BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0500.0011.p (461 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value STM4012 [H] COG0635 Coproporphyrinogen III oxidase and related F... 259 5e-69 CT746 [H] COG0635 Coproporphyrinogen III oxidase and related Fe-... 132 1e-30 CPn0380 [H] COG0635 Coproporphyrinogen III oxidase and related F... 124 3e-28 PA0386 [H] COG0635 Coproporphyrinogen III oxidase and related Fe... 123 5e-28 YPO0021 [H] COG0635 Coproporphyrinogen III oxidase and related F... 123 6e-28 >STM4012 [H] COG0635 Coproporphyrinogen III oxidase and related Fe-S oxidoreductases Length = 228 Score = 259 bits (663), Expect = 5e-69, Method: Compositional matrix adjust. Identities = 0/427 (0%), Positives = 0/427 (0%), Gaps = 20/427 (4%) Query: 33 DPYRNYLYSYPHKTAYRDLNPPVPLEPLWREEPAESFFLYMHIPFCGARCGFCNLFTLPD 92 N + Y + + + + T Sbjct: 5 GRSNNQVRPVTLTRNYTKHAE-GSVLVEFGDTKVLCTASIEEGVPRFLKGQGQGWITAEY 63 Query: 93 KRAEVHTVYVDALERQARQWAAFTGGKPFARFAIGGGTPSLLAPAQLRRLFRIAEDIMGL 152 T +A E + R ++ A + D++ Sbjct: 64 GMLPRSTHTRNAREAAKGKQG--GRTMEIQRLIARALRAAVDLKALGEFTITLDCDVLQA 121 Query: 153 DPASASISVETSPETLTEDKLNILKEHTVDRVSMGIQSFVAAESAAIYRPQNPDEVYRAL 212 D + T D L L E+ + + A + D Y Sbjct: 122 D-GGTRTASITGACVALVDALQKLVENGKLKTNPMKGMVAAVSVGIVNGEAVCDLEYVED 180 Query: 213 ELLKLYDFPVLNLDLIYGLPGQTVDSWLYSLEQAVNHEPEEIFIYPLYTRDHTIVKPEDI 272 + V+ D T + ++ E+ + Sbjct: 181 SAAETDMNVVMTEDGRIIEVQGTAEGEPFTHEELLILLALARGESNPL---------- 230 Query: 273 RRQTDIRHECYRAAQQLLAEHGYTQYSMRRFARATAGTHKSIIDYSCQEEGMVGLGCGAR 332 Sbjct: 231 ---- 286 Query: 333 SYTRNVHYASRYGVSRKATESIIADYVAAERYDTADYGIVLSLEEQKRRYILKAVLHSEG 392 Sbjct: 287 346 Query: 393 LKLADYSGRFGSSLWRDHPXXXXXXXXXXXXXXXXXXXXXXXXXXYSDSIGDWFISGEI- 451 Sbjct: 347 406 Query: 452 -REQMER 457 Sbjct: 407 413 >CT746 [H] COG0635 Coproporphyrinogen III oxidase and related Fe-S oxidoreductases Length = 228 Score = 132 bits (332), Expect = 1e-30, Method: Compositional matrix adjust. Identities = 0/364 (0%), Positives = 0/364 (0%), Gaps = 29/364 (7%) Query: 57 LEPLWREEPAESFFLYMHIPFCGARCGFCNLFTLPDKRAEVHTVYVDALERQARQWAAFT 116 E L + + A Q Sbjct: 39 CTASIEEGVPRF--LKGQGQGWITAEYGMLPRSTHTRNAREAAKGKQGGRTMEIQRLIAR 96 Query: 117 GGK-PFARFAIGGGTPSLLAPAQLRRLFRIAEDIMGLDPASASISVETSPETLTEDKLNI 175 + A+G T +L I G A +++ E + Sbjct: 97 ALRAAVDLKALGEFTITLDCDVLQADGGTRTASITGACVAL-VDALQKLVENGKLKTNPM 155 Query: 176 LKEHTV--DRVSMGIQSFVAAESAAIYRPQNPDEVYRALELLKLYDFPVLNLDLIYGLPG 233 + G + + V + + Sbjct: 156 KGMVAAVSVGIVNGEAVCDLEYVEDSAAETDMNVVMTEDGRIIEVQGTAEGEPFTHEELL 215 Query: 234 QTVDSWLYSLEQAVNHEPEEIFIY-----PLYTRDHTIVKPEDIRRQTDIRHECYRAAQQ 288 Sbjct: 216 - 274 Query: 289 LLAEHGYTQYSMRRFA-----RATAGTHKSII----DYSC-QEEGMVGLGCGARSYTRNV 338 Sbjct: 275 334 Query: 339 HYASRYGVSRKATESIIADYVAAERYDTADYGIVLSLEEQKRRYILKAVLHSEGLKLADY 398 Sbjct: 335 ------- 387 Query: 399 SGRF 402 Sbjct: 388 391 >CPn0380 [H] COG0635 Coproporphyrinogen III oxidase and related Fe-S oxidoreductases Length = 228 Score = 124 bits (312), Expect = 3e-28, Method: Compositional matrix adjust. Identities = 0/349 (0%), Positives = 0/349 (0%), Gaps = 30/349 (8%) Query: 71 LYMHIPFCGARCGFCNLFTLPDKRAEVHTVYVDALERQA-RQWAAFTGGKPFARFAIGGG 129 + ++ + + V A + ++ G Sbjct: 9 NQVRPVTLTRNYTKHAEGSVLVEFGDT-KVLCTASIEEGVPRFLKGQGQGWITAEYGMLP 67 Query: 130 TPSLLAPAQLRRLFRIAEDIMGLDPASASISVETSPETLTEDKLNILKEHTVDRVSMGIQ 189 + A+ + + D + + + Sbjct: 68 RSTHTRNAREAAKGK------QGGRTMEIQRLIARALRAAVDLKALGEFTITLDCDVLQA 121 Query: 190 SFVAAESAAIYRPQNPDEVYRALELLKLYDFPVLNLDLIYGLPGQTVDSWLYSLEQAVNH 249 ++ + + L + + G + LE + Sbjct: 122 DGGTRTASITGACVALVDALQKLVENGKLKTNPMKGMVAAVSVGIVNGEAVCDLEYVEDS 181 Query: 250 EPEEIFIYPLYTRDHT-------IVKPEDIRRQTDIRHECYRAAQQLLAEHGYTQYSMRR 302 E + +P Sbjct: 182 AAETDMNVVMTEDGRIIEVQGTAEGEPFT-- 239 Query: 303 FARATAGTHKSIIDYSCQEEGMVGLGCGARSYTRNVHYASRYGVSRKATESIIADYVAAE 362 Sbjct: 240 ----------- 288 Query: 363 RYD--TADYGIVLSLEEQKRRYILKAVLHSEGLKLADYSGRFGSSLWRD 409 Sbjct: 289 337 >PA0386 [H] COG0635 Coproporphyrinogen III oxidase and related Fe-S oxidoreductases Length = 228 Score = 123 bits (309), Expect = 5e-28, Method: Compositional matrix adjust. Identities = 0/265 (0%), Positives = 0/265 (0%), Gaps = 6/265 (2%) Query: 71 LYMHIPFCGARCGFCNLFTLPDKRAEVHTVYVDALERQARQWAAFTGGKPFARFAIGGGT 130 + + + G + K ++ Q + + Sbjct: 14 VTLTRNYTKHAEGSVLVEFGDTKVLCTASIEEGVPRFLKGQGQGWITAEYGMLPRSTHTR 73 Query: 131 PSLLAPAQLRRLFRIAEDIMGLDPASASISVETSPETLTEDKLNILKEHTVDRVSMGIQS 190 + A + + + A + + T + + + I Sbjct: 74 NAREAAKGKQGGRTMEIQRLIA-RALRAAVDLKALGEFTITLDCDVLQADGGTRTASITG 132 Query: 191 FVAAESAAIYRPQNPDEVYRALELLKLYDFPVLNLDLIYGLPGQTVDSWLYSLEQAVNHE 250 A A+ + ++ + V ++ + V+ + V Sbjct: 133 ACVALVDALQKLVENGKLKTNPMKGMVAAVSVGIVNGEAVCDLEYVEDSAAETDMNVVMT 192 Query: 251 PEEIFIYPLYTRDHTIV--KPEDIRRQTDIRHECYRAAQQLLAEHGYTQYSMRRFARATA 308 + I T + + I Sbjct: 193 EDGRIIEVQGTAEGEPFTHEELLI- 251 Query: 309 GTHKSIIDYSCQEEGMVGLGCGARS 333 Sbjct: 252 -- 274 >YPO0021 [H] COG0635 Coproporphyrinogen III oxidase and related Fe-S oxidoreductases Length = 228 Score = 123 bits (309), Expect = 6e-28, Method: Compositional matrix adjust. Identities = 0/405 (0%), Positives = 0/405 (0%), Gaps = 61/405 (15%) Query: 36 RNYLYSYPHKTAYRDLNPPVPLEPLWREEPAESFF-------------LYMHIPFCGARC 82 +Y V +E + + I Sbjct: 14 VTLTRNYTKHAEG-----SVLVE--FGDTKVLCTASIEEGVPRFLKGQGQGWITAEYGML 66 Query: 83 GFCNLFTLPDKRAEVHTVYVDALERQARQWAAFTGGKPFARFAIGGGTPSLLAPAQLRRL 142 + A+ ++ A A + A Sbjct: 67 PRSTHTRNAREAAKGKQGGRTMEIQRLIARALRAAVDLKALGEFTITLDCDVLQADGGTR 126 Query: 143 FRIAEDIMGLDPASASISVETSPETLTEDKLNILKEHTVDRVSMGIQSFVAAESAAIYRP 202 A + + + T ++ +V V+ + + Sbjct: 127 TASITGACVALV-DALQKLVENGKLKTNPMKGMVAAVSVGIVNGEAVCDLEYVEDSAAET 185 Query: 203 QNPDEVYRALELLKLYDFPVLNLDLIYGLPGQTVDSWLYSLEQAVNHEPEEIFIY----- 257 Sbjct: 186 245 Query: 258 PLYTRDHTIVKPEDI---RRQTDIRHECYRAAQQLLAEHGYTQYSMRRFAR--------A 306 Sbjct: 246 ---- 301 Query: 307 TAGT-HKSIIDYSCQ-EEGMVGLGCGARSYTRNVHYASRYGVSRKATESIIADYVAAERY 364 Sbjct: 302 ------- 354 Query: 365 DTADYGIVLSLEEQKRRYILKAVL-----------HSEGLKLADY 398 Sbjct: 355 399 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.321 0.137 0.420 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 34,272,856 Number of extensions: 1431251 Number of successful extensions: 7018 Number of sequences better than 1.0e-05: 71 Number of HSP's gapped: 6871 Number of HSP's successfully gapped: 71 Length of query: 461 Length of database: 38,378,431 Length adjustment: 110 Effective length of query: 351 Effective length of database: 25,691,691 Effective search space: 9017783541 Effective search space used: 9017783541 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 118 (50.1 bits)