BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0489.0013.p (1426 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value all2646 [Q] COG3321 Polyketide synthase modules and related prot... 589 e-167 all2635 [Q] COG3321 Polyketide synthase modules and related prot... 536 e-151 AGl2313 [Q] COG3321 Polyketide synthase modules and related prot... 470 e-132 ML2353_1 [Q] COG3321 Polyketide synthase modules and related pro... 447 e-125 AGl2329 [Q] COG3321 Polyketide synthase modules and related prot... 444 e-124 >all2646 [Q] COG3321 Polyketide synthase modules and related proteins Length = 1488 Score = 589 bits (1519), Expect = e-167, Method: Compositional matrix adjust. Identities = 304/650 (46%), Positives = 416/650 (64%), Gaps = 18/650 (2%) Query: 4 KIAIIGLACRVPGADTPAAFWHQIVNGVESIRTFKDEELTASGISADILNHPQYVKRGAV 63 +IAIIG+ + PGA+ +W + NGVESI DE++ +G+ L HP YVKR A+ Sbjct: 8 EIAIIGINGKFPGANNLEEYWQNLRNGVESITNLTDEQIQKNGVDPTQLKHPNYVKRQAI 67 Query: 64 IENADCFDAGFFRYTAKDAEITDPQHRAFLECAWEALEDAGCVQDLEKYPVGVYASSCIS 123 I+N + FDA FF + ++AEI DPQHR FLECAW ALEDAG + +GVYA + ++ Sbjct: 68 IDNIEYFDAEFFGFNPREAEILDPQHRLFLECAWTALEDAGYNPENYTGAIGVYAGAAMN 127 Query: 124 SYVLNLYSDPELMGRLGHVQIGIGNEKDFLASKVSYKLGLRGPSVNVQTACSSSLVAVHM 183 +Y+LNL ++P++ ++ Q+ + N+KDFL ++VSYKL LRGPS+++QTACS+SLVAVH+ Sbjct: 128 NYLLNLITNPQIQNQISRYQLFLSNDKDFLTTRVSYKLNLRGPSLDIQTACSTSLVAVHV 187 Query: 184 ASQSLLNGECDLALAGGVTIRSEQRAGYMYQKEGMVSPDGHCRVFDKDSKGTVFGNGLGI 243 A QSLL+GECD+ALAGGV++ + GY+YQ+ G+ SPDGHCR FD D++GT+ G+GLGI Sbjct: 188 ACQSLLSGECDIALAGGVSL--AKATGYLYQEGGIYSPDGHCRAFDADAQGTIAGSGLGI 245 Query: 244 VVLKRLADAVRDRDNIQAVICGTAVNNDGDHKIGFTAPSPVGQAQVIHEALSVAGVAPRE 303 VVLKRL +A+ DRD I AVI G+A+NNDG K+ +TAP QA VI A ++AGV P + Sbjct: 246 VVLKRLQEAIEDRDYIHAVIKGSAINNDGGLKVSYTAPRIDTQAAVIRAAQALAGVEPAD 305 Query: 304 ISYIETHGTGTELGDAIEIKALKEVFQAETGPAQFCAIGSVKPNIGHLDTAAGIIGLIKT 363 ISYIETHGTGT LGD IEI AL + F+A T FCAI SVK NIGHLD AAGI LIKT Sbjct: 306 ISYIETHGTGTALGDPIEIAALTQAFRAGTEKTGFCAISSVKTNIGHLDAAAGIASLIKT 365 Query: 364 TLAMKNQVIPVCINHETPDPKLSLEDSPFYVNTASRPWKEVSAAPKAGVSSFGIGGTNAH 423 LA+K+Q IP ++ + P+P++ +PFYVNT W+ +AGVSSFGIGGTNAH Sbjct: 366 VLALKHQQIPPNLHFQQPNPQIDFSQTPFYVNTNLVDWETDKTPRRAGVSSFGIGGTNAH 425 Query: 424 IILEEAP---SIASDASAKQNHVFLFSAKTLKSLEDTCRNMADFFGNHSTLHPADVAYTL 480 +ILEEAP I + + SAK+ K+LE+ N+A + H + AD+AYTL Sbjct: 426 VILEEAPIKFKIQNSKFKINYQMLCLSAKSEKALEEATINLATYLQQHPQFNLADIAYTL 485 Query: 481 QTGRKHFPYRKMVVSSSLEEAAQWLRTGSSQTECKGREEVPVAFFFPAEQRDMLRIGYEL 540 GR+HF YR+MV+ + EEAAQ L + T + +AF FP + L +G EL Sbjct: 486 HIGRQHFAYRRMVLCQTTEEAAQILEKETKYTHTNSEKSPSIAFMFPGQGSHYLNMGKEL 545 Query: 541 YQKETRFASIIDTYLSNERILHTLAGLDLQQILAGSR----------HGNQERLYTVLGQ 590 Y+ E F ID E + H L GLDL IL + + +Y Sbjct: 546 YETEAIFREQIDH--CCELLQHDL-GLDLLSILFETESIPSPQSPVPSPQSQTIYAQPAL 602 Query: 591 FIYQCALADYLVTLGIRKEVLIAEGNGVLPAVYVSGALSMNDLIRIILIR 640 FI + ALA ++ GI+ + +I G ++G S+ D+++++ +R Sbjct: 603 FIIEYALAKLWISWGIQPQAMIGHSLGEYVVATLAGVFSLPDVLKLVALR 652 Score = 218 bits (556), Expect = 4e-56, Method: Compositional matrix adjust. Identities = 171/727 (23%), Positives = 332/727 (45%), Gaps = 71/727 (9%) Query: 651 QSLLAIELASLLKILPVQTPEAEMLAG--GLRVSEEMLRDEEFWLSC--GPASDWPQAPS 706 +S++ +A+ KI +QTP+ ++ G ++ E D +W++ P Sbjct: 731 ESMITPFIAAFQKI-TLQTPKIPFISNVTGTWITAEQATDPHYWVNHLRQPVQFATGIKE 789 Query: 707 LPEQENRLLIKIG----MESGTDGALKGMGVVSLLRQQAYDEPADFIFY-SKLGEIWTEG 761 L + ++L+++G + + ++S LR D +D F LG++W G Sbjct: 790 LLTEPQQILLEVGAGRTLATLAKQQTNSHTILSSLRH-PQDTQSDVAFLLQTLGQLWLAG 848 Query: 762 GTVDWQPFYFQESRKRVTLPAYAFDRQRYWHERK--EQAPQTVPRKKTPEQWLYRPVWKQ 819 ++DW+ FY + R+R+ LP Y F RQRYW + K EQ + +P + LY P W++ Sbjct: 849 VSIDWENFYTHQQRQRLPLPTYPFQRQRYWIDLKAGEQGSENIPSPR-----LYLPSWER 903 Query: 820 YYASPDYRLEDRGPDTFLLFIDDSGLGEGIQEALSAKGNRVCTVKMGAGFGRIHRDQYEI 879 P + ++ +L+F D+ G+ + I L A G+ V V G + + + + Sbjct: 904 SLPHPQVDIAEKRL-CWLVFTDNYGIYQEIINTLQAVGHDVIIVSQGEKYDQPAYRTFTV 962 Query: 880 DPDNAEHYLQVFRQVFQTGHPVWKIVHMWSSREYMPDSGGFYSLLHMGKSFGMIGIHQQI 939 +P N++ +++++ + I+++W + SLL++ ++ I ++I Sbjct: 963 NPQNSQDFVELWSDLELRELIPHHILYLWDLTDLQQQP---LSLLYLAQAISSQSIEREI 1019 Query: 940 QLTVVTSAFQSVMGNEVLTPSNAAATGAVHVIQQELQNVRTALIELAGEDTGKYDQAALE 999 LT+VT+ Q ++GNE + P A G VI QE+ + ++++ ++ + Sbjct: 1020 TLTLVTNDGQLLLGNENIQPMKATVWGMGKVISQEIPQLTCRCVDISLSTVASTNEQIAQ 1079 Query: 1000 LLLEEFIKPGPERFLAVRGRRKWVRAFEPMQMDHPADLKQKRDGVHVIXXXXXXXXXXXX 1059 L+ E + + +A RG +W + ++P+ MD Q + VH Sbjct: 1080 QLITECLNNQNDSVVAYRGNYRWNQIYKPLLMDD----AQSKISVH-------------- 1121 Query: 1060 XXXXEQGAGTLIL----TGRTSFPPEAEWQERLALYPGNDIINQKIRKIIELQEQGAQVY 1115 +G +IL TG + E + + L +D+I + +++ L G Sbjct: 1122 -----EGGNYVILGDLTTGLGTVFAEFLMKNSVRLVLLSDVITETLKQ--SLDNVGIDYL 1174 Query: 1116 LYQVQVSDEKRMNGLFTSIEHTHGKIQGVIYSAGTVVSDFFHNSISGITREMCEAEFEAK 1175 + ++ + + E G+I GV YS + ++ + +T + E + K Sbjct: 1175 SLNIDITKQAELENAIAQAETKFGQINGVFYST-PMSNEHSMAFLPQLTTKHWEYNYRTK 1233 Query: 1176 IRGLIILERMIRGKDIEYCMVNSSISTILGGIGLAAYTAANQFMDSFVQMMNQQQNRTRW 1235 I+GL +L ++R K +++C++ SS+ST+LGG+GLA Y AAN +D F N Q ++ W Sbjct: 1234 IQGLCVLAEVLRDKPLDFCVLQSSLSTVLGGLGLAVYAAANAVIDMFAIQQN-QNSKFPW 1292 Query: 1236 MAVDWDAWNFSASDKAGGTAANERLDQFIHPAEGGAVIKALFQVMNKTEHIVVSTTELEP 1295 ++++WDA + A + + PAE + + + + E +VV+ ++L+ Sbjct: 1293 ISINWDACRSDLETDINHSFAANLVTLALTPAEVWQSTQHIIK-LGLPESVVVTKSDLDK 1351 Query: 1296 RLALWVNHSRNNEPGSQRESRKELSIEQLLQERI--------------REATGLSGMGAD 1341 RL WV N ++ E+ + QL E I ++ G+S +G + Sbjct: 1352 RLEKWVT---NTPTKTKTETNNSYTRPQLTNEYIAPRDEIETAIAQIWQDLLGISPIGIN 1408 Query: 1342 ENFFDAG 1348 ++FFD G Sbjct: 1409 DSFFDLG 1415 >all2635 [Q] COG3321 Polyketide synthase modules and related proteins Length = 1565 Score = 536 bits (1381), Expect = e-151, Method: Compositional matrix adjust. Identities = 298/668 (44%), Positives = 402/668 (60%), Gaps = 36/668 (5%) Query: 4 KIAIIGLACRVPGADTPAAFWHQIVNGVESIRTFKDEELTASGISADILNHPQYVKRGAV 63 ++AI+G+A R PGA FW + NG+ SI+ +E+L A+G+ A+ L YV+ A Sbjct: 38 EVAIVGMAGRFPGAKNVDEFWDNLKNGINSIKFLSNEDLLANGVKAEDLEKQNYVRAYAS 97 Query: 64 IENADCFDAGFFRYTAKDAEITDPQHRAFLECAWEALEDAGCVQDLEKYP--VGVYASSC 121 + D FDAGFF Y+ ++AEI DPQHR FLECAWEALE+AG D E+Y + VY + Sbjct: 98 LAGIDEFDAGFFGYSPREAEILDPQHRLFLECAWEALENAG--YDSEQYSGNIAVYGGAA 155 Query: 122 ISSYVLNLYSDPELMGRLGHVQIGIGNEKDFLASKVSYKLGLRGPSVNVQTACSSSLVAV 181 ++SY++NL S+ Q+ I N + ++VSYKL L G S +QT CS+SLV+V Sbjct: 156 LNSYLVNLASNSNYRENSDRTQVVISNVMGLMPTRVSYKLNLTGASCGIQTGCSTSLVSV 215 Query: 182 HMASQSLLNGECDLALAGGVTIRSEQRAGYMYQKEGMVSPDGHCRVFDKDSKGTVFGNGL 241 H+A QSLLN ECD+ALAGGV+I ++AGY+YQ++G++SPDG+CR FD ++KGTVFGNG+ Sbjct: 216 HIACQSLLNKECDIALAGGVSIGIGEKAGYLYQEDGVLSPDGYCRAFDVNAKGTVFGNGV 275 Query: 242 GIVVLKRLADAVRDRDNIQAVICGTAVNNDGDHKIGFTAPSPVGQAQVIHEALSVAGVAP 301 GIVVLKRL DA++D D+I A+I TA+NNDG K+G TAPS GQA+ I AL+ A + P Sbjct: 276 GIVVLKRLRDAIQDGDHIYAIIKATAINNDGSQKVGLTAPSVTGQAKAITTALTKAKINP 335 Query: 302 REISYIETHGTGTELGDAIEIKALKEVFQAETGPAQFCAIGSVKPNIGHLDTAAGIIGLI 361 I YIETHGTGT LGD IEI AL + F T QFCA+GSVK NIGHLD AAGI GLI Sbjct: 336 ETIQYIETHGTGTALGDPIEIAALTKAFSPHTHQKQFCAVGSVKTNIGHLDAAAGISGLI 395 Query: 362 KTTLAMKNQVIPVCINHETPDPKLSLEDSPFYVNTASRPWKEVSAAPKAGVSSFGIGGTN 421 KT LA+K++ IP +N +P++ +SPF+VNT PW +AGVSSFG+GGTN Sbjct: 396 KTALALKHKQIPPSLNFTAANPQIDFANSPFFVNTQLTPWINHQHPRRAGVSSFGMGGTN 455 Query: 422 AHIILEEAPS---IASDASAKQNHVFLFSAKTLKSLEDTCRNMADFFGNHSTLHPADVAY 478 AH ILEEAP+ I + H+ SAK+ K+LE N+A H L+ ADVAY Sbjct: 456 AHAILEEAPTQFKIQNSKFKINYHLLCLSAKSEKALEQATINLATHLQKHPELNLADVAY 515 Query: 479 TLQTGRKHFPYRKMVVSSSLEEAAQWLR-TGSSQTECKGRE--EVPVAFFFPAEQRDMLR 535 TLQ GR+ F +R+ +V + +A + L +SQ E E + F FP + L Sbjct: 516 TLQIGRRAFNHRRCLVCQTPAQAIEILTGVDASQLLSYSPENTEPSIVFMFPGQGSQYLN 575 Query: 536 IGYELYQKETRFASIIDTYLSNERILHTLAGLDLQQILAGSRHGN-------------QE 582 +G ELY E F ID +L G DL IL + N + Sbjct: 576 MGQELYNTEPVFRKEID---HCSELLQPHLGCDLPSILFKQDNENSPSPQSPVPNLNYEL 632 Query: 583 RL--YTVLGQFIY--------QCALADYLVTLGIRKEVLIAEGNGVLPAVYVSGALSMND 632 R+ Y +L Q Y + ALA ++ GI+ + +I G A ++G ++ D Sbjct: 633 RITNYELLTQTTYAQPALFAVEYALAKLWLSYGIQPQAMIGHSIGEYVAATLAGVFTLAD 692 Query: 633 LIRIILIR 640 + I+ R Sbjct: 693 ALAIVAQR 700 Score = 232 bits (592), Expect = 3e-60, Method: Compositional matrix adjust. Identities = 184/675 (27%), Positives = 303/675 (44%), Gaps = 57/675 (8%) Query: 743 DEPADFIFYSK-LGEIWTEGGTVDWQPFYFQESRKRVTLPAYAFDRQRYWHER------K 795 D +D K LG++W G T++W Y Q+ R+R+ LP Y F+RQRYW ER Sbjct: 877 DTQSDVALICKTLGQLWLRGVTINWSELYTQQQRRRLPLPTYPFERQRYWVERDTLPETT 936 Query: 796 EQAPQTVPRKKTPEQWLYRPVWKQYYASPDYR-LEDRGPDTFLLFIDDSGLGEGIQEALS 854 +T+ +++ W Y P W+Q P R +L+F GE + + L Sbjct: 937 SNTSKTLQKQEQISNWFYLPSWRQ---KPLLRSAAPLNKQRYLVFCHAGNAGERLVQHLQ 993 Query: 855 AKGNRVCTVKMGAGFGRIHRDQYEIDPDNAEHYLQVFRQVFQTGHPVWKIVHMWSSREYM 914 G V TVK G GF + D Y I P N E Y ++ Q+ I+H W+ +E Sbjct: 994 ETGQEVVTVKPGEGFTQ-EGDNYAIAPHNPEDYKTLWLQLQTDDKLPDVIIHSWTLQERT 1052 Query: 915 ----PDSGGFYSLLHMGKSFGMIGIHQQIQLTVVTSAFQSVMGNEVLTPSNAAATGAVHV 970 + GFYSLL + ++ + + V+T Q+V+GNE L P +A G V V Sbjct: 1053 NFQQQQNLGFYSLLWLTQALS----SSSLSIYVLTQQVQNVLGNENLNPDDATILGLVKV 1108 Query: 971 IQQELQNVRTALIELAGEDTGKYDQAALELLLEEFI-------KPGPERFLAVRGRRKWV 1023 I QE N+ I+++ D + Q E+ + + K G +A RG+ +W+ Sbjct: 1109 IPQEYPNLTCQHIDVSISDI-NFQQLVREINIPPVLSDTLPLEKGGLRMSVAYRGKTRWI 1167 Query: 1024 RAFEPMQMDHPADLKQKRDGVHVIXXXXXXXXXXXXXXXXEQGAGT-LILTGRTSFPPEA 1082 + F+P+ + P L GV+VI L+ GR+ P Sbjct: 1168 QEFQPISLPEPTQLPLITGGVYVIAGDLVEGLGLIYAKFLAATVNAKLVFLGRSDLPQPK 1227 Query: 1083 EWQERLALYPGNDIINQKIRKIIELQEQGAQVYLYQVQVSDEKRMNGLFTSIEHTHGKIQ 1142 EW LA + D ++ I+++ LQ QG + V +++ ++ GKI Sbjct: 1228 EWDNWLATHGRQDAVSHCIQQLQGLQAQGCEFLFTTVDLAEISQVEDAIAQALTRFGKIN 1287 Query: 1143 GVIYSAGTVVSDFFHNSISGITREMCEAEFEAKIRGLIILERMIRGKDIEYCMVNSSIST 1202 GVI++ V+ D I +T CE +F KI GL+ LE ++ + +++ ++ SS+S Sbjct: 1288 GVIHAG--VMGDRASCLIRNLTIPECEKQFHTKIHGLLALETALKNQPLDFFLLQSSLSA 1345 Query: 1203 ILGGIGLAAYTAANQFMDSFVQMMNQQQNRTRWMAVDWDAWNFSASDKAGGTAANERLDQ 1262 ++GGIG AAY AN FMD+ Q N T W++++WDA + + + G +D Sbjct: 1346 VVGGIGFAAYAGANCFMDAIAHQRTQNSN-THWISINWDAVSLAEITTSTGATL---IDL 1401 Query: 1263 FIHPAEGGAVIKALFQVMNKTEHIVVSTTEL------EPRLALWVNHSRNN------EPG 1310 + E V + + I VS +L +P NH+R P Sbjct: 1402 AMTSQEVWQVTERIL-AQPIAAQITVSPVDLASRQQSQPLEQSTTNHARPQITATYLPPS 1460 Query: 1311 SQRESRKELSIEQLLQERIREATGLSGMGADENFFDAGITSIDIVGMNDSIQQHINRPIL 1370 ++ E+R +E LL G++ +G ++NFF+ G S+ + +++ + Sbjct: 1461 NEIEARVTQVMESLL--------GIAPIGVNDNFFELGGHSLLAIQAVSQLREEFQVELP 1512 Query: 1371 ISSW-YEYPTIKKLA 1384 + + +E PTI +A Sbjct: 1513 MRQFLFESPTIGGIA 1527 >AGl2313 [Q] COG3321 Polyketide synthase modules and related proteins Length = 211 Score = 470 bits (1209), Expect = e-132, Method: Compositional matrix adjust. Identities = 0/641 (0%), Positives = 0/641 (0%), Gaps = 10/641 (1%) Query: 4 KIAIIGLACRVPGADTPAAFWHQIVNGVESIRTFKDEELTASGISADILNHPQYVKRGAV 63 + +A + T + T + A Sbjct: 28 SPFELLIAVLLSAQATDVSVNKATAKLYPVANTPAAMLELGVEGVKTYIKTIGLYNSKAE 87 Query: 64 IENADCFDAGFFRYTAKDAEITDPQHRAFLECAWEALEDAGCVQDLEKYPVGVYASSCIS 123 C + + + + C Sbjct: 88 NIIKTCRILLEQHNGEVPEDRAALEALPGVGRKTANVVLNTAFGWPTIAVDTHIFRVCNR 147 Query: 124 SYVLNLYSDPELMGRLGHVQIGIGNEKDFLASKVSYKLGLRGPSVNVQTACSSSLVAVHM 183 + + ++ +L V + + + L Sbjct: 148 TQFAPGKNVEQVEEKLLKVVPAEFKVDCHHWLILHGRYTCIARKPRCGSCIIEDLCEYKE 207 Query: 184 ASQSLLNGECDLALAGGVTIRSEQRAGYMYQKEGMVSPDGHCRVFDKDSKGTVFGNGLGI 243 Sbjct: 208 -- 265 Query: 244 VVLKRLADAVRDRDNIQAVICGTAVNNDGDHKIGFTAPSPVGQAQVIHEALSVAGVAPRE 303 Sbjct: 266 325 Query: 304 ISYIETHGTGTELGDAIEIKALKEVFQAETGPAQFCAIGSVKPNIGHLDTAAGIIGLIKT 363 Sbjct: 326 385 Query: 364 TLAMKNQVIPVCINHETPDPKLSLEDSPFYVNTASRPWKEVSAAPKAGVSSFGIGGTNAH 423 Sbjct: 386 445 Query: 424 IILEEAPSIASDASAKQ---NHVFLFSAKTLKSLEDTCRNMADFFGNHSTLHPADVAYTL 480 Sbjct: 446 505 Query: 481 QTGRKHFPYRKMVVSSSLEEAAQWL-RTGSSQTECKGREEVPVAFFFPAEQRDMLRIGYE 539 Sbjct: 506 - 564 Query: 540 LYQKETRFASIIDTYLSNERILHTLAGLDLQQILAGSRHGNQERLYTVLGQFIYQCALAD 599 Sbjct: 565 --- 621 Query: 600 YLVTLGIRKEVLIAEGNGVLPAVYVSGALSMNDLIRIILIR 640 Sbjct: 622 662 Score = 134 bits (336), Expect = 2e-30, Method: Compositional matrix adjust. Identities = 0/712 (0%), Positives = 0/712 (0%), Gaps = 99/712 (13%) Query: 711 ENRLLIKIGMESGTDGALKGMGVVS------LLRQQAYDEPADFIFYSKLGEIWTEGGTV 764 Sbjct: 804 -- 861 Query: 765 DWQPFYFQESRKRVTLPAYAFDRQRYW---HERKEQAPQTVPRKKTPEQWLYRPVWKQYY 821 Sbjct: 862 ----- 916 Query: 822 ASPDYRLEDRGPDTFLLFIDDSGLGEGIQEALSAKGNRVCTVKMGAGFGRIHRDQYEIDP 881 Sbjct: 917 ---- 972 Query: 882 DNAEHYLQVFRQVFQTGHPVWKIVHMWSSREYMPDSGGFYSLLHMGKSFGMIGIHQQIQL 941 Sbjct: 973 ---- 1028 Query: 942 TVVTSAFQSVMGNEVLTPSNAAATGAVHVIQQELQNVRTALIE-LAGEDTGKYDQAALEL 1000 Sbjct: 1029 -- 1086 Query: 1001 LLEEFIKPGPERFLAVRGRRKWVRAFEPMQMDHP-ADLKQKRDGVHVIXXXXXXXXXXXX 1059 Sbjct: 1087 --------- 1137 Query: 1060 XXXXEQGAGTLILTGRTSFPPEAEWQERLALYPGNDI-INQKIRKIIELQEQGAQVYLYQ 1118 Sbjct: 1138 ------------------ 1179 Query: 1119 VQVSDEKRMNGLFTSIEHTHGKIQGVIYS---------AGTVVSDFFHNSISGITREMCE 1169 Sbjct: 1180 ------- 1232 Query: 1170 AEFEAKIRGLIILERMIRGKDIEYCMVNSSISTILGGIGLAAYTAANQFMDSFVQMMNQQ 1229 Sbjct: 1233 --- 1289 Query: 1230 QNRTRWMAVDWDAWNFSASDK-------AGGTAANERLDQFIHPAEGGAVIKALFQVMNK 1282 Sbjct: 1290 ---- 1345 Query: 1283 TEHIVVSTTELEPRLALWVNHSRN----NEPGSQRESRKELSIEQLLQERIREATGLSGM 1338 Sbjct: 1346 ---- 1401 Query: 1339 GADENFFDAGITSIDIVGMNDSIQQHINRPILISS---WYEYPTIKKLAGYL 1387 Sbjct: 1402 -- 1451 >ML2353_1 [Q] COG3321 Polyketide synthase modules and related proteins Length = 1031 Score = 447 bits (1151), Expect = e-125, Method: Compositional matrix adjust. Identities = 267/665 (40%), Positives = 369/665 (55%), Gaps = 32/665 (4%) Query: 3 SKIAIIGLACRVPGADTPAAFWHQIVNGVESIRTFKDEELTASGISADILNHPQYVKRGA 62 + IA++G+A + PGA+ +AFW + G ESI T ++EL +G+S L P YV+R Sbjct: 6 NAIAVVGMAGKFPGANDVSAFWTNLRRGKESIVTLSEQELRDNGVSDKALADPAYVRRAP 65 Query: 63 VIENADCFDAGFFRYTAKDAEITDPQHRAFLECAWEALEDAGCVQDLEKYPVGVYASSCI 122 +++ D FDA FF A++ DPQHR FL+CAW ALEDAGC +GVY +S Sbjct: 66 LLDGIDEFDADFFGLPPLAAQVLDPQHRLFLQCAWHALEDAGCDPAQFDGSIGVYGTSSP 125 Query: 123 SSYVL-NLYS--DPELMGRLG----HVQIGIGNEKDFLASKVSYKLGLRGPSVNVQTACS 175 S Y+L NL S DP + G + + N+KDFLA+++S+ LRGPS+ VQTACS Sbjct: 126 SGYLLHNLLSHRDPHTVLAEGLNFDQFSLFLQNDKDFLATRISHAFNLRGPSIAVQTACS 185 Query: 176 SSLVAVHMASQSLLNGECDLALAGGVTIRSEQRAGYMYQKEGMVSPDGHCRVFDKDSKGT 235 SSLVA+H+A SLL+GECD+ALAGG ++ R GY + MVS GHCR FD + GT Sbjct: 186 SSLVALHLACLSLLSGECDMALAGGSSLCIPHRVGYWHSPGSMVSAVGHCRPFDVRADGT 245 Query: 236 VFGNGLGIVVLKRLADAVRDRDNIQAVICGTAVNNDGDHKIGFTAPSPVGQAQVIHEALS 295 VFG+G+ +V LK L A+ D I AVI G+A+NNDG K+G+ AP+P QA VI EA + Sbjct: 246 VFGSGVALVALKPLQAAIDASDRIHAVILGSAINNDGSMKMGYAAPNPAAQADVIAEAHA 305 Query: 296 VAGVAPREISYIETHGTGTELGDAIEIKALKEVFQAETGP-AQFCAIGSVKPNIGHLDTA 354 VAG+ +SY+ETHGTGT LGD IEI+ LK F+ P C +GSVK NIGHL+ A Sbjct: 306 VAGIDSSTVSYVETHGTGTPLGDPIEIQGLKTAFEVSQIPRPGPCVLGSVKSNIGHLEVA 365 Query: 355 AGIIGLIKTTLAMKNQVIPVCINHETPDPKLSLEDSPFYVNTASRPWKEVSAAPKAGVSS 414 AGI GLIKT L +KN+ IP +++ +P+ +L L+ +PF V + PWK +AGVSS Sbjct: 366 AGIAGLIKTILCLKNKAIPATLHYTSPNRELRLDQTPFVVQSNYGPWKW-DGVRRAGVSS 424 Query: 415 FGIGGTNAHIILEEAPSIASDASAKQN-HVFLFSAKTLKSLEDTCRNMADFFGNHSTLHP 473 FG+GGTN H++LEEA AS +A V L SA+T +L ++ +A Sbjct: 425 FGVGGTNVHVVLEEASVEASTVAASTGPQVILLSAQTAAALGESREALATVLEKPGAPDL 484 Query: 474 ADVAYTLQTGRKHFPYRKMVVSSSL-----------------EEAAQWLRTGSSQTECKG 516 +DVAYTL RKH VV E A R+ ++ G Sbjct: 485 SDVAYTLAGRRKHNITMAAVVRDREHAVTVLRAAEHDNVFVGESGADTGRSAAASITTLG 544 Query: 517 REEVPVAFFFPAEQRDMLRIGYELYQKETRFASIIDTYLSNERILHTLAGLDLQQILAGS 576 + V F FP + + + LY E+ FA DT + R + LDL + Sbjct: 545 SDR--VVFLFPGQGAQHVGMAKGLYDTESVFAEHFDTCSAGFR--EAMDDLDLHSAIFNG 600 Query: 577 RHGNQERL-YTVLGQFIYQCALADYLVTLGIRKEVLIAEGNGVLPAVYVSGALSMNDLIR 635 + ER+ + F + ALA + + G+ I G A ++G + I+ Sbjct: 601 TAIDLERIDRSQPALFTVEYALAKLVESFGVGAGAYIGYSTGEYIAATLAGVFDLETAIK 660 Query: 636 IILIR 640 + +R Sbjct: 661 TVSLR 665 >AGl2329 [Q] COG3321 Polyketide synthase modules and related proteins Length = 211 Score = 444 bits (1141), Expect = e-124, Method: Compositional matrix adjust. Identities = 0/700 (0%), Positives = 0/700 (0%), Gaps = 28/700 (4%) Query: 4 KIAIIGLACRVPGADTPAAFWHQIVNGVESIRTFKDEELTASGISADILNHPQYVKRGAV 63 ++ A + K T ++ N + + Sbjct: 39 SAQATDVSVNKATAKLYPVANTPAAMLELGVEGVKTYIKTIGLYNSKAENIIKTCRILLE 98 Query: 64 IENADCFDAGFFRYTAKDAEITDPQHRAFLECAWEALEDAGCVQDLEKYPVGVYASSCIS 123 N + + W + + + + Sbjct: 99 QHNGEVPEDRAALEALPGVGRKTANVVLNTAFGWPTIAVDTHIFRVCNRTQFAPGKNVEQ 158 Query: 124 SYVLNLYSDPELMGRLGHVQIGIGNEKDFLASKVSYKLGLRGPSVNVQTACSSSLVAVHM 183 Sbjct: 159 218 Query: 184 ASQSLLNGECDLALAGGVTIRSEQRAGYMYQKEGMVSPDGHCRVFDKDSKGTVFGNGLGI 243 Sbjct: 219 278 Query: 244 VVLKRLADAVRDRDNIQAVICGTAVNNDGDHKIGFTAPSPVGQAQVIHEALSVAGVAPRE 303 Sbjct: 279 338 Query: 304 ISYIETHGTGTELGDAIEIKALKEVFQAETGPA-----QFCAIGSVKPNIGHLDTAAGII 358 Sbjct: 339 ---- 394 Query: 359 GLIKTTLAMKNQVIPVCINHETPDPKLSLEDSPFYVNTASRPWKEVSAAP-KAGVSSFGI 417 Sbjct: 395 454 Query: 418 GGTNAHIILEEAPSIASDASAKQNHVFL----FSAKTLKSLEDTCRNMADFFGNHSTLHP 473 Sbjct: 455 514 Query: 474 ADVAYTLQTGRKHFPYRKMVVSSSLEEAAQWLRTGSSQTECKG---REEVPVAFFFPAEQ 530 Sbjct: 515 574 Query: 531 RDMLRIGYELYQKETRFASIIDTYLSNERILHTLAGLDLQQILAGSRHGNQ-ERLYTVLG 589 Sbjct: 575 - 633 Query: 590 QFIYQCALADYLVTLGIRKEVLIAEGNGVLPAVYVSGALSMNDLIRIILIRQTWLNAAGE 649 Sbjct: 634 - 692 Query: 650 QQSL--------LAIELASLLKILPVQTPEAEMLAGGLRV 681 Sbjct: 693 732 Score = 151 bits (382), Expect = 8e-36, Method: Compositional matrix adjust. Identities = 0/666 (0%), Positives = 0/666 (0%), Gaps = 52/666 (7%) Query: 754 LGEIWTEGGTVDWQPFYFQESRKRVTLPAYAFDRQRYW----HERKEQAPQTVPRKKTPE 809 Sbjct: 873 -- 930 Query: 810 QWLYRPVWKQYYASPDYRLEDRGPDTFLLFIDDS--GLGEGIQEALSAKGNRVCTVKMGA 867 Sbjct: 931 ----------- 979 Query: 868 GFGRIHRDQYEIDPDNAEHYLQVFRQVFQTGHPVWKIVHMWSSREY-MPDSGGFYSLLHM 926 Sbjct: 980 - 1038 Query: 927 GKSFGMIGIHQQIQLTVVTSAFQSVMGNEVLTPSNAAATGAVHVIQQELQNVRTALIELA 986 Sbjct: 1039 --- 1095 Query: 987 GEDTGKYDQAALELLLEEFIKPGPERFLAVRGRRKWVRAFEPMQMDHPAD-LKQKRDGVH 1045 Sbjct: 1096 -- 1153 Query: 1046 VIXXXXXXXXXXXXXXXXEQGAGTLILTGRTSFPPEAEWQERLALYPGNDIINQKIRKII 1105 Sbjct: 1154 1213 Query: 1106 ELQEQGAQVYLYQVQVSDEKRMNGLFTSIEHTHGKIQGVIYSAGTVVSDFFHNSISGITR 1165 Sbjct: 1214 -- 1271 Query: 1166 EMCEAEFEAKIRGLIILERMIRGKDIEYCMVNSSISTILGGIGLAAYTAANQFMDSFVQM 1225 Sbjct: 1272 - 1330 Query: 1226 MNQQQNRTRWMAVDWDAWNFSASDKAGGTAANERLDQFIHPAEGGAVIKALFQVMNKTE- 1284 Sbjct: 1331 --------- 1381 Query: 1285 -HIVVSTTELEPRLALWVNHSRNNEPGSQRESRKELS---------IEQLLQERIREATG 1334 Sbjct: 1382 1441 Query: 1335 LSGMGADENFFDAGITSIDIVGMNDSIQQHINRPILISS-WYEYPTIKKLAGYLQGEEKE 1393 Sbjct: 1442 - 1500 Query: 1394 ARSTQA 1399 Sbjct: 1501 1506 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.318 0.135 0.398 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 107,516,783 Number of extensions: 4673880 Number of successful extensions: 10428 Number of sequences better than 1.0e-05: 112 Number of HSP's gapped: 9988 Number of HSP's successfully gapped: 130 Length of query: 1426 Length of database: 38,378,431 Length adjustment: 119 Effective length of query: 1307 Effective length of database: 24,653,685 Effective search space: 32222366295 Effective search space used: 32222366295 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 122 (51.6 bits)