BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0493.0026.p (287 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value all2672 [V] COG1131 ABC-type multidrug transport system, ATPase ... 201 8e-52 BB0754 [V] COG1131 ABC-type multidrug transport system, ATPase c... 169 6e-42 MTH1370 [V] COG1131 ABC-type multidrug transport system, ATPase ... 167 3e-41 BH0290 [V] COG1131 ABC-type multidrug transport system, ATPase c... 164 1e-40 PH1366 [V] COG1131 ABC-type multidrug transport system, ATPase c... 160 2e-39 >all2672 [V] COG1131 ABC-type multidrug transport system, ATPase component Length = 293 Score = 201 bits (512), Expect = 8e-52, Method: Compositional matrix adjust. Identities = 101/266 (37%), Positives = 163/266 (61%), Gaps = 6/266 (2%) Query: 16 RAIDELNFTLPEGVYGLLGDNGAGKSTLMRILVAVDHQTSGKVSFNGKDIFHMNDDYRNL 75 +A+ +++ + G++GLLG NGAGKS+LMR L + SG + +G + R++ Sbjct: 16 QALRDISLKIDYGIFGLLGPNGAGKSSLMRTLATLQDADSGSIELDGVNFLKNPQSARSI 75 Query: 76 VGYIPQDFEVYPAYTATEYLEYMGALKG-LSKKELKHKVPEVLKFVNLEKVANKKVKTFS 134 +GY+PQDF VYP+ +A + L+ + KG + ++ + V + L+ VNL + +K+ TFS Sbjct: 76 LGYLPQDFGVYPSVSAEDLLDQLAVFKGFIHHQQRREIVAQQLQLVNLYEQRQQKLGTFS 135 Query: 135 GGMKRRVGIAQAIINDPKILIFDEPTAGLDPHERIRFSNIISEMGQDKIILFSTHIISDI 194 GGM++R GIAQA++ PK++I DEPTAGLDP ERIRF N++SE+ QD+++L STHI+ D+ Sbjct: 136 GGMRQRFGIAQALLGSPKLVIVDEPTAGLDPAERIRFHNLLSEISQDRVLLLSTHIVEDV 195 Query: 195 EAITTNVIILNQGKIKEQGNVQKMLSGIKGKVFTEEMDRERLASFKKEHLIVRIRQEENI 254 + N+ I+N+G+I G+ Q +++ + G+V+T S +E ++ R Sbjct: 196 AELCPNMAIMNRGEILRSGSPQALINALNGRVWTALHSE---TSNVEELTVITSRMSRGE 252 Query: 255 VSVRYLGEQESGAIV--CEPTLEDYY 278 VR L + + G EP L D Y Sbjct: 253 RWVRVLSDSQPGKDFQPVEPDLNDVY 278 >BB0754 [V] COG1131 ABC-type multidrug transport system, ATPase component Length = 309 Score = 169 bits (427), Expect = 6e-42, Method: Compositional matrix adjust. Identities = 83/208 (39%), Positives = 135/208 (64%), Gaps = 3/208 (1%) Query: 3 IKAENLTRTFGTKRAIDELNFTLPEG-VYGLLGDNGAGKSTLMRILVAVDHQTSGKVSFN 61 I E +T+ +G A+ ++F + EG V G+LG NGAGKSTL++IL + + + G V Sbjct: 2 INVEKVTKMYGPFTALFNVSFKVEEGEVLGILGPNGAGKSTLIKILTSFHYPSKGNVKIF 61 Query: 62 GKDIFHMNDDYRNLVGYIPQDFEVYPAYTATEYLEYMGALKGLSKKELKHKVPEVLKFVN 121 GKDI + + +GY+P+ +YP + EYL+++ +KG+ K+LK ++ V+ Sbjct: 62 GKDIVEHSKEILQQIGYVPEKLALYPELSVKEYLKFISEIKGV--KKLKKEIDRVISIFK 119 Query: 122 LEKVANKKVKTFSGGMKRRVGIAQAIINDPKILIFDEPTAGLDPHERIRFSNIISEMGQD 181 L++V +K + S G ++RVGIA A+IN+PK++I DEPT GLDP++ I F + E+ ++ Sbjct: 120 LKEVEDKLISQLSKGFRQRVGIAGALINNPKLVILDEPTNGLDPNQIIEFKEFLRELAKE 179 Query: 182 KIILFSTHIISDIEAITTNVIILNQGKI 209 ILFS+HI+S++E+I +II+N G I Sbjct: 180 STILFSSHILSEVESICKRIIIVNNGVI 207 >MTH1370 [V] COG1131 ABC-type multidrug transport system, ATPase component Length = 268 Score = 167 bits (422), Expect = 3e-41, Method: Compositional matrix adjust. Identities = 8/228 (3%), Positives = 31/228 (13%), Gaps = 1/228 (0%) Query: 3 IKAENLTRTFGTKRAIDELNFTLPEG-VYGLLGDNGAGKSTLMRILVAVDHQTSGKVSFN 61 + T + + ++ + + Sbjct: 19 GDLKIKTYKVVLIARAASIFGVKRIVIYHDDADGEARFIRDILTYMDTPQYLRRKVFPIM 78 Query: 62 GKDIFHMNDDYRNLVGYIPQDFEVYPAYTATEYLEYMGALKGLSKKELKHKVPEVLKFVN 121 + + + E L Sbjct: 79 RELKHVGILPPLRTPHHPTGKPVTGEYRQGLTVKRVKKGTLVDIGADKLALCREKLTVNR 138 Query: 122 LEKVANKKVKTFSGGMKRRVGIAQAIINDPKILIFDEPTAGLDPHERIRFSNIISEMGQD 181 + ++ + + + ++ + Sbjct: 139 IMSFRVVRLGKEILIEPDEPEDRYWGYEVLDTRRNLAESLKTVGADVVVATSRNASPITS 198 Query: 182 KIILFSTHIISDIEAITTNVIILNQGKIKEQGNVQKMLSGIKGKVFTE 229 + T + EA + L G + Sbjct: 199 ILDEVKTRMRGAREAAILFGGPYKGLPEIDADIWVNTLPGQCTETVRT 246 >BH0290 [V] COG1131 ABC-type multidrug transport system, ATPase component Length = 301 Score = 164 bits (415), Expect = 1e-40, Method: Compositional matrix adjust. Identities = 90/237 (37%), Positives = 142/237 (59%), Gaps = 6/237 (2%) Query: 1 MEIKAENLTRTFGTKRAIDELNFTLPEG-VYGLLGDNGAGKSTLMRILVAVDHQTSGKVS 59 M+++ +++T+ + K A+ + + L G GL+G NGAGK+TL++++ + T G + Sbjct: 1 MKLEIKSVTKKYKEKTAVHDFSMDLLSGECVGLIGPNGAGKTTLIKMITNILDPTRGDIL 60 Query: 60 FNGKDIFHMNDDYRNLVGYIPQDFEVYPAYTATEYLEYMGALKGLSKKELKHKVPEVLKF 119 NGK I M + +GY+PQ + Y TA+E L +MG L G+SKK+L +PE+L Sbjct: 61 LNGKRISEMKRE----IGYLPQYPDFYQWMTASETLLFMGQLSGISKKKLTKSIPEILSK 116 Query: 120 VNLEKVANKKVKTFSGGMKRRVGIAQAIINDPKILIFDEPTAGLDPHERIRFSNIISEMG 179 V L N KV TFSGGMK+R+GIAQA+++ P ++ DEP + LDP R NII E+ Sbjct: 117 VGLRGEENSKVSTFSGGMKQRLGIAQALLHKPSFIVMDEPVSALDPIGRREVLNIIEEIK 176 Query: 180 QDKIILFSTHIISDIEAITTNVIILNQGKIKEQGNVQKMLS-GIKGKVFTEEMDRER 235 +D IL STHI++D E I ++++ G+ E + ++L+ K K+ E D + Sbjct: 177 KDSTILLSTHILADAEEICERLVMIKNGEKIEDTTMMELLNRNSKNKIRVEITDESK 233 >PH1366 [V] COG1131 ABC-type multidrug transport system, ATPase component Length = 308 Score = 160 bits (406), Expect = 2e-39, Method: Compositional matrix adjust. Identities = 85/218 (38%), Positives = 138/218 (63%), Gaps = 2/218 (0%) Query: 3 IKAENLTRTFGTKRAIDELNFTLPEG-VYGLLGDNGAGKSTLMRILVAVDHQTSGKVSFN 61 I+ E LT+++G +AID L+F + EG V+G LG NGAGK+T + ++ + SG V Sbjct: 4 IEVEKLTKSYGKFKAIDNLSFVVDEGIVFGFLGPNGAGKTTTILSMLGIIIPDSGDVRIL 63 Query: 62 GKDIFHMNDDYRNLVGYIPQDFEVYPAYTATEYLEYMGALKGLSKKELKHKVPEVLKFVN 121 G DIF + +G++P++ +Y TA L++ + +SK+E + ++ E+LK V Sbjct: 64 GYDIFKEPLKAKERLGFLPENATIYEELTAWRNLDFFASFYRMSKQEKEKRIEELLKLVG 123 Query: 122 LEKVANKKVKTFSGGMKRRVGIAQAIINDPKILIFDEPTAGLDPHERIRFSNIISEM-GQ 180 L V +K KTFS GM++R+ +AQA+INDP++LI DEPT+GLDP +II E Q Sbjct: 124 LWDVRYRKAKTFSKGMRQRLLLAQALINDPELLILDEPTSGLDPEGARLVKDIIREQRKQ 183 Query: 181 DKIILFSTHIISDIEAITTNVIILNQGKIKEQGNVQKM 218 K + FS+HI+S++E + V I+ +GK++ G ++++ Sbjct: 184 GKTVFFSSHILSEVEELADKVGIIVKGKLRTVGTLEEI 221 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.318 0.138 0.384 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 21,812,403 Number of extensions: 886297 Number of successful extensions: 8099 Number of sequences better than 1.0e-05: 2160 Number of HSP's gapped: 5121 Number of HSP's successfully gapped: 2350 Length of query: 287 Length of database: 38,378,431 Length adjustment: 105 Effective length of query: 182 Effective length of database: 26,268,361 Effective search space: 4780841702 Effective search space used: 4780841702 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 115 (48.9 bits)