BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0489.0028.p (2184 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value all2635 [Q] COG3321 Polyketide synthase modules and related prot... 716 0.0 all2646 [Q] COG3321 Polyketide synthase modules and related prot... 691 0.0 AGl2313 [Q] COG3321 Polyketide synthase modules and related prot... 559 e-158 AGl2329 [Q] COG3321 Polyketide synthase modules and related prot... 460 e-128 ML2353_1 [Q] COG3321 Polyketide synthase modules and related pro... 457 e-127 >all2635 [Q] COG3321 Polyketide synthase modules and related proteins Length = 1565 Score = 716 bits (1847), Expect = 0.0, Method: Compositional matrix adjust. Identities = 469/1368 (34%), Positives = 674/1368 (49%), Gaps = 149/1368 (10%) Query: 10 EVAIIGMSGSFPGAKNLEQFFQNVKNGVDSISFFTDEQLAEAGVPAEVYTKENFVKAKGY 69 EVAI+GM+G FPGAKN+++F+ N+KNG++SI F ++E L GV AE K+N+V+A Sbjct: 38 EVAIVGMAGRFPGAKNVDEFWDNLKNGINSIKFLSNEDLLANGVKAEDLEKQNYVRAYAS 97 Query: 70 LNECEYFDNSFFGYTPNEAQFMDPQTRLLHEHAWMALEDAGYPPGRTQDAIGVYAGGRPH 129 L + FD FFGY+P EA+ +DPQ RL E AW ALE+AGY + I VY G + Sbjct: 98 LAGIDEFDAGFFGYSPREAEILDPQHRLFLECAWEALENAGYDSEQYSGNIAVYGGAALN 157 Query: 130 FHWEALSLSMGSRNGTEDFEIAHLNDKDLMSTRVSYKLNLKGPSYTLFTACSTSLVAVHA 189 + L+ + R ++ ++ N LM TRVSYKLNL G S + T CSTSLV+VH Sbjct: 158 SYLVNLASNSNYRENSDRTQVVISNVMGLMPTRVSYKLNLTGASCGIQTGCSTSLVSVHI 217 Query: 190 ACQGVISGECDMAVAGGVSVTSPLQNGYFHQDGMILSSDGRCRAFDAASDGTVVGNGIGL 249 ACQ +++ ECD+A+AGGVS+ + GY +Q+ +LS DG CRAFD + GTV GNG+G+ Sbjct: 218 ACQSLLNKECDIALAGGVSIGIGEKAGYLYQEDGVLSPDGYCRAFDVNAKGTVFGNGVGI 277 Query: 250 VILKRLEDALDDNDHIYAVIKGTAINNDGSRKVGYSAPSVDGQAEVIRTAHRVAGVDPKE 309 V+LKRL DA+ D DHIYA+IK TAINNDGS+KVG +APSV GQA+ I TA A ++P+ Sbjct: 278 VVLKRLRDAIQDGDHIYAIIKATAINNDGSQKVGLTAPSVTGQAKAITTALTKAKINPET 337 Query: 310 IGYIEAHGTGTALGDPIEVKALTTAF--QTKRKHFCGLGSVKTNIGHLDSAAGIAGLIKA 367 I YIE HGTGTALGDPIE+ ALT AF T +K FC +GSVKTNIGHLD+AAGI+GLIK Sbjct: 338 IQYIETHGTGTALGDPIEIAALTKAFSPHTHQKQFCAVGSVKTNIGHLDAAAGISGLIKT 397 Query: 368 VLALHNKCLLPTLHFANPNPHLMLEDSPFYLVDRMREWENGSGPRRAGVSSFGVGGTNAH 427 LAL +K + P+L+F NP + +SPF++ ++ W N PRRAGVSSFG+GGTNAH Sbjct: 398 ALALKHKQIPPSLNFTAANPQIDFANSPFFVNTQLTPWINHQHPRRAGVSSFGMGGTNAH 457 Query: 428 IVLEEAPSGQSVKQAEAQ--EQLLVFSAKTREALEQSIEAFVQDVQKNPGKASADIAYTL 485 +LEEAP+ ++ ++ + LL SAK+ +ALEQ+ +QK+P AD+AYTL Sbjct: 458 AILEEAPTQFKIQNSKFKINYHLLCLSAKSEKALEQATINLATHLQKHPELNLADVAYTL 517 Query: 486 QQGREHFSYRQYVSCRTLLAGCAALR-VKADQALWVDPKKELKPVYFWFAGMA------- 537 Q GR F++R+ + C+T L V A Q L P+ + F F G Sbjct: 518 QIGRRAFNHRRCLVCQTPAQAIEILTGVDASQLLSYSPENTEPSIVFMFPGQGSQYLNMG 577 Query: 538 ---------LEEAVQHYHSCLHHPYCREEMEELLLQASGIRG---------------VKR 573 + + H L P+ ++ +L + + Sbjct: 578 QELYNTEPVFRKEIDHCSELL-QPHLGCDLPSILFKQDNENSPSPQSPVPNLNYELRITN 636 Query: 574 DELLSGGSDVYIGQTPVFLFQLALAKWLLRVGVKPAALMGTGTGAYVAGCLAGVFTLEEA 633 ELL + Q +F + ALAK L G++P A++G G YVA LAGVFTL +A Sbjct: 637 YELL---TQTTYAQPALFAVEYALAKLWLSYGIQPQAMIGHSIGEYVAATLAGVFTLADA 693 Query: 634 LMLMEKRDRLLEEW------------------------------------RGSEGDLFLL 657 L ++ +R +L+++ G+E + LL Sbjct: 694 LAIVAQRGKLMQQCPSGVMLSVSLAPEKLQPFLTDDLVIAVHNAPELCVVSGTEAAITLL 753 Query: 658 EALQSE-------------------------FYEAFDSVTLSAPAIPLLSADAGS-NTVL 691 E L + + +++L P IP +S G+ T Sbjct: 754 EKLLTHQNITHRRLHTSHAFHSPLMETAVTPLTQILQNISLHPPQIPFISNVTGTWITPE 813 Query: 692 DVTLPDYWVNALGADDDGKSLPAKAEEADKHLVLHFGAA------------GEPSGPSG- 738 T P+YW L + ++ + + G P+ SG Sbjct: 814 QATNPNYWATHLRQPVLFAEGITELQQTPNQIFVEVGFGQTLSTFVRQFPDAPPTLSSGR 873 Query: 739 YISLVKSGPELL-ETVGCIWANGYPLQWDELAKHQNRARVILPTYPFTRKRYWVDTQQIK 797 + +S L+ +T+G +W G + W EL Q R R+ LPTYPF R+RYWV+ + Sbjct: 874 HPQDTQSDVALICKTLGQLWLRGVTINWSELYTQQQRRRLPLPTYPFERQRYWVERDTLP 933 Query: 798 Q-FQNIWKRQEPQPGKENKEEWMYVPSWIRSEYMPEEREQQQGLIAVFATQEPFVARCIE 856 + N K + Q E W Y+PSW + + + VF R ++ Sbjct: 934 ETTSNTSKTLQKQ---EQISNWFYLPSWRQKPLLRSAAPLNKQRYLVFCHAGNAGERLVQ 990 Query: 857 RLEQMGHTIARIEAGESFQQNNLSFEINPEXXXXXXXXXXXXXXXGDGPVRIVHFWCMHP 916 L++ G + ++ GE F Q ++ I P P I+H W + Sbjct: 991 HLQETGQEVVTVKPGEGFTQEGDNYAIAPHNPEDYKTLWLQLQTDDKLPDVIIHSWTLQE 1050 Query: 917 QSAAREQLPEAEECNRLGYYTLLNIARAVSQLQLQQPVTIDIVANQVAEVTGNETVVPAK 976 ++ ++Q LG+Y+LL + +A+S L +I ++ QV V GNE + P Sbjct: 1051 RTNFQQQ-------QNLGFYSLLWLTQALSSSSL----SIYVLTQQVQNVLGNENLNPDD 1099 Query: 977 ATLFGPLRVIPKEYENIACRLIDTDQYDHHI--LCRILSGP---------ENNRRADWIA 1025 AT+ G ++VIP+EY N+ C+ ID D + L R ++ P E +A Sbjct: 1100 ATILGLVKVIPQEYPNLTCQHIDVSISDINFQQLVREINIPPVLSDTLPLEKGGLRMSVA 1159 Query: 1026 LRNNYIWEPAFKQVRLTTPLHAVHKRLTSXXXXXXXXXXXXXXXHVAKYLAEQYQAQVVL 1085 R W F+ + L P +T AK+LA A++V Sbjct: 1160 YRGKTRWIQEFQPISLPEPTQL--PLITGGVYVIAGDLVEGLGLIYAKFLAATVNAKLVF 1217 Query: 1086 LNRSQFLPEAEWDKWYAIHSGDDPVSQKIASLREIKAAASGFYLVQADITDAAQVRAVFG 1145 L RS EWD W A H D VS I L+ ++A F D+ + +QV Sbjct: 1218 LGRSDLPQPKEWDNWLATHGRQDAVSHCIQQLQGLQAQGCEFLFTTVDLAEISQVEDAIA 1277 Query: 1146 QILERCGAINGIIQAAGVPDGA--VIQRRSREMCEAVFGTKIYGTQVLQKVIGELSRPVD 1203 Q L R G ING+I A + D A +I+ + CE F TKI+G L+ + ++P+D Sbjct: 1278 QALTRFGKINGVIHAGVMGDRASCLIRNLTIPECEKQFHTKIHGLLALETALK--NQPLD 1335 Query: 1204 XXXXXXXXXXXXAPPAQVAYSAANSFLDAFAQINTKRGYFTQ-AINWD 1250 AY+ AN F+DA A T+ +INWD Sbjct: 1336 FFLLQSSLSAVVGGIGFAAYAGANCFMDAIAHQRTQNSNTHWISINWD 1383 >all2646 [Q] COG3321 Polyketide synthase modules and related proteins Length = 1488 Score = 691 bits (1784), Expect = 0.0, Method: Compositional matrix adjust. Identities = 415/1139 (36%), Positives = 603/1139 (52%), Gaps = 138/1139 (12%) Query: 4 NTRTGLEVAIIGMSGSFPGAKNLEQFFQNVKNGVDSISFFTDEQLAEAGVPAEVYTKENF 63 N TGLE+AIIG++G FPGA NLE+++QN++NGV+SI+ TDEQ+ + GV N+ Sbjct: 2 NNPTGLEIAIIGINGKFPGANNLEEYWQNLRNGVESITNLTDEQIQKNGVDPTQLKHPNY 61 Query: 64 VKAKGYLNECEYFDNSFFGYTPNEAQFMDPQTRLLHEHAWMALEDAGYPPGRTQDAIGVY 123 VK + ++ EYFD FFG+ P EA+ +DPQ RL E AW ALEDAGY P AIGVY Sbjct: 62 VKRQAIIDNIEYFDAEFFGFNPREAEILDPQHRLFLECAWTALEDAGYNPENYTGAIGVY 121 Query: 124 AGGRPHFHWEALSLSMGSRNGTEDFEIAHLNDKDLMSTRVSYKLNLKGPSYTLFTACSTS 183 AG + + L + +N +++ NDKD ++TRVSYKLNL+GPS + TACSTS Sbjct: 122 AGAAMNNYLLNLITNPQIQNQISRYQLFLSNDKDFLTTRVSYKLNLRGPSLDIQTACSTS 181 Query: 184 LVAVHAACQGVISGECDMAVAGGVSVTSPLQNGYFHQDGMILSSDGRCRAFDAASDGTVV 243 LVAVH ACQ ++SGECD+A+AGGVS+ GY +Q+G I S DG CRAFDA + GT+ Sbjct: 182 LVAVHVACQSLLSGECDIALAGGVSLAKA--TGYLYQEGGIYSPDGHCRAFDADAQGTIA 239 Query: 244 GNGIGLVILKRLEDALDDNDHIYAVIKGTAINNDGSRKVGYSAPSVDGQAEVIRTAHRVA 303 G+G+G+V+LKRL++A++D D+I+AVIKG+AINNDG KV Y+AP +D QA VIR A +A Sbjct: 240 GSGLGIVVLKRLQEAIEDRDYIHAVIKGSAINNDGGLKVSYTAPRIDTQAAVIRAAQALA 299 Query: 304 GVDPKEIGYIEAHGTGTALGDPIEVKALTTAFQ--TKRKHFCGLGSVKTNIGHLDSAAGI 361 GV+P +I YIE HGTGTALGDPIE+ ALT AF+ T++ FC + SVKTNIGHLD+AAGI Sbjct: 300 GVEPADISYIETHGTGTALGDPIEIAALTQAFRAGTEKTGFCAISSVKTNIGHLDAAAGI 359 Query: 362 AGLIKAVLALHNKCLLPTLHFANPNPHLMLEDSPFYLVDRMREWENGSGPRRAGVSSFGV 421 A LIK VLAL ++ + P LHF PNP + +PFY+ + +WE PRRAGVSSFG+ Sbjct: 360 ASLIKTVLALKHQQIPPNLHFQQPNPQIDFSQTPFYVNTNLVDWETDKTPRRAGVSSFGI 419 Query: 422 GGTNAHIVLEEAPSGQSVKQAEAQ--EQLLVFSAKTREALEQSIEAFVQDVQKNPGKASA 479 GGTNAH++LEEAP ++ ++ + Q+L SAK+ +ALE++ +Q++P A Sbjct: 420 GGTNAHVILEEAPIKFKIQNSKFKINYQMLCLSAKSEKALEEATINLATYLQQHPQFNLA 479 Query: 480 DIAYTLQQGREHFSYRQYVSCRTLLAGCAALRVKADQALWVDPKKELKP-VYFWFAGMA- 537 DIAYTL GR+HF+YR+ V C+T A ++ + + E P + F F G Sbjct: 480 DIAYTLHIGRQHFAYRRMVLCQT---TEEAAQILEKETKYTHTNSEKSPSIAFMFPGQGS 536 Query: 538 ---------------LEEAVQHYHSCLHHPYCREEMEELLLQASGIRGVKRDELLSGGSD 582 E + H L H ++ +L + I + Sbjct: 537 HYLNMGKELYETEAIFREQIDHCCELLQHDLGL-DLLSILFETESIPSPQSPVPSPQSQT 595 Query: 583 VYIGQTPVFLFQLALAKWLLRVGVKPAALMGTGTGAYVAGCLAGVFTLEEALMLMEKRDR 642 +Y Q +F+ + ALAK + G++P A++G G YV LAGVF+L + L L+ R R Sbjct: 596 IY-AQPALFIIEYALAKLWISWGIQPQAMIGHSLGEYVVATLAGVFSLPDVLKLVALRGR 654 Query: 643 LLEEW------------------------------------RGSEGDLFLLE-------- 658 L+++ G+E ++ LE Sbjct: 655 LMQQCPTGAMLSVGMSAAKLQPLLTDNLVIAAYNAPELCVVSGTEAEIVQLETNLNKQGI 714 Query: 659 -----------------ALQSEFYEAFDSVTLSAPAIPLLSADAGS-NTVLDVTLPDYWV 700 ++ + F AF +TL P IP +S G+ T T P YWV Sbjct: 715 SNRRLQTSHAFHSPLMESMITPFIAAFQKITLQTPKIPFISNVTGTWITAEQATDPHYWV 774 Query: 701 NALGADDDGKSLPAKAEEADKHLVLHFGA-------AGEPSGPSGYISLVKSGPE----- 748 N L + + + ++L GA A + + +S ++ + Sbjct: 775 NHLRQPVQFATGIKELLTEPQQILLEVGAGRTLATLAKQQTNSHTILSSLRHPQDTQSDV 834 Query: 749 --LLETVGCIWANGYPLQWDELAKHQNRARVILPTYPFTRKRYWVDTQQIKQFQNIWKRQ 806 LL+T+G +W G + W+ HQ R R+ LPTYPF R+RYW+D + +Q Sbjct: 835 AFLLQTLGQLWLAGVSIDWENFYTHQQRQRLPLPTYPFQRQRYWIDLKAGEQ-------- 886 Query: 807 EPQPGKEN-KEEWMYVPSWIRSEYMPEEREQQQGLI-AVFATQEPFVARCIERLEQMGHT 864 G EN +Y+PSW RS P+ ++ L VF I L+ +GH Sbjct: 887 ----GSENIPSPRLYLPSWERSLPHPQVDIAEKRLCWLVFTDNYGIYQEIINTLQAVGHD 942 Query: 865 IARIEAGESFQQNNL-SFEINPEXXXXXXXXXXXXXXXGDGPVRIVHFWCMHPQSAAREQ 923 + + GE + Q +F +NP+ P I++ W + +Q Sbjct: 943 VIIVSQGEKYDQPAYRTFTVNPQNSQDFVELWSDLELRELIPHHILYLWDL----TDLQQ 998 Query: 924 LPEAEECNRLGYYTLLNIARAVSQLQLQQPVTIDIVANQVAEVTGNETVVPAKATLFGPL 983 P +LL +A+A+S +++ +T+ +V N + GNE + P KAT++G Sbjct: 999 QP----------LSLLYLAQAISSQSIEREITLTLVTNDGQLLLGNENIQPMKATVWGMG 1048 Query: 984 RVIPKEYENIACRLIDTD-----QYDHHILCRILSGPENNRRADWIALRNNYIWEPAFK 1037 +VI +E + CR +D + I ++++ NN+ +A R NY W +K Sbjct: 1049 KVISQEIPQLTCRCVDISLSTVASTNEQIAQQLITECLNNQNDSVVAYRGNYRWNQIYK 1107 >AGl2313 [Q] COG3321 Polyketide synthase modules and related proteins Length = 211 Score = 559 bits (1441), Expect = e-158, Method: Compositional matrix adjust. Identities = 0/1146 (0%), Positives = 0/1146 (0%), Gaps = 158/1146 (13%) Query: 6 RTGLEVAIIGMSGSFPGAKNLEQFFQNVKNGVDSISFFTDEQLAEAGVPAEVYTKENFVK 65 + ++ + + Sbjct: 24 LNFSSPFELLIAVLLSAQATDVSVNKATAKLYPVANTPAAMLELGVEGVKTYIKTIGLYN 83 Query: 66 AKGYLNECEYFDNSFFGYTPNEAQFMDPQTRLLHEHAWMALEDAGYPPGRTQDAIGVYAG 125 +K + + T Sbjct: 84 SKAENIIKTCRILLEQHNGEVPEDRAALEALPGVGRKTANVVLNTAFGWPTIAVDTHIFR 143 Query: 126 GRPHFHWEALSLSMGSRNGTEDFEIAHLNDKDLMSTRVSYKLNLKGPSYTLFTACSTSLV 185 + A + + + L Sbjct: 144 VCNRTQFAPGKNVEQVEEKLLKVVPAEFKVDCHHWLILHGRYTCIARKPRCGSCIIEDLC 203 Query: 186 AVHAACQGVISGECDMAVAGGVSVTSPLQNGYFHQDGMILSSDGRCRAFDAASDGTVVGN 245 Sbjct: 204 -- 261 Query: 246 GIGLVILKRLEDALDDNDHIYAVIKGTAINNDGSRKVGYSAPSVDGQAEVIRTAHRVAGV 305 Sbjct: 262 321 Query: 306 DPKEIGYIEAHGTGTALGDPIEVKALTTAFQ--TKRKHFCGLGSVKTNIGHLDSAAGIAG 363 Sbjct: 322 381 Query: 364 LIKAVLALHNKCLLPTLHFANPNPHLMLEDSPFYLVDRMREWENGSGPRRAGVSSFGVGG 423 Sbjct: 382 441 Query: 424 TNAHIVLEEAPSGQS--VKQAEAQEQLLVFSAKTREALEQSIEAFVQDVQKNPGKASADI 481 Sbjct: 442 501 Query: 482 AYTLQQGREHFSYRQYVSCRTLLAGCAAL-RVKADQALWVDPKKELKPVYFW------FA 534 Sbjct: 502 -- 559 Query: 535 GMA--LEEAVQHYHSCLHHPY--CREEMEELLLQASGIRGVKRDELLSGGSDVY---IGQ 587 Sbjct: 560 ---------- 609 Query: 588 TPVFLFQLALAKWLLRVGVKPAALMGTGTGAYVAGCLAGVFTLEEALMLMEKRDRLLEE- 646 Sbjct: 610 669 Query: 647 -----------------WRGSE---------------GDLFLLEALQSE----------- 663 Sbjct: 670 729 Query: 664 -----------------FYEAFDSVTLSAPAIPLLSADAGS-NTVLDVTLPDYWVNALGA 705 Sbjct: 730 789 Query: 706 D---DDGKSLPAKAEEADKHLVLHFGAAGEPSGPSGYI------------SLVKSGPE-- 748 Sbjct: 790 ------ 843 Query: 749 ---LLETVGCIWANGYPLQWDELAKHQNRARVILPTYPFTRKRYWVDTQQIKQFQNIWKR 805 Sbjct: 844 --------- 894 Query: 806 QEPQPGKENKEEWMYVPSWIR-SEYMPEEREQQQGLIAVFATQEPFVARCI-ERLEQMGH 863 Sbjct: 895 ----- 949 Query: 864 TIARIEAGESFQQNNL-SFEINPEXXXXXXXXXXXXXXXGDGPVRIVHFWCMHPQSAARE 922 Sbjct: 950 --- 1006 Query: 923 QLPEAEECNRLGYYTLLNIARAVSQLQLQQPVTIDIVANQVAEVTGNETVVPAKATLFGP 982 Sbjct: 1007 ------------ 1054 Query: 983 LRVIPKEYENIACRLIDT----DQYDHHILCRILSGPENNRRADWIALRNNYIWEPAFKQ 1038 Sbjct: 1055 -- 1112 Query: 1039 VRLTTP 1044 Sbjct: 1113 1118 >AGl2329 [Q] COG3321 Polyketide synthase modules and related proteins Length = 211 Score = 460 bits (1184), Expect = e-128, Method: Compositional matrix adjust. Identities = 0/661 (0%), Positives = 0/661 (0%), Gaps = 26/661 (3%) Query: 5 TRTGLEVAIIGMSGSFPGAKNLEQFFQNVKNGVDSISFFTDEQLAEAGVPAEVYTKENFV 64 L +S + AK + ++ Sbjct: 34 IAVLLSAQATDVSVNKATAKLYPVANTPAAMLELGVEGVKTYIKTIGLYNSKAENIIKTC 93 Query: 65 KAKGYLNECEYFDNSFFGYTPNEAQFMDPQTRLLHEHAWMALEDAGYPPGRTQDAIGVYA 124 + + E ++ L W + + Sbjct: 94 RILLEQHNGEVPEDRAALEALPGVGRKTANVVLNTAFGWPTIAVDTHIFRVCNRTQFAPG 153 Query: 125 GGRPHFHWEALSLSMGSRNGTEDFEIAHLNDKDLMSTRVSYKLNLKGPSYTLFTACSTSL 184 Sbjct: 154 213 Query: 185 VAVHAACQGVISGECDMAVAGGVSVTSPLQNGYFHQDGMILSSDGRCRAFDAASDGTVVG 244 Sbjct: 214 273 Query: 245 NGIGLVILKRLEDALDDNDHIYAVIKGTAINNDGSRKVGYSAPSVDGQAEVIRTAHRVAG 304 Sbjct: 274 333 Query: 305 VDPKEIGYIEAHGTGTALGDPIEVKALTTAFQTKRK---HFCGLGSVKTNIGHLDSAAGI 361 Sbjct: 334 393 Query: 362 AGLIKAVLALHNKCLLPTLHFANPNPHLMLEDSPFYLVDRMREWE-NGSGPRRAGVSSFG 420 Sbjct: 394 453 Query: 421 VGGTNAHIVLEEAPSGQSVKQAEAQEQLL---VFSAKTREALEQSIEAFVQDVQKNPGKA 477 Sbjct: 454 513 Query: 478 SADIAYTLQQGREHFSYRQYVSCRTLLAGCAALRVKADQALWVDPKKELKP-VYFWFAGM 536 Sbjct: 514 573 Query: 537 ---------ALEEAVQHYHSCLHHPYCREEMEELLLQASGIRGV---KRDELLSGGSDVY 584 Sbjct: 574 ------ 627 Query: 585 IGQTPVFLFQLALAKWLLRVGVKPAALMGTGTGAYVAGCLAGVFTLEEALMLMEKRDRLL 644 Sbjct: 628 687 Query: 645 E 645 Sbjct: 688 688 >ML2353_1 [Q] COG3321 Polyketide synthase modules and related proteins Length = 1031 Score = 457 bits (1176), Expect = e-127, Method: Compositional matrix adjust. Identities = 272/673 (40%), Positives = 383/673 (56%), Gaps = 46/673 (6%) Query: 11 VAIIGMSGSFPGAKNLEQFFQNVKNGVDSISFFTDEQLAEAGVPAEVYTKENFVKAKGYL 70 +A++GM+G FPGA ++ F+ N++ G +SI ++++L + GV + +V+ L Sbjct: 8 IAVVGMAGKFPGANDVSAFWTNLRRGKESIVTLSEQELRDNGVSDKALADPAYVRRAPLL 67 Query: 71 NECEYFDNSFFGYTPNEAQFMDPQTRLLHEHAWMALEDAGYPPGRTQDAIGVYAGGRPHF 130 + + FD FFG P AQ +DPQ RL + AW ALEDAG P + +IGVY P Sbjct: 68 DGIDEFDADFFGLPPLAAQVLDPQHRLFLQCAWHALEDAGCDPAQFDGSIGVYGTSSPSG 127 Query: 131 HWEALSLS-------MGSRNGTEDFEIAHLNDKDLMSTRVSYKLNLKGPSYTLFTACSTS 183 + LS + + F + NDKD ++TR+S+ NL+GPS + TACS+S Sbjct: 128 YLLHNLLSHRDPHTVLAEGLNFDQFSLFLQNDKDFLATRISHAFNLRGPSIAVQTACSSS 187 Query: 184 LVAVHAACQGVISGECDMAVAGGVSVTSPLQNGYFHQDGMILSSDGRCRAFDAASDGTVV 243 LVA+H AC ++SGECDMA+AGG S+ P + GY+H G ++S+ G CR FD +DGTV Sbjct: 188 LVALHLACLSLLSGECDMALAGGSSLCIPHRVGYWHSPGSMVSAVGHCRPFDVRADGTVF 247 Query: 244 GNGIGLVILKRLEDALDDNDHIYAVIKGTAINNDGSRKVGYSAPSVDGQAEVIRTAHRVA 303 G+G+ LV LK L+ A+D +D I+AVI G+AINNDGS K+GY+AP+ QA+VI AH VA Sbjct: 248 GSGVALVALKPLQAAIDASDRIHAVILGSAINNDGSMKMGYAAPNPAAQADVIAEAHAVA 307 Query: 304 GVDPKEIGYIEAHGTGTALGDPIEVKALTTAF---QTKRKHFCGLGSVKTNIGHLDSAAG 360 G+D + Y+E HGTGT LGDPIE++ L TAF Q R C LGSVK+NIGHL+ AAG Sbjct: 308 GIDSSTVSYVETHGTGTPLGDPIEIQGLKTAFEVSQIPRPGPCVLGSVKSNIGHLEVAAG 367 Query: 361 IAGLIKAVLALHNKCLLPTLHFANPNPHLMLEDSPFYLVDRMREWENGSGPRRAGVSSFG 420 IAGLIK +L L NK + TLH+ +PN L L+ +PF + W+ G RRAGVSSFG Sbjct: 368 IAGLIKTILCLKNKAIPATLHYTSPNRELRLDQTPFVVQSNYGPWK-WDGVRRAGVSSFG 426 Query: 421 VGGTNAHIVLEEAPSGQSVKQAEAQEQLLVFSAKTREALEQSIEAFVQDVQKNPGKASAD 480 VGGTN H+VLEEA S A Q+++ SA+T AL +S EA ++K +D Sbjct: 427 VGGTNVHVVLEEASVEASTVAASTGPQVILLSAQTAAALGESREALATVLEKPGAPDLSD 486 Query: 481 IAYTLQQGREH-----FSYRQYVSCRTLL--------------------AGCAALRVKAD 515 +AYTL R+H R T+L A + + +D Sbjct: 487 VAYTLAGRRKHNITMAAVVRDREHAVTVLRAAEHDNVFVGESGADTGRSAAASITTLGSD 546 Query: 516 QALWVDPKKELKPVYFWFAGMALEEAV--QHYHSCLHHPYCREEMEELLLQASGIRGVKR 573 + +++ P + + V G+ E+V +H+ +C RE M++L L ++ G Sbjct: 547 RVVFLFPGQGAQHVGM-AKGLYDTESVFAEHFDTC--SAGFREAMDDLDLHSAIFNGTAI 603 Query: 574 DELLSGGSDVYIGQTPVFLFQLALAKWLLRVGVKPAALMGTGTGAYVAGCLAGVFTLEEA 633 D + Q +F + ALAK + GV A +G TG Y+A LAGVF LE A Sbjct: 604 DL-----ERIDRSQPALFTVEYALAKLVESFGVGAGAYIGYSTGEYIAATLAGVFDLETA 658 Query: 634 LMLMEKRDRLLEE 646 + + R RL+ E Sbjct: 659 IKTVSLRARLMHE 671 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.319 0.135 0.404 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 159,107,412 Number of extensions: 6638921 Number of successful extensions: 22858 Number of sequences better than 1.0e-05: 143 Number of HSP's gapped: 22316 Number of HSP's successfully gapped: 180 Length of query: 2184 Length of database: 38,378,431 Length adjustment: 122 Effective length of query: 2062 Effective length of database: 24,307,683 Effective search space: 50122442346 Effective search space used: 50122442346 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 124 (52.4 bits)