BLASTP 2.2.18 [Mar-02-2008]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment: Altschul, Stephen F., 
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= 0510.0008.p
         (1262 letters)

Database: COG 
           115,334 sequences; 38,378,431 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

all4349 [S] COG5542 Predicted integral membrane protein                70   2e-11
all4348 [S] COG5542 Predicted integral membrane protein                55   7e-07
YJR143c [O] COG1928 Dolichyl-phosphate-mannose--protein O-mannos...    51   1e-05

>all4349 [S] COG5542 Predicted integral membrane protein
          Length = 399

 Score = 70.5 bits (171), Expect = 2e-11,   Method: Compositional matrix adjust.
 Identities = 78/273 (28%), Positives = 121/273 (44%), Gaps = 26/273 (9%)

Query: 292 FADYPPGYLY-ILYVLSLIRGLFGFAHGSGGETLLFKLPAILSDLVLGWLIYRAGRTKLG 350
           FADY P YLY IL   +++ GL         + L  KL A+  D V  +  Y+  + K  
Sbjct: 78  FADYTPPYLYWILIAGTVLSGL--------PKILAIKLFAMSVDFVCAFFTYKIVKLKYP 129

Query: 351 SGM-AVGLMLLFLFNPAVLMDSAAWGQADSXXXXXXXXSILGASEQRFVRSAIFFALATL 409
            G  A+   +  + +P V+ +SA WGQ DS         I   S Q+ + + + F +A  
Sbjct: 130 EGRKAIFAFITVILSPVVIYNSALWGQCDSIYTTGLIACIYFLSIQKQLSALVSFGIALS 189

Query: 410 VKPQALIFTPVLLFAFYHHR-AWKQLAVGALYGLGIFAVLAAPFFWNNGG-IGGLIDLYK 467
            K QA+  +P+LL     +R  W  L +  L  + + A++ A   W  G  I  L+ +Y 
Sbjct: 190 FKLQAMFLSPLLLIFLIKNRIKWYYLPIPFL--VYLIAIMPA---WVAGRPIQELLLIYF 244

Query: 468 GTLSSYPYSTVNAFNLYALTDPLWASIDSMWLGITYRAWGFIFILAAVALASYYSFK-KD 526
              + Y     NA N+Y      W   +S  +       G I  + A+ L +Y  +K K 
Sbjct: 245 NQANKYKELAKNAPNIYQ-----WIPNNSYNIV---APLGVIITIFAIFLLTYVVYKSKL 296

Query: 527 RKELSKSFFIGMVLITIVFVFGTKMHERYMYPA 559
              L +   +   ++ +V     KMHERY YPA
Sbjct: 297 EITLDRLIHLATTIVLLVPYILPKMHERYFYPA 329


>all4348 [S] COG5542 Predicted integral membrane protein
          Length = 395

 Score = 55.5 bits (132), Expect = 7e-07,   Method: Compositional matrix adjust.
 Identities = 81/327 (24%), Positives = 141/327 (43%), Gaps = 35/327 (10%)

Query: 241 RWLYVVFGAALILRIWIGLTAQGYQNDMNTFIA-WGQRLVDLGPGKFYEEGYFADYPPGY 299
            +L +    A+I+R+   +      +D  +F+A W   + + G     + G FADY P Y
Sbjct: 30  NYLTISIICAVIIRL---ICVPNRSSDYTSFLAPWYDFIANNGGFSALKHG-FADYTPPY 85

Query: 300 LY-ILYVLSLIRGLFGFAHGSGGETLLFKLPAILSDLVLGWLIYRAGRTKLGSG-MAVGL 357
           LY I++  +L+ GL         +    KL A+  D V  +  Y+  + K   G   +  
Sbjct: 86  LYWIVFAATLLSGL--------PKIFSIKLFAMFVDFVCAFFTYKIVKLKYPQGRQPIFA 137

Query: 358 MLLFLFNPAVLMDSAAWGQADSXXXXXXXXSILGASEQRFVRSAIFFALATLVKPQALIF 417
            +  + +P V+ +SA WGQ DS         I     ++ + + + F +    K QA+  
Sbjct: 138 FITVILSPVVIYNSAIWGQCDSIYTTGLIACIYFLCIKKEIPALVSFGIGLSFKLQAMFL 197

Query: 418 TPVLLFAFYHHRA-WKQLAVGALYGLGIFAVLAAPFFWNNG-GIGGLIDLYKGTLSSYPY 475
           +P+LL      R  W  + +  L  L   A+L A   W  G  +  L+ +Y    + Y  
Sbjct: 198 SPLLLIMLLKQRIRWYYIPIIPLVYL--LAILPA---WFAGRPMSELLLVYFNQANKYKE 252

Query: 476 STVNAFNLYA-LTDPLWASIDSMWLGITYRAWGFIFILAAVALASYYSFKKDRKELSKSF 534
                 N+Y  + + L+  +  + L  T        I A + LA  Y   K + E+++  
Sbjct: 253 LAKAVPNIYQWIPNNLYNIVVPIGLIST--------IFAIILLA--YVVHKSKLEITQER 302

Query: 535 FIGMVLITIVFV--FGTKMHERYMYPA 559
            I +  I+++ +     KMH+RY YPA
Sbjct: 303 LIHLATISVLLLPYILPKMHQRYFYPA 329


>YJR143c [O] COG1928 Dolichyl-phosphate-mannose--protein O-mannosyl
            transferase
          Length = 762

 Score = 51.2 bits (121), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 41/167 (24%), Positives = 75/167 (44%), Gaps = 38/167 (22%)

Query: 1058 VIIPGVIYSLSFIPVLSVSADGYTFKGLIDAQKNMYNYHSQLVATHPFASSWWEWPFMKR 1117
            V IP V+  L F+            K  I+ QK+M+ ++++L + HPFAS  + WP    
Sbjct: 530  VYIPKVVKPLPFL------------KKWIETQKSMFEHNNKLSSEHPFASEPYSWPGSLS 577

Query: 1118 PVWFFSGGEGLPEGQVSSIVTMGNPLIWWTGIFAMLASVWFTI--------------KRK 1163
             V F++ G+     +   I  +GN + WW  + ++   V   +              K  
Sbjct: 578  GVSFWTNGD-----EKKQIYFIGNIIGWWFQVISLAVFVGIIVADLITRHRGYYALNKMT 632

Query: 1164 DKNLY----MIWIGFFSQYVPWMLVPRETFLYHYFAMVPFMILAIVY 1206
             + LY      ++ +   Y P+ L+ R+ FL+HY   +P  ++A ++
Sbjct: 633  REKLYGPLMFFFVSWCCHYFPFFLMARQKFLHHY---LPAHLIACLF 676


  Database: COG
    Posted date:  Aug 3, 2010  9:58 AM
  Number of letters in database: 38,378,431
  Number of sequences in database:  115,334
  
Lambda     K      H
   0.325    0.141    0.444 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 115334
Number of Hits to DB: 89,698,576
Number of extensions: 3752670
Number of successful extensions: 10541
Number of sequences better than 1.0e-05: 3
Number of HSP's gapped: 10540
Number of HSP's successfully gapped: 3
Length of query: 1262
Length of database: 38,378,431
Length adjustment: 118
Effective length of query: 1144
Effective length of database: 24,769,019
Effective search space: 28335757736
Effective search space used: 28335757736
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 122 (51.6 bits)