BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0493.0007.p (310 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value CAC0169 [V] COG1131 ABC-type multidrug transport system, ATPase ... 481 e-136 BS_yfiL [V] COG1131 ABC-type multidrug transport system, ATPase ... 290 3e-78 CAC0241 [V] COG1131 ABC-type multidrug transport system, ATPase ... 279 3e-75 SPy0744 [V] COG1131 ABC-type multidrug transport system, ATPase ... 249 5e-66 CAC0236 [V] COG1131 ABC-type multidrug transport system, ATPase ... 245 6e-65 >CAC0169 [V] COG1131 ABC-type multidrug transport system, ATPase component Length = 310 Score = 481 bits (1237), Expect = e-136, Method: Compositional matrix adjust. Identities = 232/309 (75%), Positives = 272/309 (88%) Query: 1 MLELTNLTKKYNDITVVNNISLNVKRGEIFGLLGPNGAGKSTTVSMISTVLTPTSGSITI 60 MLELTN+TKKY D T VNNIS ++ GE+FGLLGPNGAGKST VSMISTV++PTSG IT+ Sbjct: 1 MLELTNITKKYGDFTAVNNISFKIEDGEVFGLLGPNGAGKSTIVSMISTVISPTSGDITV 60 Query: 61 DNKSLREKPADIKKIMGIVPQDLALYQALSAKENLEFFGSLYGLSGKKLKNRTNEVLDII 120 DNK LR+KP +IKK+MGIVPQD+ALY++LSAK+NLEFFG LYGL+GK+LK R NEVL II Sbjct: 61 DNKLLRQKPTEIKKVMGIVPQDIALYESLSAKDNLEFFGCLYGLNGKELKERVNEVLKII 120 Query: 121 ELQDKKNQDVAEFSGGMKRRVNIGVALMNDPKLLILDEPTVGIDPQSRNHILETVKKLNQ 180 EL+DKK+Q V EFSGGMKRRVNIGVALMN+PKLLILDEPTVGIDPQSRNHILETVKKLN+ Sbjct: 121 ELEDKKDQAVEEFSGGMKRRVNIGVALMNNPKLLILDEPTVGIDPQSRNHILETVKKLNK 180 Query: 181 DRGMTVIYTSHYMEEVEYLCKNVAIIDHGSLIALGTKEELKQSLAACDTLTVNYSEASEG 240 +RGMTVIYTSHYMEEVEYLCK +AI+DHG LIALGTK+ELK+ A DTLTV YS +G Sbjct: 181 ERGMTVIYTSHYMEEVEYLCKRIAIVDHGKLIALGTKDELKEKSKAKDTLTVIYSNGDKG 240 Query: 241 ALEQLNRIPGISKVNIEGNQISMLVSTNDKNVIEIVDEIKKLGIKLTSFKYEEVNLESIF 300 AL+++ I GI V+I NQISMLV + +N+I+IV++++ LG+KLTSFKYEEVNLESIF Sbjct: 241 ALDKIKSINGIENVSISNNQISMLVDQHKRNIIDIVEDVRNLGVKLTSFKYEEVNLESIF 300 Query: 301 LQITGKALR 309 LQITGK+LR Sbjct: 301 LQITGKSLR 309 >BS_yfiL [V] COG1131 ABC-type multidrug transport system, ATPase component Length = 134 Score = 290 bits (741), Expect = 3e-78, Method: Compositional matrix adjust. Identities = 0/311 (0%), Positives = 0/311 (0%), Gaps = 3/311 (0%) Query: 1 MLELTNLTKKYNDITVVNNISLNVKRGEIFGLLGPNGAGKSTTVSMISTVLTPTSGSITI 60 M + KK ++ L + A T+ + I Sbjct: 1 MKTIRYALKKEKEMMKKFIAPLLALLVSGCQIDPYTHAPTLTSTDWYDVGMEDAISGSAI 60 Query: 61 DNKSLREKPADIKKIMGIVPQDLALYQALSAKENLEFFGSLYGLSGKKLKNRTNEVLDII 120 + + + + + + +++ ++ Sbjct: 61 KDDDAFSDSQADRGLYLKGYAEGQKKTCQTDFTYARGLSGKSFPASCNNVENASQLHEVW 120 Query: 121 ELQDKKNQDVAEFSGGMKRRVNIGVALMNDPKLLILDEPTVGIDPQSRNHILETVKKLNQ 180 Sbjct: 121 180 Query: 181 DRGMTVIYTSHYMEEVEYLCKNVAIIDHGSLIALGTKEELKQSLAACDTLTVNYSEASEG 240 Sbjct: 181 - 239 Query: 241 ALEQLNRIPGISKVNIEGNQISMLVST--NDKNVIEIVDEIKKLGIKLTSFKYEEVNLES 298 Sbjct: 240 299 Query: 299 IFLQITGKALR 309 Sbjct: 300 310 >CAC0241 [V] COG1131 ABC-type multidrug transport system, ATPase component Length = 310 Score = 279 bits (714), Expect = 3e-75, Method: Compositional matrix adjust. Identities = 141/309 (45%), Positives = 205/309 (66%), Gaps = 1/309 (0%) Query: 1 MLELTNLTKKYNDITVVNNISLNVKRGEIFGLLGPNGAGKSTTVSMISTVLTPTSGSITI 60 +LE+ NL K Y + T V++++L ++ GEI+GLLGPNGAGKSTT++ I+ + SG I I Sbjct: 2 ILEIKNLKKTYKEFTAVDSLNLKIEDGEIYGLLGPNGAGKSTTINTITGLTKVDSGEIKI 61 Query: 61 DNKSLREKPADIKKIMGIVPQDLALYQALSAKENLEFFGSLYGLSGKKLKNRTNEVLDII 120 K +IK+ +G+VPQD+A++ LSA EN+ FFG L GL G LK R E LD Sbjct: 62 FGKRFNGSDTNIKRNIGVVPQDIAVFSELSAYENVAFFGKLNGLRGAVLKERVKEALDFT 121 Query: 121 ELQDKKNQDVAEFSGGMKRRVNIGVALMNDPKLLILDEPTVGIDPQSRNHILETVKKLNQ 180 L D++ ++SGGM+RR+NI A+++ PKL+I+DEPTVGIDPQSRNHIL++VKKLN+ Sbjct: 122 GLWDRRKSKPGQYSGGMQRRLNIACAIVHRPKLIIMDEPTVGIDPQSRNHILDSVKKLNE 181 Query: 181 DRGMTVIYTSHYMEEVEYLCKNVAIIDHGSLIALGTKEELKQSLAACDTLTVNYSEASEG 240 G T+IYTSHYMEE+E LC + IIDHG IA GTKE+LK+ ++ + + + SE ++ Sbjct: 182 -MGSTIIYTSHYMEEIETLCSKITIIDHGKEIATGTKEQLKEMISNEEKVELELSEVTDD 240 Query: 241 ALEQLNRIPGISKVNIEGNQISMLVSTNDKNVIEIVDEIKKLGIKLTSFKYEEVNLESIF 300 +E + I + K N + ++ N +N+ I +I + K+ S E+ +LE +F Sbjct: 241 LVEAVEGIKNVKKCRRNENMLVIVSDKNSENISTITAKIAEFKSKIISINVEKPSLEGVF 300 Query: 301 LQITGKALR 309 L +TG+ LR Sbjct: 301 LTLTGRKLR 309 >SPy0744 [V] COG1131 ABC-type multidrug transport system, ATPase component Length = 307 Score = 249 bits (635), Expect = 5e-66, Method: Compositional matrix adjust. Identities = 138/315 (43%), Positives = 209/315 (66%), Gaps = 17/315 (5%) Query: 1 MLELTNLTKKY-NDITVVNNISLNVKRGEIFGLLGPNGAGKSTTVSMISTVLTPTSGSIT 59 ++LTN+ K Y N VN++SL+++ G I+GLLGPNGAGKST +++I ++ +SG IT Sbjct: 3 FVQLTNVVKSYKNGKKAVNDVSLSIEAGNIYGLLGPNGAGKSTLINLILGLIPLSSGKIT 62 Query: 60 IDNKSLREKPADIKKI---MGIVPQDLALYQALSAKENLEFFGSLYGLSGKKLKNRTNEV 116 + +S + I+KI +G VPQD+A+Y L+A EN+E FGSLYGL G +LK + + Sbjct: 63 VLGQSQK----TIRKISSQIGYVPQDIAVYPDLTAYENVELFGSLYGLKGAQLKKQVLKS 118 Query: 117 LDIIELQDKKNQDVAEFSGGMKRRVNIGVALMNDPKLLILDEPTVGIDPQSRNHILETVK 176 L+ + L + Q ++FSGGMKRR+NI AL++ PKL+I DEPTVGIDPQSRNHILE+++ Sbjct: 119 LEFVGLHSQAKQFPSQFSGGMKRRLNIACALVHSPKLIIFDEPTVGIDPQSRNHILESIR 178 Query: 177 KLNQDRGMTVIYTSHYMEEVEYLCKNVAIIDHGSLIALGTKEELKQSLAA--CDTLTVNY 234 LN++ G TVIYT+HYMEEVE LC + I+DHG +I G K EL++ A + + V Sbjct: 179 LLNKE-GATVIYTTHYMEEVEALCDYIFIMDHGQVIEEGPKFELEKRYVANLANQIIVTL 237 Query: 235 SEASEGALEQLNRIPGISKVNIEGNQISMLVSTNDKNVIEIVDEIKKLGIKLTSFKYEEV 294 +++ LE ++ P S + +G ++ + + +D + +V ++ + I + ++ + Sbjct: 238 TDSRH--LELADK-PDWSLIE-DGEKLMLKIDNSD--MTSVVHQLTQANITFSEIRHNHL 291 Query: 295 NLESIFLQITGKALR 309 NLE IFL +TGK LR Sbjct: 292 NLEEIFLHLTGKKLR 306 >CAC0236 [V] COG1131 ABC-type multidrug transport system, ATPase component Length = 310 Score = 245 bits (626), Expect = 6e-65, Method: Compositional matrix adjust. Identities = 124/308 (40%), Positives = 201/308 (65%), Gaps = 1/308 (0%) Query: 1 MLELTNLTKKYNDITVVNNISLNVKRGEIFGLLGPNGAGKSTTVSMISTVLTPTSGSITI 60 +LE+ NL K+Y D V+N++L+++ GEI GLLGPNGAGK+T + I + SGSI I Sbjct: 2 LLEIKNLVKRYGDFLAVDNVNLSIEEGEILGLLGPNGAGKTTIIDCIIGLNKIDSGSIRI 61 Query: 61 DNKSLREKPADIKKIMGIVPQDLALYQALSAKENLEFFGSLYGLSGKKLKNRTNEVLDII 120 + IKK +GIV Q +++Y L+ +N+ +FG +YGL GKKLK E L+ + Sbjct: 62 FGMDFLKNEMAIKKSIGIVTQTISVYDDLNVYDNVMYFGGMYGLRGKKLKEYAREALNFV 121 Query: 121 ELQDKKNQDVAEFSGGMKRRVNIGVALMNDPKLLILDEPTVGIDPQSRNHILETVKKLNQ 180 + D + + SGGM RR+NI +++ PKL+I+DEPT GIDP+SR+++LE++K+LN+ Sbjct: 122 GIWDNARKFPKQLSGGMLRRLNIACGIVHKPKLIIMDEPTAGIDPKSRSNLLESIKELNK 181 Query: 181 DRGMTVIYTSHYMEEVEYLCKNVAIIDHGSLIALGTKEELKQSLAACDTLTVNYSEASEG 240 + G T+IYTSHYMEE+E +C ++AII+ G +IA G KEELK A + + + S + Sbjct: 182 N-GATIIYTSHYMEEIERICSSIAIINEGRIIAKGDKEELKSLAAKEEKIKIKPSALNYT 240 Query: 241 ALEQLNRIPGISKVNIEGNQISMLVSTNDKNVIEIVDEIKKLGIKLTSFKYEEVNLESIF 300 ++++ +I G+ + +I + I ++ N KN+ +I+D I G+++ + ++E++F Sbjct: 241 IVDEIKKIYGVKECSINADYIDIVSDKNSKNIAKIIDMIVGSGLEVLDVIIDRPSIETVF 300 Query: 301 LQITGKAL 308 L +TG+ L Sbjct: 301 LALTGRNL 308 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.313 0.133 0.357 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 21,147,387 Number of extensions: 870728 Number of successful extensions: 8839 Number of sequences better than 1.0e-05: 2173 Number of HSP's gapped: 6186 Number of HSP's successfully gapped: 2423 Length of query: 310 Length of database: 38,378,431 Length adjustment: 106 Effective length of query: 204 Effective length of database: 26,153,027 Effective search space: 5335217508 Effective search space used: 5335217508 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.9 bits) S2: 116 (49.3 bits)