BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0504.0042.p (484 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value CAC1652 [E] COG1027 Aspartate ammonia-lyase 551 e-157 CAC0274 [E] COG1027 Aspartate ammonia-lyase 404 e-112 STM0444 [GEPR] COG0477 Permeases of the major facilitator superf... 389 e-108 NMA1001 [G] COG1109 Phosphomannomutase 295 1e-79 PA0854 [C] COG0114 Fumarase 278 1e-74 >CAC1652 [E] COG1027 Aspartate ammonia-lyase Length = 470 Score = 551 bits (1421), Expect = e-157, Method: Compositional matrix adjust. Identities = 261/464 (56%), Positives = 350/464 (75%) Query: 5 SAYRMERDALGSLPVPQDAYYGIHTARAKENFAAGGRPANRKLMHAIARVKQAAAKVNGR 64 S +R+E+D LG +P+++YYGI++ RA ENF + N L++A+ VK+AAA + + Sbjct: 6 SDFRIEKDLLGEKNLPKESYYGINSLRAFENFNISNKKVNLNLIYAVVIVKKAAALAHKK 65 Query: 65 NHALPQQKVQAILAACEEILDGCLDAHLIVDAYQGGAGTSSNMNVNEVIANRAIELLGGS 124 L +K AI++AC++IL G D I ++ QGGAGTS+NMNVNEVIANRAIELL GS Sbjct: 66 LKELKDEKADAIISACDDILSGKFDDEFITNSLQGGAGTSTNMNVNEVIANRAIELLNGS 125 Query: 125 KGDYSIVHPIDDVNLHQSTNDVYPTALRIAVIPLLRQLAEELASLQEVFQVKEHEYADLL 184 KGDYSI+HPI+DVN+ QSTNDVYPTALRIA I LLR L++ L+ LQE FQ+KE++++D+L Sbjct: 126 KGDYSIIHPIEDVNMSQSTNDVYPTALRIAAIKLLRPLSDALSKLQESFQIKENDFSDIL 185 Query: 185 RLGRTQLMDALPILAGQSFGAYAKAAARDRWRLYKAEERLREINIGGTAVGTGMNAPLTY 244 LGRT+LMDALP++ GQ FGAYAKA ARDRWR+YK EERLREINIGG A+GTG+NA Y Sbjct: 186 MLGRTELMDALPMMVGQGFGAYAKAFARDRWRIYKVEERLREINIGGNAIGTGINASYDY 245 Query: 245 IYTIADELRELTGLGLCRSDFPMDGTQNMDVFVEVSGLLKAAAVNLLKISNDFRLLSSGP 304 I+T+ D L++LTGLGL RSD+PMD TQNMDVFVEVSGLLK+ AVNL+KISND RLL+SGP Sbjct: 246 IFTVTDILQDLTGLGLARSDYPMDVTQNMDVFVEVSGLLKSCAVNLIKISNDIRLLNSGP 305 Query: 305 AGGIGEYILPAVQAGSSIMPGKVNPVIAEMLGSVAMRVIADDTAVTLAAASGQLELNAFT 364 GGIGE+I+ VQAGSSIMPGKVNPVI EM +M+V+A+DTA++LA++ GQL+LNAF+ Sbjct: 306 VGGIGEFIVEEVQAGSSIMPGKVNPVICEMTAQTSMKVMANDTAISLASSFGQLQLNAFS 365 Query: 365 PVXXXXXXXXXXXXXHGIPLFRERCLSGLKLDEHRCREHVDRSGVLAAATITYLGYDNXX 424 P+ + + +FRE+C+ +K++E +C E+++ S L A + Y+GYD Sbjct: 366 PLIAESLLESLEILTNAVNVFREKCIDSIKINEEKCLENLEASTALVTALVHYIGYDKAS 425 Query: 425 XXXXXXXXSGRPLEQLLVEGGWMTEKQIQEVLHPLEVTKPGIPG 468 + + +LL+ +T+++I ++L+P E+TKPGIPG Sbjct: 426 IIAKKALKEKKSIRELLLLEKILTKEEIDKILNPYEITKPGIPG 469 >CAC0274 [E] COG1027 Aspartate ammonia-lyase Length = 465 Score = 404 bits (1039), Expect = e-112, Method: Compositional matrix adjust. Identities = 198/463 (42%), Positives = 290/463 (62%) Query: 7 YRMERDALGSLPVPQDAYYGIHTARAKENFAAGGRPANRKLMHAIARVKQAAAKVNGRNH 66 +R+E D++G VP++ YYG+ T R +NF G N + + ++ ++K+AAA N Sbjct: 3 FRIESDSIGDKKVPKEVYYGVQTLRGADNFKITGLRLNEEFIKSVVQIKKAAAITNLEIG 62 Query: 67 ALPQQKVQAILAACEEILDGCLDAHLIVDAYQGGAGTSSNMNVNEVIANRAIELLGGSKG 126 L +AI+ AC+E++ G + I+D QGGAGTS NMN NEVIANRAIE+LG KG Sbjct: 63 ELEVNIGKAIIKACDEVIAGKFNEDFIIDPIQGGAGTSINMNANEVIANRAIEILGYEKG 122 Query: 127 DYSIVHPIDDVNLHQSTNDVYPTALRIAVIPLLRQLAEELASLQEVFQVKEHEYADLLRL 186 +Y IVHP D VN+ QSTNDV PTA +I + L+ + ++L L F K ++ D++++ Sbjct: 123 NYRIVHPNDHVNMGQSTNDVIPTAGKITALRLVIKNLDKLKELSNAFSEKAEQFKDVIKM 182 Query: 187 GRTQLMDALPILAGQSFGAYAKAAARDRWRLYKAEERLREINIGGTAVGTGMNAPLTYIY 246 GRTQL DA+PI GQ F AY+ RD R+ KA++ L+ +NIGGTAVGTG+NA Y+ Sbjct: 183 GRTQLQDAVPITLGQEFSAYSAVVKRDIARIQKAQDELKVVNIGGTAVGTGINADSRYVD 242 Query: 247 TIADELRELTGLGLCRSDFPMDGTQNMDVFVEVSGLLKAAAVNLLKISNDFRLLSSGPAG 306 I L ++GL L ++D +DGTQN+D F +S +K A+NL KI+ND RL+SSGP Sbjct: 243 RIVPRLSFVSGLNLKKADDLIDGTQNLDSFASLSATIKTCALNLSKIANDLRLMSSGPRT 302 Query: 307 GIGEYILPAVQAGSSIMPGKVNPVIAEMLGSVAMRVIADDTAVTLAAASGQLELNAFTPV 366 G+GE LPA Q GSSIMPGKVNPVI E++ +A + +D A+++A +GQLELNAF PV Sbjct: 303 GLGEINLPAKQNGSSIMPGKVNPVIPEVINQIAFNIAGNDVAISMAVEAGQLELNAFEPV 362 Query: 367 XXXXXXXXXXXXXHGIPLFRERCLSGLKLDEHRCREHVDRSGVLAAATITYLGYDNXXXX 426 +G+ F + C+ + +E C E+V+ S + A Y+GY Sbjct: 363 IFYNIFESIQTLTNGVDTFIKNCILDITANEEICSEYVNNSVGIVTALCPYIGYAESAKI 422 Query: 427 XXXXXXSGRPLEQLLVEGGWMTEKQIQEVLHPLEVTKPGIPGR 469 SG ++++++ G + EK++ +++PL++TKPGI G+ Sbjct: 423 AKMAIKSGESIKKVVLREGVLKEKELNSIINPLKMTKPGIVGK 465 >STM0444 [GEPR] COG0477 Permeases of the major facilitator superfamily Length = 491 Score = 389 bits (1000), Expect = e-108, Method: Compositional matrix adjust. Identities = 28/414 (6%), Positives = 67/414 (16%), Gaps = 4/414 (0%) Query: 8 RMERDALGSLPVPQDAYYGIHTARAKENFAAGGRPANRKLMHAIARVKQAAAKVNGRNHA 67 + + P + +G A + + + + V Sbjct: 2 SSQYLRIFQQPRSAILLILGFASGLPLALTSGTLQAWMTVENIDLKTIGFFSLVGQAYVF 61 Query: 68 LPQQKVQAILAACEEILDGCLDAHLIVDAYQGGAGTSSNMNVNEVIANRAIELLGGSKGD 127 + L+ A ++ + R + L Sbjct: 62 KFLWSPLMDRYTPPFLGR--RRGWLLATQLLLLAAIAAMGFLEPGTQLRWMAALAVVIAF 119 Query: 128 YSIVHPIDDVNLHQSTNDVYPTALRIAVIPLLRQLAEELASLQEVFQVKEHEYADLLRLG 187 + ++ A I +L L S + + Sbjct: 120 C-SASQDIVFDAWKTDVLPAEERGAGAAISVLGYRLGMLVSGGLALWLADRWLGWQGMYW 178 Query: 188 RTQLMDALPILAGQSFGAYAKAAARDRWRLYKAEERLREINIGGTAVGTGMNAPLTYIYT 247 + I+A + LR+ A + L + Sbjct: 179 LMAALLIPCIIATLLAPEPTDTIPSPKSLEQAVVAPLRDFFGRNNAWLILLLIVLYKLGD 238 Query: 248 IADELRELTGLGLCRSDFPMDGTQNMDVFVEVSGLLKAAAVNLLKISNDFRLLSSGPAGG 307 T L + ++ ++ A +L Sbjct: 239 AFAMSLTTTFLIRGVGFDAGEVGVVNKTLGLLATIVGALYGGILMQRLSLFRALLIFGIL 298 Query: 308 IGEYILPAVQAGSSIMPGKVNPVIAEMLGSVAMRVIADDTAVTLAAASGQLELNAFTPVX 367 G + A A+ + + F + Sbjct: 299 QGASNAGYWLLSITDKNMFSMGAAVFFENLCGGMGTAAFVALLMTLCNKSFSATQFALLS 358 Query: 368 XXXXXXXXXXXXHGIPLFRERCLSGLKLDEHRCREHVDRSGVLAAATITYLGYD 421 +L + Sbjct: 359 ALSAVGRVYVGPVAGWFVEAH-GWPTFYLFSVVAAVPGLLLLLVCRQTLEYSWQ 411 >NMA1001 [G] COG1109 Phosphomannomutase Length = 346 Score = 295 bits (755), Expect = 1e-79, Method: Compositional matrix adjust. Identities = 0/459 (0%), Positives = 0/459 (0%), Gaps = 3/459 (0%) Query: 2 TDDSAYRMERDALGSLPVPQDAYYGIHTARAKENFAAGGRPANRKLMHAIARVKQAAAKV 61 +S ++ + G + + Sbjct: 25 EQNSEADAHAQLDYAVAQGINLIDVAEMYPVPPRPETQGLTETYVGNWLAKHGSREKLII 84 Query: 62 NGRNHALPQQKVQAILAACEEILDGCLDAHLIVDAYQGGAGTSSNMNVNEVIANRAIELL 121 + + + I +A L Sbjct: 85 ASKVSGPSRNNDKGIRPDQALDRKNIREALHDSLKRLQTDYLDLYQVHWPQRPTNCFGKL 144 Query: 122 GGSKGDYSIVHPIDDVNLHQSTNDVYPTALRIA-VIPLLRQLAEELASLQEVFQVKEHEY 180 G S D + + D + I + L + + Sbjct: 145 GYSWTDSAPAVSLLDTLDALAEYQRAGKIRYIGVSNETAFGVMRYLHLADKHDLPRIVTI 204 Query: 181 ADLLRLGRTQLMDALPILAGQSFGAYAKAAARDRWRLYKAEER-LREINIGGTAVGTGMN 239 + L L ++ A + + + + + + Sbjct: 205 QNPYSLLNRSFEVGLAEVSQYEGVELL-AYSCLGFGTLTGKYLNGAKPAGARNTLFSRFT 263 Query: 240 APLTYIYTIADELRELTGLGLCRSDFPMDGTQNMDVFVEVSGLLKAAAVNLLKISNDFRL 299 A M S LL A ++ LK + + Sbjct: 264 RYSGEQTQKAVAAYVDIARRHGLDPAQMALAFVRRQPFVASTLLGATTMDQLKTNIESLH 323 Query: 300 LSSGPAGGIGEYILPAVQAGSSIMPGKVNPVIAEMLGSVAMRVIADDTAVTLAAASGQLE 359 Sbjct: 324 383 Query: 360 LNAFTPVXXXXXXXXXXXXXHGIPLFRERCLSGLKLDEHRCREHVDRSGVLAAATITYLG 419 Sbjct: 384 443 Query: 420 YDNXXXXXXXXXXSGRPLEQLLVEGGWMTEKQIQEVLHP 458 Sbjct: 444 482 >PA0854 [C] COG0114 Fumarase Length = 464 Score = 278 bits (712), Expect = 1e-74, Method: Compositional matrix adjust. Identities = 176/459 (38%), Positives = 249/459 (54%), Gaps = 1/459 (0%) Query: 8 RMERDALGSLPVPQDAYYGIHTARAKENFAAGGRPANRKLMHAIARVKQAAAKVNGRNHA 67 R E D+LG++ VP DAY+G T R+ ENFA GG+ ++HA+A +K+AAA+VN Sbjct: 3 RTETDSLGTIEVPDDAYWGAQTQRSLENFAIGGQRMPLAVIHALALIKKAAARVNDHLGE 62 Query: 68 LPQQKVQAILAACEEILDGCLDAHLIVDAYQGGAGTSSNMNVNEVIANRAIELLGGSKGD 127 LP + + I A +E+L G D H + +Q G+GT +NMNVNEVIA RA EL G +G Sbjct: 63 LPPEVARLIEQAADEVLAGRHDEHFPLVVWQTGSGTQTNMNVNEVIAGRANELAGNPRGG 122 Query: 128 YSIVHPIDDVNLHQSTNDVYPTALRIAVIPLLR-QLAEELASLQEVFQVKEHEYADLLRL 186 S VHP D VN QS+ND +PTA+ IA + QL +A L + +A L++ Sbjct: 123 KSPVHPNDHVNRAQSSNDSFPTAMHIAAAKAVHEQLLPAIAELSGGLAEQSARHASLVKT 182 Query: 187 GRTQLMDALPILAGQSFGAYAKAAARDRWRLYKAEERLREINIGGTAVGTGMNAPLTYIY 246 GRT LMDA PI GQ A+ + A + ++ GGTAVGTG+NAP + Sbjct: 183 GRTHLMDATPITFGQELSAFVAQLDYAERAIRAALPAVYQLAQGGTAVGTGLNAPKGFAD 242 Query: 247 TIADELRELTGLGLCRSDFPMDGTQNMDVFVEVSGLLKAAAVNLLKISNDFRLLSSGPAG 306 IA E+ +GL + + V +SG LK+ AV L+KI+ND RLL SGP Sbjct: 243 AIAAEIAAESGLPFVAAPNKFAALAGHEPLVILSGALKSLAVALMKIANDLRLLGSGPRA 302 Query: 307 GIGEYILPAVQAGSSIMPGKVNPVIAEMLGSVAMRVIADDTAVTLAAASGQLELNAFTPV 366 G E LPA + GSSIMPGKVNP E L +A +V+ +D+ ++ AA+ G L+LN F PV Sbjct: 303 GFAEVKLPANEPGSSIMPGKVNPTQCEALSMLACQVMGNDSTISFAASQGHLQLNVFKPV 362 Query: 367 XXXXXXXXXXXXXHGIPLFRERCLSGLKLDEHRCREHVDRSGVLAAATITYLGYDNXXXX 426 G F + C++GL+ D R + ++R +L A ++GYD Sbjct: 363 IVYNLLESIRLLADGCRNFNKHCVAGLEPDAQRMADLLERGLMLVTALNPHIGYDKAAEI 422 Query: 427 XXXXXXSGRPLEQLLVEGGWMTEKQIQEVLHPLEVTKPG 465 G L ++ G++ E Q E + P ++ + G Sbjct: 423 AKKAYAEGTTLRAAALQLGYLDEAQFDEWVRPEQMLEAG 461 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.318 0.135 0.389 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 35,045,104 Number of extensions: 1394897 Number of successful extensions: 3524 Number of sequences better than 1.0e-05: 16 Number of HSP's gapped: 3503 Number of HSP's successfully gapped: 16 Length of query: 484 Length of database: 38,378,431 Length adjustment: 110 Effective length of query: 374 Effective length of database: 25,691,691 Effective search space: 9608692434 Effective search space used: 9608692434 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 118 (50.1 bits)