BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0498.0008.p (504 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value BH2728 [T] COG4753 Response regulator containing CheY-like recei... 108 3e-23 BH2109 [T] COG4753 Response regulator containing CheY-like recei... 105 2e-22 BH1123 [T] COG4753 Response regulator containing CheY-like recei... 97 5e-20 BH1910 [T] COG4753 Response regulator containing CheY-like recei... 92 2e-18 SP0661 [T] COG4753 Response regulator containing CheY-like recei... 84 7e-16 >BH2728 [T] COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain Length = 510 Score = 108 bits (269), Expect = 3e-23, Method: Compositional matrix adjust. Identities = 50/124 (40%), Positives = 80/124 (64%) Query: 1 MWKILLVEDEPFVRRSIRQSIRWEEHGFSITGEATHGQEALELMDRLQPDIVITDIFMPY 60 M +L+V+DE +R+ I WE+ GF I GEA +G++ALEL+ + +P IV+TDI MP Sbjct: 1 MCNVLIVDDEKLIRQGIINFFDWEKEGFQIVGEAANGKDALELISKNEPHIVMTDIVMPV 60 Query: 61 MDGLELIQAARAKGFEGSFIMLTCAGEFEYARLALEYGASSYILKLSMSDEELLQALNKA 120 MDG++L++ + E I+L+ EFEY R G + YILK +++++LL+ L++ Sbjct: 61 MDGIDLVKRVKRDFPEVEIIVLSSFEEFEYVRSTFHSGVADYILKPRLNEKDLLKTLSEV 120 Query: 121 RAKL 124 R K+ Sbjct: 121 RGKI 124 Score = 76.3 bits (186), Expect = 1e-13, Method: Compositional matrix adjust. Identities = 34/100 (34%), Positives = 63/100 (63%) Query: 393 INTMIRYLLHHYDEDISLQAMAQYVNMDENYLSGLFKKKTGETFINYLQHIRVNEARFYL 452 I M+ Y+ H+ E +SL +A Y + + +YLS F++ E F YL +R+ +A+ +L Sbjct: 402 IQKMLAYIEEHHSEPLSLSQLANYFHFNPSYLSAYFRQHHDEGFSEYLNKVRIRKAKEWL 461 Query: 453 EQTDLTVAEIGERVGFANPSYFFKIFKRWTKLTPNEYRQQ 492 + + + ++EI VG+++ SYF K+FK+ T + P+ YR++ Sbjct: 462 KSSTIPISEIYALVGYSDHSYFCKVFKKRTGMPPSRYRRE 501 >BH2109 [T] COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain Length = 525 Score = 105 bits (262), Expect = 2e-22, Method: Compositional matrix adjust. Identities = 57/149 (38%), Positives = 89/149 (59%), Gaps = 6/149 (4%) Query: 1 MWKILLVEDEPFVRRSIRQSIRWEEHGFSITGEATHGQEALELMDRLQPDIVITDIFMPY 60 M+K+LL +DE FVR ++ I WE+ G+ + EA +G++A +L+ ++PD+VITDI MP Sbjct: 1 MYKVLLADDEFFVRHGLKSLIEWEKCGYEVAAEADNGEDAFKLVQEIKPDLVITDIRMPV 60 Query: 61 MDGLELIQAARAK-GFEGSFIMLTCAGEFEYARLALEYGASSYILKLSMSDEELLQALNK 119 DGL+LIQ F FI+++ +F YA+ A+ +GA ++LK + +EL AL K Sbjct: 61 FDGLQLIQKVNETLSFNTKFIIISGYNDFSYAQKAVRFGAVDFVLK-PIDQDELEAALIK 119 Query: 120 ARAKL----MKRVEQQDRLEDQLFREAAG 144 A L +Q+ L DQ+F + G Sbjct: 120 LAATLDQEKATNSDQEKVLLDQIFIHSLG 148 Score = 85.9 bits (211), Expect = 1e-16, Method: Compositional matrix adjust. Identities = 47/128 (36%), Positives = 72/128 (56%) Query: 366 LEQTVARMRTYAKGLGGQRPQETDHPEINTMIRYLLHHYDEDISLQAMAQYVNMDENYLS 425 L+Q + A + + +E +I + Y+ +HY E+ISL+++A M+ Y+ Sbjct: 396 LKQVFTKFVLEAAVIIQELRKENMKSDIYKVKTYIENHYHENISLKSIASLFYMNPVYMG 455 Query: 426 GLFKKKTGETFINYLQHIRVNEARFYLEQTDLTVAEIGERVGFANPSYFFKIFKRWTKLT 485 LFKK G F YL +R+NEA+ L QTD+ V E+ ERVGF + YF F++ K+T Sbjct: 456 QLFKKTFGVYFKEYLLKLRMNEAKKLLRQTDMRVYEVAERVGFGSTDYFVTQFEKINKMT 515 Query: 486 PNEYRQQC 493 P EYR + Sbjct: 516 PTEYRNKL 523 >BH1123 [T] COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain Length = 526 Score = 97.4 bits (241), Expect = 5e-20, Method: Compositional matrix adjust. Identities = 48/136 (35%), Positives = 82/136 (60%), Gaps = 1/136 (0%) Query: 1 MWKILLVEDEPFVRRSIRQSIRWEEHGFSITGEATHGQEALELMDRLQPDIVITDIFMPY 60 MWK+++++DE V R +++ I W+ G GEA +G+ L+++ P IV+TDI+MP Sbjct: 1 MWKVVIIDDEEHVVRGLKKIISWKALGCECVGEAANGRRGLDIVRETSPHIVLTDIYMPI 60 Query: 61 MDGLELIQAARAKGFEGSFIMLTCAGEFEYARLALEYGASSYILKLSMSDEELLQALNKA 120 M GL++IQ R GF+G ++L+ EFE+AR A++ + Y+ K + D + L + Sbjct: 61 MYGLDMIQILREDGFDGEVVILSGYSEFEHARKAMQLNITDYLSKPASVD-TIETVLKRV 119 Query: 121 RAKLMKRVEQQDRLED 136 KL ++ QQ L++ Sbjct: 120 INKLEEKQRQQGYLQE 135 Score = 79.7 bits (195), Expect = 1e-14, Method: Compositional matrix adjust. Identities = 35/100 (35%), Positives = 64/100 (64%) Query: 393 INTMIRYLLHHYDEDISLQAMAQYVNMDENYLSGLFKKKTGETFINYLQHIRVNEARFYL 452 I ++ Y+ H E+I+LQ +A + + NYL +FKK GE+F NY+ +R+ +A+ + Sbjct: 426 IEQVMIYIEKHLAENITLQDIADELYISRNYLGQIFKKVVGESFKNYVTRLRMEKAKKMI 485 Query: 453 EQTDLTVAEIGERVGFANPSYFFKIFKRWTKLTPNEYRQQ 492 ++ + + E+ E+VG+ NP+YF +FK++T TP + Q+ Sbjct: 486 QEGNFLIYEVSEKVGYVNPAYFTTMFKKYTGYTPRDLIQK 525 >BH1910 [T] COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain Length = 506 Score = 92.4 bits (228), Expect = 2e-18, Method: Compositional matrix adjust. Identities = 46/135 (34%), Positives = 80/135 (59%), Gaps = 1/135 (0%) Query: 1 MWKILLVEDEPFVRRSIRQSIRWEEHGFSITGEATHGQEALELMDRLQPDIVITDIFMPY 60 M+ +++V+DE VR ++ I WEE+GF + A +G+E +L PD++I DI MP Sbjct: 1 MYDVMIVDDEAMVREGLKALISWEEYGFRVIDTARNGKEGFTKYRQLSPDLMIVDIRMPE 60 Query: 61 MDGLELIQAARAKGFEGSFIMLTCAGEFEYARLALEYGASSYILKLSMSDEELLQALNKA 120 +DGL LI++ RA+ FI+L+ +F YA+ AL Y+LK + ++EL+ +L K Sbjct: 61 VDGLSLIESIRAEDSAIHFIILSGHSDFNYAKKALGCQCDDYLLK-PLDEDELIDSLKKV 119 Query: 121 RAKLMKRVEQQDRLE 135 ++ + + + +E Sbjct: 120 YGRITRHHQVHELVE 134 Score = 65.9 bits (159), Expect = 2e-10, Method: Compositional matrix adjust. Identities = 32/100 (32%), Positives = 56/100 (56%), Gaps = 1/100 (1%) Query: 393 INTMIRYLLHHYDEDISLQAMAQYVNMDENYLSGLFKKKTGETFINYLQHIRVNEARFYL 452 + MI + Y +++ L+ +A N + YL LFK TGE F YL +R+ + L Sbjct: 399 LRKMIALIHKDYAKNLRLETLASVFNYNRAYLGKLFKNYTGEYFNTYLDKVRIENGKRLL 458 Query: 453 EQTDLTVAEIGERVGFANPSYFFKIFKRWTKLTPNEYRQQ 492 Q V E+ E++G+AN YF + FK++ ++P+ +R++ Sbjct: 459 -QKGYKVYEVAEKIGYANVDYFHRKFKKYVGVSPSTFRKR 497 >SP0661 [T] COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain Length = 245 Score = 83.6 bits (205), Expect = 7e-16, Method: Compositional matrix adjust. Identities = 48/149 (32%), Positives = 87/149 (58%), Gaps = 2/149 (1%) Query: 2 WKILLVEDEPFVRRSIRQSIRWEEHGFSITGEATHGQEALELMDRLQPDIVITDIFMPYM 61 + IL+VEDE VR+ + + + + I G+A +G++A EL+ + PDI++TDI MP++ Sbjct: 3 YTILIVEDEYLVRQGLTKLVNVAAYDMEIIGQAENGRQAWELIQKQVPDIILTDINMPHL 62 Query: 62 DGLELIQAARAKGFEGSFIMLTCAGEFEYARLALEYGASSYILKLSMSDEELLQALNKAR 121 +G++L R + + LT +F+YA A++ G Y+LK S +++ + L K + Sbjct: 63 NGIQLASLVRETYPQVHLVFLTGYDDFDYALSAVKLGVDDYLLK-PFSRQDIEEMLGKIK 121 Query: 122 AKLMKRVEQQDRLEDQLFREAAGYMWRSL 150 KL K E++++L+D L G M + + Sbjct: 122 QKLDKE-EKEEQLQDLLTNRFEGNMAQKI 149 Score = 55.8 bits (133), Expect = 2e-07, Method: Compositional matrix adjust. Identities = 34/90 (37%), Positives = 53/90 (58%) Query: 402 HHYDEDISLQAMAQYVNMDENYLSGLFKKKTGETFINYLQHIRVNEARFYLEQTDLTVAE 461 H D SL+++A + YLS L KK+ G F +YL RV +A+ L TDL + E Sbjct: 152 HLADSQFSLKSLASDLGFSPTYLSSLIKKELGLPFQDYLVRERVKQAKLLLLTTDLKIYE 211 Query: 462 IGERVGFANPSYFFKIFKRWTKLTPNEYRQ 491 I E+VGF + +YF + FK+ +TP ++++ Sbjct: 212 IAEKVGFEDMNYFTQRFKQIAGVTPRQFKK 241 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.321 0.137 0.414 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 38,192,472 Number of extensions: 1650785 Number of successful extensions: 6808 Number of sequences better than 1.0e-05: 316 Number of HSP's gapped: 6884 Number of HSP's successfully gapped: 328 Length of query: 504 Length of database: 38,378,431 Length adjustment: 111 Effective length of query: 393 Effective length of database: 25,576,357 Effective search space: 10051508301 Effective search space used: 10051508301 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.9 bits) S2: 118 (50.1 bits)