4 RHFLSFMDYSPEELIGLIRRGSELKDLRNRGVLYEPLKSRVLGMVFEKASTRTRLSFEAG 63 Query: 79 MYQLGGHALFLSKNDIQLGRGETVGDTAQVMSRYLDGIMIRTFGHDKVEDLARYASVPVI 138 M QLGG A+FLS D QLGRGE +GD+A+VMSR LDG+MIRTF H + + A ++ VPVI Sbjct: 64 MIQLGGQAIFLSPRDTQLGRGEPIGDSARVMSRMLDGVMIRTFAHATLTEFAAHSKVPVI 123 Query: 139 NGLSDLAHPCQVLADYQTVYEHKGKLKGLKLAYIGDGNNMAHSLLIGGAKLGVHVSVAGP 198 NGLSD HPCQ+LAD QT +EH+G ++G +A+IGDGNNM +S + K + VA P Sbjct: 124 NGLSDDLHPCQLLADMQTFHEHRGSIQGKTVAWIGDGNNMCNSYIEAALKFDFQLRVACP 183 Query: 199 EGYEPDAAVVAEAREIAKETGALIVVTRSPQEAVQDADVIYTDVWASMGFEAEQLAREAA 258 EGYEP A VA A G + V R P+EAV A ++ TDVWASMG E E AR A Sbjct: 184 EGYEPKAEFVALA-------GDRLRVVRDPREAVAGAHLVSTDVWASMGQEDEAAARIAL 236 Query: 259 FKDYQVNEELVKGAKSDYLFLHCLPAHREEEVSTGVIDGPNSVIFDQAENRLHAQKALMA 318 F+ YQVN L+ GA D LF+HCLPAHR EE+S ++D P SV +DQAENRLHAQKAL+ Sbjct: 237 FRPYQVNAALLDGAADDVLFMHCLPAHRGEEISEELLDDPRSVAWDQAENRLHAQKALLE 296 Query: 319 ALM 321 L+ Sbjct: 297 LLI 299 >SMc02137 [E] COG0078 Ornithine carbamoyltransferase Length = 303 Score = 305 bits (781), Expect = 6e-83, Method: Compositional matrix adjust. Identities = 153/305 (50%), Positives = 206/305 (67%), Gaps = 7/305 (2%) Query: 19 RDLLELNDYSPEEITYLIDLAIELKRKQKSGEVYQPLKGKTIGLIFEKSSTRTRVSFEVG 78 R L+L+ + ++ +ID A K K+G +PL GK + +IFEK STRTRVSF+VG Sbjct: 3 RHFLDLSAMTATDLRTIIDDARVRKSATKAGTAEKPLAGKMLAMIFEKPSTRTRVSFDVG 62 Query: 79 MYQLGGHALFLSKNDIQLGRGETVGDTAQVMSRYLDGIMIRTFGHDKVEDLARYASVPVI 138 M QLGG LFLS ++QLGR ET+GDTA+V+SRY+D IMIRT H ++ ++A +A+VPVI Sbjct: 63 MRQLGGETLFLSGTEMQLGRAETIGDTAKVLSRYVDAIMIRTTDHRRLLEMAEHATVPVI 122 Query: 139 NGLSDLAHPCQVLADYQTVYEHKGKLKGLKLAYIGDGNNMAHSLLIGGAKLGVHVSVAGP 198 NGL+D HPCQ++AD T EH+G +KG +A+ GDGNN+ HSL+ G A+ G +++A P Sbjct: 123 NGLTDDTHPCQIMADILTFEEHRGPVKGKTIAWTGDGNNVLHSLIEGSARFGYRMNMAVP 182 Query: 199 EGYEPDAAVVAEAREIAKETGALIVVTRSPQEAVQDADVIYTDVWASMGFEAEQLAR-EA 257 G EP + AR GA ++++ ++AV A + TD W SM E AR Sbjct: 183 LGSEPHDKFLNWAR----NNGAEVLLSHEAEQAVAGAHCVVTDTWISM--NQEHRARGHN 236 Query: 258 AFKDYQVNEELVKGAKSDYLFLHCLPAHREEEVSTGVIDGPNSVIFDQAENRLHAQKALM 317 F+ YQVN L+K A D LF+HCLPAHR EEV+ VIDGP SV+FD+AENRLHAQK+++ Sbjct: 237 VFQPYQVNGALMKHAAPDALFMHCLPAHRGEEVTDEVIDGPQSVVFDEAENRLHAQKSIL 296 Query: 318 AALMG 322 A MG Sbjct: 297 AWCMG 301 >SA2427 [E] COG0078 Ornithine carbamoyltransferase Length = 336 Score = 291 bits (744), Expect = 1e-78, Method: Compositional matrix adjust. Identities = 154/326 (47%), Positives = 204/326 (62%), Gaps = 19/326 (5%) Query: 16 LKGRDLLELNDYSPEEITYLIDLAIELKRKQKSGEVYQPLKGKTIGLIFEKSSTRTRVSF 75 LKGR LL+ +D++ E LID AI LK +K+G + L GK I L+FEK+STRTR +F Sbjct: 10 LKGRSLLKESDFTKAEFEGLIDFAITLKEYKKNGIKHHYLSGKNIALLFEKNSTRTRAAF 69 Query: 76 EVGMYQLGGHALFLSKNDIQLGRGETVGDTAQVMSRYLDGIMIRTFGHDKVEDLARYASV 135 V LG H FL KNDIQLG+ E+V DTA+V+ R DGI R F VEDLA+++ V Sbjct: 70 TVASIDLGAHPEFLGKNDIQLGKKESVEDTAKVLGRMFDGIEFRGFSQQAVEDLAKFSGV 129 Query: 136 PVINGLSDLAHPCQVLADYQTVYEHKGKLKGLKLAYIGDG-NNMAHSLLIGGAKLGVHVS 194 PV NGL+D HP Q+LAD+ T+ E+ G L+G+ L Y+GDG NN+AHSL++ GA LGV+V Sbjct: 130 PVWNGLTDDWHPTQMLADFMTIKENFGYLEGINLTYVGDGRNNIAHSLMVAGAMLGVNVR 189 Query: 195 VAGPEGYEPDAAVVAEAREIAKETGALIVVTRSPQEAVQDADVIYTDVWASMGFEAEQLA 254 + P+ P A V A+E A + G I++T + EAV++ D IYTDVW SMG E+E Sbjct: 190 ICTPKSLNPKEAYVDIAKEKASQYGGSIMITDNIAEAVENTDAIYTDVWVSMGEESEFEQ 249 Query: 255 REAAFKDYQVNEELVK-GAKSDYLFLHCLPAHR-----------------EEEVSTGVID 296 R KDYQVN+++ K +FLHCLPA E EV+ + Sbjct: 250 RINLLKDYQVNQQMFDLTGKDSTIFLHCLPAFHDTNTLYGQEIYEKYGLAEMEVTDQIFR 309 Query: 297 GPNSVIFDQAENRLHAQKALMAALMG 322 +S +FDQAENR+H KA+MAA +G Sbjct: 310 SEHSKVFDQAENRMHTIKAVMAATLG 335 >Cgl1365 [E] COG0078 Ornithine carbamoyltransferase Length = 319 Score = 279 bits (713), Expect = 4e-75, Method: Compositional matrix adjust. Identities = 145/319 (45%), Positives = 206/319 (64%), Gaps = 12/319 (3%) Query: 12 IAQQLKGRDLLELNDYSPEEITYLIDLAIELKRKQKSGEVYQPLKG-KTIGLIFEKSSTR 70 + Q + R L +D +P E ++ LA +LK S +PL+G K++ ++F+K+STR Sbjct: 1 MTSQPQVRHFLADDDLTPAEQAEVLTLAAKLKAAPFS---ERPLEGPKSVAVLFDKTSTR 57 Query: 71 TRVSFEVGMYQLGGHALFLSKNDIQLGRGETVGDTAQVMSRYLDGIMIRTFGHDKVEDLA 130 TR SF+ G+ LGGHA+ + Q+G+GE++ DTA V+SRY++ I+ RT+ H +A Sbjct: 58 TRFSFDAGIAHLGGHAIVVDSGSSQMGKGESLQDTAAVLSRYVEAIVWRTYAHSNFHAMA 117 Query: 131 RYASVPVINGLSDLAHPCQVLADYQTVYEH------KGKLKGLKLAYIGDG-NNMAHSLL 183 ++VP++N LSD HPCQ+LAD QT+ E+ LKG K Y+GDG NNMA+S + Sbjct: 118 ETSTVPLVNSLSDDLHPCQILADLQTIVENLSPEEGPAGLKGKKAVYLGDGDNNMANSYM 177 Query: 184 IGGAKLGVHVSVAGPEGYEPDAAVVAEAREIAKETGALIVVTRSPQEAVQDADVIYTDVW 243 IG A G+ +S+ PEG++P A V A + +ETGA +VVT S E V ADV+ TD W Sbjct: 178 IGFATAGMDISIIAPEGFQPRAEFVERAEKRGQETGAKVVVTDSLDE-VAGADVVITDTW 236 Query: 244 ASMGFEAEQLAREAAFKDYQVNEELVKGAKSDYLFLHCLPAHREEEVSTGVIDGPNSVIF 303 SMG E + + R F YQVN+E++ A +FLHCLPA+R +EV+ VIDGP S +F Sbjct: 237 VSMGMENDGIDRTTPFVPYQVNDEVMAKANDGAIFLHCLPAYRGKEVAASVIDGPASKVF 296 Query: 304 DQAENRLHAQKALMAALMG 322 D+AENRLHAQKAL+ L+ Sbjct: 297 DEAENRLHAQKALLVWLLA 315 >STM4465 [E] COG0078 Ornithine carbamoyltransferase Length = 334 Score = 277 bits (708), Expect = 2e-74, Method: Compositional matrix adjust. Identities = 152/329 (46%), Positives = 201/329 (61%), Gaps = 22/329 (6%) Query: 16 LKGRDLLELNDYSPEEITYLIDLAIELKRKQKSGEVYQPLKGKTIGLIFEKSSTRTRVSF 75 LK R+ L+L DY+P EI +LIDLAIELK +K+G Q L GK I LIFEK+STRTR +F Sbjct: 5 LKNRNFLKLLDYTPAEIQHLIDLAIELKAAKKAGCEKQTLIGKNIALIFEKTSTRTRCAF 64 Query: 76 EVGMYQLGGHALFLSKNDIQLGRGETVGDTAQVMSRYLDGIMIRTFGHDKVEDLARYASV 135 EV + G +L + Q+G E++ DTA+V+ R DGI R FG VE+L YA V Sbjct: 65 EVAAFDQGAQVTYLGPSGSQIGHKESMKDTARVLGRMYDGIEYRGFGQHIVEELGEYAGV 124 Query: 136 PVINGLSDLAHPCQVLADYQTVYEH-KGK-LKGLKLAYIGDG-NNMAHSLLIGGAKLGVH 192 PV NGL+D HP Q+LAD T+ EH GK L L AY+GD NNM +SL++G AK+G+ Sbjct: 125 PVWNGLTDEFHPTQILADLMTMLEHAPGKTLPELSFAYLGDARNNMGNSLMVGAAKMGMD 184 Query: 193 VSVAGPEGYEPDAAVVAEAREIAKETGALIVVTRSPQEAVQDADVIYTDVWASMGFEAEQ 252 + + P+ + PDAA+VA+ REIA TGA I +T S ++ V D +YTDVW SMG E Sbjct: 185 IRLIAPKSFWPDAALVAQCREIASVTGARITLTESVEDGVHGVDFLYTDVWVSMGEPKEA 244 Query: 253 LA-REAAFKDYQVNEELVKGA-KSDYLFLHCLPAHREE-----------------EVSTG 293 A R + YQVN+++V D F+HCLPA E EV+ Sbjct: 245 WAERVSLMTPYQVNQQVVNATGNPDVKFMHCLPAFHNEHTKVGREIEMAYGLKGLEVTEE 304 Query: 294 VIDGPNSVIFDQAENRLHAQKALMAALMG 322 V + S++FD+AENR+H KA+M A +G Sbjct: 305 VFESAGSIVFDEAENRMHTIKAVMVATLG 333 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.316 0.134 0.374 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 23,510,761 Number of extensions: 1056516 Number of successful extensions: 3599 Number of sequences better than 1.0e-05: 24 Number of HSP's gapped: 3525 Number of HSP's successfully gapped: 24 Length of query: 322 Length of database: 38,378,431 Length adjustment: 106 Effective length of query: 216 Effective length of database: 26,153,027 Effective search space: 5649053832 Effective search space used: 5649053832 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.6 bits) S2: 116 (49.3 bits)