BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0500.0014.p (166 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value DR2362 [T] COG0664 cAMP-binding proteins - catabolite gene activ... 62 4e-10 CAP0082 [T] COG0664 cAMP-binding proteins - catabolite gene acti... 54 1e-07 BMEII0986 [T] COG0664 cAMP-binding proteins - catabolite gene ac... 51 9e-07 CC2171_1 [T] COG0664 cAMP-binding proteins - catabolite gene act... 51 1e-06 SPy1548 [T] COG0664 cAMP-binding proteins - catabolite gene acti... 50 1e-06 >DR2362 [T] COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Length = 297 Score = 62.0 bits (149), Expect = 4e-10, Method: Compositional matrix adjust. Identities = 9/160 (5%), Positives = 27/160 (16%), Gaps = 7/160 (4%) Query: 6 GEVLFRQGDACQNLFQVKSGLFKVIRLHENGNMVLFNLLYPGETVPHHSLISPKEAHGT- 64 V + + + V+ + + F+ + T +S Sbjct: 39 SVVSEPGFNIRVRKNESNNSHEIVLTVASLEYIWAFSNFFWVFTQ-EYSKSQKNNDEHFD 97 Query: 65 AVAMMKSEVELVPAAEWYRELREDPDKVMEIALLLQEKVRFMQTRLDHLTVGTPGERL-D 123 + + + L+ + E + Sbjct: 98 LTGKNRLKKSDELLKWARKNLQTTGCESWPKKCPKPEAYLQGSEDSQVASEIFLCAIAWI 157 Query: 124 LLKRWLLEY----SHGAELTDLLTQEEIGQLIGVRRETVN 159 L + +E + Sbjct: 158 LHHEISHVVLQHPLVTTAFSTQEEREADSHATKWILGNLY 197 >CAP0082 [T] COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Length = 188 Score = 53.5 bits (127), Expect = 1e-07, Method: Compositional matrix adjust. Identities = 37/161 (22%), Positives = 73/161 (45%), Gaps = 3/161 (1%) Query: 2 ILHKGEVLFRQGDACQNLFQVKSGLFKVIRLHENGNMVLFNLLYPGETVPHHSLISPKEA 61 + ++++RQG+ +N + +K G +V +G + + GE S Sbjct: 1 MFKDNQIIYRQGEIAKNFYYLKEGRVQVFVNSTDGLEKILAIYKKGEIFGEASFFDGFPR 60 Query: 62 HGTAVAMMKSEVELVPAAEWYRELREDPDKVMEIALLLQEKVRFMQTRLDHLTVGTPGER 121 +A SE+ + ++ +++P + LL +KVR + +D ++ P E+ Sbjct: 61 MSSAKTFSDSEIININKSDIMLYFQKEPLLALNFIELLSKKVRMLSNEIDSISF-LPAEK 119 Query: 122 LDLLKRWLLEYSHGAELTDLLTQEEIGQLIGVRRETVNRLL 162 + ++LL S + T E+IG+ +GV R TV+R L Sbjct: 120 --RIAQYLLNVSLSNNCSINCTHEDIGKAVGVSRVTVSRTL 158 >BMEII0986 [T] COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Length = 231 Score = 50.8 bits (120), Expect = 9e-07, Method: Compositional matrix adjust. Identities = 36/165 (21%), Positives = 76/165 (46%), Gaps = 5/165 (3%) Query: 5 KGEVLFRQGDACQNLFQVKSGLFKVIRLHENGNMVLFNLLYPGETVPHHSLISPKEAHGT 64 +GE +F QGD + + G KV ++ +G ++ +++PG+ + + GT Sbjct: 37 QGESIFEQGDEASCFYLLLHGRLKVNQVTPDGQQIIVRMVHPGDLFGFARALQRNDYPGT 96 Query: 65 AVAMMKSEVELVPAAEWYRELREDPDKVMEIALLLQEKVRFMQTRLDHLTVGTPGER--- 121 A A+M+S V P W + ++P M + +++ TR+ ++ R Sbjct: 97 ATAVMESIVLAWPTELWDYFVEQNPGLAMNAIQTIGKRLEEAHTRIREMSTEEVERRVAH 156 Query: 122 --LDLLKRWLLEYSHGAELTDLLTQEEIGQLIGVRRETVNRLLRN 164 L L ++ + G + +++++I ++ G TV+R+L N Sbjct: 157 AVLRLSRQAGKKEETGIRIDFPISRQDIAEMTGTTLHTVSRILSN 201 >CC2171_1 [T] COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Length = 159 Score = 50.8 bits (120), Expect = 1e-06, Method: Compositional matrix adjust. Identities = 30/114 (26%), Positives = 52/114 (45%), Gaps = 3/114 (2%) Query: 3 LHKGEVLFRQGDACQNLFQVKSGLFKVIRLHENGNMVLFNLLYPGETVPHHSLISPKEAH 62 L G LF G+A +L+ +K+G R E ++ PGE +L+ Sbjct: 48 LPGGATLFEAGEAANHLYFLKTGRLGAFRREEGQEPQFLGVIRPGEPAGEMALVGGTAHS 107 Query: 63 GTAVAMMKSEVELVPAAEWYRELREDPDKVMEIALLLQEKVRFMQTRLDHLTVG 116 V++ SEV +P +++ EDP ++E++ L+ + R QT H +G Sbjct: 108 ANMVSLRDSEVLALPRDDFFEAAEEDPTVMIELSRLMIRRTRQAQT---HAAIG 158 >SPy1548 [T] COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Length = 226 Score = 50.1 bits (118), Expect = 1e-06, Method: Compositional matrix adjust. Identities = 41/162 (25%), Positives = 73/162 (45%), Gaps = 2/162 (1%) Query: 5 KGEVLFRQGDACQNLFQVKSGLFKVIRLHENGNMVLFNLLYPGETVPHHSLISPKEAHGT 64 K +LF +GD LF V SG FKV + ++G + + + G P+ L + H + Sbjct: 38 KDHILFFEGDKRDKLFLVTSGYFKVEQSDQSGTFMYTDFIRHGTIFPYGGLFTDDYYHFS 97 Query: 65 AVAMMKSEVELVPAAEWYRELREDPDKVMEIALLLQEKVRFMQTRLDHLTVGTPGER-LD 123 VAM P + E+ ++ + + + + + R+ +L + R + Sbjct: 98 VVAMTDVTYFYFPVDLFEDYSLENRLQMKHLYSKMSKLLELHELRVRNLITSSASSRVIQ 157 Query: 124 LLKRWLLEYSHGAE-LTDLLTQEEIGQLIGVRRETVNRLLRN 164 L L+E ++ L LT +I Q+ G RETV+ +LR+ Sbjct: 158 SLAILLVEMGKDSDTLPFQLTTTDIAQISGTTRETVSHVLRD 199 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.321 0.139 0.407 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 12,451,358 Number of extensions: 514238 Number of successful extensions: 1747 Number of sequences better than 1.0e-05: 15 Number of HSP's gapped: 1754 Number of HSP's successfully gapped: 15 Length of query: 166 Length of database: 38,378,431 Length adjustment: 98 Effective length of query: 68 Effective length of database: 27,075,699 Effective search space: 1841147532 Effective search space used: 1841147532 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 112 (47.8 bits)