BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0490.0015.p (519 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value BH3842 [T] COG4753 Response regulator containing CheY-like recei... 115 1e-25 SP0661 [T] COG4753 Response regulator containing CheY-like recei... 113 6e-25 SPy1587 [T] COG4753 Response regulator containing CheY-like rece... 111 3e-24 BH2109 [T] COG4753 Response regulator containing CheY-like recei... 107 5e-23 BH0793 [T] COG4753 Response regulator containing CheY-like recei... 104 4e-22 >BH3842 [T] COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain Length = 530 Score = 115 bits (289), Expect = 1e-25, Method: Compositional matrix adjust. Identities = 129/536 (24%), Positives = 231/536 (43%), Gaps = 40/536 (7%) Query: 1 MYKLLLVDDERLILEGISQVVDWAQAGTELAGTARNGIEALDQIERLRPDIVITDISMPG 60 M +L+VDDE++ EG+ + + + G A NG +A+++ +PD+++ DI MPG Sbjct: 1 MINVLIVDDEQIEREGLKLFLK-DRPNIHIVGEASNGRQAIEKALETQPDLMMMDIKMPG 59 Query: 61 LDGLGLVERCSVHYPGLKFVMLTGYKDFDYACTAMQHGVKHYLLKPCNEQQIHEALTELV 120 +DG+ V+ P +F+M++ + F+YA M++GVK YLLKP ++ + AL +V Sbjct: 60 VDGVQAVKEIKQQLPETEFIMVSAFDTFEYAREVMRYGVKEYLLKPTTKEDVLTALDRIV 119 Query: 121 QELNELHSREQFMSDMKHRLTKVLPHVKAQFL----------KEWISNKTYGSRDLEYYQ 170 E+ + + ++ RL ++ V+ + + EW+ + + E Y Sbjct: 120 GEIEQAREEKNDQYKLQQRLEQISSFVQTESILYLLMDHIQDYEWMEWNEWLRTEQEGYA 179 Query: 171 ELFGIELGSKNVXXXXXXXXXXXXXXHLFALQNIAGDLLSEVLLSTTIGSQLLILMEQPE 230 +F K + + G L + + IG L ILM Sbjct: 180 VVFSFHQQGKEIRKTEKQQWHARIKKEI-------GLQLPKSTVGPFIGHHLPILM--LT 230 Query: 231 EADNQRDLLERIAGVKEIFFNFYQ----IHVTIAVSDKGRMIHSRSLYRQTLQCMNHRFY 286 E +N ER V ++ Q V V R+ + YR+ L ++ + Sbjct: 231 ENENGMTKQEREQVVIQLLHKVKQAVQPAKVKTGVGGIYRLHFFSTSYREALLALDIIYD 290 Query: 287 LEEGSLI---TGSDIPADE-LSVHSEIDLGEEQICLLVKAGD-QAAVQNELERLFGVLAD 341 ++ S I ADE L + E L E +K+GD + A+Q + +L Sbjct: 291 HKQASYYFYDKNVKIRADEQLPIERENKLIE-----AIKSGDGEKALQAFDHYVQAILRC 345 Query: 342 QRFDINVTRSYVLQLYSAMIRLCSPDERSSFXXXXXXXXXXXXXXXXKAGVMRAAERLTA 401 + ++ R Y+ QL+ + RL + + + + G + Sbjct: 346 SKHPLHDMRKYLQQLFIILGRLLN-EMGLHWETAQDFARFSTVHQVTEHGKSEILHIVRT 404 Query: 402 MYERHFVSRQSSIVDKMLRIIEADYGNSELSLGSVAAEMLYMNPDYLGKIFKKVTGEKFS 461 + E QS ++ + R D+ L+L +A + ++P Y+ K+FK+ FS Sbjct: 405 LQEWRTTDEQSLML--LARDYVHDHFREPLTLDDLAKH-IGLSPYYVSKLFKERFDLTFS 461 Query: 462 NYVTNYRIGKASGHILHSGDVKVFELAELYGFGGNAQYFSQVFKKVTGKTPTDFMK 517 YVT R+ A +L + E+ G+ + YFS+VFKK+TGK+P+D+ K Sbjct: 462 EYVTQLRVEHAK-QLLSLTQKSLKEITYEIGY-KDPNYFSRVFKKLTGKSPSDYRK 515 >SP0661 [T] COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain Length = 245 Score = 113 bits (283), Expect = 6e-25, Method: Compositional matrix adjust. Identities = 56/139 (40%), Positives = 88/139 (63%) Query: 2 YKLLLVDDERLILEGISQVVDWAQAGTELAGTARNGIEALDQIERLRPDIVITDISMPGL 61 Y +L+V+DE L+ +G++++V+ A E+ G A NG +A + I++ PDI++TDI+MP L Sbjct: 3 YTILIVEDEYLVRQGLTKLVNVAAYDMEIIGQAENGRQAWELIQKQVPDIILTDINMPHL 62 Query: 62 DGLGLVERCSVHYPGLKFVMLTGYKDFDYACTAMQHGVKHYLLKPCNEQQIHEALTELVQ 121 +G+ L YP + V LTGY DFDYA +A++ GV YLLKP + Q I E L ++ Q Sbjct: 63 NGIQLASLVRETYPQVHLVFLTGYDDFDYALSAVKLGVDDYLLKPFSRQDIEEMLGKIKQ 122 Query: 122 ELNELHSREQFMSDMKHRL 140 +L++ EQ + +R Sbjct: 123 KLDKEEKEEQLQDLLTNRF 141 Score = 53.5 bits (127), Expect = 7e-07, Method: Compositional matrix adjust. Identities = 34/100 (34%), Positives = 60/100 (60%), Gaps = 3/100 (3%) Query: 418 MLRIIEADYGNSELSLGSVAAEMLYMNPDYLGKIFKKVTGEKFSNYVTNYRIGKASGHIL 477 M + I++ +S+ SL S+A+++ + +P YL + KK G F +Y+ R+ +A +L Sbjct: 145 MAQKIQSHLADSQFSLKSLASDLGF-SPTYLSSLIKKELGLPFQDYLVRERVKQAKLLLL 203 Query: 478 HSGDVKVFELAELYGFGGNAQYFSQVFKKVTGKTPTDFMK 517 + +K++E+AE GF + YF+Q FK++ G TP F K Sbjct: 204 TTD-LKIYEIAEKVGFE-DMNYFTQRFKQIAGVTPRQFKK 241 >SPy1587 [T] COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain Length = 494 Score = 111 bits (277), Expect = 3e-24, Method: Compositional matrix adjust. Identities = 49/124 (39%), Positives = 83/124 (66%) Query: 1 MYKLLLVDDERLILEGISQVVDWAQAGTELAGTARNGIEALDQIERLRPDIVITDISMPG 60 MYK+LLVDDE +IL+G++ ++DW G E+ TAR+G EAL + + D++I+D++MPG Sbjct: 1 MYKVLLVDDEYMILQGLTMIIDWQALGFEVVQTARSGKEALAYLTQYPVDVMISDVTMPG 60 Query: 61 LDGLGLVERCSVHYPGLKFVMLTGYKDFDYACTAMQHGVKHYLLKPCNEQQIHEALTELV 120 + GL L+E ++P L+ ++L+GY++F Y AM+ K YLLKP ++ ++ + + Sbjct: 61 MTGLDLIEAAKTYHPQLQTLILSGYQEFSYVQKAMELETKGYLLKPVDKAELQAKMKQFK 120 Query: 121 QELN 124 L+ Sbjct: 121 DWLD 124 Score = 56.6 bits (135), Expect = 9e-08, Method: Compositional matrix adjust. Identities = 36/106 (33%), Positives = 62/106 (58%), Gaps = 4/106 (3%) Query: 410 RQSSIVDKMLRIIEADYGNSELSLGSVAAEMLYMNPDYLGKIFKKVTGEKFSNYVTNYRI 469 R S +V + + I +Y + EL+L ++A + L++N YLG+ FK T F+ Y+ + RI Sbjct: 378 RYSDLVSETIDCIRKEY-HQELTLKAIA-DRLHVNGVYLGQCFKNETERSFTQYLNHVRI 435 Query: 470 GKASGHILHSGDVKVFELAELYGFGGNAQYFSQVFKKVTGKTPTDF 515 KA +L++ + E+A G+ N YF ++FKK+ G +P +F Sbjct: 436 QKAQQLLLYTNQ-SINEIAYETGYNTN-HYFIKMFKKLNGLSPKEF 479 >BH2109 [T] COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain Length = 525 Score = 107 bits (267), Expect = 5e-23, Method: Compositional matrix adjust. Identities = 47/126 (37%), Positives = 80/126 (63%), Gaps = 1/126 (0%) Query: 1 MYKLLLVDDERLILEGISQVVDWAQAGTELAGTARNGIEALDQIERLRPDIVITDISMPG 60 MYK+LL DDE + G+ +++W + G E+A A NG +A ++ ++PD+VITDI MP Sbjct: 1 MYKVLLADDEFFVRHGLKSLIEWEKCGYEVAAEADNGEDAFKLVQEIKPDLVITDIRMPV 60 Query: 61 LDGLGLVERCSVHYP-GLKFVMLTGYKDFDYACTAMQHGVKHYLLKPCNEQQIHEALTEL 119 DGL L+++ + KF++++GY DF YA A++ G ++LKP ++ ++ AL +L Sbjct: 61 FDGLQLIQKVNETLSFNTKFIIISGYNDFSYAQKAVRFGAVDFVLKPIDQDELEAALIKL 120 Query: 120 VQELNE 125 L++ Sbjct: 121 AATLDQ 126 Score = 66.2 bits (160), Expect = 1e-10, Method: Compositional matrix adjust. Identities = 38/99 (38%), Positives = 59/99 (59%), Gaps = 4/99 (4%) Query: 417 KMLRIIEADYGNSELSLGSVAAEMLYMNPDYLGKIFKKVTGEKFSNYVTNYRIGKASGHI 476 K+ IE Y + +SL S+A+ + YMNP Y+G++FKK G F Y+ R+ +A + Sbjct: 425 KVKTYIENHY-HENISLKSIAS-LFYMNPVYMGQLFKKTFGVYFKEYLLKLRMNEAKK-L 481 Query: 477 LHSGDVKVFELAELYGFGGNAQYFSQVFKKVTGKTPTDF 515 L D++V+E+AE GFG YF F+K+ TPT++ Sbjct: 482 LRQTDMRVYEVAERVGFGS-TDYFVTQFEKINKMTPTEY 519 >BH0793 [T] COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain Length = 508 Score = 104 bits (259), Expect = 4e-22, Method: Compositional matrix adjust. Identities = 48/131 (36%), Positives = 86/131 (65%) Query: 1 MYKLLLVDDERLILEGISQVVDWAQAGTELAGTARNGIEALDQIERLRPDIVITDISMPG 60 M +++LVDDE LILEG+ ++DW Q G E+ TARNG+EAL+ + + D++ITDI MP Sbjct: 1 MIRVMLVDDEPLILEGLKHLIDWGQLGYEIVATARNGVEALEIAKYVSFDLLITDIKMPE 60 Query: 61 LDGLGLVERCSVHYPGLKFVMLTGYKDFDYACTAMQHGVKHYLLKPCNEQQIHEALTELV 120 GL L+ + ++ ++L+G+++F + + G+++YLLKP NE+++ L+ + Sbjct: 61 KTGLELIAALNEREKTIRSIVLSGFQEFHFVKQGLTLGIENYLLKPINEKELISTLSHVK 120 Query: 121 QELNELHSREQ 131 +++N +E+ Sbjct: 121 EKINHAFLKEE 131 Score = 56.2 bits (134), Expect = 1e-07, Method: Compositional matrix adjust. Identities = 34/106 (32%), Positives = 62/106 (58%), Gaps = 4/106 (3%) Query: 412 SSIVDKMLRIIEADYGNSELSLGSVAAEMLYMNPDYLGKIFKKVTGEKFSNYVTNYRIGK 471 S I+ +L+ I + + +LSL ++ ++NP YLG++F++ G F+ Y+ RI + Sbjct: 402 SPIIQTVLQHIHQHF-SQDLSLKTLGHS-FHINPIYLGQLFQREVGCSFTKYLNQLRIDR 459 Query: 472 ASGHILHSGDVKVFELAELYGFGGNAQYFSQVFKKVTGKTPTDFMK 517 A +L+S D + ++ + G+ G+A YF + FKK TPT++ K Sbjct: 460 AKKLLLNSYD-RAGQIGKKVGY-GDATYFYKQFKKYEAMTPTEWRK 503 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.321 0.137 0.391 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 35,314,251 Number of extensions: 1431309 Number of successful extensions: 5956 Number of sequences better than 1.0e-05: 226 Number of HSP's gapped: 6008 Number of HSP's successfully gapped: 237 Length of query: 519 Length of database: 38,378,431 Length adjustment: 111 Effective length of query: 408 Effective length of database: 25,576,357 Effective search space: 10435153656 Effective search space used: 10435153656 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 118 (50.1 bits)