BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0504.0009.p (260 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value alr2467 [S] COG1434 Uncharacterized conserved protein 96 4e-20 mll0674 [S] COG1434 Uncharacterized conserved protein 95 1e-19 BMEI0810 [S] COG1434 Uncharacterized conserved protein 83 5e-16 STM0990 [S] COG1434 Uncharacterized conserved protein 80 3e-15 BS_ycbC [EM] COG0329 Dihydrodipicolinate synthase/N-acetylneuram... 77 2e-14 >alr2467 [S] COG1434 Uncharacterized conserved protein Length = 359 Score = 96.3 bits (238), Expect = 4e-20, Method: Compositional matrix adjust. Identities = 14/269 (5%), Positives = 32/269 (11%), Gaps = 37/269 (13%) Query: 5 IYFIKFVYSFVLPPGLFVILLLGLTVWLWRXXXXVWLWRRSRRPAXXXXXXXXXXXXSMT 64 + + + L + Sbjct: 3 AATVVINRRALRHNLQRLR---ELAPAS------KMVAVVKANAYGHGLLETARTLPDAD 53 Query: 65 PWISNLLMGGLERQ-YDKPELLQGDVIVVLGGGASSG-----TPDIDGEGNLFGSAANRL 118 + L L + + + + + E Sbjct: 54 AFGVARLEEALRLRAGGITKPVLLLEGFFDARDLPTISAQHFHTAVHNEEQ-------LA 106 Query: 119 LTAVRLYRQTGLP-ILFSGGQVF---PDSGNEADIAKRQLIGLGVPERDILAENRSLNTE 174 + + G EA + V + + + + E Sbjct: 107 ALEEASLDEPVTVWMKLDTGMHRLGVRPEQAEAFYHR-LTQCKNVRQPVNIVSHFARADE 165 Query: 175 QNAANTAAMMNSKGLSHPILVTSAFHMPRAMAFFKDNGLAPLAYPTDYTDSRGSGLYPAM 234 T + P L Sbjct: 166 PKCGATEKQLAIFNTFCEGKPGQRSIAASGGILLWPQSHFDWVRPGIILYGVSP-LEDRS 224 Query: 235 FTPSPGAMN---NT------GTALKEYLG 254 G T Sbjct: 225 TGADFGCQPVMSLTSSLIAVREHKAGEPV 253 >mll0674 [S] COG1434 Uncharacterized conserved protein Length = 265 Score = 94.7 bits (234), Expect = 1e-19, Method: Compositional matrix adjust. Identities = 72/204 (35%), Positives = 109/204 (53%), Gaps = 12/204 (5%) Query: 62 SMTPWIS--NLLMGGLERQYDKPELLQG-DVIVVLGGGASSGTPDIDGEGNLFGSAANRL 118 +++ W S +++ LE ++ +P L Q D IVVLGGG G ++ G S+ +R+ Sbjct: 50 ALSTWTSLGAMMLNPLEERFPRPPLPQKVDGIVVLGGGFE-GAINLARGGYELSSSGDRM 108 Query: 119 LTAVRLYRQTGL-PILFSGGQ--VFPDSGNEADIAKRQLIGLGVPERDILAENRSLNTEQ 175 + L R+ L ++ SGG F D+ +AD A R L+ LGV ++ E++S NT + Sbjct: 109 VETAILARRFPLAKVVVSGGHGAFFIDAEGDADSASRMLVPLGVSADRLVLEDKSRNTYE 168 Query: 176 NAANTAAMMNSKGLSHPILVTSAFHMPRAMAFFKDNGLAPLAYPTDYTDS--RGSGLYPA 233 NA + ++ K +LVTSAFHMPRA A F G + +P DY S G GL+ Sbjct: 169 NAIFSRKLVEPKPGETWLLVTSAFHMPRAKALFDKAGFPTVPWPVDYHTSGKEGVGLFRD 228 Query: 234 MFTPSPGAMNNTGTALKEYLGLLA 257 S + NT AL+E++GL A Sbjct: 229 NAIDS---VQNTTIALREWIGLFA 249 >BMEI0810 [S] COG1434 Uncharacterized conserved protein Length = 264 Score = 82.8 bits (203), Expect = 5e-16, Method: Compositional matrix adjust. Identities = 71/197 (36%), Positives = 102/197 (51%), Gaps = 15/197 (7%) Query: 70 LLMGGLERQYDKPELL--QGDVIVVLGGGASSGTPDIDGEGNL-FGSAANRLLTAVRLYR 126 +L+ LE ++ K E L D I+VLGG + + G N SAA+R++ +RL R Sbjct: 60 MLLSPLENRFPKSESLPQHVDGIIVLGGYMNGEI--VAGRQNFELNSAADRIVETMRLAR 117 Query: 127 -QTGLPILFSGGQ--VFPDSGNEADIAKRQLIGLGVPERDILAENRSLNTEQNAANTAAM 183 IL SGG+ F S EA+ + L+ LG + E +S NT +NA + A+ Sbjct: 118 LYPDAKILVSGGEGTFFEKSAREAETTRALLLDLGFSGNRYIFEGKSRNTVENAIFSQAL 177 Query: 184 MNSKGLSHPILVTSAFHMPRAMAFFKDNGLAPLAYPTDY-TDSRGS-GLYPAMFTPSPG- 240 K +LVTSA+HMPRA+ F+ G A+P DY T +R + GLY SP Sbjct: 178 AQPKPGETWLLVTSAYHMPRAVGCFRKAGFDVTAWPVDYKTRTRETFGLY----LESPND 233 Query: 241 AMNNTGTALKEYLGLLA 257 A++ AL+E+ GL A Sbjct: 234 ALSRFSMALREWTGLAA 250 >STM0990 [S] COG1434 Uncharacterized conserved protein Length = 258 Score = 80.5 bits (197), Expect = 3e-15, Method: Compositional matrix adjust. Identities = 66/193 (34%), Positives = 102/193 (52%), Gaps = 8/193 (4%) Query: 67 ISNLLMGGLERQYDKPELLQG-DVIVVLGGGASSGTPDIDGEGNLFGSAANRLLTAVRLY 125 +S+ L+ +E +Y + Q + IVVLGGG + P NL ++ RL +RL+ Sbjct: 58 VSDHLLRPIENRYPTWQGPQKVEYIVVLGGG-YTWNPQWAPSSNLINNSLPRLAEGIRLW 116 Query: 126 RQT-GLPILFSGGQVFPDSGNEADIAKRQLIGLGVPERDILAENRSLNTEQNAANTAAMM 184 R G ++F+GG ++ + A++ R LGVP DI+ ++ +TE+ AA A+ Sbjct: 117 RANPGARLIFTGGVAKTNTVSTAEVGARVAQSLGVPRSDIITLDKPKDTEEEAA---AVK 173 Query: 185 NSKGLSHPILVTSAFHMPRAMAFFKDNGLAPLAYPTDYTDSRGSGLYP-AMFTPSPGAMN 243 + G + +LVTSA H+PRAM FF+ GL PL P + + S L P PSP + Sbjct: 174 QAIGDAPFLLVTSASHLPRAMIFFQHAGLNPLPAPANQL-AIDSPLNPWERAIPSPVWLM 232 Query: 244 NTGTALKEYLGLL 256 ++ A E LG L Sbjct: 233 HSDRAGYETLGRL 245 >BS_ycbC [EM] COG0329 Dihydrodipicolinate synthase/N-acetylneuraminate lyase Length = 259 Score = 77.4 bits (189), Expect = 2e-14, Method: Compositional matrix adjust. Identities = 50/135 (37%), Positives = 75/135 (55%), Gaps = 5/135 (3%) Query: 88 DVIVVLGGGASSGTPDIDGEGNLFGSAANRLLTAVRLYRQT-GLPILFSGGQVFPDSGNE 146 D IVVLGGG + P NL ++ RL +RL+R+ G ++F+GG ++ + Sbjct: 80 DYIVVLGGGYT-WNPQWAPSSNLINNSLPRLNEGIRLWRENPGSKLIFTGGVAKTNTVST 138 Query: 147 ADIAKRQLIGLGVPERDILAENRSLNTEQNAANTAAMMNSKGLSHPILVTSAFHMPRAMA 206 A++ R LGVP I+ + +TE+ AA A+ + G + +LVTSA H+PRAM Sbjct: 139 AEVGARVAQSLGVPREQIITLDLPKDTEEEAA---AVKQAIGDAPFLLVTSASHLPRAMI 195 Query: 207 FFKDNGLAPLAYPTD 221 FF+ GL PL P + Sbjct: 196 FFQQEGLNPLPAPAN 210 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.321 0.139 0.426 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 19,721,998 Number of extensions: 822945 Number of successful extensions: 1980 Number of sequences better than 1.0e-05: 15 Number of HSP's gapped: 1970 Number of HSP's successfully gapped: 15 Length of query: 260 Length of database: 38,378,431 Length adjustment: 104 Effective length of query: 156 Effective length of database: 26,383,695 Effective search space: 4115856420 Effective search space used: 4115856420 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.9 bits) S2: 115 (48.9 bits)