BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0510.0012.p (269 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value mll4093 [E] COG1305 Transglutaminase-like enzymes, putative cyst... 62 7e-10 PAB1274_1 [E] COG1305 Transglutaminase-like enzymes, putative cy... 60 5e-09 MTH357_3 [E] COG1305 Transglutaminase-like enzymes, putative cys... 57 3e-08 MTH359_2 [E] COG1305 Transglutaminase-like enzymes, putative cys... 55 1e-07 MTH412_2 [E] COG1305 Transglutaminase-like enzymes, putative cys... 52 1e-06 >mll4093 [E] COG1305 Transglutaminase-like enzymes, putative cysteine proteases Length = 252 Score = 62.4 bits (150), Expect = 7e-10, Method: Compositional matrix adjust. Identities = 8/211 (3%), Positives = 28/211 (13%), Gaps = 29/211 (13%) Query: 73 SKPNETFPLQQGNGSYKISVLENTTGNKYKVM---SSET-------VDLSMSDANDVYLS 122 + I + ++ Sbjct: 44 NSTALLQQRWPAARITGIDSSPAMIAEARSALPDCQFVEADIRNWQPVQALDLIFANASL 103 Query: 123 SVQNVKWSSSDKSVLKAAQLTQGLTTDEQKVKAIYNYIVSNVKYDYSLASSVTTDYIPNN 182 + V + ++ V ++ + + Sbjct: 104 QWLPDHYELFPHLVSLLNPQGVLAVQMPDNWLEPTHVLMREVAWEQNYPDRGREPLAGVH 163 Query: 183 DNTLATKKGICYDYASLFATMLRSQGIPTKLVMGNTSYV--------TSYHAWNEVLLDG 234 I + + +V +E L Sbjct: 164 A-----YYDILSEAGCEVDIWRTTYYHQMPSHQAIIDWVTATGLRPWLQDLTESEQQLFL 218 Query: 235 KWVTIDTTVDAGLGKNNKETGLIKVASKYSA 265 K + ++ + Sbjct: 219 KRYHQMLE------EQYPLQENGQILLAFPR 243 >PAB1274_1 [E] COG1305 Transglutaminase-like enzymes, putative cysteine proteases Length = 252 Score = 59.7 bits (143), Expect = 5e-09, Method: Compositional matrix adjust. Identities = 0/118 (0%), Positives = 0/118 (0%), Gaps = 19/118 (16%) Query: 139 AAQLTQGLTTDEQKVKAIYNYIVSNVKYDYSLASSVTTDYIPNNDNT----LATKKGICY 194 A T ++ + Y L + Sbjct: 192 AIIDWVTATGLRPWLQDLTESEQQLFLKRYHQMLE-----EQYPLQENGQILLAFPRLFI 246 Query: 195 DYASLFATMLRSQGIPTKLVMG---------NTSYVTSYHAWNEVLLDGK-WVTIDTT 242 Sbjct: 247 304 >MTH357_3 [E] COG1305 Transglutaminase-like enzymes, putative cysteine proteases Length = 252 Score = 57.4 bits (137), Expect = 3e-08, Method: Compositional matrix adjust. Identities = 6/142 (4%), Positives = 19/142 (13%), Gaps = 16/142 (11%) Query: 120 YLSSVQNVKWSSSDKSVLKAAQLTQGLTTDEQKVKAIYNYIVSNVKYDYSLASSVTTDYI 179 ++ S + A E Sbjct: 1 MSDWNPSLYLHFSAERSR-PAVELLARVPLENVEYVADLGCGPGNSTALLQ----QRWP- 54 Query: 180 PNNDNTLATKKGICYDYASLFATMLRSQGIPTKLVMGNTSYV---TSYHAWNEVLLDGKW 236 T A + + + + + Sbjct: 55 -AARITGIDSSPAMIAEARSALPDCQFVEADIRNWQPVQALDLIFANASLQWLPDHYELF 113 Query: 237 VTIDTTVDAGLGKNNKETGLIK 258 + + N + ++ Sbjct: 114 PHLVSL------LNPQGVLAVQ 129 >MTH359_2 [E] COG1305 Transglutaminase-like enzymes, putative cysteine proteases Length = 252 Score = 55.1 bits (131), Expect = 1e-07, Method: Compositional matrix adjust. Identities = 6/126 (4%), Positives = 25/126 (19%), Gaps = 10/126 (7%) Query: 120 YLSSVQNVKWSSSDKSVLKAAQLTQGLTTDEQKVKAIYNYIVSNVKYDYSLASSVTTDYI 179 + + +S+ L + + + V + ++ Sbjct: 3 DWNPSLYLHFSAERSRPA-VELLARVPLENVEYVADLGCGPGNSTALLQQR----WPAA- 56 Query: 180 PNNDNTLATKKGICYDYASLFATMLRSQGIPTKLVMGNTSYVTS---YHAWNEVLLDGKW 236 ++ I ++L I + + + + Sbjct: 57 -RITGIDSSPAMIAEARSALPDCQFVEADIRNWQPVQALDLIFANASLQWLPDHYELFPH 115 Query: 237 VTIDTT 242 + Sbjct: 116 LVSLLN 121 >MTH412_2 [E] COG1305 Transglutaminase-like enzymes, putative cysteine proteases Length = 252 Score = 52.0 bits (123), Expect = 1e-06, Method: Compositional matrix adjust. Identities = 8/135 (5%), Positives = 26/135 (19%), Gaps = 11/135 (8%) Query: 139 AAQLTQGLTTDEQKVKAIYNYIVSNVKYDYSLASSVTTDYIPNNDNTLATKKGICYDYAS 198 L + + + V + ++ ++ I ++ Sbjct: 21 VELLARVPLENVEYVADLGCGPGNSTALLQQR----WPAA--RITGIDSSPAMIAEARSA 74 Query: 199 LFATMLRSQGIPTKLVMGNTSYV---TSYHAWNEVLLDGKWVTIDTTVDA-GLGK-NNKE 253 L I + + S + + + + Sbjct: 75 LPDCQFVEADIRNWQPVQALDLIFANASLQWLPDHYELFPHLVSLLNPQGVLAVQMPDNW 134 Query: 254 TGLIKVASKYSAAKF 268 V + A + Sbjct: 135 LEPTHVLMREVAWEQ 149 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.309 0.124 0.342 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 17,233,816 Number of extensions: 607903 Number of successful extensions: 2865 Number of sequences better than 1.0e-05: 12 Number of HSP's gapped: 2878 Number of HSP's successfully gapped: 12 Length of query: 269 Length of database: 38,378,431 Length adjustment: 105 Effective length of query: 164 Effective length of database: 26,268,361 Effective search space: 4308011204 Effective search space used: 4308011204 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.7 bits) S2: 115 (48.9 bits)