BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0509.0005.p (179 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value STM1147 [R] COG2110 Predicted phosphatase homologous to the C-te... 156 2e-38 PA3693 [R] COG2110 Predicted phosphatase homologous to the C-ter... 132 2e-31 mll7730 [R] COG2110 Predicted phosphatase homologous to the C-te... 130 1e-30 Rv1899c_2 [R] COG2110 Predicted phosphatase homologous to the C-... 70 1e-12 MT1950_2 [R] COG2110 Predicted phosphatase homologous to the C-t... 70 2e-12 >STM1147 [R] COG2110 Predicted phosphatase homologous to the C-terminal domain of histone macroH2A1 Length = 346 Score = 156 bits (395), Expect = 2e-38, Method: Compositional matrix adjust. Identities = 17/176 (9%), Positives = 29/176 (16%), Gaps = 4/176 (2%) Query: 3 ISACQGDITSWQGDMIVNASNSGLFGGGGVDGAIHRAGGPQIAEECAAIRRKQGGILPGE 62 S G + A G + + G Sbjct: 5 RIPHSSLEVSTLGLGTMTFGEQNSEADAHAQLDYAVAQGINLIDVAEMYPVPPRPETQGL 64 Query: 63 AAVTCAGKLPLLGIIHTVGPIWKGGGAGEIATLARCYLNSLDAACTQGARSIAFPNISTG 122 L G + K G +LD + A + + T Sbjct: 65 TETYVGNWLAKHGSREKLIIASKVSGPSRNNDKGIRPDQALDRKNIREALHDSLKRLQTD 124 Query: 123 VYNFPKALACQTALKTVVDYVKERGPGGHPLERIEFICFEKDNADLYEETLKRYSD 178 + + Q + D Y+ K Sbjct: 125 YLDLYQVHWPQRPTNCFGKLGYSWTDS----APAVSLLDTLDALAEYQRAGKIRYI 176 >PA3693 [R] COG2110 Predicted phosphatase homologous to the C-terminal domain of histone macroH2A1 Length = 346 Score = 132 bits (333), Expect = 2e-31, Method: Compositional matrix adjust. Identities = 4/167 (2%), Positives = 15/167 (8%), Gaps = 8/167 (4%) Query: 7 QGDITSWQGDMIVNASNSGLFGGGGVDGAIHRAGGPQIAEECAAIRRKQGGILPGEAAVT 66 + + + + + + P Sbjct: 8 HSSLEVSTLGLGTMTFGEQNSEADAHAQLDYAVAQGINLIDV----AEMYPVPPRPETQG 63 Query: 67 CAGKLPLLGIIHTVGPIWKGGGAGEIATLARCYLNSLDAACTQGARSIAFPNISTGVYNF 126 + + + S Sbjct: 64 LTETYVGNWLAKHGSREKLIIASKVSGPSRNNDKGIRPDQALDRKNIREALHDSLKRLQT 123 Query: 127 PKALACQTALKTVVDYVKERGPGGHPLERIEFICFEKDNADLYEETL 173 + G + L Sbjct: 124 D----YLDLYQVHWPQRPTNCFGKLGYSWTDSAPAVSLLDTLDALAE 166 >mll7730 [R] COG2110 Predicted phosphatase homologous to the C-terminal domain of histone macroH2A1 Length = 346 Score = 130 bits (326), Expect = 1e-30, Method: Compositional matrix adjust. Identities = 7/162 (4%), Positives = 15/162 (9%), Gaps = 8/162 (4%) Query: 8 GDITSWQGDMIVNASNSGLFGGGGVDGAIHRAGGPQIAEECAAIRRKQGGILPGEAAVTC 67 ++ +AE T Sbjct: 13 VSTLGLGTMTFGEQNSEADAHAQLDYAVAQGINLIDVAEMY----PVPPRPETQGLTETY 68 Query: 68 AGKLPLLGIIHTVGPIWKGGGAGEIATLARCYLNSLDAACTQGARSIAFPNISTGVYNFP 127 G I + Y Sbjct: 69 VGNWLAKHGSREKLIIASKVSGPSRNNDKGIRPDQALDRKNIREALHDSLKRLQTDYLDL 128 Query: 128 KALACQTALKTVVDYVKERGPGGHPLERIEFICFEKDNADLY 169 + + + +A Sbjct: 129 YQVHWPQRPTNCFGKLGYSWTD----SAPAVSLLDTLDALAE 166 >Rv1899c_2 [R] COG2110 Predicted phosphatase homologous to the C-terminal domain of histone macroH2A1 Length = 346 Score = 70.5 bits (171), Expect = 1e-12, Method: Compositional matrix adjust. Identities = 4/158 (2%), Positives = 17/158 (10%), Gaps = 12/158 (7%) Query: 1 VAISACQGDITSWQGDMIVNASNSGLFGGGGVDGAIHRAGGPQIAEECAAIRRKQGGILP 60 + + + + A + + P Sbjct: 2 QYHRIPHSSLEVSTLGLGTMTFGEQNSEADAHAQLDYAVAQGINLIDVA----EMYPVPP 57 Query: 61 GEAAVTCAGKLPLLGIIHTVGPIWKGGGAGEIATLARCYLNSLDAACTQGARSIAFPNIS 120 + + R + Sbjct: 58 RPETQGLTETYVGNWLAKHGSREKLIIASKVSGPSRNND--KGIRPDQALDRKNIREALH 115 Query: 121 TGVYNFPKALACQTALKTVVDYVKERGPGGHPLERIEF 158 + V + + + Sbjct: 116 DSLKRLQ----TDYLDLYQVHWPQRPTNCF--GKLGYS 147 >MT1950_2 [R] COG2110 Predicted phosphatase homologous to the C-terminal domain of histone macroH2A1 Length = 346 Score = 70.1 bits (170), Expect = 2e-12, Method: Compositional matrix adjust. Identities = 9/158 (5%), Positives = 21/158 (13%), Gaps = 12/158 (7%) Query: 1 VAISACQGDITSWQGDMIVNASNSGLFGGGGVDGAIHRAGGPQIAEECAAIRRKQGGILP 60 I ++++ + + G I P Sbjct: 4 HRIPHSSLEVSTLGLGTMTFGEQNSEADAHAQLDYAVAQGINLIDVAEM----YPVPPRP 59 Query: 61 GEAAVTCAGKLPLLGIIHTVGPIWKGGGAGEIATLARCYLNSLDAACTQGARSIAFPNIS 120 +T L + + + + S Sbjct: 60 ETQGLTETYVGNWLAKHGSREKLIIASKVSGPSRNNDKG--IRPDQALDRKNIREALHDS 117 Query: 121 TGVYNFPKALACQTALKTVVDYVKERGPGGHPLERIEF 158 + G L Sbjct: 118 LKRLQTD----YLDLYQVHWPQRPTNCFGK--LGYSWT 149 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.319 0.139 0.429 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 14,259,718 Number of extensions: 603316 Number of successful extensions: 933 Number of sequences better than 1.0e-05: 5 Number of HSP's gapped: 926 Number of HSP's successfully gapped: 5 Length of query: 179 Length of database: 38,378,431 Length adjustment: 100 Effective length of query: 79 Effective length of database: 26,845,031 Effective search space: 2120757449 Effective search space used: 2120757449 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 112 (47.8 bits)