BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0504.0007.p (317 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value MA0853 [V] COG1131 ABC-type multidrug transport system, ATPase c... 317 2e-86 BH0818 [V] COG1131 ABC-type multidrug transport system, ATPase c... 189 4e-48 AF1136 [V] COG1131 ABC-type multidrug transport system, ATPase c... 176 5e-44 lin0750 [V] COG1131 ABC-type multidrug transport system, ATPase ... 171 1e-42 CC3280 [V] COG1131 ABC-type multidrug transport system, ATPase c... 168 1e-41 >MA0853 [V] COG1131 ABC-type multidrug transport system, ATPase component Length = 314 Score = 317 bits (812), Expect = 2e-86, Method: Compositional matrix adjust. Identities = 162/297 (54%), Positives = 214/297 (72%), Gaps = 1/297 (0%) Query: 14 AIQIDGVHKKFGDYTVLNNLSLEVSRGEIFGFLGLNGAGKTTTIKMLLSMIKPTSGKLYM 73 I+ D + K FGD +N++SL V +GEI+GFLGL+GAGKTTTI+MLL MIKPTSG Y+ Sbjct: 11 VIKTDRLSKDFGDLHAVNSISLCVGKGEIYGFLGLSGAGKTTTIRMLLGMIKPTSGAAYL 70 Query: 74 LGEKVDAGNSKLWSKVGYLEEATF-YPDLTVTENLDIARRMQGLPDKDAVHQVIYKLGLE 132 G+ V+AG ++LW VGYL E + YPDLTV E L+I RR++G+ D +A+ V+ KL L Sbjct: 71 NGKLVNAGETELWKNVGYLVELPYSYPDLTVKEKLEIIRRLRGIDDTNAISAVMGKLQLN 130 Query: 133 PHKKKKAKHLSLGNKQRLGLAKAMIHNPEILILDEPINGLDPAGVAEIRNMLYNLANNFG 192 + +KA LS GN+QRLG+AKA+IH+PEILILDEP NGLDPAG+ EIR +L +LA N G Sbjct: 131 KYADRKAGKLSQGNRQRLGIAKALIHSPEILILDEPSNGLDPAGIVEIRELLLDLALNKG 190 Query: 193 ITVFISSHLLEELSKVSTRIGIIHSGQLVKEVAMDKLEQSLEKSLVVNGRNKPALKKVLE 252 +TVFISSH+L E+SK+++RIGIIH G L++E+ D+LEQ K LVVN + K +L Sbjct: 191 VTVFISSHILSEVSKIASRIGIIHEGVLIQEINADRLEQLRLKKLVVNTVDNEKAKTILF 250 Query: 253 EHGYAFEDTPDGSIKLTNEHAADHPERLAELLVQSNQPPTSLRVITEDLEGYFLRTI 309 GY +PD ++ +T+E PE++AE+LV S PP L V EDLE YFLR+I Sbjct: 251 AGGYDAVLSPDRNLIITDERVIGQPEKIAEILVYSGCPPVLLMVEEEDLESYFLRSI 307 >BH0818 [V] COG1131 ABC-type multidrug transport system, ATPase component Length = 314 Score = 189 bits (481), Expect = 4e-48, Method: Compositional matrix adjust. Identities = 106/301 (35%), Positives = 177/301 (58%), Gaps = 5/301 (1%) Query: 12 TPAIQIDGVHKKFGDYTVLNNLSLEVSRGEIFGFLGLNGAGKTTTIKMLLSMIKPTSGKL 71 T I + K F +++NL+L V++GEI+GFLG NGAGKTT +KML++ +KP++G++ Sbjct: 2 TKVITTRNLTKTFQGKEIISNLNLHVNKGEIYGFLGPNGAGKTTVMKMLMNFVKPSAGEI 61 Query: 72 YMLGEKVDAGNSKLWSKVG-YLEEATFYPDLTVTENLDIARRMQGLPDKDAVHQVIYKLG 130 + G+++ + + ++ ++G +E FY L+ ENL++ G A+ + + + Sbjct: 62 ELFGQRLTSQSYEMLKRIGSMIEFPIFYEKLSARENLELHCEYMGYYKPSAIEEALEMVK 121 Query: 131 LEPHKKKKAKHLSLGNKQRLGLAKAMIHNPEILILDEPINGLDPAGVAEIRNMLYNLANN 190 L+ K K SLG KQRLG+A+A+ PE+LILDEPINGLDP G+ EIR + L N Sbjct: 122 LQLTGSKAVKDFSLGMKQRLGIARAICTKPELLILDEPINGLDPVGIKEIRQLFQTLCNE 181 Query: 191 FGITVFISSHLLEELSKVSTRIGIIHSGQLVKEVAMDKLE-QSLEKSLVVNGRNKPALKK 249 +G+T+ ISSH+L E+ +++ +G+I +G LV EVA+D + Q E ++ + AL Sbjct: 182 YGVTILISSHILSEIEQIADTVGVIRNGMLVAEVALDDIRSQQTEYIELLTYDARKALYV 241 Query: 250 VLEEHGYAFEDTPDGS-IKLTNEHAADHPERLAELLVQSNQPPTSLRVITEDLEGYFLRT 308 + E G D S I++ + H + +L++ L+ ++ ++ LE YF+ Sbjct: 242 LDNELGLKNVKLMDQSLIRIYDHHLTQN--QLSKTLISNDVNIEAIARKNHSLEDYFMNL 299 Query: 309 I 309 I Sbjct: 300 I 300 >AF1136 [V] COG1131 ABC-type multidrug transport system, ATPase component Length = 294 Score = 176 bits (445), Expect = 5e-44, Method: Compositional matrix adjust. Identities = 101/243 (41%), Positives = 145/243 (59%), Gaps = 3/243 (1%) Query: 15 IQIDGVHKKFGDYTVLNNLSLEVSRGEIFGFLGLNGAGKTTTIKMLLSMIKPTSGKLYML 74 I+++ + K F + L+ +SL V RGEIFGFLG NGAGKTTTI L +IKPTSG + + Sbjct: 4 IEVENLTKVFNGFRALDGISLVVERGEIFGFLGPNGAGKTTTINCCLGLIKPTSGSVRIA 63 Query: 75 GEKVDAGNSKLWSKVGYL-EEATFYPDLTVTENLDIARRMQGLPDKDAVHQVIYKLGLEP 133 G V+ ++ GYL E FYP+LT +NL P KD V +++ +GL+ Sbjct: 64 GMDVEEKPVEVKEICGYLPENYGFYPNLTARQNLLYFSEFYANP-KDNVDELLALVGLQD 122 Query: 134 HKKKKAKHLSLGNKQRLGLAKAMIHNPEILILDEPINGLDPAGVAEIRNMLYNLANNFGI 193 KK S G KQRL LA+A+I++PE++ LDEP NGLDP G+A+ R ++ L N G Sbjct: 123 SADKKVGEFSRGMKQRLALAQALINDPEVVFLDEPTNGLDPQGIADFRKIIREL-NQKGK 181 Query: 194 TVFISSHLLEELSKVSTRIGIIHSGQLVKEVAMDKLEQSLEKSLVVNGRNKPALKKVLEE 253 T F SSH+L E+ +V + +GII+ G++VK + +L S+E + R +L + E Sbjct: 182 TFFFSSHILSEVREVCSVVGIINRGRIVKVGKISELSGSMEVVVQTEPRADESLLREFGE 241 Query: 254 HGY 256 Y Sbjct: 242 VEY 244 >lin0750 [V] COG1131 ABC-type multidrug transport system, ATPase component Length = 301 Score = 171 bits (433), Expect = 1e-42, Method: Compositional matrix adjust. Identities = 88/210 (41%), Positives = 133/210 (63%), Gaps = 1/210 (0%) Query: 14 AIQIDGVHKKFGDYTVLNNLSLEVSRGEIFGFLGLNGAGKTTTIKMLLSMIKPTSGKLYM 73 A+Q+ +HKK ++ +S EV GE+FGFLG NGAGKTTTI+M++ +IKPTSG + + Sbjct: 5 ALQVTNLHKKIRKREIIKGISFEVRPGEVFGFLGPNGAGKTTTIRMIVGLIKPTSGTILI 64 Query: 74 LGEKVDAGNSKLWSKVGYL-EEATFYPDLTVTENLDIARRMQGLPDKDAVHQVIYKLGLE 132 G+ + ++ +G + E FY LT ENL RM K+ + +V +GLE Sbjct: 65 GGKDIRKNFTEAMRGLGSIVENPEFYTFLTGQENLAYFARMDPSIKKERIQEVTELVGLE 124 Query: 133 PHKKKKAKHLSLGNKQRLGLAKAMIHNPEILILDEPINGLDPAGVAEIRNMLYNLANNFG 192 + SLG +QRLG+A+A++ +P++LILDEP NGLDP+G+ E+R+ + LA N G Sbjct: 125 KRINDRVSTYSLGMRQRLGIAQALLSSPKLLILDEPTNGLDPSGIHEMRDFIRALARNEG 184 Query: 193 ITVFISSHLLEELSKVSTRIGIIHSGQLVK 222 I+V +SSHLL E+ + R+ I+ G ++K Sbjct: 185 ISVLVSSHLLSEIELLCDRVAIMTDGTIIK 214 >CC3280 [V] COG1131 ABC-type multidrug transport system, ATPase component Length = 311 Score = 168 bits (425), Expect = 1e-41, Method: Compositional matrix adjust. Identities = 103/286 (36%), Positives = 160/286 (55%), Gaps = 12/286 (4%) Query: 12 TPAIQIDGVHKKFGDYTVLNNLSLEVSRGEIFGFLGLNGAGKTTTIKMLLSMIKPTSGKL 71 + AI+ G+ ++FG +++LS+ V ++GFLG NGAGKTTT+KM+L +I+P+ G Sbjct: 2 SAAIETQGLSRRFGQRRAVDDLSMTVPERAVYGFLGRNGAGKTTTLKMILGLIRPSVGTA 61 Query: 72 YMLGEKVDAGNSKLWSKVGYLEEA-TFYPDLTVTENLDIARRMQGLPDKDAVHQVIYKLG 130 + G V +VG L EA FY +LT ENL + + GL + + + +V+ + Sbjct: 62 RVNGIDVSRDRIGAARQVGALLEAHGFYGNLTGRENLGLTATLIGLRNSE-IDRVLDVVE 120 Query: 131 LEPHKKKKAKHLSLGNKQRLGLAKAMIHNPEILILDEPINGLDPAGVAEIRNMLYNLANN 190 + +K SLG +QRLGLA+AM+ P IL+LDEP NGLDP G+A++R L +L Sbjct: 121 MRADADRKVGGYSLGMRQRLGLARAMLGAPPILVLDEPTNGLDPDGIADMRRFLRSLPER 180 Query: 191 FGITVFISSHLLEELSKVSTRIGIIHSGQLVKEVAMDKLEQSLEKSLVVNGRNKPALKKV 250 G TV +SSHLL E+ + +T +G+++ G+LV E + +L+ L +++ + + Sbjct: 181 TGATVLLSSHLLGEIEQTATHVGVVNDGRLVLEGELSRLKADLAPEILLRTGDDARAVQA 240 Query: 251 LEEHGY---AFEDTPDGSIKLTNEHAADHPERLAEL---LVQSNQP 290 L GY AFE G + + D + AEL LV P Sbjct: 241 LLAGGYSPVAFE----GGLSVALRPGQDLDQAAAELVRVLVAGGAP 282 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.316 0.136 0.379 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 24,127,266 Number of extensions: 1040429 Number of successful extensions: 9826 Number of sequences better than 1.0e-05: 2126 Number of HSP's gapped: 7338 Number of HSP's successfully gapped: 2366 Length of query: 317 Length of database: 38,378,431 Length adjustment: 106 Effective length of query: 211 Effective length of database: 26,153,027 Effective search space: 5518288697 Effective search space used: 5518288697 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.6 bits) S2: 116 (49.3 bits)