BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0489.0026.p (1557 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value all2646 [Q] COG3321 Polyketide synthase modules and related prot... 473 e-132 all2635 [Q] COG3321 Polyketide synthase modules and related prot... 460 e-129 AGl2313 [Q] COG3321 Polyketide synthase modules and related prot... 437 e-122 AGl2329 [Q] COG3321 Polyketide synthase modules and related prot... 383 e-105 RSc1810_1 [Q] COG3321 Polyketide synthase modules and related pr... 369 e-101 >all2646 [Q] COG3321 Polyketide synthase modules and related proteins Length = 1488 Score = 473 bits (1217), Expect = e-132, Method: Compositional matrix adjust. Identities = 276/655 (42%), Positives = 368/655 (56%), Gaps = 41/655 (6%) Query: 1 LEIAVIGLAGRFPGAGTISEYWDNLKNGVHSVQTFSEQELIAAGVEPGLAAKAEYVKAKG 60 LEIA+IG+ G+FPGA + EYW NL+NGV S+ +++++ GV+P YVK + Sbjct: 7 LEIAIIGINGKFPGANNLEEYWQNLRNGVESITNLTDEQIQKNGVDPTQLKHPNYVKRQA 66 Query: 61 YLEAGHCFDARFFDYTPLEAELMDPQMKVFHECIWXXXXXXXXXXXXXQQLIGLFAGASP 120 ++ FDA FF + P EAE++DPQ ++F EC W IG++AGA+ Sbjct: 67 IIDNIEYFDAEFFGFNPREAEILDPQHRLFLECAWTALEDAGYNPENYTGAIGVYAGAAM 126 Query: 121 NHVWEGLMGLSGKSGVMGHWAASQLL---DKDYLSLRIAHKLNLKGPALSIYTACSTSLV 177 N+ L+ L + + QL DKD+L+ R+++KLNL+GP+L I TACSTSLV Sbjct: 127 NNY---LLNLITNPQIQNQISRYQLFLSNDKDFLTTRVSYKLNLRGPSLDIQTACSTSLV 183 Query: 178 AVHMAAQSLLNGECDIALAGGVTVTLPEKSGYEYQEGMILSPDGKCRAFXXXXXXXXXXX 237 AVH+A QSLL+GECDIALAGGV+ L + +GY YQEG I SPDG CRAF Sbjct: 184 AVHVACQSLLSGECDIALAGGVS--LAKATGYLYQEGGIYSPDGHCRAFDADAQGTIAGS 241 Query: 238 XXXXXVLKRLQDALDDGDQIYAVIKGSAVNNDGLQKTGFTAPSTIGQAEVIRTALKLAEV 297 VLKRLQ+A++D D I+AVIKGSA+NNDG K +TAP QA VIR A LA V Sbjct: 242 GLGIVVLKRLQEAIEDRDYIHAVIKGSAINNDGGLKVSYTAPRIDTQAAVIRAAQALAGV 301 Query: 298 SPDSIDYIECHGTGTPLGDPIELEALELGY--NPERRHACALGSVKTNIGHLDSAAGIAS 355 P I YIE HGTGT LGDPIE+ AL + E+ CA+ SVKTNIGHLD+AAGIAS Sbjct: 302 EPADISYIETHGTGTALGDPIEIAALTQAFRAGTEKTGFCAISSVKTNIGHLDAAAGIAS 361 Query: 356 FIKTVLALKHNILPPSLHFQTPNPVLKVIEKGFYINDRLTEWPSKNEPLRAGISAFGIGG 415 IKTVLALKH +PP+LHFQ PNP + + FY+N L +W + P RAG+S+FGIGG Sbjct: 362 LIKTVLALKHQQIPPNLHFQQPNPQIDFSQTPFYVNTNLVDWETDKTPRRAGVSSFGIGG 421 Query: 416 TNAHIIVEQAPPPREASAGR---EWQLLPVSAKTPSALAEIKQDLERYSKTEPR-RLEDI 471 TNAH+I+E+AP + + +Q+L +SAK+ AL E +L Y + P+ L DI Sbjct: 422 TNAHVILEEAPIKFKIQNSKFKINYQMLCLSAKSEKALEEATINLATYLQQHPQFNLADI 481 Query: 472 AYTLQVGRKHFPIRELALVNRKSQRVLQFAETATMKGTAGLENAPVI-FVIPDFTQRXXX 530 AYTL +GR+HF R + L + ++ Q E T E +P I F+ P Sbjct: 482 AYTLHIGRQHFAYRRMVLC-QTTEEAAQILEKETKYTHTNSEKSPSIAFMFPGQGSHYLN 540 Query: 531 XXXXXXXXXXXXXXPGARRFLNQVLGMMNRLVPDGAAVKLEDLRKRE-------YHPVLA 583 F Q+ L D L L + E P Sbjct: 541 MGKELYETEAI--------FREQIDHCCELLQHDLGLDLLSILFETESIPSPQSPVPSPQ 592 Query: 584 FGSYYAVGKLFI----------EWGLHPEAVIGRGKSQWLAACLSGELSLEEAVR 628 + YA LFI WG+ P+A+IG +++ A L+G SL + ++ Sbjct: 593 SQTIYAQPALFIIEYALAKLWISWGIQPQAMIGHSLGEYVVATLAGVFSLPDVLK 647 Score = 186 bits (471), Expect = 3e-46, Method: Compositional matrix adjust. Identities = 185/721 (25%), Positives = 308/721 (42%), Gaps = 88/721 (12%) Query: 652 EEIWLVLGAGNEAQPFLDKQSSKPQIIAL------EKLNTYSLMAAVGTMWLYGQDIKWR 705 ++I L +GAG +Q++ I++ + + L+ +G +WL G I W Sbjct: 795 QQILLEVGAGRTLATLAKQQTNSHTILSSLRHPQDTQSDVAFLLQTLGQLWLAGVSIDWE 854 Query: 706 ELYQHEQRNRLSLPTYAFDRQEFPVDPELFNLNHLLNRPPSGKGGTPADRDDIRKWFYIP 765 Y H+QR RL LPTY F RQ + +D L G P+ R Y+P Sbjct: 855 NFYTHQQRQRLPLPTYPFQRQRYWID---------LKAGEQGSENIPSPR------LYLP 899 Query: 766 AWESAALPNYEGRMLSRDAAWFIFCDPGGLGEALGDLLRQQQIRCIMVEHAEHYQQITAD 825 +WE +LP+ + + + W +F D G+ + + + L+ I+V E Y Q Sbjct: 900 SWER-SLPHPQVDIAEKRLCWLVFTDNYGIYQEIINTLQAVGHDVIIVSQGEKYDQPAYR 958 Query: 826 HYRVNPLRSEEMDRLYHSL---DAVPDHICYLWTVTSPMEPELANIETGQQLFLHHILRL 882 + VNP S++ L+ L + +P HI YLW +T + L+ +L L Sbjct: 959 TFTVNPQNSQDFVELWSDLELRELIPHHILYLWDLTDLQQQPLS------------LLYL 1006 Query: 883 VQFLGTAAAAQEVHLQIVSNGLYSITQEEMLCPMKGLLLGASKIIPYEYPNIKVCHVDFP 942 Q + + + +E+ L +V+N + E + PMK + G K+I E P + VD Sbjct: 1007 AQAISSQSIEREITLTLVTNDGQLLLGNENIQPMKATVWGMGKVISQEIPQLTCRCVDIS 1066 Query: 943 LAEGDPARQREQ-ARQMLREFQFEFPNKQVAYRGKSRWIEAVQKPLLL-ASPGKVSLFR- 999 L+ A EQ A+Q++ E + VAYRG RW + KPLL+ + K+S+ Sbjct: 1067 LS--TVASTNEQIAQQLITECLNNQNDSVVAYRGNYRW-NQIYKPLLMDDAQSKISVHEG 1123 Query: 1000 NNLVCMITXXXXXXXXXXXXXXXTQYTARLVLVGRSAFPPKSEWDQWMNRPDDAEVARII 1059 N V I + + RLVL+ I Sbjct: 1124 GNYV--ILGDLTTGLGTVFAEFLMKNSVRLVLLSDV----------------------IT 1159 Query: 1060 RTIR-ALEAAGAVIEVHSADISDFSAMQQVVARAEARLGPITGVLHTAGVAD--YAGVIQ 1116 T++ +L+ G + DI+ + ++ +A+AE + G I GV ++ +++ + Sbjct: 1160 ETLKQSLDNVGIDYLSLNIDITKQAELENAIAQAETKFGQINGVFYSTPMSNEHSMAFLP 1219 Query: 1117 RRTQAMTDEVLLPKVKGTLVLDTLFRNRRLDFFVLFSSIGNYIYGRKFGQVGYNAANEFL 1176 + T + K++G VL + R++ LDF VL SS+ + G G Y AAN + Sbjct: 1220 QLTTKHWEYNYRTKIQGLCVLAEVLRDKPLDFCVLQSSLSTVLGG--LGLAVYAAANAVI 1277 Query: 1177 DAFVHYRLQNREGFTATINWNDWAEAGMSVKAMEKNRSLHKAVNDLQFEAEAITTEQGVN 1236 D F + QN + +INW +A S + N S + L A+T + Sbjct: 1278 DMFAIQQNQNSKFPWISINW----DACRSDLETDINHSFAANLVTL-----ALTPAEVWQ 1328 Query: 1237 VFRYIMENQM-NRVIVSALDLPALMEE-SNNISVEVILEQXXXXXXXXXXXXXXGSSSLL 1294 ++I++ + V+V+ DL +E+ N + E + Sbjct: 1329 STQHIIKLGLPESVVVTKSDLDKRLEKWVTNTPTKTKTETNNSYTRPQLTNEYIAPRDEI 1388 Query: 1295 TEAGLQQQIADIWSTVLGIEAIGIDEDFFALGGDSLKAITIVSLVFKKLGVKLPLPAFFH 1354 A IA IW +LGI IGI++ FF LGG SL AI +S + + GV+L + + Sbjct: 1389 ETA-----IAQIWQDLLGISPIGINDSFFDLGGHSLLAIQAISRLRDRFGVELSMRNLLY 1443 Query: 1355 K 1355 + Sbjct: 1444 E 1444 >all2635 [Q] COG3321 Polyketide synthase modules and related proteins Length = 1565 Score = 460 bits (1184), Expect = e-129, Method: Compositional matrix adjust. Identities = 262/666 (39%), Positives = 377/666 (56%), Gaps = 49/666 (7%) Query: 2 EIAVIGLAGRFPGAGTISEYWDNLKNGVHSVQTFSEQELIAAGVEPGLAAKAEYVKAKGY 61 E+A++G+AGRFPGA + E+WDNLKNG++S++ S ++L+A GV+ K YV+A Sbjct: 38 EVAIVGMAGRFPGAKNVDEFWDNLKNGINSIKFLSNEDLLANGVKAEDLEKQNYVRAYAS 97 Query: 62 LEAGHCFDARFFDYTPLEAELMDPQMKVFHECIWXXXXXXXXXXXXXQQLIGLFAGASPN 121 L FDA FF Y+P EAE++DPQ ++F EC W I ++ GA+ N Sbjct: 98 LAGIDEFDAGFFGYSPREAEILDPQHRLFLECAWEALENAGYDSEQYSGNIAVYGGAALN 157 Query: 122 HVWEGLMGLSGKSGVMGHWAASQLLDKDYLSL---RIAHKLNLKGPALSIYTACSTSLVA 178 L+ L+ S + +Q++ + + L R+++KLNL G + I T CSTSLV+ Sbjct: 158 SY---LVNLASNSNYRENSDRTQVVISNVMGLMPTRVSYKLNLTGASCGIQTGCSTSLVS 214 Query: 179 VHMAAQSLLNGECDIALAGGVTVTLPEKSGYEYQEGMILSPDGKCRAFXXXXXXXXXXXX 238 VH+A QSLLN ECDIALAGGV++ + EK+GY YQE +LSPDG CRAF Sbjct: 215 VHIACQSLLNKECDIALAGGVSIGIGEKAGYLYQEDGVLSPDGYCRAFDVNAKGTVFGNG 274 Query: 239 XXXXVLKRLQDALDDGDQIYAVIKGSAVNNDGLQKTGFTAPSTIGQAEVIRTALKLAEVS 298 VLKRL+DA+ DGD IYA+IK +A+NNDG QK G TAPS GQA+ I TAL A+++ Sbjct: 275 VGIVVLKRLRDAIQDGDHIYAIIKATAINNDGSQKVGLTAPSVTGQAKAITTALTKAKIN 334 Query: 299 PDSIDYIECHGTGTPLGDPIELEALELGYNPE--RRHACALGSVKTNIGHLDSAAGIASF 356 P++I YIE HGTGT LGDPIE+ AL ++P ++ CA+GSVKTNIGHLD+AAGI+ Sbjct: 335 PETIQYIETHGTGTALGDPIEIAALTKAFSPHTHQKQFCAVGSVKTNIGHLDAAAGISGL 394 Query: 357 IKTVLALKHNILPPSLHFQTPNPVLKVIEKGFYINDRLTEWPSKNEPLRAGISAFGIGGT 416 IKT LALKH +PPSL+F NP + F++N +LT W + P RAG+S+FG+GGT Sbjct: 395 IKTALALKHKQIPPSLNFTAANPQIDFANSPFFVNTQLTPWINHQHPRRAGVSSFGMGGT 454 Query: 417 NAHIIVEQAPPPREASAGR---EWQLLPVSAKTPSALAEIKQDLERYSKTEPR-RLEDIA 472 NAH I+E+AP + + + LL +SAK+ AL + +L + + P L D+A Sbjct: 455 NAHAILEEAPTQFKIQNSKFKINYHLLCLSAKSEKALEQATINLATHLQKHPELNLADVA 514 Query: 473 YTLQVGRKHFPIRELALVNRKSQ--RVLQFAETATMKGTAGLENAP-VIFVIPDFTQRXX 529 YTLQ+GR+ F R + +Q +L + + + + P ++F+ P Sbjct: 515 YTLQIGRRAFNHRRCLVCQTPAQAIEILTGVDASQLLSYSPENTEPSIVFMFPG-----Q 569 Query: 530 XXXXXXXXXXXXXXXPGARRFLNQVLGMM------------------NRLVPDGAAVKLE 571 P R+ ++ ++ N P L Sbjct: 570 GSQYLNMGQELYNTEPVFRKEIDHCSELLQPHLGCDLPSILFKQDNENSPSPQSPVPNLN 629 Query: 572 -DLRKREY---------HPVLAFGSYYAVGKLFIEWGLHPEAVIGRGKSQWLAACLSGEL 621 +LR Y P L F YA+ KL++ +G+ P+A+IG +++AA L+G Sbjct: 630 YELRITNYELLTQTTYAQPAL-FAVEYALAKLWLSYGIQPQAMIGHSIGEYVAATLAGVF 688 Query: 622 SLEEAV 627 +L +A+ Sbjct: 689 TLADAL 694 Score = 243 bits (620), Expect = 2e-63, Method: Compositional matrix adjust. Identities = 196/690 (28%), Positives = 313/690 (45%), Gaps = 74/690 (10%) Query: 688 LMAAVGTMWLYGQDIKWRELYQHEQRNRLSLPTYAFDRQEFPVDPELFNLNHLLNRPPSG 747 + +G +WL G I W ELY +QR RL LPTY F+RQ + V+ + L S Sbjct: 885 ICKTLGQLWLRGVTINWSELYTQQQRRRLPLPTYPFERQRYWVERD------TLPETTSN 938 Query: 748 KGGTPADRDDIRKWFYIPAWESAALPNYEGRMLSRDAAWFIFCDPGGLGEALGDLLRQQQ 807 T ++ I WFY+P+W L + + +FC G GE L L++ Sbjct: 939 TSKTLQKQEQISNWFYLPSWRQKPLLRSAAPL--NKQRYLVFCHAGNAGERLVQHLQETG 996 Query: 808 IRCIMVEHAEHYQQITADHYRVNPLRSEEMDRLYHSL---DAVPDHICYLWTVTSPMEPE 864 + V+ E + Q D+Y + P E+ L+ L D +PD I + WT+ E Sbjct: 997 QEVVTVKPGEGFTQ-EGDNYAIAPHNPEDYKTLWLQLQTDDKLPDVIIHSWTLQ-----E 1050 Query: 865 LANIETGQQLFLHHILRLVQFLGTAAAAQEVHLQIVSNGLYSITQEEMLCPMKGLLLGAS 924 N + Q L + +L L Q L +++ + V Q V N + E L P +LG Sbjct: 1051 RTNFQQQQNLGFYSLLWLTQALSSSSLSIYVLTQQVQN----VLGNENLNPDDATILGLV 1106 Query: 925 KIIPYEYPNIKVCHVDFPLAEGDPARQREQARQMLREFQF------EFPNKQ------VA 972 K+IP EYPN+ H+D +++ + +Q++RE P ++ VA Sbjct: 1107 KVIPQEYPNLTCQHIDVSISDIN-------FQQLVREINIPPVLSDTLPLEKGGLRMSVA 1159 Query: 973 YRGKSRWIEAVQKPLLLASPGKVSLFRNNLVCMITXXXXXXXXXXXXXXXTQYTARLVLV 1032 YRGK+RWI+ Q P+ L P ++ L + + A+LV + Sbjct: 1160 YRGKTRWIQEFQ-PISLPEPTQLPLITGGVYVIAGDLVEGLGLIYAKFLAATVNAKLVFL 1218 Query: 1033 GRSAFPPKSEWDQWM---NRPDDAEVARIIRTIRALEAAGAVIEVHSADISDFSAMQQVV 1089 GRS P EWD W+ R D V+ I+ ++ L+A G + D+++ S ++ + Sbjct: 1219 GRSDLPQPKEWDNWLATHGRQD--AVSHCIQQLQGLQAQGCEFLFTTVDLAEISQVEDAI 1276 Query: 1090 ARAEARLGPITGVLHTAGVADYAGVIQRR-TQAMTDEVLLPKVKGTLVLDTLFRNRRLDF 1148 A+A R G I GV+H + D A + R T ++ K+ G L L+T +N+ LDF Sbjct: 1277 AQALTRFGKINGVIHAGVMGDRASCLIRNLTIPECEKQFHTKIHGLLALETALKNQPLDF 1336 Query: 1149 FVLFSSIGNYIYGRKFGQVGYNAANEFLDAFVHYRLQNREGFTATINWNDWAEAGMSVKA 1208 F+L SS+ + G F Y AN F+DA H R QN +INW+ +V Sbjct: 1337 FLLQSSLSAVVGGIGFA--AYAGANCFMDAIAHQRTQNSNTHWISINWD-------AVSL 1387 Query: 1209 MEKNRSLHKAVNDLQFEAEAITTEQGVNVFRYIMENQM-NRVIVSALDLPALMEESNNIS 1267 E S + DL A+T+++ V I+ + ++ VS +DL + + Sbjct: 1388 AEITTSTGATLIDL-----AMTSQEVWQVTERILAQPIAAQITVSPVDLASRQQSQP--- 1439 Query: 1268 VEVILEQXXXXXXXXXXXXXXGSSSLLTEAGLQQQIADIWSTVLGIEAIGIDEDFFALGG 1327 LEQ ++ L ++ ++ + ++LGI IG++++FF LGG Sbjct: 1440 ----LEQSTTNHARPQIT----ATYLPPSNEIEARVTQVMESLLGIAPIGVNDNFFELGG 1491 Query: 1328 DSLKAITIVSLVFKKLGVKLPLPAF-FHKP 1356 SL AI VS + ++ V+LP+ F F P Sbjct: 1492 HSLLAIQAVSQLREEFQVELPMRQFLFESP 1521 >AGl2313 [Q] COG3321 Polyketide synthase modules and related proteins Length = 211 Score = 437 bits (1125), Expect = e-122, Method: Compositional matrix adjust. Identities = 0/636 (0%), Positives = 0/636 (0%), Gaps = 15/636 (2%) Query: 1 LEIAVIGLAGRFPGAGTISEYWDNLKNGVHSVQTFSEQELIAAGVEPGLAAKAEYVKAKG 60 + +A T T + + +K Sbjct: 27 SSPFELLIAVLLSAQATDVSVNKATAKLYPVANTPAAMLELGVEGVKTYIKTIGLYNSKA 86 Query: 61 YLEAGHCFDARFFDYTPLEAELMDPQMKVFHECIWXXXXXXXXXXXXXQQLIGLFAGASP 120 C + + + + Sbjct: 87 ENIIKTCRILLEQHNGEVPEDRAALEALPGVGRKTANVVLNTAFGWPTIAVDTHIFRVCN 146 Query: 121 NHVWEGLMGLSGKSGVMGHWAASQLL---DKDYLSLRIAHKLNLKGPALSIYTACSTSLV 177 V + L + + + L Sbjct: 147 RTQ---FAPGKNVEQVEEKLLKVVPAEFKVDCHHWLILHGRYTCIARKPRCGSCIIEDLC 203 Query: 178 AVHMAAQSLLNGECDIALAGGVTVTLPEKSGYEYQEGMILSPDGKCRAFXXXXXXXXXXX 237 Sbjct: 204 -- 261 Query: 238 XXXXXVLKRLQDALDDGDQIYAVIKGSAVNNDGLQKTGFTAPSTIGQAEVIRTALKLAEV 297 Sbjct: 262 321 Query: 298 SPDSIDYIECHGTGTPLGDPIELEALELGY--NPERRHACALGSVKTNIGHLDSAAGIAS 355 Sbjct: 322 381 Query: 356 FIKTVLALKHNILPPSLHFQTPNPVLKVIEKGFYINDRLTEWPSKNEPLRAGISAFGIGG 415 Sbjct: 382 441 Query: 416 TNAHIIVEQAPPPREASAGRE---WQLLPVSAKTPSALAEIKQDLERYSKTEPR-RLEDI 471 Sbjct: 442 501 Query: 472 AYTLQVGRKHFPIRELALVNRKSQRVLQFAETATMKGTAGLENAPVIFVIPDFTQRXXXX 531 Sbjct: 502 561 Query: 532 XXXXXXXXXXXXXPGARRFLNQVLGMMNRLVPDGAAVKLEDLRKREYHPVLAFGSYYAVG 591 Sbjct: 562 - 620 Query: 592 KLFIEWGLHPEAVIGRGKSQWLAACLSGELSLEEAV 627 Sbjct: 621 656 Score = 77.0 bits (188), Expect = 2e-13, Method: Compositional matrix adjust. Identities = 0/682 (0%), Positives = 0/682 (0%), Gaps = 108/682 (15%) Query: 685 TYSLMAAVGTMWLYGQDIKWRELYQHEQRNRLSLPTYAFDRQEFPVDPELFNLNHLLNRP 744 Sbjct: 844 ------- 896 Query: 745 PSGKGGTPADRDDIRKWFYIPAWE--SAALP-NYEGRMLSRDAAWFIFCDPGGLGEALGD 801 Sbjct: 897 -------------- 942 Query: 802 LLRQQQIRCIMVEHAEHYQQITADHYRVNPLRSEEMDRLYHSLD---AVPDHICYLWTVT 858 Sbjct: 943 --- 999 Query: 859 SPMEPELANIETGQQLFLHHILRLVQFLGTAAAAQEVHLQIVSNGLYSITQEEMLCPMKG 918 Sbjct: 1000 ---------- 1049 Query: 919 LLLGASKIIPYEYPNIKVCHVDFPLAEGDPARQREQARQMLREFQFEFPNKQVAYRGKSR 978 Sbjct: 1050 ---- 1105 Query: 979 WIEAVQKPLLLASPGKVSLFRNNLVCMITXXXXXXXXXXXXXXXTQYTARLVLVGRSAFP 1038 Sbjct: 1106 -------------------------- 1139 Query: 1039 PKSEWDQWMNRPDDAEVARIIRTIRALEAA---GAVIEVHSADISDFSAMQQVVARAEAR 1095 Sbjct: 1140 - 1198 Query: 1096 LGPITGVLHTAGVADYAGVIQRRTQAMTDEVLLP-----KVKGTLVLDTLFRNRRLDFFV 1150 Sbjct: 1199 --- 1255 Query: 1151 LFSSIGNYIYGRKFGQVGYNAANEFLDAFVHYRLQNREGFTATINWNDWAEAGMSVKAME 1210 Sbjct: 1256 ------- 1308 Query: 1211 KNRSLHKAVNDLQFEAEAITTEQGVNVFRYIMENQMNRVIVSALDLPALMEESNNISVEV 1270 Sbjct: 1309 ---------------- 1352 Query: 1271 IL---EQXXXXXXXXXXXXXXGSSSLLTEAGLQQQIADIWSTVLGIEAIGIDEDFFALGG 1327 Sbjct: 1353 1412 Query: 1328 DSLKAITIVSLVFKKLGVKLPL 1349 Sbjct: 1413 1434 >AGl2329 [Q] COG3321 Polyketide synthase modules and related proteins Length = 211 Score = 383 bits (984), Expect = e-105, Method: Compositional matrix adjust. Identities = 0/648 (0%), Positives = 0/648 (0%), Gaps = 33/648 (5%) Query: 3 IAVIGLAGRFPGAGTISEYWDNLKNGVHSVQTFSEQELIAAGVEPGLAAKAEYVKAKGYL 62 ++ A V+ + + Sbjct: 40 AQATDVSVNKATAKLYPVANTPAAMLELGVEGVKTYIKTIGLYNSKAENIIKTCRILLEQ 99 Query: 63 EAGHCFDARFFDYTPLEAELMDPQMKVFHECIWXXXXXXXXXXXXXQQLIGLFAGASPNH 122 G + R + + W + Sbjct: 100 HNGEVPEDRAALEALPGVGRKTANVVLNTAFGWPTIAVDTHIFRVCNRTQFAPGKNVEQV 159 Query: 123 VWEGLMGLSGKSGVMGHWAASQLLDKDYLSLRIAHKLNLKGPALSIYTACSTSLVAVHMA 182 Sbjct: 160 219 Query: 183 AQSLLNGECDIALAGGVTVTLPEKSGYEYQEGMILSPDGKCRAFXXXXXXXXXXXXXXXX 242 Sbjct: 220 279 Query: 243 VLKRLQDALDDGDQIYAVIKGSAVNNDGLQKTGFTAPSTIGQAEVIRTALKLAEVSPDSI 302 Sbjct: 280 339 Query: 303 DYIECHGTGTPLGDPIELEALELGYNPERR---HACALGSVKTNIGHLDSAAGIASFIKT 359 Sbjct: 340 399 Query: 360 VLALKHNILPPSLHFQTPNPVLKVIEKGFYINDRLTEWPSK-NEPLRAGISAFGIGGTNA 418 Sbjct: 400 459 Query: 419 HIIVEQAPPPREASAGREWQ-LLPVSAKTPSALAEIKQDLE----RYSKTEPRRLEDIAY 473 Sbjct: 460 519 Query: 474 TLQVGRKHFPIRELAL---VNRKSQRVLQFAETATMKGTAGLENAPVIFVIPDFTQRXXX 530 Sbjct: 520 579 Query: 531 XXXXXXXXXXXXXXPGARRFLNQVLGMMNRLVPDGAAVKLEDL-----------RKREYH 579 Sbjct: 580 --------- 630 Query: 580 PVLAFGSYYAVGKLFIEWGLHPEAVIGRGKSQWLAACLSGELSLEEAV 627 Sbjct: 631 - 677 Score = 149 bits (377), Expect = 3e-35, Method: Compositional matrix adjust. Identities = 0/683 (0%), Positives = 0/683 (0%), Gaps = 89/683 (13%) Query: 693 GTMWLYGQDIKWRELYQHEQRNRLSLPTYAFDRQEFPVDPELFNLNHLLNRPPSGKG--G 750 Sbjct: 874 ------------ 921 Query: 751 TPADRDDIRKWFYIPAWESAALPNYEGRMLSRDAAWFIFCDPGGLGEALGDLLRQQQIRC 810 Sbjct: 922 --------- 972 Query: 811 IMVEHAEHYQQITADHYRVNPLRSEEMDRLYHSL---DAVPDHICYLWTVTSPMEPELA- 866 Sbjct: 973 - 1031 Query: 867 NIETGQQLFLHHILRLVQFLGTAAAAQ-EVHLQIVSNGLYSITQEEMLCPMKGLLLGASK 925 Sbjct: 1032 ------------- 1078 Query: 926 IIPYEYPNIKVCHVDFPLAEGDP-ARQREQARQMLREFQFEFPNKQVAYRGKSRWIEAVQ 984 Sbjct: 1079 ----- 1133 Query: 985 KPLLLASPGKVSLFRNNLVCMITXXXXXXXXXXXXXXXTQYTARLVLVGRSAFPPKSEWD 1044 Sbjct: 1134 1193 Query: 1045 QWM-NRPDDAEVARIIRTIRALEAAGAVIEVHSADISDFSAMQQVVARAEARLGPITGVL 1103 Sbjct: 1194 1253 Query: 1104 HTAGVAD-YAGVIQRRTQAMTDEVLLPKVKGTLVLDTLFR--NRRLDFFVLF-SSIGNYI 1159 Sbjct: 1254 ---- 1309 Query: 1160 YGRKFGQVGYNAANEFLDAFVHYRLQNREGFTATINWNDWAEAGMSVKAMEKNRSLHKAV 1219 Sbjct: 1310 ------ 1363 Query: 1220 ND---LQFEAEAIT--TEQGVNVFRYIMENQMNRVIVSALDLPALMEESNNISVEVILEQ 1274 Sbjct: 1364 ----- 1418 Query: 1275 XXXXXXXXXXXXXXGSSSLLTEAGLQQQIADIWSTVLGIEAIGIDEDFFALGGDSLKAIT 1334 Sbjct: 1419 --------------- 1463 Query: 1335 IVSLVFKKLGVKLPLPA-FFHKP 1356 Sbjct: 1464 1486 >RSc1810_1 [Q] COG3321 Polyketide synthase modules and related proteins Length = 1920 Score = 369 bits (946), Expect = e-101, Method: Compositional matrix adjust. Identities = 206/475 (43%), Positives = 273/475 (57%), Gaps = 31/475 (6%) Query: 1 LEIAVIGLAGRFPGAGTISEYWDNLKNGVHSVQTFSEQELIAAGVEPGLAAKAEYVKAKG 60 L IAVIG R P A I +W L +G + F ++L AG++P L ++ YV A Sbjct: 17 LPIAVIGAGCRMPRADDIFAFWHRLADGEDLIARFDARQLADAGIDPALLSRPGYVPAAA 76 Query: 61 YLEAGHCFDARFFDYTPLEAELMDPQMKVFHECIWXXXXXXXXXXXXXQQLIGLFAGASP 120 +E F+ FF Y+ EAE +DPQ ++F C W + A P Sbjct: 77 VIEQADRFEWSFFGYSRQEAETIDPQQRIFLMCAWEALEMAGYPSATLE-------AACP 129 Query: 121 NHVWEGLMGLSGKSGVMGHWAA--------------SQLL--DKDYLSLRIAHKLNLKGP 164 +G+ G + + AA +LL DKDYL+ R+++KL L GP Sbjct: 130 G----ARIGVLGACKMSSYPAARIENTQEIASPRTFGRLLGNDKDYLATRVSYKLGLTGP 185 Query: 165 ALSIYTACSTSLVAVHMAAQSLLNGECDIALAGGVTVTLPEKSGYEYQEGMILSPDGKCR 224 ++++ TACS+SLVA+H+A + L +GECD+ LAGG + P++SGY ++EGMI SPDG CR Sbjct: 186 SMTVQTACSSSLVAIHLACEQLASGECDMVLAGGAGIGFPQESGYFHREGMIFSPDGLCR 245 Query: 225 AFXXXXXXXXXXXXXXXXVLKRLQDALDDGDQIYAVIKGSAVNNDGLQKTGFTAPSTIGQ 284 F +LK L AL DGD I AVI+GS+VNNDG K G+TAPS GQ Sbjct: 246 PFDAHADGTAIGNGAAVVLLKPLDRALADGDPILAVIRGSSVNNDGRAKAGYTAPSPEGQ 305 Query: 285 AEVIRTALKLAEVSPDSIDYIECHGTGTPLGDPIELEALELGYN--PERRHACALGSVKT 342 A VI AL LAEV P SI +E HGT TPLGDPIE+EAL + + CALGSVK+ Sbjct: 306 ARVIADALALAEVDPASIHLMEAHGTATPLGDPIEVEALRRAWGGPTAQTQYCALGSVKS 365 Query: 343 NIGHLDSAAGIASFIKTVLALKHNILPPSLHFQTPNPVLKVIEKGFYINDRLTEWPSKNE 402 N+GHLD+AAG+ASF+K LAL H +PPSLHF+TPNP L + F++ L WP Sbjct: 366 NLGHLDTAAGVASFLKAALALHHGQIPPSLHFETPNPALDLASSPFFVPQTLLPWPDTPT 425 Query: 403 PLRAGISAFGIGGTNAHIIVEQAPPPREASAGREW--QLLPVSAKTPSALAEIKQ 455 P RA +SAF IGGTN H I+EQAP A +LL +SA++ +AL E+ + Sbjct: 426 PRRAAVSAFAIGGTNCHAILEQAPHVAHDGAAETGLPRLLVLSARSETALRELAR 480 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.320 0.137 0.410 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 110,149,792 Number of extensions: 4594921 Number of successful extensions: 7902 Number of sequences better than 1.0e-05: 137 Number of HSP's gapped: 7467 Number of HSP's successfully gapped: 174 Length of query: 1557 Length of database: 38,378,431 Length adjustment: 120 Effective length of query: 1437 Effective length of database: 24,538,351 Effective search space: 35261610387 Effective search space used: 35261610387 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 123 (52.0 bits)