BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0489.0029.p (1551 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value all2635 [Q] COG3321 Polyketide synthase modules and related prot... 999 0.0 all2646 [Q] COG3321 Polyketide synthase modules and related prot... 932 0.0 AGl2329 [Q] COG3321 Polyketide synthase modules and related prot... 714 0.0 AGl2313 [Q] COG3321 Polyketide synthase modules and related prot... 699 0.0 ML2353_1 [Q] COG3321 Polyketide synthase modules and related pro... 622 e-177 >all2635 [Q] COG3321 Polyketide synthase modules and related proteins Length = 1565 Score = 999 bits (2582), Expect = 0.0, Method: Compositional matrix adjust. Identities = 596/1556 (38%), Positives = 834/1556 (53%), Gaps = 109/1556 (7%) Query: 9 EIAVIGMSARVPGAADVHTFWDNLVNGKESITFFTADELLESGIEPAAVSHPDYVRAKGY 68 E+A++GM+ R PGA +V FWDNL NG SI F + ++LL +G++ + +YVRA Sbjct: 38 EVAIVGMAGRFPGAKNVDEFWDNLKNGINSIKFLSNEDLLANGVKAEDLEKQNYVRAYAS 97 Query: 69 LENSDQFDASFFNYSPLEAEVMDPQVRIFHECVWEALEDAGYCPGTYPGLIGXXXXXXAS 128 L D+FDA FF YSP EAE++DPQ R+F EC WEALE+AGY Y G I Sbjct: 98 LAGIDEFDAGFFGYSPREAEILDPQHRLFLECAWEALENAGYDSEQYSGNIAVY------ 151 Query: 129 LYWQALSYLSEGARLLGPFTANQFANKDY-----------------MSTLISHRLNLKGP 171 G L + N +N +Y M T +S++LNL G Sbjct: 152 -----------GGAALNSYLVNLASNSNYRENSDRTQVVISNVMGLMPTRVSYKLNLTGA 200 Query: 172 SLTVNTACSTSLVTIHLAAQALLNGECDIALAGGASITLPLKSGYQYQEGMILSPDGHCK 231 S + T CSTSLV++H+A Q+LLN ECDIALAGG SI + K+GY YQE +LSPDG+C+ Sbjct: 201 SCGIQTGCSTSLVSVHIACQSLLNKECDIALAGGVSIGIGEKAGYLYQEDGVLSPDGYCR 260 Query: 232 AFDEEGQGSVPGNGAGVVVLKRFEEAVQDGDHIYAVIKGSAINNDGNRKSAYTAPSVEGQ 291 AFD +G+V GNG G+VVLKR +A+QDGDHIYA+IK +AINNDG++K TAPSV GQ Sbjct: 261 AFDVNAKGTVFGNGVGIVVLKRLRDAIQDGDHIYAIIKATAINNDGSQKVGLTAPSVTGQ 320 Query: 292 VEVIQTAQQLAEVNAASIQFVETHGTGTVLGDPIELEALKAAFG---NSEGVCRIGSVKS 348 + I TA A++N +IQ++ETHGTGT LGDPIE+ AL AF + + C +GSVK+ Sbjct: 321 AKAITTALTKAKINPETIQYIETHGTGTALGDPIEIAALTKAFSPHTHQKQFCAVGSVKT 380 Query: 349 NIGHLDAAAGVAGFIKATLSLQHRLLPPTLHFTTLNPKINLADSPFVVNGKLSDLSGEGN 408 NIGHLDAAAG++G IK L+L+H+ +PP+L+FT NP+I+ A+SPF VN +L+ + Sbjct: 381 NIGHLDAAAGISGLIKTALALKHKQIPPSLNFTAANPQIDFANSPFFVNTQLTPWINHQH 440 Query: 409 PLRAGVSSFGIGGTNAHIVLEEAXXXXXXXXGR---DSQLILISAKSRSALEQHSSNLAA 465 P RAGVSSFG+GGTNAH +LEEA + + L+ +SAKS ALEQ + NLA Sbjct: 441 PRRAGVSSFGMGGTNAHAILEEAPTQFKIQNSKFKINYHLLCLSAKSEKALEQATINLAT 500 Query: 466 YIRNHPEVPLADLAYTLQVGRTDFEHRRFVVANHTGELPEMLQPLGNEKGKPSRKVFTST 525 +++ HPE+ LAD+AYTLQ+GR F HRR +V + E+L G + ++ + + Sbjct: 501 HLQKHPELNLADVAYTLQIGRRAFNHRRCLVCQTPAQAIEIL------TGVDASQLLSYS 554 Query: 526 VEQENKPIVFMFPGLGNQYVDMGLGLYRTELLFKQELDRCFDLLDSHLDFSMKAILFPQ- 584 E IVFMFPG G+QY++MG LY TE +F++E+D C +LL HL + +ILF Q Sbjct: 555 PENTEPSIVFMFPGQGSQYLNMGQELYNTEPVFRKEIDHCSELLQPHLGCDLPSILFKQD 614 Query: 585 ----------------EARDEAVYKINRIDINQMVVFIFEYALGKYLMELGIKPKYMIGY 628 E R + + Q +F EYAL K + GI+P+ MIG+ Sbjct: 615 NENSPSPQSPVPNLNYELRITNYELLTQTTYAQPALFAVEYALAKLWLSYGIQPQAMIGH 674 Query: 629 SFGEFAAACLAGVFVLEDAIRVIIRRGQMIKGTEEGAMLSVPMTEQELRPLLPPDVSLSI 688 S GE+ AA LAGVF L DA+ ++ +RG++++ G MLSV + ++L+P L D+ +++ Sbjct: 675 SIGEYVAATLAGVFTLADALAIVAQRGKLMQQCPSGVMLSVSLAPEKLQPFLTDDLVIAV 734 Query: 689 VNGPS-CVVGGTRTAVEQFEEQLKSLRQICIRLDTSYALHSAVMEPVRDAFAEEMKQIRL 747 N P CVV GT A+ E+ L RL TS+A HS +ME + ++ I L Sbjct: 735 HNAPELCVVSGTEAAITLLEKLLTHQNITHRRLHTSHAFHSPLMETAVTPLTQILQNISL 794 Query: 748 YPPQIPFISNLSGNWITDEEATDPGYWGQQLTDSIRFADGLKEILKEEALTFLEVGPDRN 807 +PPQIPFISN++G WIT E+AT+P YW L + FA+G+ E+ + F+EVG + Sbjct: 795 HPPQIPFISNVTGTWITPEQATNPNYWATHLRQPVLFAEGITELQQTPNQIFVEVGFGQT 854 Query: 808 LSALLRYFVHRDSSHTILNLIRNPQENVEDQTYLYTRLGQLWGAGHSIEWMKLYAYERRN 867 LS +R F D+ T L+ R+PQ+ D + LGQLW G +I W +LY ++R Sbjct: 855 LSTFVRQF--PDAPPT-LSSGRHPQDTQSDVALICKTLGQLWLRGVTINWSELYTQQQRR 911 Query: 868 RLSLPAYPFERESYGMEGNPFDMLEGQQKGKHSLLPKQPHMEDWFYLPLWQQKALPLASG 927 RL LP YPFER+ Y +E D L L KQ + +WFYLP W+QK L ++ Sbjct: 912 RLPLPTYPFERQRYWVER---DTLPETTSNTSKTLQKQEQISNWFYLPSWRQKPLLRSAA 968 Query: 928 PLGGQLCLLFANDDLISRELLQALRSSGQRVIPVYRGHEFSMHDDGEYTIHPESLADYQQ 987 PL Q L+F + L+Q L+ +GQ V+ V G F+ D Y I P + DY+ Sbjct: 969 PLNKQRYLVFCHAGNAGERLVQHLQETGQEVVTVKPGEGFTQEGDN-YAIAPHNPEDYKT 1027 Query: 988 LFAVLQEKQVEADNLIHLWSLENRVSAPLDAAAFHESQKNGFYSVTYIVQCLHQFSRNKA 1047 L+ LQ D +IH W+L+ R + F + Q GFYS+ ++ Q L + + Sbjct: 1028 LWLQLQTDDKLPDVIIHSWTLQERTN-------FQQQQNLGFYSLLWLTQAL----SSSS 1076 Query: 1048 VRIAVVTDEVFPVTGQETLHPENAPLIGLGIVIPQE-----MQHIRHLTVDIQAASAANX 1102 + I V+T +V V G E L+P++A ++GL VIPQE QHI DI Sbjct: 1077 LSIYVLTQQVQNVLGNENLNPDDATILGLVKVIPQEYPNLTCQHIDVSISDINFQQLVRE 1136 Query: 1103 XXXXXXXXXXXXXXXXXHRDRQVSYRGLQRWVPIYQPIKLEPQIVKPDLFRTNGVYVLTG 1162 R V+YRG RW+ +QPI L P+ + L T GVYV+ G Sbjct: 1137 INIPPVLSDTLPLEKGGLR-MSVAYRGKTRWIQEFQPISL-PEPTQLPLI-TGGVYVIAG 1193 Query: 1163 G-AGMIGWIIAEHLAINYRASIAIIQRS-FPVRPEWDKWLGDHPEDDSTSRTIQEMIQAE 1220 +G I A+ LA A + + RS P EWD WL H D+ S IQ++ + Sbjct: 1194 DLVEGLGLIYAKFLAATVNAKLVFLGRSDLPQPKEWDNWLATHGRQDAVSHCIQQLQGLQ 1253 Query: 1221 KLGANIAIYPADVSDYGQMADAIGAIECELGAINGVIHCAANMGAEFFNPVTRLDEALCR 1280 G D+++ Q+ DAI G INGVIH A MG + L C Sbjct: 1254 AQGCEFLFTTVDLAEISQVEDAIAQALTRFGKINGVIH-AGVMGDRASCLIRNLTIPECE 1312 Query: 1281 TIFQPKXXXXXXXXXXXXXXXXXXXXXMSSTAAVLXXXXXXXXXXXXVFMDTYMKIRNKH 1340 F K SS +AV+ FMD R ++ Sbjct: 1313 KQFHTKIHGLLALETALKNQPLDFFLLQSSLSAVVGGIGFAAYAGANCFMDAIAHQRTQN 1372 Query: 1341 RQVKWKTVDXXXXXXXXXXXXGYTSSIGDLAMSPEEGIEALTRVLSAERYHHMVHSPGIL 1400 W +++ + I DLAM+ +E + R+L+ + SP Sbjct: 1373 SNTHWISINWDAVSLAEITTSTGATLI-DLAMTSQEVWQVTERILAQPIAAQITVSP--- 1428 Query: 1401 DKRLAEWVQLQGISEGKPVQPRDGQKKRQRPAAMVEYEKPSNHLEKQIAGIWEEFLGIRD 1460 V L + +P++ RP Y PSN +E ++ + E LGI Sbjct: 1429 -------VDLASRQQSQPLE--QSTTNHARPQITATYLPPSNEIEARVTQVMESLLGIAP 1479 Query: 1461 ISIHDNFFELGATSLTLIRIKSIVEETLSLQIPIVD-LFANPTIAALAKRIGQIEN 1515 I ++DNFFELG SL I+ S + E +++P+ LF +PTI +AK I IEN Sbjct: 1480 IGVNDNFFELGGHSLLAIQAVSQLREEFQVELPMRQFLFESPTIGGIAKII--IEN 1533 >all2646 [Q] COG3321 Polyketide synthase modules and related proteins Length = 1488 Score = 932 bits (2410), Expect = 0.0, Method: Compositional matrix adjust. Identities = 542/1517 (35%), Positives = 829/1517 (54%), Gaps = 105/1517 (6%) Query: 7 GLEIAVIGMSARVPGAADVHTFWDNLVNGKESITFFTADELLESGIEPAAVSHPDYVRAK 66 GLEIA+IG++ + PGA ++ +W NL NG ESIT T +++ ++G++P + HP+YV+ + Sbjct: 6 GLEIAIIGINGKFPGANNLEEYWQNLRNGVESITNLTDEQIQKNGVDPTQLKHPNYVKRQ 65 Query: 67 GYLENSDQFDASFFNYSPLEAEVMDPQVRIFHECVWEALEDAGYCPGTYPGLIGXXXXXX 126 ++N + FDA FF ++P EAE++DPQ R+F EC W ALEDAGY P Y G IG Sbjct: 66 AIIDNIEYFDAEFFGFNPREAEILDPQHRLFLECAWTALEDAGYNPENYTGAIGVYAGAA 125 Query: 127 ASLYWQALSYLSEGARLLGPFTANQFA--------NKDYMSTLISHRLNLKGPSLTVNTA 178 + Y L + P NQ + +KD+++T +S++LNL+GPSL + TA Sbjct: 126 MNNYLLNL--------ITNPQIQNQISRYQLFLSNDKDFLTTRVSYKLNLRGPSLDIQTA 177 Query: 179 CSTSLVTIHLAAQALLNGECDIALAGGASITLPLKSGYQYQEGMILSPDGHCKAFDEEGQ 238 CSTSLV +H+A Q+LL+GECDIALAGG S L +GY YQEG I SPDGHC+AFD + Q Sbjct: 178 CSTSLVAVHVACQSLLSGECDIALAGGVS--LAKATGYLYQEGGIYSPDGHCRAFDADAQ 235 Query: 239 GSVPGNGAGVVVLKRFEEAVQDGDHIYAVIKGSAINNDGNRKSAYTAPSVEGQVEVIQTA 298 G++ G+G G+VVLKR +EA++D D+I+AVIKGSAINNDG K +YTAP ++ Q VI+ A Sbjct: 236 GTIAGSGLGIVVLKRLQEAIEDRDYIHAVIKGSAINNDGGLKVSYTAPRIDTQAAVIRAA 295 Query: 299 QQLAEVNAASIQFVETHGTGTVLGDPIELEALKAAF---GNSEGVCRIGSVKSNIGHLDA 355 Q LA V A I ++ETHGTGT LGDPIE+ AL AF G C I SVK+NIGHLDA Sbjct: 296 QALAGVEPADISYIETHGTGTALGDPIEIAALTQAFRAGTEKTGFCAISSVKTNIGHLDA 355 Query: 356 AAGVAGFIKATLSLQHRLLPPTLHFTTLNPKINLADSPFVVNGKLSDLSGEGNPLRAGVS 415 AAG+A IK L+L+H+ +PP LHF NP+I+ + +PF VN L D + P RAGVS Sbjct: 356 AAGIASLIKTVLALKHQQIPPNLHFQQPNPQIDFSQTPFYVNTNLVDWETDKTPRRAGVS 415 Query: 416 SFGIGGTNAHIVLEEAXXXXXXXXGR---DSQLILISAKSRSALEQHSSNLAAYIRNHPE 472 SFGIGGTNAH++LEEA + + Q++ +SAKS ALE+ + NLA Y++ HP+ Sbjct: 416 SFGIGGTNAHVILEEAPIKFKIQNSKFKINYQMLCLSAKSEKALEEATINLATYLQQHPQ 475 Query: 473 VPLADLAYTLQVGRTDFEHRRFVVANHTGELPEMLQPLGNEKGKPSRKVFTSTVEQENKP 532 LAD+AYTL +GR F +RR V+ T E ++L+ +T T +++ Sbjct: 476 FNLADIAYTLHIGRQHFAYRRMVLCQTTEEAAQILE---------KETKYTHTNSEKSPS 526 Query: 533 IVFMFPGLGNQYVDMGLGLYRTELLFKQELDRCFDLLDSHLDFSMKAILFPQEARDEAVY 592 I FMFPG G+ Y++MG LY TE +F++++D C +LL L + +ILF E+ Sbjct: 527 IAFMFPGQGSHYLNMGKELYETEAIFREQIDHCCELLQHDLGLDLLSILFETESIPSPQS 586 Query: 593 KINRIDIN----QMVVFIFEYALGKYLMELGIKPKYMIGYSFGEFAAACLAGVFVLEDAI 648 + Q +FI EYAL K + GI+P+ MIG+S GE+ A LAGVF L D + Sbjct: 587 PVPSPQSQTIYAQPALFIIEYALAKLWISWGIQPQAMIGHSLGEYVVATLAGVFSLPDVL 646 Query: 649 RVIIRRGQMIKGTEEGAMLSVPMTEQELRPLLPPDVSLSIVNGPS-CVVGGTRTAVEQFE 707 +++ RG++++ GAMLSV M+ +L+PLL ++ ++ N P CVV GT + Q E Sbjct: 647 KLVALRGRLMQQCPTGAMLSVGMSAAKLQPLLTDNLVIAAYNAPELCVVSGTEAEIVQLE 706 Query: 708 EQLKSLRQICIRLDTSYALHSAVMEPVRDAFAEEMKQIRLYPPQIPFISNLSGNWITDEE 767 L RL TS+A HS +ME + F ++I L P+IPFISN++G WIT E+ Sbjct: 707 TNLNKQGISNRRLQTSHAFHSPLMESMITPFIAAFQKITLQTPKIPFISNVTGTWITAEQ 766 Query: 768 ATDPGYWGQQLTDSIRFADGLKEILKEEALTFLEVGPDRNLSALLRYFVHRDSSHTILNL 827 ATDP YW L ++FA G+KE+L E LEVG R L+ L + + +SHTIL+ Sbjct: 767 ATDPHYWVNHLRQPVQFATGIKELLTEPQQILLEVGAGRTLATLAK---QQTNSHTILSS 823 Query: 828 IRNPQENVEDQTYLYTRLGQLWGAGHSIEWMKLYAYERRNRLSLPAYPFERESYGMEGNP 887 +R+PQ+ D +L LGQLW AG SI+W Y +++R RL LP YPF+R+ Y + Sbjct: 824 LRHPQDTQSDVAFLLQTLGQLWLAGVSIDWENFYTHQQRQRLPLPTYPFQRQRYWI---- 879 Query: 888 FDMLEGQQKGKHSLLPKQPHMEDWFYLPLWQQKALPLASGPLG-GQLC-LLFANDDLISR 945 D+ G+Q ++ P+ YLP W +++LP + +LC L+F ++ I + Sbjct: 880 -DLKAGEQGSENIPSPR-------LYLPSW-ERSLPHPQVDIAEKRLCWLVFTDNYGIYQ 930 Query: 946 ELLQALRSSGQRVIPVYRGHEFSMHDDGEYTIHPESLADYQQLFAVLQEKQVEADNLIHL 1005 E++ L++ G VI V +G ++ +T++P++ D+ +L++ L+ +++ ++++L Sbjct: 931 EIINTLQAVGHDVIIVSQGEKYDQPAYRTFTVNPQNSQDFVELWSDLELRELIPHHILYL 990 Query: 1006 WSLENRVSAPLDAAAFHESQKNGFYSVTYIVQCLHQFSRNKAVRIAVVTDEVFPVTGQET 1065 W L + PL S+ Y+ Q + S + + + +VT++ + G E Sbjct: 991 WDLTDLQQQPL--------------SLLYLAQAISSQSIEREITLTLVTNDGQLLLGNEN 1036 Query: 1066 LHPENAPLIGLGIVIPQEMQHIRHLTVDIQAASAANXXXXXXXXXXXXXXXXXXHRDRQV 1125 + P A + G+G VI QE+ + VDI ++ A+ D V Sbjct: 1037 IQPMKATVWGMGKVISQEIPQLTCRCVDISLSTVAS--TNEQIAQQLITECLNNQNDSVV 1094 Query: 1126 SYRGLQRWVPIYQPIKLEPQIVKPDLFRTNGVYVLTGGAGM-IGWIIAEHLAINYRASIA 1184 +YRG RW IY+P+ ++ K + G YV+ G +G + AE L N S+ Sbjct: 1095 AYRGNYRWNQIYKPLLMDDAQSKISVHE-GGNYVILGDLTTGLGTVFAEFLMKN---SVR 1150 Query: 1185 IIQRSFPVRPEWDKWLGDHPEDDSTSRTIQEMIQAEKLGANIAIYPADVSDYGQMADAIG 1244 ++ S D + T+++ + + +G + D++ ++ +AI Sbjct: 1151 LVLLS-----------------DVITETLKQSL--DNVGIDYLSLNIDITKQAELENAIA 1191 Query: 1245 AIECELGAINGVIHCAANMGAEFFNPVTRLDEALCRTIFQPKXXXXXXXXXXXXXXXXXX 1304 E + G INGV + + +L ++ K Sbjct: 1192 QAETKFGQINGVFYSTPMSNEHSMAFLPQLTTKHWEYNYRTKIQGLCVLAEVLRDKPLDF 1251 Query: 1305 XXXMSSTAAVLXXXXXXXXXXXXVFMDTYMKIRNKHRQVKWKTV--DXXXXXXXXXXXXG 1362 SS + VL +D + +N++ + W ++ D Sbjct: 1252 CVLQSSLSTVLGGLGLAVYAAANAVIDMFAIQQNQNSKFPWISINWDACRSDLETDINHS 1311 Query: 1363 YTSSIGDLAMSPEEGIEALTRVLSAERYHHMVHSPGILDKRLAEWVQLQGISEGKPVQPR 1422 + +++ LA++P E ++ ++ +V + LDKRL +WV P + + Sbjct: 1312 FAANLVTLALTPAEVWQSTQHIIKLGLPESVVVTKSDLDKRLEKWV------TNTPTKTK 1365 Query: 1423 -DGQKKRQRPAAMVEYEKPSNHLEKQIAGIWEEFLGIRDISIHDNFFELGATSLTLIRIK 1481 + RP EY P + +E IA IW++ LGI I I+D+FF+LG SL I+ Sbjct: 1366 TETNNSYTRPQLTNEYIAPRDEIETAIAQIWQDLLGISPIGINDSFFDLGGHSLLAIQAI 1425 Query: 1482 SIVEETLSLQIPIVDLF 1498 S + + +++ + +L Sbjct: 1426 SRLRDRFGVELSMRNLL 1442 >AGl2329 [Q] COG3321 Polyketide synthase modules and related proteins Length = 211 Score = 714 bits (1842), Expect = 0.0, Method: Compositional matrix adjust. Identities = 0/1524 (0%), Positives = 0/1524 (0%), Gaps = 91/1524 (5%) Query: 10 IAVIGMSARVPGAADVHTFWDNLVNGKESITFFTADELLESGIEPAAVSHPDYVRAKGYL 69 +S A + + A + R Sbjct: 40 AQATDVSVNKATAKLYPVANTPAAMLELGVEGVKTYIKTIGLYNSKAENIIKTCRILLEQ 99 Query: 70 ENSDQFDASFFNYSPLEAEVMDPQVRIFHECVWEALEDAGYCPGTYPGLIGXXXXXXASL 129 N + + + V + W + + + Sbjct: 100 HNGEVPEDRAALEALPGVGRKTANVVLNTAFGWPTIAVDTHIFRVCNRTQFAPGKNVEQV 159 Query: 130 YWQALSYLSEGARLLGPFTANQFANKDYMSTLISHRLNLKGPSLTVNTACSTSLVTIHLA 189 Sbjct: 160 219 Query: 190 AQALLNGECDIALAGGASITLPLKSGYQYQEGMILSPDGHCKAFDEEGQGSVPGNGAGVV 249 Sbjct: 220 279 Query: 250 VLKRFEEAVQDGDHIYAVIKGSAINNDGNRKSAYTAPSVEGQVEVIQTAQQLAEVNAASI 309 Sbjct: 280 339 Query: 310 QFVETHGTGTVLGDPIELEALKAAFGNS---EG-VCRIGSVKSNIGHLDAAAGVAGFIKA 365 Sbjct: 340 399 Query: 366 TLSLQHRLLPPTLHFTTLNPKINLADSPFVVNGKLSDLSGEGN-PLRAGVSSFGIGGTNA 424 Sbjct: 400 459 Query: 425 HIVLEEAXXXXXXXXGRDSQLIL----ISAKSRSALEQHSSNLAAYIRNHPEVPLADLAY 480 Sbjct: 460 519 Query: 481 TLQVGRTDFEHRRFVVANHTGELPEMLQPLGNEKGKPSRKVFTSTVEQENKPIVFMFPGL 540 Sbjct: 520 ------ 573 Query: 541 GNQYVDMGLGLYRTELLFKQELDRCFDLLDSHLDFSMKAILFPQEARDEAVYKINRIDIN 600 Sbjct: 574 ---- 629 Query: 601 QMVVFIFEYALGKYLMELGIKPKYMIGYSFGEFAAACLAGVFVLEDAIRVIIRRGQMIKG 660 Sbjct: 630 689 Query: 661 TEEGAMLSVPMTEQELRPLLPPDVSLSIVNGP-SCVVGGTRTAVEQFEEQLKSLRQICIR 719 Sbjct: 690 749 Query: 720 LDTSYALHSAVMEPVRDAFAEEMKQIRLYPPQIPFISNLSGNWITDEEATDPGYWGQQLT 779 Sbjct: 750 809 Query: 780 DSIRFADGLKEILKEEALTFLEVGPDRNLSALLRYFVHRDSSHTILNLIRNPQENVEDQT 839 Sbjct: 810 -- 867 Query: 840 YLYTRLGQLWGAGHSIEWMKLYAYERRNRLSLPAYPFERESYGMEGNPFDMLEGQQKGKH 899 Sbjct: 868 - 926 Query: 900 SLLPKQPHMEDWFYLPLWQQKALPLASGPLGGQLCLLFANDDLISRELLQALRSSGQRVI 959 Sbjct: 927 ------------- 973 Query: 960 PVYRGHEFSMHDDGEYTIHPESLADYQQLFAVLQEKQVEADNLIHLWSLENRVSAPLDAA 1019 Sbjct: 974 -- 1031 Query: 1020 AFHESQKNGFYS------VTYIVQCLHQFSRNKAVRIAVVTDEVFPVTGQETLHPENAPL 1073 Sbjct: 1032 ------------------ 1073 Query: 1074 IGLGIVIPQEMQHIRHLTVDIQA---ASAANXXXXXXXXXXXXXXXXXXHRDRQVSYRGL 1130 Sbjct: 1074 1133 Query: 1131 QRWVPIYQPIKLEPQIVKPDLFRTNGVYVLTGGAGMIGWIIAEHLAINYRASIAIIQRS- 1189 Sbjct: 1134 -------- 1185 Query: 1190 FPVRPEWDKWLGDHPEDDSTSRTIQEMIQAEKLGANIAIYPADVSDYGQMADAIGAIECE 1249 Sbjct: 1186 1245 Query: 1250 LGAINGVIHCAANMGAEFFNPVT--RLDEALCRTIFQPKXXXXXXXXXXXXXXXXXXXXX 1307 Sbjct: 1246 ---- 1301 Query: 1308 MSSTAAVLXXXXXXXXXXXXVFMDTYMKIRNKHRQVKWKTVDXXXXXXXXXXXXGYTSSI 1367 Sbjct: 1302 - 1360 Query: 1368 GDLAMSPEEGIEALTRVLSAERYHHMVHSPGILDKRLAEWVQLQGISEGKPVQPRDGQKK 1427 Sbjct: 1361 --------- 1411 Query: 1428 RQRPAAMVEYEKPSNHLEKQIAGIWEEFLGIRDISIHDNFFELGATSLTLIRIKSIVEET 1487 Sbjct: 1412 1471 Query: 1488 LSLQIPI-VDLFANPTIAALAKRI 1510 Sbjct: 1472 1495 >AGl2313 [Q] COG3321 Polyketide synthase modules and related proteins Length = 211 Score = 699 bits (1804), Expect = 0.0, Method: Compositional matrix adjust. Identities = 0/1284 (0%), Positives = 0/1284 (0%), Gaps = 88/1284 (6%) Query: 2 SKQTNGLEIAVIGMSARVPGAADVHTFWDNLVNGKESITFFTADELLESGIEPAAVSHPD 61 + + N + ++ + A + A L + Sbjct: 21 TTELNFSSPFELLIAVLLSAQATDVSVNKATAKLYPVANTPAAMLELGVEGVKTYIKTIG 80 Query: 62 YVRAKGYLENSDQFDASFFNYSPLEAEVMDPQVRIFHECVWEALEDAGYCPGTYPGLIGX 121 +K + + + + + + Sbjct: 81 LYNSKAENIIKTCRILLEQHNGEVPEDRAALEALPGVGRKTANVVLNTAFGWPTIAVDTH 140 Query: 122 XXXXXASLYWQALSYLSEGARLLGPFTANQFANKDYMSTLISHRLNLKGPSLTVNTACST 181 + + + L +F + ++ R + Sbjct: 141 IFRVCNRTQFAPGKNVEQVEEKLLKVVPAEFKVDCHHWLILHGRYTCIARKPRCGSCIIE 200 Query: 182 SLVTIHLAAQALLNGECDIALAGGASITLPLKSGYQYQEGMILSPDGHCKAFDEEGQGSV 241 Sbjct: 201 -- 258 Query: 242 PGNGAGVVVLKRFEEAVQDGDHIYAVIKGSAINNDGNRKSAYTAPSVEGQVEVIQTAQQL 301 Sbjct: 259 318 Query: 302 AEVNAASIQFVETHGTGTVLGDPIELEALKAAFGNS---EGVCRIGSVKSNIGHLDAAAG 358 Sbjct: 319 378 Query: 359 VAGFIKATLSLQHRLLPPTLHFTTLNPKINLADSPFVVNGKLSDLSGEGNPLRAGVSSFG 418 Sbjct: 379 438 Query: 419 IGGTNAHIVLEEAXXXXXXXXGRD---SQLILISAKSRSALEQHSSNLAAYIRNHPEVPL 475 Sbjct: 439 498 Query: 476 ADLAYTLQVGRTDFEHRRFVVANHTGELPEMLQPLGNEKGKPSRKVFTSTVEQENKPIVF 535 Sbjct: 499 --------- 549 Query: 536 MFPGLGNQYVDMGLGLYRTELLFKQELDRCFDLLDSHLDFSMKAILFPQEARDEAVYKIN 595 Sbjct: 550 ------ 603 Query: 596 RIDINQMVVFIFEYALGKYLMELGIKPKYMIGYSFGEFAAACLAGVFVLEDAIRVIIRRG 655 Sbjct: 604 663 Query: 656 QMIKGTEEGAMLSVPMTEQELRPLLPPDVSLSIVNGPS-CVVGGTRTAVEQFEEQLKSLR 714 Sbjct: 664 723 Query: 715 QICIRLDTSYALHSAVMEPVRDAFAEEMKQIRLYPPQIPFISNLSGNWITDEEATDPGYW 774 Sbjct: 724 783 Query: 775 GQQLTDSIRFADGLKEILKEEALTFLEVGPDRNLSALLRYFVHRDSSHTILNLIRNPQEN 834 Sbjct: 784 -- 841 Query: 835 VEDQTYLYTRLGQLWGAGHSIEWMKLYAYERRNRLSLPAYPFERESYGMEGNPFDMLEGQ 894 Sbjct: 842 ------------ 889 Query: 895 QKGKHSLLPKQPHMEDWFYLPLWQQKALPLASGPLGGQLCLLFANDDLISRELLQALRSS 954 Sbjct: 890 -- 947 Query: 955 GQRVIPVYRGHEFSMHDDGEYTIHPESLADYQQLFAVLQEKQVEADNLIHLWSLENRVSA 1014 Sbjct: 948 ----- 1002 Query: 1015 PLDAAAFHESQKNGFYSVTYIVQCLHQFSRNKAVRIAVVTDEVFPVTGQETLHPENAPLI 1074 Sbjct: 1003 ---------- 1052 Query: 1075 GLGIVIPQEMQHIRHLTVDIQAASAANXXXXXXXXXXXXXXXXXXHRDRQVSYRGLQRWV 1134 Sbjct: 1053 ----- 1107 Query: 1135 PIYQPIKL-EPQIVKPDLFRTNGVYVLTGG-AGMIGWIIAEHLAINYRASIAIIQRSFPV 1192 Sbjct: 1108 ----- 1162 Query: 1193 RPEWDKWLGDHPEDDSTSRTIQEMIQAEKLGANIAIYPADVSDYGQMADAIGAIECELGA 1252 Sbjct: 1163 --------------------- 1201 Query: 1253 INGVIHCAANMGAEFFNPVTRLDE 1276 Sbjct: 1202 1225 Score = 68.9 bits (167), Expect = 7e-11, Method: Compositional matrix adjust. Identities = 0/84 (0%), Positives = 0/84 (0%), Gaps = 1/84 (1%) Query: 1428 RQRPAAMVEYEKPSNHLEKQIAGIWEEFLGIRDISIHDNFFELGATSLTLIRIKSIVEET 1487 Sbjct: 1368 1427 Query: 1488 LSLQIPIVD-LFANPTIAALAKRI 1510 Sbjct: 1428 1451 >ML2353_1 [Q] COG3321 Polyketide synthase modules and related proteins Length = 1031 Score = 622 bits (1605), Expect = e-177, Method: Compositional matrix adjust. Identities = 354/905 (39%), Positives = 513/905 (56%), Gaps = 43/905 (4%) Query: 10 IAVIGMSARVPGAADVHTFWDNLVNGKESITFFTADELLESGIEPAAVSHPDYVRAKGYL 69 IAV+GM+ + PGA DV FW NL GKESI + EL ++G+ A++ P YVR L Sbjct: 8 IAVVGMAGKFPGANDVSAFWTNLRRGKESIVTLSEQELRDNGVSDKALADPAYVRRAPLL 67 Query: 70 ENSDQFDASFFNYSPLEAEVMDPQVRIFHECVWEALEDAGYCPGTYPGLIGXXXXXXASL 129 + D+FDA FF PL A+V+DPQ R+F +C W ALEDAG P + G IG S Sbjct: 68 DGIDEFDADFFGLPPLAAQVLDPQHRLFLQCAWHALEDAGCDPAQFDGSIGVYGTSSPSG 127 Query: 130 YW--QALSYLSEGARLLGPFTANQFA-----NKDYMSTLISHRLNLKGPSLTVNTACSTS 182 Y LS+ L +QF+ +KD+++T ISH NL+GPS+ V TACS+S Sbjct: 128 YLLHNLLSHRDPHTVLAEGLNFDQFSLFLQNDKDFLATRISHAFNLRGPSIAVQTACSSS 187 Query: 183 LVTIHLAAQALLNGECDIALAGGASITLPLKSGYQYQEGMILSPDGHCKAFDEEGQGSVP 242 LV +HLA +LL+GECD+ALAGG+S+ +P + GY + G ++S GHC+ FD G+V Sbjct: 188 LVALHLACLSLLSGECDMALAGGSSLCIPHRVGYWHSPGSMVSAVGHCRPFDVRADGTVF 247 Query: 243 GNGAGVVVLKRFEEAVQDGDHIYAVIKGSAINNDGNRKSAYTAPSVEGQVEVIQTAQQLA 302 G+G +V LK + A+ D I+AVI GSAINNDG+ K Y AP+ Q +VI A +A Sbjct: 248 GSGVALVALKPLQAAIDASDRIHAVILGSAINNDGSMKMGYAAPNPAAQADVIAEAHAVA 307 Query: 303 EVNAASIQFVETHGTGTVLGDPIELEALKAAFGNSE----GVCRIGSVKSNIGHLDAAAG 358 ++++++ +VETHGTGT LGDPIE++ LK AF S+ G C +GSVKSNIGHL+ AAG Sbjct: 308 GIDSSTVSYVETHGTGTPLGDPIEIQGLKTAFEVSQIPRPGPCVLGSVKSNIGHLEVAAG 367 Query: 359 VAGFIKATLSLQHRLLPPTLHFTTLNPKINLADSPFVVNGKLSDLSGEGNPLRAGVSSFG 418 +AG IK L L+++ +P TLH+T+ N ++ L +PFVV +G RAGVSSFG Sbjct: 368 IAGLIKTILCLKNKAIPATLHYTSPNRELRLDQTPFVVQSNYGPWKWDGV-RRAGVSSFG 426 Query: 419 IGGTNAHIVLEEAXXXXXXXXGRDS-QLILISAKSRSALEQHSSNLAAYIRNHPEVPLAD 477 +GGTN H+VLEEA Q+IL+SA++ +AL + LA + L+D Sbjct: 427 VGGTNVHVVLEEASVEASTVAASTGPQVILLSAQTAAALGESREALATVLEKPGAPDLSD 486 Query: 478 LAYTLQVGRT----------DFEHRRFVV--ANHTGELPEMLQPLGNEKGKPSRKVFTST 525 +AYTL R D EH V+ A H +G R S Sbjct: 487 VAYTLAGRRKHNITMAAVVRDREHAVTVLRAAEHDNVF------VGESGADTGRSAAASI 540 Query: 526 VEQENKPIVFMFPGLGNQYVDMGLGLYRTELLFKQELDRC-FDLLDSHLDFSMKAILFPQ 584 + +VF+FPG G Q+V M GLY TE +F + D C ++ D + + +F Sbjct: 541 TTLGSDRVVFLFPGQGAQHVGMAKGLYDTESVFAEHFDTCSAGFREAMDDLDLHSAIFNG 600 Query: 585 EARDEAVYKINRIDINQMVVFIFEYALGKYLMELGIKPKYMIGYSFGEFAAACLAGVFVL 644 A D + RID +Q +F EYAL K + G+ IGYS GE+ AA LAGVF L Sbjct: 601 TAID-----LERIDRSQPALFTVEYALAKLVESFGVGAGAYIGYSTGEYIAATLAGVFDL 655 Query: 645 EDAIRVIIRRGQMIKGTEEGAMLSVPMTEQELRPLL----PPDVSLSIVNGP-SCVVGGT 699 E AI+ + R +++ + GAM++V + +++ L V LS VN P +CVV G Sbjct: 656 ETAIKTVSLRARLMHESPPGAMVAVALGPEDITEYLAEYSAKGVELSAVNDPGNCVVAGP 715 Query: 700 RTAVEQFEEQLKSLRQICIRLDTSYALHSAVMEPVRDAFAEEMKQIRLYPPQIPFISNLS 759 + + F ++L + R+ ++A H++ MEP+ F+E + + +L P P +SNL+ Sbjct: 716 KDQIRAFSQRLDEVGIPVRRVRATHAFHTSSMEPMLREFSEFLSRQQLRVPNTPLLSNLT 775 Query: 760 GNWITDEEATDPGYWGQQLTDSIRFADGLKEILKEEALTFLEVGPDRNLSALLRYFVHRD 819 G W+++++ TDP W +Q++ +IRFAD L +L + +EVGP +L+ Sbjct: 776 GTWMSEQQVTDPENWTRQISSTIRFADELDVVLSQSGRVLVEVGPGGSLTGSAMRHPRWS 835 Query: 820 SSHTILNLIRNPQENVEDQTYLYTRLGQLWGAGHSIEWMKLYAYERRNRLSLPAYPFERE 879 S H + L+R+P +NV+D LG+LW AG ++W + + +SLP YPF R+ Sbjct: 836 SGHRAVRLMRHPLQNVDDHDTFLRALGELWSAGIEVDWAPQRSV-MPHLVSLPGYPFARQ 894 Query: 880 SYGME 884 + +E Sbjct: 895 RHWVE 899 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.319 0.136 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 110,585,066 Number of extensions: 4669870 Number of successful extensions: 11317 Number of sequences better than 1.0e-05: 143 Number of HSP's gapped: 10788 Number of HSP's successfully gapped: 155 Length of query: 1551 Length of database: 38,378,431 Length adjustment: 120 Effective length of query: 1431 Effective length of database: 24,538,351 Effective search space: 35114380281 Effective search space used: 35114380281 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 123 (52.0 bits)