BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0489.0025.p (1943 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value AGl2311_2 [Q] COG1020 Non-ribosomal peptide synthetase modules a... 674 0.0 RSc1811_1 [Q] COG1020 Non-ribosomal peptide synthetase modules a... 561 e-159 YPO1911_2 [Q] COG1020 Non-ribosomal peptide synthetase modules a... 545 e-154 all2644_1 [Q] COG1020 Non-ribosomal peptide synthetase modules a... 522 e-147 YPO0778_1 [Q] COG1020 Non-ribosomal peptide synthetase modules a... 497 e-140 >AGl2311_2 [Q] COG1020 Non-ribosomal peptide synthetase modules and related proteins Length = 346 Score = 674 bits (1739), Expect = 0.0, Method: Compositional matrix adjust. Identities = 0/923 (0%), Positives = 0/923 (0%), Gaps = 48/923 (5%) Query: 876 RHEPFPLTNVQMAYYLGRSSHFELGGVSTHSYLEMATELDIRRLNQ-CLNTLIQRHPALH 934 + LG + S + +N + + P Sbjct: 1 MQYHRIPHSSLEVSTLGLGTMTFGEQNSEADAHAQLDYAVAQGINLIDVAEMYPVPPRPE 60 Query: 935 TVYLPDATQQILPEVPEYTICEYDLSGYTEEAKNKRITKERDRMSHHIFNPNVWPLFEIV 994 T L + S + ++ K L + + Sbjct: 61 TQGLTETYVGNWLAKHGSREKLIIASKVSGPSR--NNDKGIRPDQALDRKNIREALHDSL 118 Query: 995 AFRSSPEESLLCISFDLLIMDAYSLEILQEEIMALYADRSLQLEELSITFRDYLVGYQQM 1054 + L + + + + A ++ + + Sbjct: 119 KRLQTDYLDLYQVHWPQRPTNCFGKLGYSWTDSAPAVSLLD--TLDALAEYQRAGKIRYI 176 Query: 1055 KSGKWYLEDKEYWLQKVEDFPLAPGLPLLTQPQHVKNPYFKRKSKHYSQQHWRQLKQISQ 1114 +L + L + + + + ++ + L Sbjct: 177 GVSNETAFGVMRYLHLADKHDLPRIVTIQNPYSLLNRSFEVGLAEVSQYEGVELLAYSCL 236 Query: 1115 NHNLTPSAVLCTVYAEVLANWSNQPQFGLNLTLFNRLPLHSDVDKLIGDFTSLLLLEVRM 1174 L N + + + + Sbjct: 237 GFGTLTGKYLNGAKPAGARNTLFSRFTRYSGEQTQKAVAAYVDIARRHGLDPAQMALAFV 296 Query: 1175 NPNDSFWEKAGNIQRVLMEALAHRHFDGIDVMREISKRRALGNKALLPIVFTSALFDNGE 1234 Sbjct: 297 ----- 351 Query: 1235 DGGEAAENHGEASDGEQSTNGITQTSQVYLDNQVALIHGKMVINWDYISELFDPAVMDAM 1294 Sbjct: 352 -- 409 Query: 1295 FAQYLSRIEAILYSREEMGFPALPASDYTSIQAY----NHTEEPIPSKT--LHGLFEEAV 1348 Sbjct: 410 ---- 465 Query: 1349 HQTPYAVAIEADNLSITYKELDDRADKVAGSLRSLGVSAGDRVGVIARKEIATFINILGI 1408 Sbjct: 466 525 Query: 1409 LKSGAAYVPIDPEYPQERVDYIRNHSQCKLVL-ETDYYEKNCR--------GQHPAELQR 1459 Sbjct: 526 -- 583 Query: 1460 HNLPESLAYVIYTSGSTGNPKGVMISHQAACNTVQDINQKFQVGAADRMLGISSLCFDLS 1519 Sbjct: 584 643 Query: 1520 VYDIFGAFAAGATLVL-VKDQ-KDIRQLADTLSAQKITIWNSVPAIMDRVGSEIRAQGIY 1577 Sbjct: 644 --- 700 Query: 1578 QENLDLRLVLLSGDWIPLHLPETVKQLFPAAKLISCGGATEASIWSIYYPIDEVMPQWTS 1637 Sbjct: 701 760 Query: 1638 IPYGMPLANQQFYVLNQQMDYCPLEVSGELYIGGSGVANGYLNDPEKPSHSFI-----HH 1692 Sbjct: 761 820 Query: 1693 PELG----YIYRTGDYGVLHRDGCIEFLGRKDQQVKVGGYRIELGEVEAQLLRCGGVRHA 1748 Sbjct: 821 880 Query: 1749 VVLAADGEDKRLGAYLIPDSQSA 1771 Sbjct: 881 - 902 Score = 223 bits (569), Expect = 2e-57, Method: Compositional matrix adjust. Identities = 0/715 (0%), Positives = 0/715 (0%), Gaps = 33/715 (4%) Query: 20 SGEIPLLHLPADHSRPAFKTYRGSAEMFSIPKEQVLEIKQLAAEQEATLYMVLFAVWNIL 79 + + + + +R E + Sbjct: 199 PRIVTIQNPYSLLNRSFEVGLAE--VSQYEGVELLAYSCLGFGTLTGKYLNGAKPA---G 253 Query: 80 LAKLSDQEEIIVGVPTSGRN--HSDIEHVIGMFVNTLPIKSRISAKLTFAEILHAMKANI 137 + + + + + A L Sbjct: 254 ARNTLFSRFTRYSGEQTQKAVAAYVDIARRHGLDPAQMALAFVRRQPFVASTLLGATTMD 313 Query: 138 SNALEHQDYPFEDLVSQLQITRDFGRNPLFDVMFXXXXXXXXXXXXXXXXXXELQMKPYP 197 Sbjct: 314 ---- 369 Query: 198 YTTTTSRFDLTLDGEERAGELVFTLEYATDLFTRETVMRLIRYFRTILLEVLKHPAQKTG 257 Sbjct: 370 429 Query: 258 LIHLPDNQETDRLLNRFNQTAGEYPEHLTVHQLFAARVKEHPHQAAVTFRNQSITYDELN 317 Sbjct: 430 -- 487 Query: 318 XXXXXXXXXXXXXGIGPDQIVALITTRSVDMXXXXXXXXXXXXXXXPIDPGLPANRIAYM 377 Sbjct: 488 547 Query: 378 LDDAGVQVILTNTSVENQGNRIVLDMRSLGLDHGAPLPVPPVHSSRNLAYCMYTSGTTGL 437 Sbjct: 548 ----- 602 Query: 438 PKGILVEHRSLLNFFSAISDVLSFGKGETFLSLTTVSFDIFWLESILPLLAGYQLVIADE 497 Sbjct: 603 662 Query: 498 LQQKDVHALLALVKQAEISVMQTTPSRXXXXXXXXXXXXXXXXXRYLLIGGEPLPQALAE 557 Sbjct: 663 722 Query: 558 QARSILPGGRIFNLYGPTETTIWSTAQEVTAG-----PVNIGKPLKNTQVYILNDELLLQ 612 Sbjct: 723 782 Query: 613 PIGVPGILYIGGHGVVRGYQNNPELTAQRFIDNPYRPGEQ-------IYCTGDIARWTEE 665 Sbjct: 783 842 Query: 666 GTIEYLGRADFQVKIRGYRIELAEIEQQLDTHPAIEKSVVRAQRDDQDEPMLVAY 720 Sbjct: 843 --- 894 Score = 99.0 bits (245), Expect = 6e-20, Method: Compositional matrix adjust. Identities = 0/225 (0%), Positives = 0/225 (0%), Gaps = 23/225 (10%) Query: 1704 YGVLHRDGCIEFLGRKDQQVKVGGYRIELGEVEAQLLRCGGVRH---AVVLAADGEDKRL 1760 Sbjct: 1058 ----- 1112 Query: 1761 ----GAYLIPDSQSADQAA-------FINEVRARIAKVLPDYMIPHYFVVLEQFPLTANG 1809 Sbjct: 1113 1172 Query: 1810 KMDVQALLKLQPAGNKQTSAYTAPRNDVEERIVNIFKELLEADQVGTLDNFFEMGINSVQ 1869 Sbjct: 1173 ---- 1228 Query: 1870 IAMINNKLKQEFQKEIPLLTLFEYANIHALAGYLSGNDQNEPDDV 1914 Sbjct: 1229 1273 Score = 85.9 bits (211), Expect = 5e-16, Method: Compositional matrix adjust. Identities = 0/121 (0%), Positives = 0/121 (0%), Gaps = 11/121 (9%) Query: 732 LREFLLKFLPAYMIPQHFMEIGKIPLMISGKLDVKALPPVTVTLVQPG----ETRKPQDE 787 Sbjct: 1143 ------- 1195 Query: 788 VEEKLLEIWKKVLRIGDTGVQDGFFEMGGNSIQIMQLVYEINKCFPVSFQFTHFIERQTI 847 Sbjct: 1196 1255 Query: 848 E 848 Sbjct: 1256 1256 >RSc1811_1 [Q] COG1020 Non-ribosomal peptide synthetase modules and related proteins Length = 211 Score = 561 bits (1446), Expect = e-159, Method: Compositional matrix adjust. Identities = 0/954 (0%), Positives = 0/954 (0%), Gaps = 60/954 (6%) Query: 867 PFIAADPANRHEPFPLTNVQMAYYLGRSSHFELGGVSTHSYLE-MATELDIRRLNQCLNT 925 Sbjct: 233 -- 290 Query: 926 LIQRHPALHTVYLPDATQQILPEVPEYTICEYDLSGYTEEAKNKRITKERDRMSHHIFNP 985 Sbjct: 291 350 Query: 986 NVWPLFEIVAFRSSPEESLLCISFDLLIMDAYSLEILQEEIMALYADRSLQLEELSITFR 1045 Sbjct: 351 410 Query: 1046 DYLVGYQQMKSGKWYLEDKEYWLQKVEDFPLAPGLPLLTQPQHVKNPYFKRKSKHYSQQH 1105 Sbjct: 411 470 Query: 1106 WRQLKQISQNHNLTPSAVLCTVYAEVLANWSNQPQFGLNLTLFNRLPLHSDVDKLIGDFT 1165 Sbjct: 471 530 Query: 1166 SLLLLEVRMNPNDSFWEKAGNIQRVLMEALAHRHFDGIDVMREISKRRA-----LGNKAL 1220 Sbjct: 531 590 Query: 1221 LPIVFTSALFDNGEDGGEAAENHGEASDGEQSTNGITQTSQVYLDNQVALIHGKMVINWD 1280 Sbjct: 591 ------ 644 Query: 1281 YISELFDPAVMDAMFAQYLSRIEAIL--YSREEMGFPA-LPASDYTSIQAYNHTEEPIPS 1337 Sbjct: 645 704 Query: 1338 KTLH-GLFEEAVHQTPYAVAIEADNLSITYKELDDRADKVAGSLRSLGVSAGDRVGVIAR 1396 Sbjct: 705 - 763 Query: 1397 KEIATFINILGILKSGAAYVPIDPEYPQERVDYIRNHSQCK--LVLETDYYEKNCRG--- 1451 Sbjct: 764 823 Query: 1452 ------QHPA---------ELQRHNLP---ESLAYVIYTSGSTGNPKGVMISHQAACNTV 1493 Sbjct: 824 883 Query: 1494 QDINQKFQVGAADRMLGISSLCFDLSVYDIFGAFAAGATLVLVKDQKDIRQLA---DTLS 1550 Sbjct: 884 - 942 Query: 1551 AQKITIWNSVPAIM----DRVGSEIRAQGIYQENLDLRLVLLSGDWIPLHLPETVKQLFP 1606 Sbjct: 943 ----- 997 Query: 1607 AAKLISCGGATEASIWSIYYPIDEVMPQWTSIPYGMPLANQQFYVLNQQMDYCPLEVSGE 1666 Sbjct: 998 1057 Query: 1667 LYIGGSGVANGYLNDPEKPSHSFIHHPELG-YIYRTGDYGVLHRDGCIEFLGRKDQQVKV 1725 Sbjct: 1058 1117 Query: 1726 GGYRIELGEVEAQLLRCGGVR--HAVVLAADGEDKRLGAYLIPD--SQSADQAA 1775 Sbjct: 1118 1171 Score = 169 bits (429), Expect = 3e-41, Method: Compositional matrix adjust. Identities = 0/707 (0%), Positives = 0/707 (0%), Gaps = 39/707 (5%) Query: 22 EIPLLHLPADHSRPAFKTYRGSAEMFSIPKEQVLEIKQLAAEQEATLYMVLFAVWNILLA 81 Sbjct: 444 ----- 498 Query: 82 KLSDQEEIIVGVPTSGRN--HSDIEHVIGMFVNTLPIKSRISAKLTFAEILHAMKANISN 139 Sbjct: 499 558 Query: 140 ALEHQDYPFEDLVSQLQITR--DFGRNPLFDVMFXXXXXXXXXXXXXXXXXXELQMKPYP 197 Sbjct: 559 618 Query: 198 YTTTTSRFDLTLDGEERAGELVFTLEYATDLFTRETVMRLIRYFRTILLEVLKHPA--QK 255 Sbjct: 619 678 Query: 256 TGLIHLPDNQETDRLLNRFNQTAGEYPEHLTVHQLFAARVKEHPHQAAVTFRNQSITYDE 315 Sbjct: 679 --- 735 Query: 316 LNXXXXXXXXXXXXXGIGPDQIVALITTRSVDMXXXXXXXXXXXXXXXPIDPGLPANRIA 375 Sbjct: 736 795 Query: 376 YMLDDAGVQVILTNTS--------------VENQGNRIVLDMRSLGLDHGAPLPVPPVHS 421 Sbjct: 796 855 Query: 422 SRNLAYCMYTSGTTGLPKGILVEHRSLLNFFSAISDVLSFGKGETFLSLTTVSFDIFWLE 481 Sbjct: 856 --- 912 Query: 482 SILPLLAGYQLVIADELQQKDVHALLALVKQAEISVMQTTPSRXXXXXXXXXXXXXX--X 539 Sbjct: 913 972 Query: 540 XXRYLLIGGEPLPQALAEQARSILPGGRIFNLYGPTETTIWSTAQEV-----TAGPVNIG 594 Sbjct: 973 1032 Query: 595 KPLKNTQVYILNDELLLQPIGVPGILYIGGHGVVRGYQNNPELTAQRFIDNPYRPGEQIY 654 Sbjct: 1033 - 1091 Query: 655 CTGDIARWTEEGTIEYLGRADFQVKIRGYRIELAEIEQQLDTHPAIE 701 Sbjct: 1092 1138 Score = 62.8 bits (151), Expect = 6e-09, Method: Compositional matrix adjust. Identities = 0/135 (0%), Positives = 0/135 (0%), Gaps = 10/135 (7%) Query: 716 MLVAYYTAARTVSGAELREFLLKFLPAYMIPQHFMEIGKIPLMISGKLDVKALP---PVT 772 Sbjct: 1558 1617 Query: 773 VTLVQPGETRK-PQDEVEEKLLEIWKKVLRIG-DT-GVQDGFFEMGGNSIQIMQLVYEIN 829 Sbjct: 1618 1677 Query: 830 KCF----PVSFQFTH 840 Sbjct: 1678 1692 >YPO1911_2 [Q] COG1020 Non-ribosomal peptide synthetase modules and related proteins Length = 346 Score = 545 bits (1404), Expect = e-154, Method: Compositional matrix adjust. Identities = 0/912 (0%), Positives = 0/912 (0%), Gaps = 35/912 (3%) Query: 879 PFPLTNVQMAYYLGRSSHFELGGVSTHSYLEMATE-LDIRRLNQCLNTLIQRHPALHTVY 937 + LG + S + + + P T Sbjct: 4 HRIPHSSLEVSTLGLGTMTFGEQNSEADAHAQLDYAVAQGINLIDVAEMYPVPPRPETQG 63 Query: 938 LPDATQQILPEVPEYTICEYDLSGYTEEAKNKRITKERDRMSHHIFNPNVWPLFEIVAFR 997 L + S + ++N D+ Sbjct: 64 LTETYVGNWLAKHGSREKLIIASKVSGPSRNNDKGIRPDQALDRKNIREALHDSLKRLQT 123 Query: 998 SSPEESLLCISFDLLIMDAYSLEILQEEIMALYADRSLQLEELSITFRDYLVGYQQMKSG 1057 + + + A+ +L Sbjct: 124 DYLDLYQVHWPQRPTNCFGKLGYSWTDSAPAVSLLDTLDALAEYQRAGKIRY-IGVSNET 182 Query: 1058 KWYLEDKEYWLQKVEDFPLAPGLPLLTQPQHVKNPYFKRKSKHYSQQHWRQLKQISQNHN 1117 + + + K + + + S++ + Sbjct: 183 AFGVMRYLHLADKHDLPRIVTIQNPYSLLNRSFEVGLAEVSQYEGVELLAYSCLGFGTLT 242 Query: 1118 LTPSAVLCTVYAEVLANWSNQPQFGLNLTLFNRLPLHSDVDKLIGDFTSLLLLEVRMNPN 1177 A G + + L R Sbjct: 243 GKYLNGAKPAGARNTLFSRFTRYSGEQTQKAVAAYVDIARRHGLDPAQMALAFVRRQP-F 301 Query: 1178 DSFWEKAGNIQRVLMEALAHRHFDGIDVMREISKRRALGNKALLPIVFTSALFDNGEDGG 1237 + L + H + + + + Sbjct: 302 VASTLLGATTMDQLKTNIESLHLELSEDVLAEIEAVHQVYTY-------- 353 Query: 1238 EAAENHGEASDGEQSTNGITQTSQVYLDNQVALIHGKMVINWDYISELFDPAVMDAMFAQ 1297 Sbjct: 354 - 412 Query: 1298 YLSRIEAILYSREEMGFP---ALPASDYTSIQAYNHTEEPIPSKTLH-GLFEEAVHQTPY 1353 Sbjct: 413 - 471 Query: 1354 AVAIEADNLSITYKELDDRADKVAGSLRSLGVSAGDRVGVIARKEIATFINILGILKSGA 1413 Sbjct: 472 531 Query: 1414 AYVPIDPEYPQERVDYIRNHSQCKLVLETDYYEKNCRGQHPAELQRHNL----------- 1462 Sbjct: 532 591 Query: 1463 -PESLAYVIYTSGSTGNPKGVMISHQAACNTVQDINQKFQVGAADRMLGISSLCFDLSVY 1521 Sbjct: 592 651 Query: 1522 DIFGAFAAGATLVLVKD--QKDIRQLADTLSAQKITIWNSVPAIMDRVGSEIRA-QGIYQ 1578 Sbjct: 652 711 Query: 1579 ENLDLRLVLLSGDWIPLHLPETVKQLFPAAKLISCGGATEASIWSIYYPIDEVMPQWTSI 1638 Sbjct: 712 -- 769 Query: 1639 PYGMPLANQQFYVLNQQMDYCPLEVSGELYIGGSGVANGYLNDPEKPSHSFIHHPELGYI 1698 Sbjct: 770 - 828 Query: 1699 YRTGDYGVLHRDGCIEFLGRKDQQVKVGGYRIELGEVEAQLLRCGGVRHAVVLAADGEDK 1758 Sbjct: 829 888 Query: 1759 RLGAYLIPDSQS 1770 Sbjct: 889 900 Score = 184 bits (467), Expect = 1e-45, Method: Compositional matrix adjust. Identities = 0/718 (0%), Positives = 0/718 (0%), Gaps = 26/718 (3%) Query: 14 YWLETFSGEIPLLHLPADHSRPAFKTYRGSAEMFSIPKEQVLEIKQLAAEQEATLYMVLF 73 + + + + E + Sbjct: 191 HLADKHDLPRIVTIQNPYSLLNRSFEVGLAEVSQYEGVELLAYSCLGFGTLTGKYLNGAK 250 Query: 74 AVWNILLAKLSDQEEIIVGVPTSGRN--HSDIEHVIGMFVNTLPIKSRISAKLTFAEILH 131 + H + L R + Sbjct: 251 PAGARNTLFSRFTRYSGEQTQKAVAAYVDIARRHGLDPAQMALAFVRRQPFV-ASTLLGA 309 Query: 132 AMKANISNALEHQDYPFEDLVSQLQITRDFGRNPLFDVMFXXXXXXXXXXXXXXXXXXEL 191 + +E + V Sbjct: 310 TTMDQLKTNIESLHLELSEDVLAEIEAVHQVYTY--- 366 Query: 192 QMKPYPYTTTTSRFDLTLDGEERAGELVFTLEYATDLFTRETVMRLIRYFRTILLEVLKH 251 Sbjct: 367 --- 423 Query: 252 PA--QKTGLIHLPDNQETDRLLNRFNQTAGEYPEHLTVHQLFAARVKEHPHQAAVTFRNQ 309 Sbjct: 424 --- 480 Query: 310 SITYDELNXXXXXXXXXXXXXGIGPDQIVALITTRSVDMXXXXXXXXXXXXXXXPIDPGL 369 Sbjct: 481 540 Query: 370 PANRIAYMLDDAGVQVILTNTSVENQGNRIVLDMRSLGLDHGAPLPVPPVHSSRNLAYCM 429 Sbjct: 541 600 Query: 430 YTSGTTGLPKGILVEHRSLLNFFSAISDVLSFGKGETFLSLTTVSFDIFWLESILPLLAG 489 Sbjct: 601 660 Query: 490 YQLVIADELQQKDVHALLALVKQAEISVMQTTPS--RXXXXXXXXXXXXXXXXXRYLLIG 547 Sbjct: 661 720 Query: 548 GEPLPQALAEQARSILPGGRIFNLYGPTETTIWSTAQEVTAGPVN-----IGKPLKNTQV 602 Sbjct: 721 780 Query: 603 YILNDELLLQPIGVPGILYIGGHGVVRGYQNNPELTAQRFIDNPYRPGEQIYCTGDIARW 662 Sbjct: 781 --- 837 Query: 663 TEEGTIEYLGRADFQVKIRGYRIELAEIEQQLDTHPAIEKSVVRAQRDDQDEPMLVAY 720 Sbjct: 838 -- 893 Score = 68.2 bits (165), Expect = 1e-10, Method: Compositional matrix adjust. Identities = 0/140 (0%), Positives = 0/140 (0%), Gaps = 7/140 (5%) Query: 1779 EVRARIAKVLPDYMIPHYFVVLEQFPLTANGKMDVQALLKLQPAGNKQTSAYTAPRNDVE 1838 Sbjct: 1241 1300 Query: 1839 ERIVNIFKELLEADQVGTLDNFFEMGINSVQIAMINNKLKQEFQKEIPLLTLFEYANIHA 1898 Sbjct: 1301 - 1359 Query: 1899 LAGYLSGNDQNEPDDVPQEQ 1918 Sbjct: 1360 ------ 1373 Score = 63.2 bits (152), Expect = 4e-09, Method: Compositional matrix adjust. Identities = 0/143 (0%), Positives = 0/143 (0%), Gaps = 11/143 (7%) Query: 731 ELREFLLKFLPAYMIPQHFMEIGKIPLMISGKLDVKALPPV-TVTLVQPGETRKPQDEVE 789 Sbjct: 1241 1300 Query: 790 EKLLEIWKKVLRIGDTGVQDGFFEMGGNSIQIMQLVYEINKC---FPVSFQFTHFIERQT 846 Sbjct: 1301 ------ 1354 Query: 847 IERIADFIKEAIQEERKEELPFI 869 Sbjct: 1355 - 1376 >all2644_1 [Q] COG1020 Non-ribosomal peptide synthetase modules and related proteins Length = 346 Score = 522 bits (1344), Expect = e-147, Method: Compositional matrix adjust. Identities = 0/874 (0%), Positives = 0/874 (0%), Gaps = 44/874 (5%) Query: 14 YWLETFSGEIPLLHLPADHSRPAFKTYRGSAEMFSIPKEQVLEIKQLAAEQEATLYMVLF 73 G + G+ + + + + Sbjct: 211 LNRSFEVGLAEVSQYEGVELLAYSCLGFGTLTGKYLNGAKPAGARNTLFSRFTRYSGEQT 270 Query: 74 AVWNILLAKLSDQEEIIVGVPTSGRNHSDIEHVIGMFVNTLPIKSRISAKLTFAEILHAM 133 ++ + + + T + + + + E+ + Sbjct: 271 QKAVAAYVDIARRHGLDPAQMALAFVRRQPFVASTLLGATTMDQLKTNIESLHLELSEDV 330 Query: 134 KANISNALEHQDYPFEDLVSQLQITRDFGRNPLFDVMFXXXXXXXXXXXXXXXXXXELQM 193 Sbjct: 331 ----- 385 Query: 194 KPYPYTTTTSRFDLTLDGEERAGELVFTLEYATDLFTRETVMRLIRYFRTILLEVLKHPA 253 Sbjct: 386 445 Query: 254 QKTGLIHLPDNQETDRLLNRFNQTAGEYPEHLTVHQLFAARVKEHPHQAAVTFRNQSITY 313 Sbjct: 446 -- 503 Query: 314 DELNXXXXXXXXXXXXXGIGPDQIVALITTRSVDMXXXXXXXXXXXXXXXPIDPGLPANR 373 Sbjct: 504 563 Query: 374 IAYMLDDAGVQVILTNTSVENQGNRIVLDMRSLG------LDHGAPL---PVPPVHSSRN 424 Sbjct: 564 -- 621 Query: 425 ----------LAYCMYTSGTTGLPKGILVEHRSLLNFFSAISDVLSFGKGETFLSLTTVS 474 Sbjct: 622 681 Query: 475 FDIFWLESILPLLAGYQLVIADELQQKDVHALLALVKQAEISVMQTTPSRXXXXXXXXXX 534 Sbjct: 682 741 Query: 535 XXXXXXXRYLLIGGEPLPQALAEQARSILPGGRIFNLYGPTETTIWSTAQEVTAG-PVNI 593 Sbjct: 742 ----- 796 Query: 594 GKPLKNTQVYILNDELLLQPIGVPGILYIGGHGVVRGYQNNPELTAQRFIDNPYRPGEQ- 652 Sbjct: 797 856 Query: 653 -----IYCTGDIARWTEEGTIEYLGRADFQVKIRGYRIELAEIEQQLDTHPAIEKSVVRA 707 Sbjct: 857 916 Query: 708 QRDDQDEPMLVAYYTA-ARTVSGAELREFLLKFLPAYMIPQHFMEIGKIPLMISGKLDVK 766 Sbjct: 917 976 Query: 767 ALPPVTVTLVQPGETRKPQDEVEEKLLEIWKKVLRIGDTGVQDGFFEMGGNSIQIMQLVY 826 Sbjct: 977 --- 1033 Query: 827 EINKCFPVSFQFTHFIERQTIERIADFIKEAIQE 860 Sbjct: 1034 1067 Score = 411 bits (1056), Expect = e-114, Method: Compositional matrix adjust. Identities = 0/1094 (0%), Positives = 0/1094 (0%), Gaps = 96/1094 (8%) Query: 861 ERKEELPFIAADPANRHEPFPLTNVQMAYYLGRSSHFELGGVSTHSYLEMATELDIRRLN 920 + L + + + + + + L Sbjct: 7 PHSSLEVSTLGLGTMTFG-EQNSEADAHAQLDYAVAQGINLIDVAEMYPVPPRPETQGLT 65 Query: 921 QCLNTLIQRHPALHTVY--LPDATQQILPEVPEYTICEYDLSGYTEEAKNKRITKERDRM 978 + + + EA + + + + Sbjct: 66 ETYVGNWLAKHGSREKLIIASKVSGPSRNNDKGIRPDQALDRKNIREALHDSLKRLQTDY 125 Query: 979 SHHIFNPNVWPLFEIVAFRSSPEESLLCISFDLLIMDAYSLEILQEEIMALYADRSLQLE 1038 L +DA + +I + Sbjct: 126 LDLYQVHWPQRPTNCFGKLGYSWTDSAPAVSLLDTLDALAEYQRAGKIRYIGVSNET--A 183 Query: 1039 ELSITFRDYLVGYQQMKSGKWYLEDKEYWLQKVEDFPLAPGLPLLTQPQHVKNPYFKRKS 1098 + + + + + + + Sbjct: 184 FGVMRYLHLADKHDLPRIVTIQNPYSLLNRSFEVGLAEVSQYEGVELLAYSCLGFGTLTG 243 Query: 1099 KHYSQQHWRQLKQISQNHNLTPSAVLCTVYAEVLANWSNQPQFGLNLTLFNRLPLHSDVD 1158 K+ + + + S + + + + Sbjct: 244 KYLNGAKPAGARNTLFSRFTRYSGEQTQKAVAAYVDIARRHGLDPAQMALAFV--RRQPF 301 Query: 1159 KLIGDFTSLLLLEVRMNPNDSFWEKAGNIQRVLMEALAHRHFDGIDVMREISKRRALGNK 1218 Sbjct: 302 361 Query: 1219 ALLPIVFTSALFDNGEDGGEAAENHGEASDGEQSTNGITQTSQVYLDNQVALIHGKMVIN 1278 Sbjct: 362 -------- 413 Query: 1279 WDYISELFDPAVMDAMFAQYLSRIEAILYSREEM--GFPALPASDYTSIQAYNHTEEPIP 1336 Sbjct: 414 473 Query: 1337 SKTLHGLFEEAVHQTPYAVAIEADNLSITYKELDDRADKVAGSLRSLGVSAGDRVGVIAR 1396 Sbjct: 474 533 Query: 1397 KEIATFINILGILKSGAAYVPIDPEYPQERVDYIRNHSQCKLVLETDYYEKN-------- 1448 Sbjct: 534 593 Query: 1449 ---------CRGQHPAELQRHNL------------PESLAYVIYTSGSTGNPKGVMISHQ 1487 Sbjct: 594 653 Query: 1488 AACNTVQDINQKFQVGAADRMLGISSLCFDLSVYDIFGAFAAGATLVLVKDQK--DIRQL 1545 Sbjct: 654 713 Query: 1546 ADTLSAQKITIWNSVPAIMDRVGSEIRAQGIYQENLDLRLVLLSGDWIPLHLPETVKQLF 1605 Sbjct: 714 ------------ 761 Query: 1606 PAAKLISCG-------GATEASIWSI--YYPIDEVMPQWTSIPYGMPLANQQFYVLNQQM 1656 Sbjct: 762 --------- 812 Query: 1657 DYCPLEVSGELYIGGSGVANGYLNDPEKPSHSFIH--------HPELGYIYRTGDYGVLH 1708 Sbjct: 813 872 Query: 1709 RDGCIEFLGRKDQQVKVGGYRIELGEVEAQLLRCGGVRHAVVLAADGE--DKRLGAYLIP 1766 Sbjct: 873 932 Query: 1767 DSQSADQAAFINEVRARIAKVLPDYMIPHYFVVLEQFPLTANGKMDVQALLKLQPAGNKQ 1826 Sbjct: 933 -------- 984 Query: 1827 TSAYTAPRNDVEERIVNIFKELLEADQVGTLDNFFEMGINSVQIAMINNKLKQEFQKEIP 1886 Sbjct: 985 1044 Query: 1887 LLTLFEYANIHALA 1900 Sbjct: 1045 1058 >YPO0778_1 [Q] COG1020 Non-ribosomal peptide synthetase modules and related proteins Length = 346 Score = 497 bits (1279), Expect = e-140, Method: Compositional matrix adjust. Identities = 0/934 (0%), Positives = 0/934 (0%), Gaps = 71/934 (7%) Query: 878 EPFPLTNVQMAYYLGRSSHFELGGVSTHSYLEM-ATELDIRRLNQCLNTLIQRHPALHTV 936 + + + + ++ A+H Sbjct: 281 ARRHGLDPAQMALAFVRRQPFVASTLLGATTMDQLKTNIESLHLELSEDVLAEIEAVH-Q 339 Query: 937 YLPDATQQILPEVPEYTICEYDLSGYTEEAKNKRITKERDRMSHHIFNPNVWPLFEIVAF 996 Sbjct: 340 399 Query: 997 RSSPEESLLCISFDLLIMDAYSLEILQEEIMALYADRSLQLEELSITFRDYLVGYQQMKS 1056 Sbjct: 400 ---- 455 Query: 1057 GKWYLEDKEYWLQK-VEDFPLAPGLPLLTQPQHVKNPYFKRKSKHYSQQHWRQLKQISQN 1115 Sbjct: 456 515 Query: 1116 HNLTPSAVLCTVYAEVLANWSNQPQFGLNLTLFNRLPLHSDVDKLIGDFTSLLLLEVRMN 1175 Sbjct: 516 575 Query: 1176 PNDSFWEKAGNIQRVLMEALAHRHFDGIDVMREISKRRALGNKALLPIVFTSALFDNGED 1235 Sbjct: 576 ---------- 625 Query: 1236 GGEAAENHGEASDGEQSTNG----ITQTSQVYLDNQVALIHGKMVINWDYISELFDPAVM 1291 Sbjct: 626 ------ 679 Query: 1292 DAMFAQYLSRIEAILYSREEMGFPALPASDYTSIQAYNHTEEPIP--------SKTLHGL 1343 Sbjct: 680 --- 736 Query: 1344 FEEAVHQTPYAVAIEADNLSITYKELDDRADKVAGSLRSLGVSAGDRVGVIARKEIATFI 1403 Sbjct: 737 - 795 Query: 1404 NILGILKSGAAYVPIDPEYPQERVDYIRNHSQCKLVLETDYYEKNC-------RGQHPAE 1456 Sbjct: 796 855 Query: 1457 LQRHNL-----------------PESLAYVIYTSGSTGNPKGVMISHQAACNTVQDINQK 1499 Sbjct: 856 915 Query: 1500 FQVGAADRMLGISSLCFDLSVYDIFGAFAAGATLVL--VKDQKDIRQLADTLSAQKITIW 1557 Sbjct: 916 975 Query: 1558 NSVPAIMDR--VGSEIRAQGIYQENLDLRLVLLSGDWIPLHLPETVKQLFPAAKLISCGG 1615 Sbjct: 976 --- 1032 Query: 1616 ATEASIWSIYYPIDEVMPQWTSIPYGMPLANQQFYVLNQQMDYCPLEVSGELYIGGSGVA 1675 Sbjct: 1033 1092 Query: 1676 NGYLNDPEKPSHSFIHHPELGYIYRTGDYGVLHRDGCIEFLGRKDQQVKVGGYRIELGEV 1735 Sbjct: 1093 - 1151 Query: 1736 EAQLLRCGGVRHAVVLAADGEDKRLGAYLIPDSQ 1769 Sbjct: 1152 1185 Score = 136 bits (342), Expect = 4e-31, Method: Compositional matrix adjust. Identities = 0/458 (0%), Positives = 0/458 (0%), Gaps = 55/458 (12%) Query: 283 EHLTVHQLFAARVKEHPHQAAV-------TFRNQSITYDELNXXXXXXXXXXXXXGI--- 332 Sbjct: 729 788 Query: 333 -GPDQIVALITTRSVDMXXXXXXXXXXXXXXXPIDPGLPANRIAYMLDDAGVQVILTNTS 391 Sbjct: 789 ------------ 836 Query: 392 VENQGNRIVLDMRSLGLDHGAPLP-VPPVHSSRNLA----------------YCMYTSGT 434 Sbjct: 837 ----- 891 Query: 435 TGLPKGILVEHRSLLNFFSAISDVLSFGKGETFLSLTTVSFDIFWLESILPLLAGYQLVI 494 Sbjct: 892 951 Query: 495 ADELQQKDVHALLALVKQAEISVMQTTPS--RXXXXXXXXXXXXXXXXXRYLLIGGEPLP 552 Sbjct: 952 1011 Query: 553 QALAEQARSILPGGRIFNLYGPTETTIWSTAQEVTAGP-----VNIGKPLKNTQVYILND 607 Sbjct: 1012 1071 Query: 608 ELLLQPIGVPGILYIGGHGVVRGYQNNPELTAQRFIDNPYRPGEQIYCTGDIARWTEEGT 667 Sbjct: 1072 --- 1128 Query: 668 IEYLGRADFQVKIRGYRIELAEIEQQLDTHPAIEKSVV 705 Sbjct: 1129 1166 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.319 0.137 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 140,092,764 Number of extensions: 5916689 Number of successful extensions: 13092 Number of sequences better than 1.0e-05: 252 Number of HSP's gapped: 11992 Number of HSP's successfully gapped: 471 Length of query: 1943 Length of database: 38,378,431 Length adjustment: 121 Effective length of query: 1822 Effective length of database: 24,423,017 Effective search space: 44498736974 Effective search space used: 44498736974 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 123 (52.0 bits)