BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0512.0011.p (263 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value MA1345 [V] COG1680 Beta-lactamase class C and other penicillin b... 180 2e-45 SA2230 [V] COG1680 Beta-lactamase class C and other penicillin b... 109 6e-24 BS_pbpX [V] COG1680 Beta-lactamase class C and other penicillin ... 100 4e-21 Rv1730c [V] COG1680 Beta-lactamase class C and other penicillin ... 99 1e-20 MT1771 [V] COG1680 Beta-lactamase class C and other penicillin b... 97 2e-20 >MA1345 [V] COG1680 Beta-lactamase class C and other penicillin binding proteins Length = 252 Score = 180 bits (456), Expect = 2e-45, Method: Compositional matrix adjust. Identities = 0/199 (0%), Positives = 0/199 (0%), Gaps = 10/199 (5%) Query: 9 DKAGVEAFATQFFEQKEVKEQLAGALLVIVKDGQVLLNKGYGYADIAAKRPVDADTTLFR 68 EA + Q + + + + + + + Sbjct: 65 PAMIAEARSALPDCQFVEADIRNWQPVQALDLIFANASLQWLPDHYELFPHLVSLLNPQG 124 Query: 69 LASVSKLFTAAGIMQLAEAGKVDLDKDVQTYLPDLKIPNTTGAPLTLKHLMTHTTGFDNA 128 + +V + L + L+ Sbjct: 125 VLAVQMPDNWLEPTHVLMREVAWEQNYPDRGREPLAGVHAYYDILSEAGCEVDIWRTT-- 182 Query: 129 DNVDSDRSYT--------LKNYLNDMMPTVVRKPGEVFRYDNFAFTLQGYIIEQVSGLPF 180 + ++ + Q+ Sbjct: 183 YYHQMPSHQAIIDWVTATGLRPWLQDLTESEQQLFLKRYHQMLEEQYPLQENGQILLAFP 242 Query: 181 QDYVSKNIFNPLGMDSSSF 199 Sbjct: 243 261 >SA2230 [V] COG1680 Beta-lactamase class C and other penicillin binding proteins Length = 252 Score = 109 bits (272), Expect = 6e-24, Method: Compositional matrix adjust. Identities = 7/187 (3%), Positives = 33/187 (17%), Gaps = 8/187 (4%) Query: 19 QFFEQKEVKEQLAGALLVIVKDGQVLLNKGYGYADIAAKRPVDADTTLFRLASVSKLFTA 78 ++ + + + + L + + Sbjct: 45 STALLQQRWPAARITGIDSSPAMIAEARSALPDCQF-VEADIRNWQPVQALDLIFANASL 103 Query: 79 AGIMQLAEAGKVDLDKDVQTYLPDLKIP-NTTGAPLTLKHLMTHTTGFDNADNVDSDRSY 137 + E + + +++P N L + + + Sbjct: 104 QWLPDHYELFPHLVSLLNPQGVLAVQMPDNWLEPTHVLMREVAWEQNYP-DRGREPLAGV 162 Query: 138 TLKNYLNDMMPTVV-----RKPGEVFRYDNFAFTLQGYIIEQVSGLPFQDYVSKNIFNPL 192 + V ++ + + + + + Sbjct: 163 HAYYDILSEAGCEVDIWRTTYYHQMPSHQAIIDWVTATGLRPWLQDLTESEQQLFLKRYH 222 Query: 193 GMDSSSF 199 M + Sbjct: 223 QMLEEQY 229 >BS_pbpX [V] COG1680 Beta-lactamase class C and other penicillin binding proteins Length = 252 Score = 99.8 bits (247), Expect = 4e-21, Method: Compositional matrix adjust. Identities = 0/166 (0%), Positives = 0/166 (0%), Gaps = 11/166 (6%) Query: 36 VIVKDGQVLLNKGYGYADIAAKRPVDAD-TTLFRLASVSKLFTAAGIMQLAEAGKVDLDK 94 + + + + + + + + Sbjct: 100 NASLQWLPDHYELFPHLV--SLLNPQGVLAVQMPDNWLEPTHVLMREVAWEQNYPDRGRE 157 Query: 95 DVQTYLPDLKIPNTTGAPLTLKHLMTHTTGFDNADNVDSDRSYTLKNYLNDM-MPTVVRK 153 + + + + TT + + + Sbjct: 158 PLAGVHAYY--DI--LSEAGCEVDIWRTTYYHQ--MPSHQAIIDWVTATGLRPWLQDLTE 211 Query: 154 PGEVFRYDNFAFTLQGYIIEQVSGLPFQDYVSKNIFNPLGMDSSSF 199 Sbjct: 212 SE- 256 >Rv1730c [V] COG1680 Beta-lactamase class C and other penicillin binding proteins Length = 252 Score = 98.6 bits (244), Expect = 1e-20, Method: Compositional matrix adjust. Identities = 11/180 (6%), Positives = 24/180 (13%), Gaps = 8/180 (4%) Query: 30 LAGALLVIVKDGQVLLNKGYGYADIAAKRPVDADTTLFRLASVSKLFTAAGIMQLAEAGK 89 A V+ + D+ L + + Sbjct: 73 SALPDCQFVEADIRNW-QPVQALDLIFANASLQWL-PDHYELFPHLVSLLNPQGVLAVQM 130 Query: 90 VDLDKDVQTYLPDLKIPN-TTGAPLTLKHLMTHTTGFDNADNVDSDRS-YTLKNYLNDM- 146 D + L H ++ T + Sbjct: 131 PDNWLEPTHVLMREVAWEQNYPDRGREPLAGVHAYYDILSEAGCEVDIWRTTYYHQMPSH 190 Query: 147 -MPTVVRKPGEVFRYDNFAFTLQGYIIEQVSGLPFQDYVSKNIFNPLGMDSSSFIFNDKV 205 R T + + N + + Sbjct: 191 QAIIDW-VTATGLRPWLQDLTESEQQLFLKRYHQMLEEQYPLQENGQILLAFPR-LFIVA 248 >MT1771 [V] COG1680 Beta-lactamase class C and other penicillin binding proteins Length = 252 Score = 97.4 bits (241), Expect = 2e-20, Method: Compositional matrix adjust. Identities = 0/180 (0%), Positives = 0/180 (0%), Gaps = 8/180 (4%) Query: 30 LAGALLVIVKDGQVLLNKGYGYADIAAKRPVDADTTLFRLASVSKLFTAAGIMQLAEAGK 89 ++ + + + + + + Sbjct: 95 DLIFANASLQWLPDHY-ELFPHLVSLLNPQGVLAV-QMPDNWLEPTHVLMREVAWEQNYP 152 Query: 90 VDLDKDVQTYLPDLKIPN-TTGAPLTLKHLMTHTTGFDNADNVDSDRS-YTLKNYLNDM- 146 + + I + + H A + Sbjct: 153 DRGREPLAGVHAYYDILSEAGCEVDIWRTTYYHQMPSHQAIIDWVTATGLRPWLQDLTES 212 Query: 147 -MPTVVRKPGEVFRYDNFAFTLQGYIIEQVSGLPFQDYVSKNIFNPLGMDSSSFIFNDKV 205 + Sbjct: 213 EQQLFL-- 270 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.317 0.134 0.386 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 19,147,279 Number of extensions: 756857 Number of successful extensions: 1315 Number of sequences better than 1.0e-05: 50 Number of HSP's gapped: 1261 Number of HSP's successfully gapped: 50 Length of query: 263 Length of database: 38,378,431 Length adjustment: 104 Effective length of query: 159 Effective length of database: 26,383,695 Effective search space: 4195007505 Effective search space used: 4195007505 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 115 (48.9 bits)