BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0504.0004.p (300 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value CAC0564 [TK] COG0745 Response regulators consisting of a CheY-li... 181 1e-45 CAC0321 [TK] COG0745 Response regulators consisting of a CheY-li... 178 9e-45 ML0125 [GC] COG1819 Glycosyl transferases, related to UDP-glucur... 170 3e-42 L0125 [TK] COG0745 Response regulators consisting of a CheY-like... 170 3e-42 SP2082 [TK] COG0745 Response regulators consisting of a CheY-lik... 168 9e-42 >CAC0564 [TK] COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Length = 233 Score = 181 bits (459), Expect = 1e-45, Method: Compositional matrix adjust. Identities = 98/229 (42%), Positives = 146/229 (63%), Gaps = 10/229 (4%) Query: 72 KTILVVDDDEEIVKLITKSLRYEQFAVITASSGREALSAVDDHHIDFIVLDIVMPDMNGL 131 +T+LVVDD++EI LI L E F VI A +G EAL + D + ++LDI+MP M+G+ Sbjct: 4 RTVLVVDDEKEIRDLIGIYLNNEGFNVIKAENGVEALEILKDTEVQLVLLDIMMPKMDGI 63 Query: 132 DVCRTIRSSYNVPILLLSARDQDIDKIVGLEIGADDYMTKPFSIQELASRIKAHFRKVDR 191 C IR N PI++LSA+ +D+DKI+GL GADDY++KPF+ EL +R+K+ R+ + Sbjct: 64 TTCMKIREDKNTPIIMLSAKGEDMDKILGLTTGADDYISKPFNPLELIARVKSQIRRYTK 123 Query: 192 LHKEWGELSPAKEKADAPLILNDKTFEAFLYSRKLDLSAKEFQILSILMRHPNQVLSREQ 251 L+ + S E + + +N T E + R + L+ +EF IL +L R+ V S E+ Sbjct: 124 LNSTYESNSANIEVGE--ITINTDTHEVKIGDRTVSLTKREFDILVLLSRNKGVVFSTEK 181 Query: 252 IYENVWGDEYGEI-NTVTVHIKNIRKKL-----GPEHNFIKTIWGIGYK 294 IYE+VW +E+ + NTV VHI+ IR+K+ PE +IKT+WG+GYK Sbjct: 182 IYESVWHEEFYDCHNTVMVHIRKIREKIEKNPRKPE--YIKTVWGVGYK 228 >CAC0321 [TK] COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Length = 230 Score = 178 bits (451), Expect = 9e-45, Method: Compositional matrix adjust. Identities = 91/235 (38%), Positives = 149/235 (63%), Gaps = 19/235 (8%) Query: 72 KTILVVDDDEEIVKLITKSLRYEQFAVITASSGREALSAVDDHHIDFIVLDIVMPDMNGL 131 K IL+++D+ I +L L F V SG+ L A + + + I+LD+++P+++G Sbjct: 2 KKILIIEDETSIAELEKDYLELSNFKVDIEVSGKTGLEAAKEKNYELIILDLMLPEIDGF 61 Query: 132 DVCRTIRSSYNVPILLLSARDQDIDKIVGLEIGADDYMTKPFSIQELASRIKAHFRKVDR 191 ++C+ IR N PIL++SA+ +DIDKI GL +GADDYMTKPFS EL +R+KAH + +R Sbjct: 62 EICKQIRKIKNTPILMVSAKKEDIDKIRGLGLGADDYMTKPFSPSELVARVKAHISRYER 121 Query: 192 LHKEWGELSPAKEKADAP-----LILNDKTFEAFLYSRKLDLSAKEFQILSILMRHPNQV 246 L ++ + + D L +N + + F+ ++ +AKEF +L L ++P++V Sbjct: 122 L------VNSSNKNLDDEIEIRGLNINKASRKVFVNGKESQFTAKEFDLLVFLAQNPDRV 175 Query: 247 LSREQIYENVWG-DEYGEINTVTVHIKNIRKKL-----GPEHNFIKTIWGIGYKY 295 S+E++++ +WG D +GEI TVTVHIK IR+K+ PE +I+T+WG GY++ Sbjct: 176 FSKEELFDKIWGMDSFGEIATVTVHIKKIREKIEKDTSNPE--YIETVWGAGYRF 228 >ML0125 [GC] COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase Length = 233 Score = 170 bits (430), Expect = 3e-42, Method: Compositional matrix adjust. Identities = 91/226 (40%), Positives = 147/226 (65%), Gaps = 5/226 (2%) Query: 72 KTILVVDDDEEIVKLITKSLRYEQFAVITASSGREALSAVDDHHIDFIVLDIVMPDMNGL 131 K ILVVDD++ I ++ +L E F V TA G EAL A + D I+LD+++P ++GL Sbjct: 2 KKILVVDDEKPISDIVKFNLTKEGFEVFTAFDGEEALEAFKEVQPDLILLDLMLPKLDGL 61 Query: 132 DVCRTIRSSYNVPILLLSARDQDIDKIVGLEIGADDYMTKPFSIQELASRIKAHFRKVDR 191 DV R IR + + PI+++SA+D + DK++GLE+GADDY+TKPFS +EL +RIKA+ R+++ Sbjct: 62 DVAREIRKTSDTPIIMVSAKDSEFDKVIGLELGADDYVTKPFSNRELLARIKANLRRINV 121 Query: 192 LHKEWGELSPAKEKADAPLILNDKTFEAFLYSRKLDLSAKEFQILSILMRHPNQVLSREQ 251 E + + KE L +N + A+ ++LDL+ +EF++L L +H +V++RE Sbjct: 122 APAESTD-NVKKELIIGNLRINPAHYAAYKNDKQLDLTHREFELLYYLAQHLGEVITREN 180 Query: 252 IYENVWG-DEYGEINTVTVHIKNIRKKL--GPEH-NFIKTIWGIGY 293 + E VWG D +G++ TV V ++ +R+K+ P ++ T G+GY Sbjct: 181 LLETVWGYDYFGDVRTVDVTVRRLREKVEDTPSRPQYVSTRRGVGY 226 >L0125 [TK] COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Length = 233 Score = 170 bits (430), Expect = 3e-42, Method: Compositional matrix adjust. Identities = 91/226 (40%), Positives = 147/226 (65%), Gaps = 5/226 (2%) Query: 72 KTILVVDDDEEIVKLITKSLRYEQFAVITASSGREALSAVDDHHIDFIVLDIVMPDMNGL 131 K ILVVDD++ I ++ +L E F V TA G EAL A + D I+LD+++P ++GL Sbjct: 2 KKILVVDDEKPISDIVKFNLTKEGFEVFTAFDGEEALEAFKEVQPDLILLDLMLPKLDGL 61 Query: 132 DVCRTIRSSYNVPILLLSARDQDIDKIVGLEIGADDYMTKPFSIQELASRIKAHFRKVDR 191 DV R IR + + PI+++SA+D + DK++GLE+GADDY+TKPFS +EL +RIKA+ R+++ Sbjct: 62 DVAREIRKTSDTPIIMVSAKDSEFDKVIGLELGADDYVTKPFSNRELLARIKANLRRINV 121 Query: 192 LHKEWGELSPAKEKADAPLILNDKTFEAFLYSRKLDLSAKEFQILSILMRHPNQVLSREQ 251 E + + KE L +N + A+ ++LDL+ +EF++L L +H +V++RE Sbjct: 122 APAESTD-NVKKELIIGNLRINPAHYAAYKNDKQLDLTHREFELLYYLAQHLGEVITREN 180 Query: 252 IYENVWG-DEYGEINTVTVHIKNIRKKL--GPEH-NFIKTIWGIGY 293 + E VWG D +G++ TV V ++ +R+K+ P ++ T G+GY Sbjct: 181 LLETVWGYDYFGDVRTVDVTVRRLREKVEDTPSRPQYVSTRRGVGY 226 >SP2082 [TK] COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Length = 235 Score = 168 bits (426), Expect = 9e-42, Method: Compositional matrix adjust. Identities = 93/238 (39%), Positives = 149/238 (62%), Gaps = 14/238 (5%) Query: 70 MPKTILVVDDDEEIVKLITKSLRYEQFAVITASSGREALSAVDDHHIDFIVLDIVMPDMN 129 M K +L+VDD+E I+KL+ L E F+ ++GR+AL+ + DFI+LDI++P ++ Sbjct: 1 MTKQVLLVDDEEHILKLLDYHLSKEGFSTQLVTNGRKALALAETEPFDFILLDIMLPQLD 60 Query: 130 GLDVCRTIRS-SYNVPILLLSARDQDIDKIVGLEIGADDYMTKPFSIQELASRIKAHFRK 188 G++VC+ +R+ PI+++SA+ + DK++ LE+GADDY+TKPFS +EL +R+KA R+ Sbjct: 61 GMEVCKRLRAKGVKTPIMMVSAKSDEFDKVLALELGADDYLTKPFSPRELLARVKAVLRR 120 Query: 189 VDRLHKEWGELSPAKEKAD-----APLILNDKTFEAFLYSRKLDLSAKEFQILSILMRHP 243 K E + AD L + + E + ++ L L+ KEF++L LM+HP Sbjct: 121 T----KGEQEGDDSDNIADDSWLFGTLKVYPERHEVYKANKLLSLTPKEFELLLYLMKHP 176 Query: 244 NQVLSREQIYENVWGDEYG-EINTVTVHIKNIRKKL--GPEH-NFIKTIWGIGYKYTE 297 N L+RE++ E +WG ++G E V VHI +R+K+ P+ FI+TI G GYK+ E Sbjct: 177 NMTLTRERLLERIWGYDFGQETRLVDVHIGKLREKIEDNPKAPQFIRTIRGYGYKFKE 234 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.322 0.138 0.412 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 21,452,925 Number of extensions: 847796 Number of successful extensions: 2995 Number of sequences better than 1.0e-05: 497 Number of HSP's gapped: 2484 Number of HSP's successfully gapped: 499 Length of query: 300 Length of database: 38,378,431 Length adjustment: 106 Effective length of query: 194 Effective length of database: 26,153,027 Effective search space: 5073687238 Effective search space used: 5073687238 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.9 bits) S2: 115 (48.9 bits)