BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0500.0004.p (253 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value CAC0231 [KG] COG1349 Transcriptional regulators of sugar metabolism 166 3e-41 BS_yulB [KG] COG1349 Transcriptional regulators of sugar metabolism 159 4e-39 BH1553 [KG] COG1349 Transcriptional regulators of sugar metabolism 144 2e-34 lin2465 [KG] COG1349 Transcriptional regulators of sugar metabolism 140 2e-33 agaR [KG] COG1349 Transcriptional regulators of sugar metabolism 135 8e-32 >CAC0231 [KG] COG1349 Transcriptional regulators of sugar metabolism Length = 254 Score = 166 bits (421), Expect = 3e-41, Method: Compositional matrix adjust. Identities = 99/225 (44%), Positives = 131/225 (58%), Gaps = 8/225 (3%) Query: 1 MFEEERKRSIVQFVERHTRASVQELSQDLGVSESTVXXXXXXXXXXXXXXXTHGGAVSLQ 60 MF EER++ I ++R V ELS VSE+T+ THGGAV + Sbjct: 1 MFAEERQKEIKAILDREGSIKVNELSVHFDVSEATIRRDLKEMEDRRILKRTHGGAVPID 60 Query: 61 SVNFEAAFPDKADRFLEEKQRIARKAVEMIQEGDAILLDGGTTTLQIARALKTFSNLKVI 120 NFEA+F DK D EK I + A MI+ GD I+LD GTTTL+IA+ + ++ VI Sbjct: 61 ITNFEASFVDKKDEGQVEKLAIGKYAANMIKNGDTIILDSGTTTLEIAKNIDA-EDITVI 119 Query: 121 TNSMIALNEL---KDCRNIEVSITGGMLRPDTLAFVGPMTERSLEMVRVDKAFIGTNGLD 177 TNS+ +EL KD + IE+ + GG+LRP+T A VG + E + RVDKAFIG NG+ Sbjct: 120 TNSIDIASELLNRKD-KKIELIVAGGILRPNTRAMVGNLCESVFKNFRVDKAFIGANGIT 178 Query: 178 IHEGITTPNMLEAATKRKMISVAKQAILLADHSKIGQVSF---CK 219 EGITTPN EA K+ MI+ A + I++AD SK + F CK Sbjct: 179 SIEGITTPNFTEAQAKKAMINAANKVIVVADSSKFENICFSMICK 223 >BS_yulB [KG] COG1349 Transcriptional regulators of sugar metabolism Length = 258 Score = 159 bits (402), Expect = 4e-39, Method: Compositional matrix adjust. Identities = 92/253 (36%), Positives = 133/253 (52%), Gaps = 1/253 (0%) Query: 1 MFEEERKRSIVQFVERHTRASVQELSQDLGVSESTVXXXXXXXXXXXXXXXTHGGAVSLQ 60 M ER++ IV+ V + V ELS V+E T+ +HGGAVS+Q Sbjct: 1 MLVAERQQKIVEIVNMRSSIRVSELSDIFSVTEETIRRDLEKLEKEHKLSRSHGGAVSIQ 60 Query: 61 SVNFEAAFPDKADRFLEEKQRIARKAVEMIQEGDAILLDGGTTTLQIARALKTFSNLKVI 120 E F ++ + EK+ IA +A + ++ GD I+LD TT +A+ L L VI Sbjct: 61 QKESEIHFSEREITNVIEKKAIAHEAAKYVKSGDRIILDASTTAWYMAKILPDI-ELTVI 119 Query: 121 TNSMIALNELKDCRNIEVSITGGMLRPDTLAFVGPMTERSLEMVRVDKAFIGTNGLDIHE 180 TNSM A EL + NI V TGG+L +L+F GP+ ERSLE V+K F+ G D+H Sbjct: 120 TNSMKAAIELSNKENISVISTGGILLEKSLSFAGPLAERSLETYHVNKTFLSCKGFDVHN 179 Query: 181 GITTPNMLEAATKRKMISVAKQAILLADHSKIGQVSFCKVGDLQEIDHCILDTGAPEGFI 240 G++ N +A K++MI + Q IL+AD SK G F + LQ++ I D+G + Sbjct: 180 GMSDSNEWQALLKKRMIERSDQTILMADSSKWGNREFSHIASLQDVSRLITDSGLDPASV 239 Query: 241 RGLEGLDLDYTLV 253 + LE + T V Sbjct: 240 KALEDKKVKVTAV 252 >BH1553 [KG] COG1349 Transcriptional regulators of sugar metabolism Length = 251 Score = 144 bits (362), Expect = 2e-34, Method: Compositional matrix adjust. Identities = 87/249 (34%), Positives = 129/249 (51%), Gaps = 2/249 (0%) Query: 1 MFEEERKRSIVQFVERHTRASVQELSQDLGVSESTVXXXXXXXXXXXXXXXTHGGAVSLQ 60 M ER I+ V V ELSQ V+E T+ +HGGAVS++ Sbjct: 1 MLVAERHEKIIALVTEKGSVRVSELSQLFNVTEETIRRDLEKLESERKLQRSHGGAVSIK 60 Query: 61 SVNFEAAFPDKADRFLEEKQRIARKAVEMIQEGDAILLDGGTTTLQIARALKTFSNLKVI 120 + EA + ++ R + EKQ +A +AV + D I+LD TT +A+ L L V+ Sbjct: 61 E-DTEAPYFEREIRNVNEKQAVAAQAVTYVTTNDRIILDASTTAWYMAKRLPDVP-LTVL 118 Query: 121 TNSMIALNELKDCRNIEVSITGGMLRPDTLAFVGPMTERSLEMVRVDKAFIGTNGLDIHE 180 TNSM EL I V GG L +L+FVGP T ++LE+ V+KAFI G+ Sbjct: 119 TNSMKVAMELAKREKITVITVGGTLLRKSLSFVGPQTNQTLELYHVNKAFISCQGVHAKR 178 Query: 181 GITTPNMLEAATKRKMISVAKQAILLADHSKIGQVSFCKVGDLQEIDHCILDTGAPEGFI 240 GI+ N ++A K+KMI ++ LLADH+K G+ +F ++ ++ ID I D+ E I Sbjct: 179 GISDSNEMQALVKQKMIDISDHVFLLADHTKFGKQAFSRITSMETIDTIITDSKTSEEQI 238 Query: 241 RGLEGLDLD 249 + L++D Sbjct: 239 SDFQELEMD 247 >lin2465 [KG] COG1349 Transcriptional regulators of sugar metabolism Length = 252 Score = 140 bits (353), Expect = 2e-33, Method: Compositional matrix adjust. Identities = 85/230 (36%), Positives = 126/230 (54%), Gaps = 1/230 (0%) Query: 1 MFEEERKRSIVQFVERHTRASVQELSQDLGVSESTVXXXXXXXXXXXXXXXTHGGAVSLQ 60 M ERKR+IVQ+V+ A+V EL++ V E+T+ THGG + + Sbjct: 1 MLSIERKRAIVQYVKSRKIATVSELAKHFEVHEATIRRDLTSLEKDKKLKRTHGGVMIEE 60 Query: 61 SVNFEAAFPDKADRFLEEKQRIARKAVEMIQEGDAILLDGGTTTLQIARALKTFSNLKVI 120 V E + +++ EEKQRIA A M+++GD I+LD GTTT IA ALK S L VI Sbjct: 61 KVVSEPNWKKRSEVRYEEKQRIATLAATMVKDGDTIILDAGTTTGHIATALKDRSKLTVI 120 Query: 121 TNSMIALNELKDCRNIEVSITGGMLRPDTLAFVGPMTERSLEMVRVDKAFIGTNGLDIHE 180 TN I + + +V +TGG++ P+T G +T +L+ + V KAF+ T LDI + Sbjct: 121 TND-INVASIMRFSPSKVIVTGGVIYPETFILNGMITSGTLQSIHVHKAFVTTPALDIDK 179 Query: 181 GITTPNMLEAATKRKMISVAKQAILLADHSKIGQVSFCKVGDLQEIDHCI 230 G+ + K++M+ A + IL+ DH+K G++S K L EI I Sbjct: 180 GLMHYDEYLIPAKQQMLHSADEVILVTDHTKFGRISLYKYAALDEISSII 229 >agaR [KG] COG1349 Transcriptional regulators of sugar metabolism Length = 269 Score = 135 bits (339), Expect = 8e-32, Method: Compositional matrix adjust. Identities = 82/251 (32%), Positives = 131/251 (52%), Gaps = 2/251 (0%) Query: 5 ERKRSIVQFVERHTRASVQELSQDLGVSESTVXXXXXXXXXXXXXXXTHGGAVSLQSV-- 62 ER+ I+Q + + V +LS GVS T+ +GGA+ S Sbjct: 17 ERREQIIQRLRQQGSVQVNDLSALYGVSTVTIRNDLAFLEKQGIAVRAYGGALICDSTTP 76 Query: 63 NFEAAFPDKADRFLEEKQRIARKAVEMIQEGDAILLDGGTTTLQIARALKTFSNLKVITN 122 + E + DK+ K+ +A+ AVE+IQ G ++LD GTTT +IAR ++ +++ +TN Sbjct: 77 SVEPSVEDKSALNTAMKRSVAKAAVELIQPGHRVILDSGTTTFEIARLMRKHTDVIAMTN 136 Query: 123 SMIALNELKDCRNIEVSITGGMLRPDTLAFVGPMTERSLEMVRVDKAFIGTNGLDIHEGI 182 M N L + +E+ +TGG LR + +F G E+SL+ D F+G + +D+ G+ Sbjct: 137 GMNVANALLEAEGVELLMTGGHLRRQSQSFYGDQAEQSLQNYHFDMLFLGVDAIDLERGV 196 Query: 183 TTPNMLEAATKRKMISVAKQAILLADHSKIGQVSFCKVGDLQEIDHCILDTGAPEGFIRG 242 +T N EA R+M VA++ I++ D SK + S K+ D Q ID I+D G P + G Sbjct: 197 STHNEDEARLNRRMCEVAERIIVVTDSSKFNRSSLHKIIDTQRIDMIIVDEGIPADSLEG 256 Query: 243 LEGLDLDYTLV 253 L ++ LV Sbjct: 257 LRKAGVEVILV 267 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.319 0.135 0.370 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 15,581,331 Number of extensions: 520601 Number of successful extensions: 3641 Number of sequences better than 1.0e-05: 123 Number of HSP's gapped: 3501 Number of HSP's successfully gapped: 123 Length of query: 253 Length of database: 38,378,431 Length adjustment: 104 Effective length of query: 149 Effective length of database: 26,383,695 Effective search space: 3931170555 Effective search space used: 3931170555 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 114 (48.5 bits)